-
1
-
-
33646433989
-
Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis
-
Chen, Y., C.L. Langrish, B. McKenzie, B. Joyce-Shaikh, J.S. Stumhofer, T. McClanahan, W. Blumenschein, T. Churakovsa, J. Low, L. Presta, C.A. Hunter, R.A. Kastelein and D.J. Cua. Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis. J. Clin. Invest. 116: 1317-1326, 2006.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1317-1326
-
-
Chen, Y.1
Langrish, C.L.2
McKenzie, B.3
Joyce-Shaikh, B.4
Stumhofer, J.S.5
McClanahan, T.6
Blumenschein, W.7
Churakovsa, T.8
Low, J.9
Presta, L.10
Hunter, C.A.11
Kastelein, R.A.12
Cua, D.J.13
-
2
-
-
32644470998
-
Matrine improves 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice
-
DOI 10.1016/j.phrs.2005.11.001, PII S1043661805002033
-
Cheng, H., B. Xia, L. Zhang, F. Zhou, Y. X. Zhang, M. Ye, Z. G. Hu, J. Li, J. Li, Z.L. Wang, C. Li and Q. S. Guo. Matrine improves 2,4,6- trinitrobenzene sulfonic acid-induced colitis in mice. Pharmacol. Res. 53: 202-208, 2006. (Pubitemid 43247532)
-
(2006)
Pharmacological Research
, vol.53
, Issue.3
, pp. 202-208
-
-
Cheng, H.1
Xia, B.2
Zhang, L.3
Zhou, F.4
Zhang, Y.-X.5
Ye, M.6
Hu, Z.-G.7
Li, J.8
Li, J.9
Wang, Z.-L.10
Li, C.11
Guo, Q.-S.12
-
3
-
-
77956942049
-
Multiple sclerosis therapies: Molecular mechanisms and future
-
Fontoura, P. and H. Garren, Multiple sclerosis therapies: Molecular mechanisms and future. Results Probl. Cell. Differ. 51: 259-285, 2010.
-
(2010)
Results Probl. Cell. Differ.
, vol.51
, pp. 259-285
-
-
Fontoura, P.1
Garren, H.2
-
5
-
-
27544490377
-
+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
DOI 10.1038/ni1254, PII N1254
-
Harrington, L.E., R.D. Hatton, P.R. Mangan, H. Turner, T.L. Murphy, K.M. Murphy and C.T. Weaver. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat. Immunol. 6: 1123-1132, 2005. (Pubitemid 41541790)
-
(2005)
Nature Immunology
, vol.6
, Issue.11
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
Turner, H.4
Murphy, T.L.5
Murphy, K.M.6
Weaver, C.T.7
-
6
-
-
67649383126
-
Th17 cells in MS and experimental autoimmune encephalomyelitis
-
Hofstetter, H., R. Gold and H.P. Hartung. Th17 cells in MS and experimental autoimmune encephalomyelitis. Int. MS J. 16: 12-18, 2009.
-
(2009)
Int. MS J.
, vol.16
, pp. 12-18
-
-
Hofstetter, H.1
Gold, R.2
Hartung, H.P.3
-
7
-
-
79958721221
-
Th17 cell, the new player of neuroinflammatory process in multiple sclerosis
-
Jadidi-Niaragh, F. and A. Mirshafiey. Th17 cell, the new player of neuroinflammatory process in multiple sclerosis. Scand. J. Immunol. 74(1): 1-13, 2011.
-
(2011)
Scand. J. Immunol.
