Biomarkers in overactive bladder: A new objective and noninvasive tool?

Advances in Urology

Volumn , Issue , 2011, Pages

  Antunes Lopes, Tiago ^a,b,c   Carvalho Barros, Sérgio ^b,c   Cruz, Célia Duarte ^b,c   Cruz, Francisco ^a,b,c   Martins Silva, Carlos ^a,b,c  

^a HOSPITAL DE SÃO JOÃO   (Portugal)

^b University of Porto   (Portugal)

^c UNIVERSITY OF PORTO   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 80052663719     PISSN: 16876369     EISSN: 16876377     Source Type: Journal    
DOI: 10.1155/2011/382431     Document Type: Review

References (72)

1. Irwin D. E., Milsom I., Hunskaar S., Reilly K., Kopp Z., Herschorn S., Coyne K., Kelleher C., Hampel C., Artibani W., Abrams P., Population-based survey of urinary incontinence, overactive bladder, and other lower urinary tract symptoms in five countries: results of the EPIC study European Urology 2006 50 6 1306 1315 (Pubitemid 44692945)
2. Abrams P., Cardozo L., Fall M., Griffiths D., Rosier P., Ulmsten U., Van Kerrebroeck P., Victor A., Wein A., The standardisation of terminology of lower urinary tract function: report from the standardisation sub-committee of the international continence society Neurourology and Urodynamics 2002 21 2 167 178 (Pubitemid 34195211)
3. Chapple C. R., Artibani W., Cardozo L. D., Castro-Diaz D., Craggs M., Haab F., Khullar V., Versi E., The role of urinary urgency and its measurement in the overactive bladder symptom syndrome: current concepts and future prospects British Journal of Urology International 2005 95 3 335 340 (Pubitemid 40283119)
4. Nixon A., Colman S., Sabounjian L., Sandage B., Schwiderski U. E., Staskin D. R., Zinner N., A validated patient reported measure of urinary urgency severity in overactive bladder for use in clinical trials Journal of Urology 2005 174 2 604 607 (Pubitemid 40981612)
5. Starkman J. S., Dmochowski R. R., Urgency assessment in the evaluation of overactive bladder (OAB) Neurourology and Urodynamics 2008 27 1 13 21
6. Hashim H., Abrams P., Is the bladder a reliable witness for predicting detrusor overactivity? Journal of Urology 2006 175 1 191 195
7. Liu H. T., Chancellor M. B., Kuo H. C., Decrease of urinary nerve growth factor levels after antimuscarinic therapy in patients with overactive bladder British Journal of Urology International 2009 103 12 1668 1672
8. Kuo H. C., Measurement of detrusor wall thickness in women with overactive bladder by transvaginal and transabdominal sonography International Urogynecology Journal and Pelvic Floor Dysfunction 2009 20 11 1293 1299
9. Cruz F., Heesakkers J., Khullar V., Tubaro A., Bladder wall thickness in overactive bladder: does it have a role? European Urology 2009 8 9, supplement 769 771
10. Oelke M., Hfner K., Jonas U., de la Rosette J. J., Ubbink D. T., Wijkstra H., Diagnostic accuracy of noninvasive tests to evaluate bladder outlet obstruction in men: detrusor wall thickness, uroflowmetry, postvoid residual urine, and prostate volume European Urology 2007 52 3 827 835 (Pubitemid 47126129)
11. Kessler T. M., Gerber R., Burkhard F. C., Studer U. E., Danuser H., Ultrasound assessment of detrusor thickness in men-can it predict bladder outlet obstruction and replace pressure flow study? Journal of Urology 2006 175 6 2170 2173 (Pubitemid 43668515)
12. Farag F. F., Martens F. M., D'Hauwers K. W., Feitz W. F., Heesakkers J. P., Near-infrared spectroscopy: a novel, noninvasive, diagnostic method for detrusor overactivity in patients with overactive bladder symptomsa preliminary and experimental study European Urology 2011 59 5 757 762
13. Allen S. J., Dawbarn D., Clinical relevance of the neurotrophins and their receptors Clinical Science 2006 110 2 175 191 (Pubitemid 43241479)
14. Steers W. D., Tuttle J. B., Mechanisms of disease: the role of nerve growth factor in the pathophysiology of bladder disorders Nature Clinical Practice Urology 2006 3 2 101 110 (Pubitemid 43239267)
15. Birder L. A., de Groat W. C., Mechanisms of disease: involvement of the urothelium in bladder dysfunction Nature Clinical Practice Urology 2007 4 1 46 54 (Pubitemid 46062986)
16. Levi-Montalcini R., Nerve growth factor Science 1975 187 4172 113
17. Pezet S., McMahon S. B., Neurotrophins: mediators and modulators of pain Annual Review of Neuroscience 2006 29 507 538 (Pubitemid 44476854)
