Adhesion molecules (ICAM-1 and VCAM-1) and diabetic retinopathy in type 2 diabetes

Journal of Molecular Histology

Volumn 39, Issue 2, 2008, Pages 243-249

  Khalfaoui, Taoufik ^a   Lizard, Gérard ^b   Ouertani Meddeb, Amel ^a  

^a CHARLES NICOLLE HOSPITAL   (Tunisia)

^b UNIVERSITÉ DE BOURGOGNE   (France)

Author keywords

Adhesion molecules; Conjunctiva; Diabetes; Diabetic retinopathy; ICAM 1; Immunohistochemistry; VCAM 1

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; PEROXIDASE; VASCULAR CELL ADHESION MOLECULE 1;

ADULT; AGED; ARTICLE; CATARACT EXTRACTION; COMPARATIVE STUDY; CONJUNCTIVA; CONTROLLED STUDY; DIABETIC PATIENT; DIABETIC RETINOPATHY; ENDOTHELIUM CELL; EPITHELIUM CELL; EYE EXAMINATION; EYE FUNDUS; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOASSAY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; MEDIATOR; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA FLUORESCEIN ANGIOGRAPHY; STATISTICAL SIGNIFICANCE; STROMA CELL; UPREGULATION; VASCULAR ENDOTHELIUM;

AGED; AGED, 80 AND OVER; CONJUNCTIVA; DIABETES MELLITUS, TYPE 2; DIABETIC RETINOPATHY; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INTERCELLULAR ADHESION MOLECULE-1; MALE; MIDDLE AGED; VASCULAR CELL ADHESION MOLECULE-1;

EID: 41049095627     PISSN: 15672379     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10735-007-9159-5     Document Type: Article

References (32)

