Infection after acute ischemic stroke: Risk factors, biomarkers, and outcome

Stroke Research and Treatment

Volumn , Issue , 2011, Pages

  Wartenberg, Katja E ^a   Stoll, Anett ^b   Funk, Andreas ^c   Meyer, Andreas ^c   Schmidt, J Michael ^d   Berrouschot, Joerg ^b  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b Klinik für Neurologie   (Germany)

^c Klinikum Altenburger Land   (Germany)

^d NEUROLOGICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ASCORBIC ACID; C REACTIVE PROTEIN; HLA DR ANTIGEN; INFUSION FLUID; INTERLEUKIN 6; LIPOPOLYSACCHARIDE BINDING PROTEIN; PROCALCITONIN;

ACUTE DISEASE; AGED; AGING; ANTIGEN EXPRESSION; ARTICLE; BODY TEMPERATURE; BRAIN ISCHEMIA; CONFIDENCE INTERVAL; CYTOKINESIS; DIFFUSION WEIGHTED IMAGING; DISEASE COURSE; FEMALE; GASTRITIS; HUMAN; INFECTION; INSULA; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; MONOCYTE; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; OUTCOME ASSESSMENT; PATIENT MONITORING; PNEUMONIA; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; RISK FACTOR; SEPSIS; UPPER RESPIRATORY TRACT INFECTION; URINARY TRACT INFECTION;

EID: 80052694216     PISSN: None     EISSN: 20420056     Source Type: Journal    
DOI: 10.4061/2011/830614     Document Type: Article

References (37)

