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Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 19, 2011, Pages 5928-5933

Identification of potent c-Src inhibitors strongly affecting the proliferation of human neuroblastoma cells

(14) Radi, Marco a Brullo, Chiara b Crespan, Emmanuele c Tintori, Cristina a Musumeci, Francesca b Biava, Mariangela d Schenone, Silvia b Dreassi, Elena a Zamperini, Claudio a Maga, Giovanni c Pagano, Dafne c Angelucci, Adriano e Bologna, Mauro e Botta, Maurizio a,f

a UNIVERSITY OF SIENA (Italy)

b UNIVERSITY OF GENOA (Italy)

c CNR (Italy)

d SAPIENZA UNIVERSITY OF ROME (Italy)

e UNIVERSITY OF L'AQUILA (Italy)

f Temple University (United States)

Author keywords

Bcr Abl; c Src; Kinase; Neuroblastoma; Pyrazolo 3,4 d pyrimidines

Indexed keywords

BCR ABL PROTEIN; PROTEIN TYROSINE KINASE INHIBITOR;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG POTENCY; DRUG SPECIFICITY; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; CELL ADHESION; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; MOLECULAR TARGETED THERAPY; NEUROBLASTOMA; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-ABL; PYRAZOLES; PYRIMIDINES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SRC-FAMILY KINASES; SUBSTRATE SPECIFICITY;

EID: 80052577975 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.07.079 Document Type: Article

Times cited : (46)

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