, vol.74
, Issue.1
, pp. 1-13
-
-
Jadidi-Niaragh, F.1
Mirshafiey, A.2
-
8
-
-
46949104323
-
IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition
-
DOI 10.1084/jem.20080159
-
Kroenke, M.A., T.J. Carlson, A.V. Andjelkovic and B. M. Segal. IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition. J. Exp. Med. 205: 1535-1541, 2008. (Pubitemid 351962016)
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.7
, pp. 1535-1541
-
-
Kroenke, M.A.1
Carlson, T.J.2
Andjelkovic, A.V.3
Segal, B.M.4
-
9
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
DOI 10.1084/jem.20041257
-
Langrish, C.L., Y. Chen, W.M. Blumenschein, J. Mattson, B. Basham, J.D. Sedgwick, T. McClanahan, R.A. Kastelein and D.J. Cua. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J. Exp. Med. 201: 233-240, 2005. (Pubitemid 40189432)
-
(2005)
Journal of Experimental Medicine
, vol.201
, Issue.2
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
McClanahan, T.7
Kastelein, R.A.8
Cua, D.J.9
-
10
-
-
75149160094
-
Matrine induces cell anergy in human Jurkat T cells through modulation of mitogen-activated protein kinases and nuclear factor of activated T-cells signaling with concomitant up-regulation of anergy-associated genes expression
-
Li, T., V.K. Wong, X.Q. Yi, Y.F. Wong, H. Zhou and L. Liu. Matrine induces cell anergy in human Jurkat T cells through modulation of mitogen-activated protein kinases and nuclear factor of activated T-cells signaling with concomitant up-regulation of anergy-associated genes expression. Biol. Pharm. Bull. 33: 40-46, 2010.
-
(2010)
Biol. Pharm. Bull.
, vol.33
, pp. 40-46
-
-
Li, T.1
Wong, V.K.2
Yi, X.Q.3
Wong, Y.F.4
Zhou, H.5
Liu, L.6
-
12
-
-
9744244198
-
Capsule oxymatrine in treatment of hepatic fibrosis due to chronic viral hepatitis: A randomized, double blind, placebo-controlled, multicenter clinical study
-
Mao, Y.M., M.D. Zeng, L.G. Lu, M.B. Wan, C.Z. Li, C.W. Chen, Q.C. Fu, J.Y. Wang, W.M. She, X. Cai, J. Ye, X.Q. Zhou, H. Wang, S.M. Wu, M.F. Tang, J.S. Zhu, W.X. Chen and H.Q. Zhang. Capsule oxymatrine in treatment of hepatic fibrosis due to chronic viral hepatitis: A randomized, double blind, placebo-controlled, multicenter clinical study. World J. Gastroenterol. 10: 3269-3273, 2004. (Pubitemid 39585463)
-
(2004)
World Journal of Gastroenterology
, vol.10
, Issue.22
, pp. 3269-3273
-
-
Mao, Y.-M.1
Zeng, M.-D.2
Lu, L.-G.3
Wan, M.-B.4
Li, C.-Z.5
Chen, C.-W.6
Fu, Q.-C.7
Wang, J.-Y.8
She, W.-M.9
Cai, X.10
Ye, J.11
Zhou, X.-Q.12
Wang, H.13
Wu, S.-M.14
Tang, M.-F.15
Zhu, J.-S.16
Chen, W.-X.17
Zhang, H.-Q.18
-
13
-
-
39449110445
-
The link between IL-23 and Th17 cell-mediated immune pathologies
-
DOI 10.1016/j.smim.2007.10.012, PII S1044532307000875
-
McGeachy, M.J. and D.J. Cua. The link between IL-23 and Th17 cell-mediated immune pathologies. Semin. Immunol. 19: 372-376, 2007. (Pubitemid 351274049)
-
(2007)
Seminars in Immunology
, vol.19
, Issue.6
, pp. 372-376
-
-
McGeachy, M.J.1
Cua, D.J.2
-
14
-
-
33747886404
-
A new focal EAE model of cortical demyelination: Multiple sclerosis-like lesions with rapid resolution of inflammation and extensive remyelination
-
DOI 10.1093/brain/awl135
-
