4-Anilino-7-pyridyl-3-quinolinecarbonitriles as Src kinase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 17, 2009, Pages 5071-5074

  Zhang, Nan ^a   Wu, Biqi ^a   Boschelli, Diane H ^a   Golas, Jennifer M ^a   Boschelli, Frank ^a  

^a WYETH RESEARCH   (United States)

Author keywords

4 Anilino 7 pyridyl 3 quinolinecarbonitriles; Src kinase inhibitors

Indexed keywords

3 QUINOLINECARBONITRILE; 4 ANILINO 7 PYRIDYL 3 QUINOLINECARBONITRILE DERIVATIVE; 4 METHYL 1 PIPERAZINE DERIVATIVE; BOSUTINIB; CYANIDE; DASATINIB; PROTEIN TYROSINE KINASE; PYRIDINE DERIVATIVE; SRC KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL ASSAY; DRUG POTENCY; DRUG SCREENING; ENZYME ASSAY; ENZYME INHIBITION; HUMAN; IN VIVO STUDY; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; XENOGRAFT;

AMINOQUINOLINES; ANILINE COMPOUNDS; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; HUMANS; MICE; MICE, NUDE; PROTEIN KINASE INHIBITORS; QUINOLINES; RATS; SRC-FAMILY KINASES; STRUCTURE-ACTIVITY RELATIONSHIP; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 68349154362     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.07.043     Document Type: Article

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