Cancer risk in Jewish BRCA1 and BRCA2 mutation carriers: Effects of oral contraceptive use and parental origin of mutation

Breast Cancer Research and Treatment

Volumn 129, Issue 2, 2011, Pages 557-563

  Bernholtz, Shiri ^a   Laitman, Yael ^a   Kaufman, Bella ^b,c   Paluch Shimon, Shani ^b   Friedman, Eitan ^a,c  

^a GERTNER INSTITUTE FOR EPIDEMIOLOGY AND HEALTH POLICY RESEARCH   (Israel)

^b SHEBA MEDICAL CENTER   (Israel)

^c TEL AVIV UNIVERSITY   (Israel)

Author keywords

BRCA1 BRCA2 germline mutations; Breast cancer; OC use; Parental origin of mutation

Indexed keywords

ORAL CONTRACEPTIVE AGENT;

ADULT; ARTICLE; BREAST CANCER; BREAST FEEDING; CANCER RISK; CONTROLLED STUDY; ETHNIC GROUP; FEMALE; GENE MUTATION; GENOTYPE; HUMAN; ISRAELI; JEW; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MENARCHE; ONCOGENE; OVARY CANCER; PARITY; PATIENT COUNSELING; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

ADULT; AGED; AGED, 80 AND OVER; BRCA1 PROTEIN; BRCA2 PROTEIN; BREAST NEOPLASMS; CHI-SQUARE DISTRIBUTION; CONTRACEPTIVES, ORAL; DNA MUTATIONAL ANALYSIS; FEMALE; GENES, P16; GENETIC PREDISPOSITION TO DISEASE; GERM-LINE MUTATION; HEREDITY; HETEROZYGOTE; HUMANS; ISRAEL; JEWS; KAPLAN-MEIER ESTIMATE; LOGISTIC MODELS; MIDDLE AGED; ODDS RATIO; OVARIAN NEOPLASMS; PEDIGREE; PHENOTYPE; RISK ASSESSMENT; RISK FACTORS; SURVIVAL RATE; YOUNG ADULT;

EID: 80052611746     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-011-1509-z     Document Type: Article

References (33)