1. Hong K. S., Kang D. W., Koo J. S., Yu K. H., Han M. K., Cho Y. J., Park J. M., Bae H. J., Lee B. C., Impact of neurological and medical complications on 3-month outcomes in acute ischaemic stroke European Journal of Neurology 2008 15 12 1324 1331
2. Johnston K. C., Li J. Y., Lyden P. D., Hanson S. K., Feasby T. E., Adams R. J., Faught R. E., Haley E. C., Medical and neurological complications of ischemic stroke: experience from the ranttas trial. Ranttas investigators Stroke 1998 29 2 447 453 (Pubitemid 28086690)
3. Katzan I. L., Cebul R. D., Husak S. H., Dawson N. V., Baker D. W., The effect of pneumonia on mortality among patients hospitalized for acute stroke Neurology 2003 60 4 620 625 (Pubitemid 36246079)
4. Langhorne P., Stott D. J., Robertson L., MacDonald J., Jones L., McAlpine C., Dick F., Taylor G. S., Murray G., Medical complications after stroke: a multicenter study Stroke 2000 31 6 1223 1229 (Pubitemid 30351237)
5. Ovbiagele B., Hills N. K., Saver J. L., Johnston S. C., Frequency and determinants of pneumonia and urinary tract infection during stroke hospitalization Journal of Stroke and Cerebrovascular Diseases 2006 15 5 209 213 (Pubitemid 44332971)
6. Tirschwell D. L., Kukull W. A., Longstreth W. T. Jr., Medical complications of ischemic stroke and length of hospital stay: experience in Seattle, Washington Journal of Stroke and Cerebrovascular Diseases 1999 8 5 336 343
7. Davenport R. J., Dennis M. S., Wellwood I., Warlow C. P., Complications after acute stroke Stroke 1996 27 3 415 420 (Pubitemid 26081434)
8. Sellars C., Bowie L., Bagg J., Sweeney M. P., Miller H., Tilston J., Langhorne P., Stott D. J., Risk factors for chest infection in acute stroke: a prospective cohort study Stroke 2007 38 8 2284 2291 (Pubitemid 47457570)
9. Dirnagl U., Klehmet J., Braun J. S., Harms H., Meisel C., Ziemssen T., Prass K., Meisel A., Stroke-induced immunodepression: experimental evidence and clinical relevance Stroke 2007 38 2 770 773 (Pubitemid 46184257)
10. Chamorro A., Urra X., Planas A. M., Infection after acute ischemic stroke: a manifestation of brain-induced immunodepression Stroke 2007 38 3 1097 1103 (Pubitemid 46568484)
11. Gonsalves M. D., Sakr Y., Early identification of sepsis Current Infectious Disease Reports 12 329 335
12. Ringleb P. A., Bousser M. G., Ford G., Bath P., Brainin M., Caso V., Cervera.., Chamorro A., Cordonnier C., Csiba L., Davalos A., Diener H. C., Ferro J., Hacke W., Hennerici M., Kaste M., Langhorne P., Lees K., Leys D., Lodder J., Markus H. S., Mas J. L., Mattle H. P., Muir K., Norrving Bo., Obach V., Paolucci S., Ringelstein E. B., Schellinger P. D., Sivenius J., Skvortsova V., Sunnerhagen K. S., Thomassen L., Toni D., Von Kummer R., Wahlgren N. G., Walker M. F., Wardlaw J., Guidelines for management of ischaemic stroke and transient ischaemic attack 2008 Cerebrovascular Diseases 2008 25 5 457 507 (Pubitemid 351754643)
13. Adams H. P. Jr., Del Zoppo G., Alberts M. J., Bhatt D. L., Brass L., Furlan A., Grubb R. L., Higashida R. T., Jauch E. C., Kidwell C., Lyden P. D., Morgenstern L. B., Qureshi A. I., Rosenwasser R. H., Scott P. A., Guidelines for the early management of adults with ischemic stroke: a guideline from the American heart association/American stroke association stroke council, clinical cardiology council, cardiovascular radiology and intervention council, and the atherosclerotic peripheral vascular disease and quality of care outcomes in research interdisciplinary working groups: the american academy of neurology affirms the value of this guideline as an educational tool for neurologists Stroke 2007 38 5 1655 1711 (Pubitemid 46691097)
14. Cincura C., Pontes-Neto O. M., Neville I. S., Mendes H. F., Menezes D. F., Mariano D. C., Pereira I. F., Teixeira L. A., Jesus P. A. P., De Queiroz D. C. L., Pereira D. F., Pinto E., Leite J. P., Lopes A. A., Oliveira-Filho J., Validation of the national institutes of health stroke scale, modified rankin scale and barthel index in Brazil: the role of cultural adaptation and structured interviewing Cerebrovascular Diseases 2009 27 2 119 122
15. Grau A. J., Buggle F., Steichen-Wiehn C., Heindl S., Banerjee T., Seitz R., Winter R., Forsting M., Werle E., Bode C., Nawroth P. P., Becher H., Hacke W., Clinical and biochemical analysis in infection-associated stroke Stroke 1995 26 9 1520 1526
16. Haeusler K. G., Schmidt W. U., Fohring F., Meisel C., Helms T., Jungehulsing G. J., Nolte C. H., Schmolke K., Wegner B., Meisel A., Dirnagl U., Villringer A., Volk H. D., Cellular immunodepression preceding infectious complications after acute ischemic stroke in humans Cerebrovascular Diseases 2008 25 1-2 50 58 (Pubitemid 351280375)
17. Klehmet J., Harms H., Richter M., Prass K., Volk H. D., Dirnagl U., Meisel A., Meisel C., Stroke-induced immunodepression and post-stroke infections: lSSessons from the preventive antibacterial therapy in stroke trial Neuroscience 2009 158 3 1184 1193
