Solid-phase synthesis and pharmacological evaluation of novel nucleoside-tethered dinuclear platinum(II) complexes

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 19, 2011, Pages 5835-5838

  D'Errico, Stefano ^a   Oliviero, Giorgia ^a   Piccialli, Vincenzo ^a   Amato, Jussara ^a   Borbone, Nicola ^a   D'Atri, Valentina ^a   D'Alessio, Francesca ^b   Noto, Rosa Di ^a,b   Ruffo, Francesco ^a   Salvatore, Francesco ^b,c   Piccialli, Gennaro ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b CEINGE BIOTECNOLOGIE AVANZATE   (Italy)

^c IRCCS SDN   (Italy)

Author keywords

Anti tumor compounds; Dinuclear platinum complexes; Nucleosides; Solid phase synthesis

Indexed keywords

CISPLATIN; PLATINUM COMPLEX;

ARTICLE; CANCER CELL CULTURE; DRUG CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; SOLID PHASE SYNTHESIS;

AGED; ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DIAMINES; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HELA CELLS; HUMANS; INHIBITORY CONCENTRATION 50; INOSINE; MOLECULAR STRUCTURE; NUCLEOSIDES; PLATINUM; SOLID-PHASE SYNTHESIS TECHNIQUES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 80052582315     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.07.104     Document Type: Article

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