1. A Jemal R Siegel J Xu E Ward 2010 Cancer statistics, 2010 CA Cancer J Clin 60 5 277 300 20610543 10.3322/caac.20073
2. D Ford DF Easton M Stratton S Narod D Goldgar P Devilee DT Bishop B Weber G Lenoir J Chang-Claude H Sobol MD Teare J Struewing A Arason S Scherneck J Peto TR Rebbeck P Tonin S Neuhausen R Barkardottir J Eyfjord H Lynch BA Ponder SA Gayther M Zelada-Hedman 1998 Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium Am J Hum Genet 62 676 689 9497246 10.1086/301749 1:CAS:528: DyaK1MXlvFeh (Pubitemid 28164626)
3. D Abeliovich L Kaduri I Lerer N Weinberg G Amir M Sagi J Zlotogora N Heching T Peretz 1997 The founder mutations 185delAG and 5382insC in BRCA1 and 6174delT in BRCA2 appear in 60% of ovarian cancer and 30% of early-onset breast cancer patients among Ashkenazi women Am J Hum Genet 60 505 514 9042909 1:CAS:528:DyaK2sXhvFGjtLY%3D (Pubitemid 27097598)
4. CI Szabo MC King 1997 Population genetics of BRCA1 and BRCA2 Am J Hum Genet 60 1013 1020 9150148 1:STN:280:DyaK2s3psVeqsA%3D%3D (Pubitemid 27194085)
5. A Antoniou PD Pharoah S Narod HA Risch JE Eyfjord JL Hopper N Loman H Olsson O Johannsson A Borg B Pasini P Radice S Manoukian DM Eccles N Tang E Olah H Anton-Culver E Warner J Lubinski J Gronwald B Gorski H Tulinius S Thorlacius H Eerola H Nevanlinna K Syrjäkoski OP Kallioniemi D Thompson C Evans J Peto F Lalloo DG Evans DF Easton 2003 Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: a combined analysis of 22 studies Am J Hum Genet 72 5 1117 1130 12677558 10.1086/375033 1:CAS:528:DC%2BD3sXjslagtbg%3D (Pubitemid 36530000)
6. S Simchoni E Friedman B Kaufman R Gershoni-Baruch A Orr-Urtreger I Kedar-Barnes R Shiri-Sverdlov E Dagan S Tsabari M Shohat R Catane MC King A Lahad E Levy-Lahad 2006 Familial clustering of site-specific cancer risks associated with BRCA1 and BRCA2 mutations in the Ashkenazi Jewish population Proc Natl Acad Sci USA 103 10 3770 3774 16537453 10.1073/pnas.0511301103 1:CAS:528:DC%2BD28XivFWis7g%3D (Pubitemid 43376630)
7. SA Narod 2006 Modifiers of risk of hereditary breast cancer Oncogene 25 43 5832 5836 16998497 10.1038/sj.onc.1209870 1:CAS:528:DC%2BD28XhtVSgurvK (Pubitemid 44453438)
8. E Levy-Lahad E Friedman 2007 Cancer risks among BRCA1 and BRCA2 mutation carriers Br J Cancer 96 1 11 15 17213823 10.1038/sj.bjc.6603535 1:CAS:528:DC%2BD2sXis1Kntw%3D%3D (Pubitemid 46094632)
9. Collaborative Group on Hormonal Factors in Breast Cancer 1996 Breast cancer and hormonal contraceptives: collaborative reanalysis of individual data on 53 297 women with breast cancer and 100 239 women without breast cancer from 54 epidemiological studies Lancet 347 9017 1713 1727 10.1016/S0140-6736(96) 90806-5 (Pubitemid 26187550)
10. DM Grabrick LC Hartmann JR Cerhan RA Vierkant TM Therneau CM Vachon JE Olson FJ Couch KE Anderson VS Pankratz TA Sellers 2000 Risk of breast cancer with oral contraceptive use in women with a family history of breast cancer JAMA 284 1791 1798 11025831 10.1001/jama.284.14.1791 1:STN:280: DC%2BD3cvnvVaitw%3D%3D
11. G Ursin BE Henderson RW Haile MC Pike N Zhou A Diep L Bernstein 1997 Does oral contraceptive use increase the risk of breast cancer in women with BRCA1/BRCA2 mutations more than in other women? Cancer Res 57 3678 3681 9288771 1:CAS:528:DyaK2sXlvFentrs%3D (Pubitemid 27381207)
12. SA Narod 2001 Hormonal prevention of hereditary breast cancer Ann NY Acad Sci 952 36 43 11795442 10.1111/j.1749-6632.2001.tb02726.x 1:CAS:528: DC%2BD38XnsFWmsw%3D%3D (Pubitemid 34060008)
13. R Shiri-Sverdlov P Oefner L Green RG Baruch T Wagner A Kruglikova S Haitchick RM Hofstra MZ Papa I Mulder S Rizel RB Bar Sade E Dagan Z Abdeen B Goldman E Friedman 2000 Mutational analysis of BRCA1 and BRCA2 in Ashkenazi and non-Ashkenazi Jewish women with familial breast cancer Hum Mutat 6 491 501 10.1002/1098-1004(200012)16:6<491::AID-HUMU6>3.0.CO;2-J (Pubitemid 32001298)
14. EM Rohlf WG Learning KJ Friedman FJ Couch BL Weber LM Silverman 1997 Direct detection of mutations in the breast and ovarian cancer susceptibility gene BRCA1 by PCR-mediated site-directed mutagenesis Clin Chem 43 24 29
15. A Schüler S Weber M Neuhäuser C Jurklies T Lehnert H Heimann G Rudolph KH Jöckel N Bornfeld DR Lohmann 2005 Age at diagnosis of isolated unilateral retinoblastoma does not distinguish patients with and without a constitutional RB1 gene mutation but is influenced by a parent-of-origin effect Eur J Cance 41 5 735 740 10.1016/j.ejca.2004.12.022 (Pubitemid 40342557)
16. IM Morison LM Ellis LR Teague AE Reeve 2002 Preferential loss of maternal 9p alleles in childhood acute lymphoblastic leukemia Blood 99 1 375 377 11756195 10.1182/blood.V99.1.375 1:CAS:528:DC%2BD38XivF2ntA%3D%3D (Pubitemid 34533007)
17. L Kluwe V Mautner DM Parry LB Jacoby M Baser J Gusella K Davis D Stavrou M MacCollin 2000 The parental origin of new mutations in neurofibromatosis 2 Neurogenetics 3 1 17 24 11085592 10.1007/s100480000088 1:CAS:528: DC%2BD3MXjvVOisLk%3D
