Sequestration of brain derived nerve factor by intravenous delivery of TrkB-Ig2 reduces bladder overactivity and noxious input in animals with chronic cystitis

Neuroscience

Volumn 166, Issue 3, 2010, Pages 907-916

  Pinto, R ^a,b   Frias, B ^a,c   Allen, S ^d   Dawbarn, D ^d   McMahon, S B ^e   Cruz, F ^a,b,c   Cruz, C D ^a,c  

^a UNIVERSITY OF PORTO   (Portugal)

^b HOSPITAL DE SÃO JOÃO   (Portugal)

^c University of Porto   (Portugal)

^d UNIVERSITY OF BRISTOL   (United Kingdom)

^e KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

BDNF; bladder; cystitis; inflammation; intravenous; neurotrophin

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CYCLOPHOSPHAMIDE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN C FOS; SODIUM CHLORIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER CONTRACTION; CELL COUNT; CONTROLLED STUDY; CYSTITIS; CYSTOMETRY; DRUG DOSAGE FORM COMPARISON; DRUG DOSE COMPARISON; FEMALE; HISTOPATHOLOGY; IMMUNOREACTIVITY; MICTURITION REFLEX; NERVE CELL; NOCICEPTIVE STIMULATION; NONHUMAN; OVERACTIVE BLADDER; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD; TISSUE FIXATION; TREATMENT OUTCOME;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CHRONIC DISEASE; CYCLOPHOSPHAMIDE; CYSTITIS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; IMMUNOGLOBULINS; INJECTIONS, INTRAVENOUS; PAIN; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, WISTAR; RECEPTOR, TRKB; RECOMBINANT PROTEINS; REFLEX; SPINAL CORD; URINARY BLADDER; URINARY BLADDER, OVERACTIVE;

EID: 77549086946     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.01.015     Document Type: Article

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