1. Abu-El-Asrar AM, Geboes K, Al-Kharashi S, Tabbara KF, Missotten L, Desmet V (1997) Adhesion molecules in vernal keratoconjunctivitis. Br J Ophthalmol 81:1099-1106
2. Abu-El-Asrar AM, Dralands L, Missoten L, Al-Jadaan IA, Geboes K (2004) Expression of apoptosis markers in the retinas of human subjects with diabetes. Invest Ophthalmol Vis 45:2760-2766
3. Adamis AP (2002) Is diabetic retinopathy an inflammatory disease? Br J Ophthalmol 86:363-365
4. Altannavch TS, Roubalova K, Kucera P, Andel M (2004) Effect of high glucose concentrations on expression of ELAM-1, VCAM-1 and ICAM-1 in HUVEC with and without cytokine activation. Physiol Res 53:77-82
5. Archer DB (1999) Diabetic retinopathy: some cellular, molecular and therapeutic considerations. Eye 13:497-523
6. Barile GR, Chang SS, Park LS, Reppucci VS, Schiff WM, Schmidt AM (1999) Soluble cellular adhesion molecules in proliferative vitreoretinopathy and proliferative diabetic retinopathy. Curr Eye Res 19:219-227
7. Chakrabarti S, Cukiernik M, Hileeto D, Evans T, Chen S (2000) Role of vasoactive factors in the pathogenesis of early changes in diabetic retinopathy. Diabetes Metab Res Rev 16:393-407
8. Chen W, Jump DB, Grant MB, Esselman WJ, Busik JV (2003) Dyslipidemia, but not hyperglycemia, induces inflammatory adhesion molecules in human retinal vascular endothelial cells. Invest Ophthalmol Vis Sci 44:5016-5022
9. Cheung AKH, Fung MKL, Lo ACY, Lam TTL, So KF, Chung SSM, Chung SK (2005) Aldose reductase deficiency prevents diabetes-induced blood-retinal barrier breakdown, apoptosis, and glial reactivation in the retina of db/db mice. Diabetes 54:3119-3125
10. Ciulla TA, Harris A, Latkany P, Piper HC, Arend O, Garzozi H, Martin B (2002) Ocular perfusion abnormalities in diabetes. Acta Ophthalmol Scand 80:468-477
11. Fong DS, Atello L, Gardner TW, King JL, Blankenship G, Cavallerano JD, Ferris FL, Klein R (2003) Diabetic retinopathy. Diabetes Care 26:226-229
12. Joussen AM, Poulaki V, Mitsiades N, Kirchhof B, Koisumi K, Dohmen S, Adamis AP (2002a) Nonsteroidal anti-inflammatory drugs prevent early diabetic retinopathy via TNF-α suppression. FASEB J 16:438-440
13. Joussen AM, Poulaki V, Tsujikawa A, Qin W, Quam T, Xu Q, Moromizato Y, Bursell SE, Wiegand SJ, Rudge J, Loffe E, Yancopoulos GD, Adamis AP (2002b) Suppression of diabetic retinopathy with angiopoitin-1. Am J Pathol 160:1683-1693
14. Joussen AM, Poulaki V, Le ML (2004) A central role for inflammation in the pathogenesis of diabetic retinopathy. FASEB J 10:1-17
15. Kowluru RA, Odenbach S (2004) Role of interleukin-1beta in the pathogenesis of diabetic retinopathy. Br J Ophthalmol 88:1343-1347
16. Kria L, Khalfaoui T, Mkannez G, Beltaief O, Anane R, Errais K, Tounsi L, Zhioua R, Jilani SB, Ouertani AM (2005) Immunohistochemical study of vascular endothelial growth factor (VEGF), tumor suppressor protein (p53) and intercellular adhesion molecule (ICAM-1) in the conjunctiva of diabetic patients. J Mol Histol 36:381-390
17. Limb GA, Hickman-Casey J, Hollifield RD, Chignell AH (1999) Vascular adhesion molecules in vitreous from eyes with proliferative diabetic retinopathy. Invest Ophthalmol Vis Sci 40:2453-2457
18. Lloyd PA (1997) Clinical implications of vascular growth factors in proliferative retinopathies. Curr Opin Ophthalmol 8:19-31
19. Manaviat MR, Afkhami M, Shoja MR (2004) Retinopathy and microalbumineria in type II diabetic patients. BMC Ophthalmol 4:1471-1475
20. McLeod DS, Lefer DJ, Merges C, Lutty GA (1995) Enhanced expression of intracellular adhesion molecule-1 and P-selectin in the diabetic human retina and choroid. Am J Pathol 147:642-653
21. Meleth AD, Agron E, Chan CC, Reed GF, Arora K, Byrnes G, Csaky KG, Ferris FL, Chew EY (2005) Serum inflammatory markers in diabetic retinopathy. Invest Ophthalmol Vis Sci 46:4295-4301
22. Platts KE, Benson MT, Rennie IG, Sharrard RM, Rees RC (1995) Cytokine modulation of adhesion molecule expression on human retinal pigment epithelial cells. Invest Ophtalmol Vis Sci 36:2262-2269
23. Sampson MJ, Davies IR, Brown JC, Ivory K, Hughes DA (2002) Monocyte and neutrophil adhesion molecule expression during acute hyperglycemia and after antioxidant treatment type 2 diabetes and control patients. Arterioscler Thromb Vasc Biol 22:1187-1193
24. Sangwan VS, Merchant A, De la Maza MS, Foster S (1998) Leucocyte adhesion molecule expression in scleritis. Arch Ophthalmol 116:1476-1480
25. Santos KG, Schneider JR, Souta KEP, Roisenberg I (2005) Prevalence of retinopathy in caucasian type II diabetic patients from the south of Brazil and relationship with clinical and metabolic factors. Braz J Med Biol Res 38:221-225
26. Stitt AW, Curtis TM (2005) Advanced glycation and retinal pathology during diabetes. Pharmacol Rep 57:156-168
27. Takahashi M, Ikeda U, Masuyama J, Funayama H, Kano S, Shimada K (1996) Nitric oxide attenuates adhesion molecule expression in human endothelial cells. Cytokine 8:817-821
28. Tapp RJ, Shaw JE, Harper CA, De Courten MP, Blakau B, MacCarty DJ, Taylor HR, Welborn TA, Zimmet PZ (2003) The prevalence of and factors associated with diabetic retinopathy in the Australian population. Diabetes Care 26:1731-1737
29. Varin R, Mulder P, Tamion F, Richard V, Henry JP, Lallemand F, Lerebours G, Thuillez C (2000) Improvement of endothelial function by chronic angiotensin-coverting enzyme inhibition in heart failure: role of nitric oxide, prostanoids, oxidant stress, and bradykinin. Circulation 102:351-356
30. Vorkauf M, Duncker G, Nolle B, Sterry W (1993) Adhesion molecules in normal human conjunctiva. An immunohistological study using monoclonal antibodies. Graefes Arch Clin Exp Ophthalmol 231:323-330
31. Wilkinson-Berka JL (2004) Vasoactive factors and diabetic retinopathy: vascular endothelial growth factor, cycoloxygenase-2 and nitric oxide. Curr Pharm Des 10:3331-3348
32. Yam JC, Kwok AKh (2007) Update on the treatment of diabetic retinopathy. Hong Kong Med J 13:46-60