Merkler, D., T. Ernsting, M. Kerschensteiner, W. Bruck and C. Stadelmann. A new focal EAE model of cortical demyelination: Multiple sclerosis-like lesions with rapid resolution of inflammation and extensive remyelination. Brain 129: 1972-1983, 2006. (Pubitemid 44289063)
-
(2006)
Brain
, vol.129
, Issue.8
, pp. 1972-1983
-
-
Merkler, D.1
Ernsting, T.2
Kerschensteiner, M.3
Bruck, W.4
Stadelmann, C.5
-
15
-
-
30744452481
-
The effect of Nigella sativa oil against experimental allergic encephalomyelitis via nitric oxide and other oxidative stress parameters
-
Ozugurlu, F., S. Sahin, N. Idiz, O. Akyol, A. Ilhan, R. Yigitoglu and B. Isik. The effect of Nigella sativa oil against experimental allergic encephalomyelitis via nitric oxide and other oxidative stress parameters. Cell. Mol. Biol. 51: 337-342, 2005. (Pubitemid 43093386)
-
(2005)
Cellular and Molecular Biology
, vol.51
, Issue.3
, pp. 337-342
-
-
Ozugurlu, F.1
Sahin, S.2
Idiz, N.3
Akyol, O.4
Ilhan, A.5
Yigitoglu, R.6
Isik, B.7
-
16
-
-
0029965137
-
A few autoreactive cells in an autoimmune infiltrate control a vast population of nonspecific cells: A tale of smart bombs and the infantry
-
DOI 10.1073/pnas.93.6.2253
-
Steinman, L. A few autoreactive cells in an autoimmune infiltrate control a vast population of nonspecific cells: A tale of smart bombs and the infantry. Proc. Natl. Acad. Sci. USA 93: 2253-2256, 1996. (Pubitemid 26104336)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.6
, pp. 2253-2256
-
-
Steinman, L.1
-
17
-
-
0037313578
-
Interleukin-12 and the regulation of innate resistance and adaptive immunity
-
DOI 10.1038/nri1001
-
Trinchieri, G. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 3: 133-146, 2003. (Pubitemid 37328691)
-
(2003)
Nature Reviews Immunology
, vol.3
, Issue.2
, pp. 133-146
-
-
Trinchieri, G.1
-
18
-
-
55249119122
-
Repeated 0.5-Gy gamma irradiation attenuates experimental autoimmune encephalomyelitis with up-regulation of regulatory T cells and suppression of IL-17 production
-
Tsukimoto, M., H. Nakatsukasa, K. Sugawara, K. Yamashita and S. Kojima. Repeated 0.5-Gy gamma irradiation attenuates experimental autoimmune encephalomyelitis with up-regulation of regulatory T cells and suppression of IL-17 production. Radiat. Res. 170: 429-436, 2008.
-
(2008)
Radiat. Res.
, vol.170
, pp. 429-436
-
-
Tsukimoto, M.1
Nakatsukasa, H.2
Sugawara, K.3
Yamashita, K.4
Kojima, S.5
-
19
-
-
84862833485
-
Toxicity of matrine in Kunming mice]. [Article in Chinese]
-
Wang, X.Y., L. Liang, J.L. Chang, N.H. Yang and Z.G. Li. [Toxicity of matrine in Kunming mice]. [Article in Chinese] Nan Fang Yi Ke Da Xue Xue Bao 30: 2154-2155, 2010.
-
(2010)
Nan Fang Yi Ke Da Xue Xue Bao
, vol.30
, pp. 2154-2155
-
-
Wang, X.Y.1
Liang, L.2
Chang, J.L.3
Yang, N.H.4
Li, Z.G.5
-
20
-
-
77957866376
-
Regulation of antitumor immune responses by the IL-12 family cytokines, IL-12, IL-23, and IL-27
-
pii 832454. Epub 2010 Sep 14
-
Xu, M., I. Mizoguchi, N. Morishima, Y. Chiba, J. Mizuguchi and T. Yoshimoto. Regulation of antitumor immune responses by the IL-12 family cytokines, IL-12, IL-23, and IL-27. Clin. Dev. Immunol. 2010: Pii: 832454. Epub 2010 Sep 14.