18. Bennett D. H., Koltzenburg M., Priestley J. V., Shelton D. L., McMahon S. B., Endogenous nerve growth factor regulates the sensitivity of nociceptors in the adult rat European Journal of Neuroscience 1998 10 4 1282 1291 (Pubitemid 28330570)
19. Dmitrieva N., Shelton D., Rice A. S. C., McMahon S. B., The role of nerve growth factor in a model of visceral inflammation Neuroscience 1997 78 2 449 459 (Pubitemid 27170336)
20. Jaggar S. I., Scott H. C. F., Rice A. S. C., Inflammation of the rat urinary bladder is associated with a referred thermal hyperalgesia which is nerve growth factor dependent British Journal of Anaesthesia 1999 83 3 442 448 (Pubitemid 29412699)
21. Kuo H. C., Recent investigations of urinary nerve growth factor as a biomarker for overactive bladder syndrome Korean Journal of Urology 2009 50 9 831 835
22. Chuang Y. C., Fraser M. O., Yu Y., Chancellor M. B., De Groat W. C., Yoshimura N., The role of bladder afferent pathways in bladder hyperactivity induced by the intravesical administration of nerve growth factor Journal of Urology 2001 165 3 975 979 (Pubitemid 32156334)
23. Yoshimura N., Bennett N. E., Hayashi Y., Ogawa T., Nishizawa O., Chancellor M. B., De Groat W. C., Seki S., Bladder overactivity and hyperexcitability of bladder afferent neurons after intrathecal delivery of nerve growth factor in rats Journal of Neuroscience 2006 26 42 10847 10855
24. Lamb K., Gebhart G. F., Bielefeldt K., Increased nerve growth factor expression triggers bladder overactivity Journal of Pain 2004 5 3 150 156 (Pubitemid 38879393)
25. Zvara P., Vizzard M. A., Exogenous overexpression of nerve growth factor in the urinary bladder produces bladder overactivity and altered micturition circuitry in the lumbosacral spinal cord BMC Physiology 2007 7 9 19
26. Frias B., Charrua A., Pinto R., Intrathecal blockade of Trk receptor and neurotrophins sequestration reduces pain and urinary frequency in an animal model of chronic bladder inflammation Neurourology and Urodynamics 2009 28 7 708 708
27. Seki S., Sasaki K., Fraser M. O., Igawa Y., Nishizawa O., Chancellor M. B., De Groat W. C., Yoshimura N., Immunoneutralization of nerve growth factor in the lumbosacral spinal cord reduces bladder hyperreflexia in spinal cord injured rats Journal of Urology 2002 168 5 2269 2274
28. Seki S., Sasaki K., Igawa Y., Nishizawa O., Chancellor M. B., De Groat W. C., Yoshimura N., Suppression of detrusor-sphincter dyssynergia by immunoneutralization of nerve growth factor in lumbosacral spinal cord in spinal cord injured rats Journal of Urology 2004 171 1 478 482 (Pubitemid 37549215)
29. Cruz F., NGF-induced detrusor overactivity is TRPV1 dependent European Urology Supplements 2010 9 2 69
30. Tuttle J. B., Steers W. D., Albo M., Nataluk E., Neural input regulates tissue NGF and growth of the adult rat urinary bladder Journal of the Autonomic Nervous System 1994 49 2 147 158 (Pubitemid 24251643)
31. Lowe E. M., Anand P., Terenghi G., Williams-Chestnut R. E., Sinicropi D. V., Osborne J. L., Increased nerve growth factor levels in the urinary bladder of women with idiopathic sensory urgency and interstitial cystitis British Journal of Urology 1997 79 4 572 577 (Pubitemid 28321098)
32. Dupont M. C., Spitsbergen J. M., Kim K. B., Tuttle J. B., Steers W. D., Histological and neurotrophic changes triggered by varying models of bladder inflammation Journal of Urology 2001 166 3 1111 1118 (Pubitemid 32751054)
33. Vizzard M. A., Neurochemical plasticity and the role of neurotrophic factors in bladder reflex pathways after spinal cord injury Progress in Brain Research 2006 152 97 115
34. Liu H. T., Liu A. B., Chancellor M. B., Kuo H. C., Urinary nerve growth factor level is correlated with the severity of neurological impairment in patients with cerebrovascular accident British Journal of Urology International 2009 104 8 1158 1162
35. Pinto R., Lopes T., Frias B., Silva A., Silva J. A., Silva C. M., Cruz C., Cruz F., Dinis P., Trigonal injection of botulinum toxin A in patients with refractory bladder pain syndrome/interstitial cystitis European Urology 2010 58 3 360 365
