-
1
-
-
0029133235
-
Metabolic effects of metformin in non-insulin-dependent diabetes mellitus
-
Stumvoll M., Nurjhan N., Perriello G., Dailey G., Gerich J.E. Metabolic effects of metformin in non-insulin-dependent diabetes mellitus. N Engl J Med 1995, 333:550-554.
-
(1995)
N Engl J Med
, vol.333
, pp. 550-554
-
-
Stumvoll, M.1
Nurjhan, N.2
Perriello, G.3
Dailey, G.4
Gerich, J.E.5
-
2
-
-
0029819936
-
Metabolic effects of metformin on glucose and lactate metabolism in non insulin-dependent diabetes mellitus
-
Cusi K., Consoli A., DeFronzo R.A. Metabolic effects of metformin on glucose and lactate metabolism in non insulin-dependent diabetes mellitus. J Clin Endocrinol Metab 1996, 81:4059-4067.
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 4059-4067
-
-
Cusi, K.1
Consoli, A.2
DeFronzo, R.A.3
-
3
-
-
0022881373
-
Effect of metformin on peripheral insulin sensitivity in non insulin dependent diabetes mellitus
-
Prager R., Schernthaner G., Graf H. Effect of metformin on peripheral insulin sensitivity in non insulin dependent diabetes mellitus. Diabet Metab 1986, 12:346-350.
-
(1986)
Diabet Metab
, vol.12
, pp. 346-350
-
-
Prager, R.1
Schernthaner, G.2
Graf, H.3
-
4
-
-
0025837055
-
Mechanism of metformin action in obese and lean noninsulin-dependent diabetic subjects
-
DeFronzo R.A., Barzilai N., Simonson D.C. Mechanism of metformin action in obese and lean noninsulin-dependent diabetic subjects. J Clin Endocrinol Metab 1991, 73:1294-1301.
-
(1991)
J Clin Endocrinol Metab
, vol.73
, pp. 1294-1301
-
-
DeFronzo, R.A.1
Barzilai, N.2
Simonson, D.C.3
-
5
-
-
0033952266
-
Inhibitory effect of metformin on intestinal glucose absorption in the perfused rat intestine
-
Ikeda T., Iwata K., Murakami H. Inhibitory effect of metformin on intestinal glucose absorption in the perfused rat intestine. Biochem Pharmacol 2000, 59:887-890.
-
(2000)
Biochem Pharmacol
, vol.59
, pp. 887-890
-
-
Ikeda, T.1
Iwata, K.2
Murakami, H.3
-
6
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou G., Myers R., Li Y., Chen Y., Shen X., Fenyk-Melody J., et al. Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest 2001, 108:1167-1174.
-
(2001)
J Clin Invest
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
Chen, Y.4
Shen, X.5
Fenyk-Melody, J.6
-
7
-
-
0345866860
-
Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2, and 3 (SLC22A1-3)
-
Jonker J.W., Schinkel A.H. Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2, and 3 (SLC22A1-3). JEPET 2004, 308:2-9.
-
(2004)
JEPET
, vol.308
, pp. 2-9
-
-
Jonker, J.W.1
Schinkel, A.H.2
-
8
-
-
17444421115
-
Role of organic cation transporters in the renal handling of therapeutic agents and xenobiotics
-
Wright S.H. Role of organic cation transporters in the renal handling of therapeutic agents and xenobiotics. Toxicol Appl Pharmacol 2005, 204:309-319.
-
(2005)
Toxicol Appl Pharmacol
, vol.204
, pp. 309-319
-
-
Wright, S.H.1
-
9
-
-
38849148341
-
Effects of tetra-alkylammonium compounds with different affinities for organic cation transporters on the pharamacokinetics of metformin
-
Choi M.K., Jin Q.R., Jin H.E., Shim C.K., Cho D.Y., Shin J.G., et al. Effects of tetra-alkylammonium compounds with different affinities for organic cation transporters on the pharamacokinetics of metformin. Biopharm Drug Dispos 2007, 28:501-510.