18. Prass K., Meisel C., Hoflich C., Braun J., Halle E., Wolf T., Ruscher K., Victorov I. V., Priller J., Dirnagl U., Volk H. D., Meisel A., Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke t helper cell type 1-like immunostimulation Journal of Experimental Medicine 2003 198 5 725 736 (Pubitemid 37087772)
19. Vogelgesang A., Grunwald U., Langner S., Jack R., Broker B. M., Kessler C., Dressel A., Analysis of lymphocyte subsets in patients with stroke and their influence on infection after stroke Stroke 2008 39 1 237 241
20. Chamorro A., Amaro S., Vargas M., Obach V., Cervera A., Torres F., Planas A. M., Interleukin 10, monocytes and increased risk of early infection in ischaemic stroke Journal of Neurology, Neurosurgery and Psychiatry 2006 77 11 1279 1281 (Pubitemid 44654763)
21. Hug A., Dalpke A., Wieczorek N., Giese T., Lorenz A., Auffarth G., Liesz A., Veltkamp R., Infarct volume is a major determiner of post-stroke immune cell function and susceptibility to infection Stroke 2009 40 10 3226 3232
22. Villar J., Perez-Mendez L., Espinosa E., Flores C., Blanco J., Muriel A., Basaldua S., Muros M., Blanch L., Artigas A., Kacmarek R. M., Serum lipopolysaccharide binding protein levels predict severity of lung injury and mortality in patients with severe sepsis PLoS ONE 2009 4 8, article e6818
23. Dieler C., Frohlich E., Bourquain H., Holle R., von Kummer R., Simple volumetry of ischemic cerebral infarction using computerized tomography.interobserver and method comparison Rofo 1999 171 279 282
24. Adams H. P. Jr., Bendixen B. H., Kappelle L. J., Biller J., Love B. B., Gordon D. L., Marsh E. E. III, Classification of subtype of acute ischemic stroke: definitions for use in a multicenter clinical trial. Toast. trial of org 10172 in acute stroke treatment. Stroke 1993 24 1 35 41 (Pubitemid 23014379)
25. hhttp://www.awmf.org/leitlinien/aktuelle-leitlinien/ll-liste/ deutsche-gesellschaft-fuer-infektiologie-dgi.htm
26. Schwarz S. A., Sick C., Meairs S., Hennerici M. G., Effects of prophylactic antibiotic therapy with mezlocillin plus sulbactam on the incidence and height of fever after severe acute ischemic stroke: the mannheim infection in stroke study (miss) Stroke 2008 39 4 1220 1227 (Pubitemid 351440694)
27. Harms H. P. K., Meisel C., Klehmet J., Rogge W., Drenckhahn C., Ghler J., Bereswill S., Gbel U., Wernecke K. D., Wolf T., Arnold G., Halle E., Volk H. D., Dirnagl U., Meisel A., Preventive antibacterial therapy in acute ischemic stroke: a randomized controlled trial PLoS ONE 2008 3, article e2158
28. Chamorro A. H. J., Obach V., Vargas M., Revilla M., Torres F., Cervera A., Planas A. M., Mensa J., The early systemic prophylaxis of infection after stroke study: a randomized clinical trial Stroke 2005 36 7 1495 1500 (Pubitemid 40967519)
29. Lampl Y., Boaz M., Gilad R., Lorberboym M., Dabby R., Rapoport A., Anca-Hershkowitz M., Sadeh M., Minocycline treatment in acute stroke: an open-label, evaluator-blinded study Neurology 2007 69 14 1404 1410 (Pubitemid 47511461)
30. Liesz A., Hagmann S., Zschoche C., Adamek J., Zhou W., Sun LI., Hug A., Zorn M., Dalpke A., Nawroth P., Veltkamp R., The spectrum of systemic immune alterations after murine focal ischemia: immunodepression versus immunomodulation Stroke 2009 40 8 2849 2858
31. Chamorro A., Amaro S., Vargas M., Obach V., Cervera A., Gomez-Choco M., Torres F., Planas A. M., Catecholamines, infection, and death in acute ischemic stroke Journal of the Neurological Sciences 2007 252 1 29 35 (Pubitemid 44909185)
32. Palasik W. F. U., Lechowicz W., Czartoryska B., Krzesiewicz M., Lugowska A., Assessment of relations between clinical outcome of ischemic stroke and activity of inflammatory processes in the acute phase based on examination of selected parameters European Neurology 2005 53 4 188 193 (Pubitemid 41404747)
33. Kwan J., Hand P., Infection after acute stroke is associated with poor short-term outcome Acta Neurologica Scandinavica 2007 115 5 331 338 (Pubitemid 46699431)
34. Vermeij F. H., Scholte op Reimer W. J., De Man P., Stroke-associated infection is an independent risk factor for poor outcome after acute ischemic stroke: data from the Netherlands stroke survey Cerebrovascular Diseases 2009 27 5 465 471
35. Heuschmann P. U., Kolominsky-Rabas P. L., Misselwitz B., Hermanek P., Leffmann C., Janzen R. W. C., Rother J., Buecker-Nott H. J., Berger K., Predictors of in-hospital mortality and attributable risks of death after ischemic stroke: the German stroke registers study group Archives of Internal Medicine 2004 164 16 1761 1768 (Pubitemid 39215645)
36. Hilker R., Poetter C., Findeisen N., Sobesky J., Jacobs A., Neveling M., Heiss W. D., Nosocomial pneumonia after acute stroke: implications for neurological intensive care medicine Stroke 2003 34 4 975 981 (Pubitemid 36402972)
37. Walter U., Knoblich R., Steinhagen V., Donat M., Benecke R., Kloth A., Predictors of pneumonia in acute stroke patients admitted to a neurological intensive care unit Journal of Neurology 2007 254 10 1323 1329 (Pubitemid 350112314)