Activity Prediction of Some Nontested Anticancer Compounds Using GA-Based PLS Regression Models

Chemical Biology and Drug Design

Volumn 78, Issue 4, 2011, Pages 587-595

  Nandi, Sisir ^a   Bagchi, Manish C ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

Genetic algorithm; Molecular field analysis; Murine tumors; Partial least squares; Pyrido pyrimidine derivatives; Three dimensional quantitative structure activity relationship

Indexed keywords

6 (2,6 DICHLOROPHENYL)PYRIDO[2,3 D]PYRIMIDIN 7(8H)ONE DERIVATIVE; ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; COMPARATIVE MOLECULAR FIELD ANALYSIS; CONTROLLED STUDY; DRUG SCREENING; ENZYME INHIBITION; GENETIC ALGORITHM; PARTIAL LEAST SQUARES REGRESSION; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ALGORITHMS; ANIMALS; ANTINEOPLASTIC AGENTS; DRUG DESIGN; HUMANS; LEAST-SQUARES ANALYSIS; MICE; MODELS, BIOLOGICAL; MODELS, MOLECULAR; NEOPLASMS; PYRIMIDINES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

MURINAE;

EID: 80052639727     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2011.01177.x     Document Type: Article

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