-
(2007)
Biopharm Drug Dispos
, vol.28
, pp. 501-510
-
-
Choi, M.K.1
Jin, Q.R.2
Jin, H.E.3
Shim, C.K.4
Cho, D.Y.5
Shin, J.G.6
-
10
-
-
34248156160
-
Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action
-
Shu Y., Sheardown S.A., Brown C., Owen R.P., Zhang S., Castro R.A., et al. Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action. J Clin Invest 2007, 117:1422-1431.
-
(2007)
J Clin Invest
, vol.117
, pp. 1422-1431
-
-
Shu, Y.1
Sheardown, S.A.2
Brown, C.3
Owen, R.P.4
Zhang, S.5
Castro, R.A.6
-
11
-
-
0036070666
-
Involvement of organic cation transporter 1 in hepatic and intestinal distribution of metformin
-
Wang D.S., Jonker J.W., Kato Y., Kusuhara H., Schinkel A.H., Sugiyama Y. Involvement of organic cation transporter 1 in hepatic and intestinal distribution of metformin. JPET 2002, 302:1-6.
-
(2002)
JPET
, vol.302
, pp. 1-6
-
-
Wang, D.S.1
Jonker, J.W.2
Kato, Y.3
Kusuhara, H.4
Schinkel, A.H.5
Sugiyama, Y.6
-
12
-
-
0037381942
-
Involvement of organic cation transporter 1 in the lactic acidosis caused by metformin
-
Wang D.S., Kusuhara H., Kato Y., Jonker J.W., Schinkel A.H., Sugiyama Y. Involvement of organic cation transporter 1 in the lactic acidosis caused by metformin. Mol Pharmacol 2003, 63:844-848.
-
(2003)
Mol Pharmacol
, vol.63
, pp. 844-848
-
-
Wang, D.S.1
Kusuhara, H.2
Kato, Y.3
Jonker, J.W.4
Schinkel, A.H.5
Sugiyama, Y.6
-
13
-
-
70549094220
-
A comparison of uptake of metformin and phenformin mediated by hOCT1 in human hepatocytes
-
Sogame Y., Kitamura A., Yabuki M., Komuro S. A comparison of uptake of metformin and phenformin mediated by hOCT1 in human hepatocytes. Biopharm Drug Dispos 2009, 30:476-484.
-
(2009)
Biopharm Drug Dispos
, vol.30
, pp. 476-484
-
-
Sogame, Y.1
Kitamura, A.2
Yabuki, M.3
Komuro, S.4
-
14
-
-
34547946755
-
Functional involvement of organic cation transporter 1 (OCT1/Oct1) in the hepatic uptake of organic cations in humans and rats
-
Umehara K.I., Iwatsubo T., Noguchi K., Kamimura H. Functional involvement of organic cation transporter 1 (OCT1/Oct1) in the hepatic uptake of organic cations in humans and rats. Xenobiotica 2007, 37:818-831.
-
(2007)
Xenobiotica
, vol.37
, pp. 818-831
-
-
Umehara, K.I.1
Iwatsubo, T.2
Noguchi, K.3
Kamimura, H.4
-
15
-
-
0029846754
-
Tissue-selective uptake of pravastatin in rats: contribution of a specific carrier-mediated uptake system
-
Yamazaki M., Tokui T., Ishigami M., Sugiyama Y. Tissue-selective uptake of pravastatin in rats: contribution of a specific carrier-mediated uptake system. Biopharm Drug Dispos 1996, 17:775-789.
-
(1996)
Biopharm Drug Dispos
, vol.17
, pp. 775-789
-
-
Yamazaki, M.1
Tokui, T.2
Ishigami, M.3
Sugiyama, Y.4
-
16
-
-
0027392882
-
Na+-independent multispecific anion transporter mediates active transport of pravastatin into rat liver
-
Yamazaki M., Suzuki H., Hanano M., Tokui T., Komai T., Sugiyama Y. Na+-independent multispecific anion transporter mediates active transport of pravastatin into rat liver. Am J Physiol 1993, 264:G36-G44.
