Synthesis of a quinazoline derivative: A new α 1- adrenoceptor ligand for conjugation to quantum dots to study α 1-adrenoceptors in living cells

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 19, 2011, Pages 5905-5909

  Zhou, Guoheng ^a   Wang, Lei ^a   Ma, Yudao ^a   Wang, Liping ^a   Zhang, Youyi ^b   Jiang, Wei ^a  

^a SHANDONG UNIVERSITY   (China)

^b PEKING UNIVERSITY THIRD HOSPITAL   (China)

Author keywords

1 Adrenoceptor; Adrenoceptor antagonist; Fluorescent probe; Quantum dot; Quinazoline

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; FLUORESCENT DYE; ION CHANNEL; MEMBRANE RECEPTOR; QUANTUM DOT; QUINAZOLINE DERIVATIVE;

ARTICLE; BINDING ASSAY; BIOLOGICAL ACTIVITY; CONJUGATION; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN TISSUE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR DYNAMICS; RECEPTOR BINDING;

ADRENERGIC ALPHA-1 RECEPTOR ANTAGONISTS; BIOLOGICAL ASSAY; BIOTIN; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; HEK293 CELLS; HUMANS; LIGANDS; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; PIPERAZINES; POLYETHYLENE GLYCOLS; PRAZOSIN; PROTEIN BINDING; QUANTUM DOTS; QUINAZOLINES; RECEPTORS, ADRENERGIC, ALPHA-1;

EID: 80052585810     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.07.122     Document Type: Article

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