2d QSAR modeling and preliminary database searching for dopamine transporter inhibitors using genetic algorithm variable selection of Molconn Z descriptors

Journal of Medicinal Chemistry

Volumn 43, Issue 22, 2000, Pages 4151-4159

  Hoffman, B T ^a   Kopajtic, T ^a   Katz, J L ^a   Newman, A H ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE; DOPAMINE TRANSPORTER; DOPAMINE TRANSPORTER INHIBITOR; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ALGORITHM; ARTICLE; COMPUTER PROGRAM; DATA BASE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REGRESSION ANALYSIS;

ALGORITHMS; BINDING, COMPETITIVE; CARRIER PROTEINS; DATABASES, FACTUAL; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; LIGANDS; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MODELS, MOLECULAR; NERVE TISSUE PROTEINS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RADIOLIGAND ASSAY; REPRODUCIBILITY OF RESULTS; SOFTWARE;

EID: 0034597582     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990472s     Document Type: Article

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