-
(1993)
Am J Physiol
, vol.264
-
-
Yamazaki, M.1
Suzuki, H.2
Hanano, M.3
Tokui, T.4
Komai, T.5
Sugiyama, Y.6
-
17
-
-
0018628696
-
Metabolism of phenformin in the rat and guinea-pig
-
Guest D., King L.J., Parke D.V. Metabolism of phenformin in the rat and guinea-pig. Xenobiotica 1979, 9:681-693.
-
(1979)
Xenobiotica
, vol.9
, pp. 681-693
-
-
Guest, D.1
King, L.J.2
Parke, D.V.3
-
18
-
-
0017727138
-
A comparison of phenformin and metformin in the treatment of maturity onset diabetes
-
Cairns S.A., Shalet S., Marshall A.J., Hartog M. A comparison of phenformin and metformin in the treatment of maturity onset diabetes. Diabet Metab 1977, 3:183-188.
-
(1977)
Diabet Metab
, vol.3
, pp. 183-188
-
-
Cairns, S.A.1
Shalet, S.2
Marshall, A.J.3
Hartog, M.4
-
19
-
-
0022473938
-
The effects of diabetes mellitus, exercise, and single doses of biguanides upon lactate metabolism in man
-
Fletcher P., Hirji M.R., Kuhn S., Alexander L., Mucklow J.C. The effects of diabetes mellitus, exercise, and single doses of biguanides upon lactate metabolism in man. Br J Clin Pharmacol 1986, 21:691-699.
-
(1986)
Br J Clin Pharmacol
, vol.21
, pp. 691-699
-
-
Fletcher, P.1
Hirji, M.R.2
Kuhn, S.3
Alexander, L.4
Mucklow, J.C.5
-
20
-
-
0034659785
-
Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain
-
Owen M.R., Doran E., Halestrap A.P. Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain. Biochem J 2000, 348:607-614.
-
(2000)
Biochem J
, vol.348
, pp. 607-614
-
-
Owen, M.R.1
Doran, E.2
Halestrap, A.P.3
-
21
-
-
0034614420
-
Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I
-
El-Mir M.Y., Nogueira V., Fontaine E., Averet N., Rigoulet M., Leverve X. Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I. J Biol Chem 2000, 275:223-228.
-
(2000)
J Biol Chem
, vol.275
, pp. 223-228
-
-
El-Mir, M.Y.1
Nogueira, V.2
Fontaine, E.3
Averet, N.4
Rigoulet, M.5
Leverve, X.6
-
22
-
-
0016749637
-
Pharmacokinetics of phenformin in man
-
Alkalay D., Khemani L., Wagner W.E., Bartlett M.F. Pharmacokinetics of phenformin in man. J Clin Pharmacol 1975, 15:446-448.
-
(1975)
J Clin Pharmacol
, vol.15
, pp. 446-448
-
-
Alkalay, D.1
Khemani, L.2
Wagner, W.E.3
Bartlett, M.F.4
-
23
-
-
0021053140
-
Influence of oxidation polymorphism on phenformin kinetics and dynamics
-
Oates N.S., Shah R.R., Idle J.R., Smith R.L. Influence of oxidation polymorphism on phenformin kinetics and dynamics. Clin Pharmacol Ther 1983, 34:827-834.
-
(1983)
Clin Pharmacol Ther
, vol.34
, pp. 827-834
-
-
Oates, N.S.1
Shah, R.R.2
Idle, J.R.3
Smith, R.L.4
-
24
-
-
0018703481
-
Pharmacokinetics of metformin after intravenous and oral administration to man
-
Pentikäinen P.J., Neuvonen P.J., Penttilä A. Pharmacokinetics of metformin after intravenous and oral administration to man. Eur J Clin 1979, 16:195-202.
-
(1979)
Eur J Clin
, vol.16
, pp. 195-202
-
-
Pentikäinen, P.J.1
Neuvonen, P.J.2
Penttilä, A.3
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