-
Clin. Dev. Immunol.
, vol.2010
-
-
Xu, M.1
Mizoguchi, I.2
Morishima, N.3
Chiba, Y.4
Mizuguchi, J.5
Yoshimoto, T.6
-
21
-
-
72849120756
-
Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis
-
Yang, J., Z. Jiang, D.C. Fitzgerald, C. Ma, S. Yu, H. Li, Z. Zhao, Y. Li, B. Ciric, M. Curtis, A. Rostami and G.X. Zhang. Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis. J. Clin. Invest. 119: 3678-3691, 2009.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3678-3691
-
-
Yang, J.1
Jiang, Z.2
Fitzgerald, D.C.3
Ma, C.4
Yu, S.5
Li, H.6
Zhao, Z.7
Li, Y.8
Ciric, B.9
Curtis, M.10
Rostami, A.11
Zhang, G.X.12
-
22
-
-
77953281486
-
Pathological analysis of heroin spongiform leukoencephalopathy
-
Yin, J., S.Y. Pan, L. Zhou, T.M. Lu, Y.F. Luo and B.X. Lu. Pathological analysis of heroin spongiform leukoencephalopathy. Nan Fang Yi Ke Da Xue Xue Bao 27: 881-883, 2007.
-
(2007)
Nan Fang Yi Ke Da Xue Xue Bao
, vol.27
, pp. 881-883
-
-
Yin, J.1
Pan, S.Y.2
Zhou, L.3
Lu, T.M.4
Luo, Y.F.5
Lu, B.X.6
-
23
-
-
0037442020
-
Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-β2-deficient mice: IL-12 responsiveness is not required in the pathogenesis of inflammatory demyelination in the central nervous system
-
Zhang, G.X., B. Gran, S. Yu, J. Li, I. Siglienti, X. Chen, M. Kamoun and A. Rostami. Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-beta 2-deficient mice: IL-12 responsiveness is not required in the pathogenesis of inflammatory demyelination in the central nervous system. J. Immunol. 170: 2153-2160, 2003. (Pubitemid 36197439)
-
(2003)
Journal of Immunology
, vol.170
, Issue.4
, pp. 2153-2160
-
-
Zhang, G.-X.1
Gran, B.2
Yu, S.3
Li, J.4
Siglienti, I.5
Chen, X.6
Kamoun, M.7
Rostami, A.8
-
24
-
-
55249100081
-
Sophocarpine and matrine inhibit the production of TNF-alpha and IL-6 in murine macrophages and prevent cachexia-related symptoms induced by colon26 adenocarcinoma in mice
-
Zhang, Y., S. Wang, Y. Li, Z. Xiao, Z. Hu and J. Zhang. Sophocarpine and matrine inhibit the production of TNF-alpha and IL-6 in murine macrophages and prevent cachexia-related symptoms induced by colon26 adenocarcinoma in mice. Int. Immunopharmacol. 8: 1767-1772, 2008.
-
(2008)
Int. Immunopharmacol.
, vol.8
, pp. 1767-1772
-
-
Zhang, Y.1
Wang, S.2
Li, Y.3
Xiao, Z.4
Hu, Z.5
Zhang, J.6
-
25
-
-
77951672060
-
Total alkaloids of Sophora alopecuroides increases the expression of CD4+ CD25+ Tregs and IL-10 in rats with experimental colitis
-
Zhou, Y., H. Wang, L. Liang, W.C. Zhao, Y. Chen and H. Z. Deng. Total alkaloids of Sophora alopecuroides increases the expression of CD4+ CD25+ Tregs and IL-10 in rats with experimental colitis. Am. J. Chin. Med. 38: 265-277, 2010.
-
(2010)
Am. J. Chin. Med.
, vol.38
, Issue.265-277
-
-
Zhou, Y.1
Wang, H.2
Liang, L.3
Zhao, W.C.4
Chen, Y.5
Deng, H.Z.6
|