36. Steers W. D., Kolbeck S., Creedon D., Tuttle J. B., Nerve growth factor in the urinary bladder of the adult regulates neuronal form and function Journal of Clinical Investigation 1991 88 5 1709 1715
37. Kim J. C., Park E. Y., Seo S. I., Park Y. H., Hwang T. K., Nerve growth factor and prostaglandins in the urine of female patients with overactive bladder Journal of Urology 2006 175 5 1773 1776
38. Yokoyama T., Kumon H., Nagai A., Correlation of urinary nerve growth factor level with pathogenesis of overactive bladder Neurourology and Urodynamics 2008 27 5 417 420 (Pubitemid 351991207)
39. Liu H. T., Kuo H. C., Urinary nerve growth factor level could be a potential biomarker for diagnosis of overactive bladder Journal of Urology 2008 179 6 2270 2274
40. Liu H. T., Chen C. Y., Kuo H. C., Urinary nerve growth factor in women with overactive bladder syndrome British Journal of Urology International 2011 107 5 799 803
41. Chen C. Y., Kuo H. C., Novel urinary biomarkers in the diagnosis and assessment of overactive bladder Incontinence and Pelvic Floor Dysfunction 2009 3 1 20 23
42. Antunes-Lopes T., Urinary neurotrophinspotential biomarkers of overactive bladder Journal of Urology 2011 185 4S 780 781
43. Birder L. A., Wolf-Johnston A., Griffiths D., Resnick N. M., Role of urothelial nerve growth factor in human bladder function Neurourology and Urodynamics 2007 26 3 405 409 (Pubitemid 46717590)
44. Liu H. T., Kuo H. C., Urinary nerve growth factor levels are increased in patients with bladder outlet obstruction with overactive bladder symptoms and reduced after successful medical treatment Urology 2008 72 1 104 108
45. Liu H. T., Chancellor M. B., Kuo H. C., Decrease of urinary nerve growth factor levels after antimuscarinic therapy in patients with overactive bladder British Journal of Urology International 2009 103 12 1668 1672
46. Liu H. T., Chancellor M. B., Kuo H. C., Urinary nerve growth factor levels are elevated in patients with detrusor overactivity and decreased in responders to detrusor botulinum toxin-A injection European Urology 2009 56 4 700 707
47. Pezet S., Malcangio M., McMahon S. B., BDNF: a neuromodulator in nociceptive pathways? Brain Research Reviews 2002 40 1-3 240 249 (Pubitemid 36183173)
48. Kerr B. J., Bradbury E. J., Bennett D. L. H., Trivedi P. M., Dassan P., French J., Shelton D. B., McMahon S. B., Thompson S. W. N., Brain-derived neurotrophic factor modulates nociceptive sensory inputs and NMDA-evoked responses in the rat spinal cord Journal of Neuroscience 1999 19 12 5138 5148 (Pubitemid 29270149)
49. Merighi A., Salio C., Ghirri A., Lossi L., Ferrini F., Betelli C., Bardoni R., BDNF as a pain modulator Progress in Neurobiology 2008 85 3 297 317
50. Michael G. J., Averill S., Nitkunan A., Rattray M., Bennett D. L. H., Van Q., Priestley J. V., Nerve growth factor treatment increases brain-derived neurotrophic factor selectively in TrkA-expressing dorsal root ganglion cells and in their central terminations within the spinal cord Journal of Neuroscience 1997 17 21 8476 8490 (Pubitemid 27461069)
51. Hellard D., Brosenitsch T., Fritzsch B., Katz D. M., Cranial sensory neuron development in the absence of brain-derived neurotrophic factor in BDNF/Bax double null mice Developmental Biology 2004 275 1 34 43 (Pubitemid 39298174)
52. Obata K., Noguchi K., BDNF in sensory neurons and chronic pain Neuroscience Research 2006 55 1 1 10
53. Zhou X. F., Rush R. A., Endogenous brain-derived neurotrophic factor is anterogradely transported in primary sensory neurons Neuroscience 1996 74 4 945 951 (Pubitemid 26313338)
54. Zhao J., Seereeram A., Nassar M. A., Levato A., Pezet S., Hathaway G., Morenilla-Palao C., Stirling C., Fitzgerald M., McMahon S. B., Rios M., Wood J. N., Nociceptor-derived brain-derived neurotrophic factor regulates acute and inflammatory but not neuropathic pain Molecular and Cellular Neuroscience 2006 31 3 539 548 (Pubitemid 43358025)
55. Merighi A., Carmignoto G., Gobbo S., Lossi L., Salio C., Vergnano A. M., Zonta M., Neurotrophins in spinal cord nociceptive pathways Progress in Brain Research 2004 146 291 321 (Pubitemid 37541390)
56. Qiao L. Y., Vizzard M. A., Cystitis-induced upregulation of tyrosine kinase (TrkA, TrkB) receptor expression and phosphorylation in rat micturition pathways Journal of Comparative Neurology 2002 454 2 200 211 (Pubitemid 35265964)
