Urinary Nerve Growth Factor Level Could be a Potential Biomarker for Diagnosis of Overactive Bladder

Journal of Urology

Volumn 179, Issue 6, 2008, Pages 2270-2274

  Liu, Hsin Tzu ^a   Kuo, Hann Chorng ^a  

^a TZU CHI UNIVERSITY   (Taiwan)

Author keywords

nerve growth factor; overactive; sensation; urinary bladder; urinary tract

Indexed keywords

CREATINE; NERVE GROWTH FACTOR;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; LOWER URINARY TRACT SYMPTOM; MAJOR CLINICAL STUDY; MALE; OVERACTIVE BLADDER; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN URINE LEVEL; SENSATION; SENSITIVITY AND SPECIFICITY; URINALYSIS;

ADULT; AGED; BIOLOGICAL MARKERS; FEMALE; HUMANS; MALE; MIDDLE AGED; NERVE GROWTH FACTOR; URINARY BLADDER, OVERACTIVE;

EID: 43049112400     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.juro.2008.01.146     Document Type: Article

References (20)

1. Abrams P., Kelleher C.J., Kerr L.A., and Rogers R.G. Overactive bladder significantly affects quality of life. Am J Manag Care 6 (2000) S580
2. Nixon A., Colman S., Sabounjian L., Sandage B., Schwiderski U.E., Staskin D.R., et al. Validated patient reported measure of urinary urgency severity in overactive bladder for use in clinical trials. J Urol 174 (2005) 604
3. Romanzi L.J., Groutz A., Heritz D.M., and Blaivas J.G. Involuntary detrusor contractions: correlation of urodynamic data to clinical categories. Neurourol Urodyn 20 (2001) 249
4. Steers W.D., Kolbeck S., Creedon D., and Tuttle J.B. Nerve growth factor in the urinary bladder of the adult regulates neuronal form and function. J Clin Invest 88 (1991) 1709
5. Tuttle J.B., Steers W.D., Albo M., and Nataluk E. Neural input regulates tissue NGF and growth of the adult urinary bladder. J Auton Nerv Syst 49 (1994) 147
6. Dupont M.C., Spitsberegen J.M., Kim K.B., Tuttle J.B., and Steers W.D. Histological and neurotrophic changes triggered by varying models of bladder inflammation. J Urol 166 (2001) 1111
7. Chung Y.C., Fraser M.O., Yu Y., Chancellor M.B., de Groat W.C., and Yoshimura N. The role of bladder afferent pathways in bladder hyperactivity induced by the intravesical administration of nerve growth factor. J Urol 165 (2001) 975
8. Lowe E.M., Anand P., Terenghi G., Williams-Chestnut R.E., Sinicropi D.V., and Osborne J.L. Increased nerve growth factor levels in the urinary bladder of women with idiopathic sensory urgency and interstitial cystitis. Br J Urol 79 (1997) 572
9. Okragly A.J., Niles A.L., Saban R., Schmidt D., Hoffman R.L., Warner T.F., et al. Elevated tryptase, nerve growth factor, neurotrophin-3 and glial cell line-derived neurotrophic factor levels in the urine of interstitial cystitis and bladder cancer patients. J Urol 161 (1999) 438
10. Murray E., Malley S.E., Qiao L.Y., Hu V.Y., and Vizzard M.A. Cyclophosphamide induced cystitis alters neurotrophin and receptor tyrosine kinase expression in pelvic ganglia and bladder. J Urol 172 (2004) 2434
11. Lommatzsch M., Braun A., Mannsfeldt A., Botchkarev V.A., Botchkareva N.V., Paus R., et al. Abundant production of brain-derived neurotrophic factor by adult visceral epithelia. Implications for paracrine and target-derived Neurotrophic function. Am J Pathol 155 (1999) 1183
12. Lamb K., Gebhart G.F., and Bielefeldt K. Increased nerve growth factor expression triggers bladder overactivity. J Pain 5 (2004) 150
13. Aguayo L.G., and White G. Effects of nerve growth factor on TTX- and capsaicin-sensitivity in adult rat sensory neurons. Brain Res 570 (1992) 61
14. Giannantoni A., Di Stasi S.M., Nardicchi V., Zucchi A., Macchioni L., Bini V., et al. Botulinum-A toxin injections into the detrusor muscle decrease nerve growth factor bladder tissue levels in patients with neurogenic detrusor overactivity. J Urol 175 (2006) 2341
15. Steers W.D., and Tuttle J.B. Mechanisms of diseases: the role of nerve growth factor in the pathophysiology of bladder disorders. Nat Clin Pract Urol 3 (2006) 101
16. Birder L.A., Wolf-Johnston A., Griffiths D., and Resnick N.M. Role of urothelial nerve growth factor in human bladder function. Neurourol Urodyn 26 (2007) 405
17. Kim J.C., and Park E.Y. Nerve growth factor and prostaglandins in the urine of female patients with overactive bladder. J Urol 175 (2006) 1773
18. Digesu G.A., Khullar V., Cardozo L., and Salvatore S. Overactive bladder symptoms: do we need urodynamics?. Neurourol Urodyn 22 (2003) 105
19. Hyman M.J., Groutz A., and Blaivas J.G. Detrusor instability in men: correlation of lower urinary tract symptoms with urodynamic findings. J Urol 166 (2001) 550
20. Hashim H., and Abrams P. Is the bladder a reliable witness for predicting detrusor overactivity?. J Urol 175 (2006) 191