18. S Aretz S Uhlhaas R Caspari E Mangold C Pagenstecher P Propping W Friedl 2004 Frequency and parental origin of de novo APC mutations in familial adenomatous polyposis Eur J Hum Genet 12 1 52 58 14523376 10.1038/sj.ejhg. 5201088 1:CAS:528:DC%2BD2cXls1Cr (Pubitemid 38180970)
19. G Mantovani S Bondioni AG Lania S Corbetta L de Sanctis M Cappa E Di Battista P Chanson P Beck-Peccoz A Spada 2004 Parental origin of Gsalpha mutations in the McCune-Albright syndrome and in isolated endocrine tumors J Clin Endocrinol Metab 89 6 3007 3009 15181091 10.1210/jc.2004-0194 1:CAS:528:DC%2BD2cXmtlKjsLs%3D (Pubitemid 38766401)
20. SD Merajver TS Frank J Xu TM Pham KA Calzone P Bennett-Baker J Chamberlain J Boyd JE Garber FS Collins 1995 Germline BRCA1 mutations and loss of the wild-type allele in tumors from families with early onset breast and ovarian cancer Clin Cancer Res 1 5 539 544 9816013 1:CAS:528:DyaK2sXht1CqtLY%3D
21. C La Vecchia A Altieri S Franceschi A Tavani 2001 Oral contraceptives and cancer: an update Drug Saf 24 741 754 11676302 10.2165/00002018-200124100-00003 1:CAS:528:DC%2BD3MXntlansL4%3D (Pubitemid 32848353)
22. ME Gaffield KR Culwell A Ravi 2009 Oral contraceptives and family history of breast cancer Contraception 80 4 372 380 19751860 10.1016/j.contraception. 2009.04.010 1:CAS:528:DC%2BD1MXhtFajtrvJ
23. D Cibula A Gompel AO Mueck C La Vecchia PC Hannaford SO Skouby M Zikan L Dusek 2010 Hormonal contraception and risk of cancer Hum Reprod Update 16 6 631 650 20543200 10.1093/humupd/dmq022 1:CAS:528:DC%2BC3cXhtlShu7%2FL
24. P Pasanisi G Hédelin J Berrino J Chang-Claude S Hermann M Steel N Haites J Hart R Peled L Gafà L Leggio A Traina R Amodio M Primic-Zakelj V Zadnik T Veidebaum M Tekkel F Berrino 2009 Oral contraceptive use and BRCA penetrance: a case-only study Cancer Epidemiol Biomarkers Prev 18 7 2107 2113 19549808 10.1158/1055-9965.EPI-09-0024 1:CAS:528:DC%2BD1MXosFWjs7w%3D
25. H Jernström N Loman OT Johannsson A Borg H Olsson 2005 Impact of teenage oral contraceptive use in a population-based series of early-onset breast cancer cases who have undergone BRCA mutation testing Eur J Cancer 41 15 2312 2320 16118051 10.1016/j.ejca.2005.03.035 (Pubitemid 41415608)
26. G Ursin RK Ross J Sullivan-Halley R Hanisch B Henderson L Bernstein 1998 Use of oral contraceptives and risk of breast cancer in young women Breast Cancer Res Treat 50 175 184 9822222 10.1023/A:1006037823178 1:CAS:528: DyaK1cXntlCrtbc%3D (Pubitemid 28454396)
27. K Heimdal E Skovlund P Moller 2002 Oral contraceptives and risk of familial breast cancer Cancer Detect Prev 26 23 27 12088199 10.1016/S0361- 090X(02)00004-1 1:CAS:528:DC%2BD38XlsFOmtLk%3D (Pubitemid 36087178)
28. PA Marchbanks JA McDonald HG Wilson SG Folger MG Mandel JR Daling L Bernstein KE Malone G Ursin BL Strom SA Norman PA Wingo RT Burkman JA Berlin MS Simon R Spirtas LK Weiss 2002 Oral contraceptives and the risk of breast cancer N Engl J Med 346 2025 2032 12087137 10.1056/NEJMoa013202 1:CAS:528: DC%2BD38XkvFartLc%3D (Pubitemid 34680593)
29. L Kaduri M Gibs A Hubert M Sagi N Heching I Lerer B Uziely N Weinberg D Abeliovich T Peretz 1999 Genetic testing of breast and ovarian cancer patients: clinical characteristics and hormonal risk modifiers Eur J Obstet Gynecol Reprod Biol 85 75 80 10428326 10.1016/S0301-2115(98)00286-3 1:CAS:528: DyaK1MXjt1KksLo%3D (Pubitemid 29248787)
30. SA Narod MP Dubé J Klijn J Lubinski HT Lynch P Ghadirian D Provencher K Heimdal P Moller M Robson K Offit C Isaacs B Weber E Friedman R Gershoni-Baruch G Rennert B Pasini T Wagner M Daly JE Garber SL Neuhausen P Ainsworth H Olsson G Evans M Osborne F Couch WD Foulkes E Warner C Kim-Sing O Olopade N Tung HM Saal J Weitzel S Merajver M Gauthier-Villars H Jernstrom P Sun JS Brunet 2002 Oral contraceptives and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers J Natl Cancer Inst 94 1773 1779 12464649 1:CAS:528:DC%2BD38XptlOitLo%3D (Pubitemid 36004353)
31. D Thompson D Easton Breast Cancer Linkage Consortium 2001 Variation in cancer risks, by mutation position, in BRCA2 mutation carriers Am J Hum Genet 68 2 410 419 11170890 10.1086/318181 1:CAS:528:DC%2BD3MXhtl2lsLs%3D (Pubitemid 32147810)
32. HA Risch JR McLaughlin DE Cole B Rosen L Bradley E Kwan E Jack DJ Vesprini G Kuperstein JL Abrahamson I Fan B Wong SA Narod 2001 Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer Am J Hum Genet 68 3 700 710 11179017 10.1086/318787 1:CAS:528:DC%2BD3MXit1aksr8%3D (Pubitemid 32203724)
33. J Lubinski CM Phelan P Ghadirian HT Lynch J Garber B Weber N Tung D Horsman C Isaacs AN Monteiro P Sun SA Narod 2004 Cancer variation associated with the position of the mutation in the BRCA2 gene Fam Cancer 23 1 1 10 (Pubitemid 40655347)