Adeno-associated virus serotype 9-mediated overexpression of extracellular superoxide dismutase improves recovery from surgical hind-limb ischemia in BALB/c mice

Journal of Vascular Surgery

Volumn 54, Issue 3, 2011, Pages 810-818

  Saqib, Amina ^a   Prasad, Konkal Matt R ^b   Katwal, Arabindra B ^a   Sanders, John M ^a   Lye, R John ^a   French, Brent A ^a,b   Annex, Brian H ^a,b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b University of Virginia   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD31 ANTIGEN; CYCLIC GMP; EXTRACELLULAR SUPEROXIDE DISMUTASE; LUCIFERASE; PARVOVIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ADENO ASSOCIATED VIRUS TYPE 9; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CAPILLARY DENSITY; CELL NUCLEUS; CONTROLLED STUDY; CONVALESCENCE; CYTOMEGALOVIRUS; GENE OVEREXPRESSION; HINDLIMB; IMMUNOHISTOCHEMISTRY; LASER DOPPLER FLOWMETRY; LIMB ISCHEMIA; LIMB PERFUSION; MALE; MOUSE; NECROSIS; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SKELETAL MUSCLE; UPREGULATION; VIRAL GENE THERAPY; VIRUS CAPSID; WESTERN BLOTTING;

ANIMALS; ANTIGENS, CD31; APOPTOSIS; BLOTTING, WESTERN; CAPILLARIES; CYCLIC GMP; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; GENE THERAPY; GENETIC VECTORS; HINDLIMB; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INJECTIONS, INTRAMUSCULAR; ISCHEMIA; LASER-DOPPLER FLOWMETRY; LUCIFERASES, FIREFLY; MALE; MICE; MICE, INBRED BALB C; MUSCLE, SKELETAL; NECROSIS; NEOVASCULARIZATION, PHYSIOLOGIC; RECOMBINANT FUSION PROTEINS; RECOVERY OF FUNCTION; REGIONAL BLOOD FLOW; SUPEROXIDE DISMUTASE; TIME FACTORS;

EID: 80052530589     PISSN: 07415214     EISSN: 10976809     Source Type: Journal    
DOI: 10.1016/j.jvs.2011.03.278     Document Type: Article

References (39)

