Supplemental antioxidants do not ameliorate colitis development in HLA-B27 transgenic rats despite extremely low glutathione levels in colonic mucosa

Inflammatory Bowel Diseases

Volumn 17, Issue 10, 2011, Pages 2065-2075

  Schepens, Marloes A A ^a,b   Vink, Carolien ^a,b   Schonewille, Arjan J ^a,b   Roelofs, Hennie M J ^c   Brummer, Robert Jan ^a,d   Van Der Meer, Roelof ^a,b,e   Bovee Oudenhoven, Ingeborg M J ^a,b  

^a TOP INSTITUTE FOOD AND NUTRITION   (Netherlands)

^b NIZO FOOD RESEARCH   (Netherlands)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^d ÖREBRO UNIVERSITY   (Sweden)

^e WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

antioxidants; calcium; colitis; HLA B27 transgenic rats; oxidative stress

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; CALCIUM; GLUTATHIONE; HLA B27 ANTIGEN; INTERLEUKIN 1BETA; MYELOPEROXIDASE; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; COLITIS; COLON MUCOSA; CONTROLLED STUDY; DIARRHEA; DIET SUPPLEMENTATION; FEMALE; INTESTINE MUCOSA PERMEABILITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIOXIDANTS; BIOLOGICAL MARKERS; CALCIUM, DIETARY; CELL MEMBRANE PERMEABILITY; COLITIS; DIETARY SUPPLEMENTS; DISEASE MODELS, ANIMAL; FEMALE; GLUTATHIONE; HLA-B27 ANTIGEN; INTESTINAL MUCOSA; OXIDATIVE STRESS; RATS; RATS, TRANSGENIC; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 80052700989     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1002/ibd.21584     Document Type: Article

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