57. Qiao L., Vizzard M. A., Up-regulation of tyrosine kinase (Trka, Trkb) receptor expression and phosphorylation in lumbosacral dorsal root ganglia after chronic spinal cord (T8-T10) injury Journal of Comparative Neurology 2002 449 3 217 230 (Pubitemid 34734281)
58. Qiao L. Y., Vizzard M. A., Spinal cord injury-induced expression of TrkA, TrkB, phosphorylated CREB, and c-Jun in rat lumbosacral dorsal root ganglia Journal of Comparative Neurology 2005 482 2 142 154 (Pubitemid 40066645)
59. Pinto R., Frias B., Allen S., Dawbarn D., McMahon S. B., Cruz F., Cruz C. D., Sequestration of brain derived nerve factor by intravenous delivery of TrkB-Ig2 reduces bladder overactivity and noxious input in animals with chronic cystitis Neuroscience 2010 166 3 907 916
60. Antunes-Lopes T., Urinary levels of brain derived neurotrophic factor (BDNF) in women with overactive bladder (OAB) syndrome correlate with the severity of symptoms European Urology Supplements 2011 10 2 277 278
61. Liu H. T., Kuo H. C., Urinary nerve growth factor levels are elevated in patients with overactive bladder and do not significantly increase with bladder distention Neurourology and Urodynamics 2009 28 1 78 81
62. Hu V. Y., Zvara P., Dattilio A., Redman T. L., Allen S. J., Dawbarn D., Stroemer R. P., Vizzard M. A., Decrease in bladder overactivity with REN1820 in rats with cyclophosphamide induced cystitis Journal of Urology 2005 173 3 1016 1021 (Pubitemid 40239387)
63. Kim J. C., Park E. Y., Seo S. I., Park Y. H., Hwang T. K., Nerve growth factor and prostaglandins in the urine of female patients with overactive bladder Journal of Urology 2006 175 5 1773 1776
64. Yokoyama O., Miwa Y., Oyama N., Aoki Y., Ito H., Akino H., Antimuscarinic drug inhibits detrusor overactivity induced by topical application of prostaglandin E2 to the urethra with a decrease in urethral pressure Journal of Urology 2007 178 5 2208 2212 (Pubitemid 47538577)
65. Su X., Leon L. A., Wu C. W., Morrow D. M., Jaworski J. P., Hieble J. P., Lashinger E. S. R., Jin J., Edwards R. M., Laping N. J., Modulation of bladder function by prostaglandin EP3 receptors in the central nervous system American Journal of Physiology 2008 295 4 F984 F994
66. Liu H. T., Tyagi P., Chancellor M. B., Kuo H. C., Urinary nerve growth factor but not prostaglandin E2 increases in patients with interstitial cystitis/bladder pain syndrome and detrusor overactivity British Journal of Urology International 2010 106 11 1681 1685
67. Wilbraham D., Masuda T., Deacon S., Kuwayama R., Vincent S., Safety, tolerability, and pharmacokinetic of multiple ascending doses of the EP-1 receptor antagonist ONO-8539, a potential new and novel therapy to overactive bladder in healthy young and elderly subjects European Urology Supplements 2010 9 2 250
68. Tyagi P., Barclay D., Zamora R., Yoshimura N., Peters K., Vodovotz Y., Chancellor M., Urine cytokines suggest an inflammatory response in the overactive bladder: a pilot study International Urology and Nephrology 2010 42 3 629 635
69. Compérat E., Reitz A., Delcourt A., Capron F., Denys P., Chartier-Kastler E., Histologic features in the urinary bladder wall affected from neurogenic overactivity-a comparison of inflammation, oedema and fibrosis with and without injection of botulinum toxin type A European Urology 2006 50 5 1058 1064 (Pubitemid 44486475)
70. Apostolidis A., Jacques T. S., Freeman A., Kalsi V., Popat R., Gonzales G., Datta S. N., Ghazi-Noori S., Elneil S., Dasgupta P., Fowler C. J., Histological changes in the urothelium and suburothelium of human overactive bladder following intradetrusor injections of botulinum neurotoxin type A for the treatment of neurogenic or idiopathic detrusor overactivity European Urology 2008 53 6 1245 1253
71. Chuang Y. C., Tyagi V., Liu R. T., Chancellor M. B., Urine and serum C-reactive protein levels as potential biomarkers of lower urinary tract symptoms Urological Science 2010 21 3 132 136
72. Kupelian V., McVary K. T., Barry M. J., Link C. L., Rosen R. C., Aiyer L. P., Mollon P., McKinlay J. B., Association of C-reactive protein (CPR) and lower urinary tract symptoms in men and women: results from boston area community health survey Urology 2009 73 5 950 957