1. K. Ouriel Peripheral arterial disease Lancet 358 2001 1257 1264 (Pubitemid 33010855)
2. B. Balkau, M. Vray, and E. Eschwege Epidemiology of peripheral arterial disease J Cardiovasc Pharmacol 23 Suppl 3 1994 S8 S16
3. P. Carmeliet Mechanisms of angiogenesis and arteriogenesis Nat Med 6 2000 389 395 (Pubitemid 30208155)
4. M.T. Kuhlmann, R. Klocke, and S. Nikol Therapeutic angiogenesis for peripheral artery disease: cytokine therapy Vasa 36 2007 253 260 (Pubitemid 350260419)
5. H. Lawall, P. Bramlage, and B. Amann Stem cell and progenitor cell therapy in peripheral artery disease A critical appraisal Thromb Haemost 103 2010 696 709
6. R. Gupta, J. Tongers, and D.W. Losordo Human studies of angiogenic gene therapy Circ Res 105 2009 724 736 Review
7. O. Jung, S.L. Marklund, H. Geiger, T. Pedrazzini, R. Busse, and R.P. Brandes Extracellular superoxide dismutase is a major determinant of nitric oxide bioavailability: in vivo and ex vivo evidence from ecSOD-deficient mice Circ Res 93 2003 622 629 (Pubitemid 37222158)
8. K.A. Brown, Y. Chu, D.D. Lund, D.D. Heistad, and F.M. Faraci Gene transfer of extracellular superoxide dismutase protects against vascular dysfunction with aging Am J Physiol Heart Circ Physiol 290 2006 H2600 H2605
9. Ha Won Kim, A. Lin, R.E. Guldberg, M. Ushio-Fukai, and T. Fukai Essential role of extracellular SOD in reparative neovascularization induced by hind limb ischemia Circ Researc 101 2007 409
10. K.-M.R. Prasad, Y. Xu, R.J. Beyers, M.H. Vandsburger, R.H. Harris, and F.H. Epstein Cardiac-specific over expression of EcSOD from an AAV9-pseudotyped vector increases capillary density and reduces infarct size Cicrulation 120 2009 S592 S593
11. K. Fukino, M. Sata, Y. Seko, Y. Hirata, and R. Nagai Genetic background influences therapeutic effectiveness of VEGF Biochem Biophys Res Commun 310 2003 143 147 (Pubitemid 37162774)
12. M.G. Kaplitt, P. Leone, R.J. Samulski, X. Xiao, D.W. Pfaff, and K.L. O'Malley Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain Nat Genet 8 1994 148 154 (Pubitemid 24308362)
13. K.M. Prasad, Y. Xu, Z. Yang, S.T. Acton, and B.A. French Robust cardiomyocyte-specific gene expression following systemic injection of AAV: in vivo gene delivery follows a Poisson distribution Gene Ther 2011 18 2011 43 52
14. K.M. Prasad, Z. Yang, D. Bleich, and J.L. Nadler Adeno-associated virus vector mediated gene transfer to pancreatic beta cells Gene Ther 7 2000 1553 1561
15. G.-P. Gao, M.R. Alvira, L. Wang, R. Calcedo, J. Johnston, and J.M. Wilson Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy Proc Natl Ac Sc U S A 99 2002 11854 11859 (Pubitemid 34994488)
16. G. Gao, L.H. Vandenberghe, M.R. Alvira, Y. Lu, R. Calcedo, and X. Zhou Clades of adeno-associated viruses are widely disseminated in human tissues J Virol 78 2004 6381 6388 (Pubitemid 38715936)
17. M.U. Ried, A. Girod, K. Leike, H. Bning, and M. Hallek Adeno-associated virus capsids displaying immunoglobulin-binding domains permit antibody-mediated vector retargeting to specific cell surface receptors J Virol 76 2002 4559 4566 (Pubitemid 34309591)
18. K.-M.R. Prasad, Y. Xu, Z. Yang, M.-C. Toufektsian, S.S. Berr, and B.A. French Topoisomerase inhibition accelerates gene expression after adeno-associated virus-mediated gene transfer to the mammalian heart Mole Ther 15 2007 764 771 (Pubitemid 46431997)
19. Q. Dai, J. Huang, B. Klitzman, C. Dong, P.J. Goldschmidt-Clermont, and K.L. March Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hind limb ischemia Circulation 110 2004 2467 2475 (Pubitemid 39407355)
20. D. Xie, Y. Li, E.A. Reed, S.I. Odronic, and C.D. Kontos An engineered vascular endothelial growth factor-activating transcription factor induces therapeutic angiogenesis in ApoE knockout mice with hind limb ischemia J Vasc Surg 44 2006 166 175 (Pubitemid 43975290)
21. A.O. Dokun, S. Keum, S. Hazarika, Y. Li, G.M. Lamonte, and F. Wheeler A quantitative trait locus (LSq-1) on mouse chromosome 7 is linked to the absence of tissue loss after surgical hindlimb ischemia Circulation 117 2008 1207 1215 (Pubitemid 351544070)
22. A. Aicher, C. Heeschen, S. Feil, F. Hofmann, M.E. Mendelsohn, and R. Feil cGMP-dependent protein kinase I is crucial for angiogenesis and postnatal vasculogenesis PLoS ONE 4 2009 e4879
23. H. Layman, M.G. Spiga, T. Brooks, S. Pham, K.A. Webster, and F.M. Andreopoulos The effect of the controlled release of basic fibroblast growth factor from ionic gelatin-based hydrogels on angiogenesis in a murine critical limb ischemic model Biomaterials 28 2007 2646 2654 (Pubitemid 46367212)
24. L. Li, H. Okada, G. Takemura, M. Esaki, H. Kobayashi, and H. Kanamori Sustained release of erythropoietin using biodegradable gelatin hydrogel microspheres persistently improves lower leg ischemia J Am Coll Cardiol 23 2009 2378 2388
25. S. Mori, T. Sawada, and K. Kubota Asialoerythropoietin is a strong modulator of angiogenesis by bone-marrow cells J Invest Surg 20 2007 357 362
26. T. Urano, Y. Ito, M. Akao, T. Sawa, K. Miyata, and M. Tabata Angiopoietin-related growth factor enhances blood flow via activation of the ERK1/2-eNOS-NO pathway in a mouse hind-limb ischemia model Arterioscler Thromb Vasc Biol 28 2008 827 834 (Pubitemid 351544095)
27. T.T. Rissanen, I. Vajanto, and S. Yl-Herttuala Gene therapy for therapeutic angiogenesis in critically ischemic lower limb - on the way to the clinic Eur J Clin Invest 31 2001 651 666 (Pubitemid 32756613)
28. Y. Tsurumi, S. Takeshita, D. Chen, M. Kearney, S.T. Rossow, and J. Passeri Direct intramuscular gene transfer of naked DNA encoding vascular endothelial growth factor augments collateral development and tissue perfusion Circulation 15 1996 3281 3290 (Pubitemid 26427500)
29. J. Nalbantoglu, N. Larochelle, E. Wolf, G. Karpati, H. Lochmuller, and P.C. Holland Muscle-specific overexpression of the adenovirus primary receptor CAR overcomes low efficiency of gene transfer to mature skeletal muscle J Virol 75 2001 4276 4282 (Pubitemid 32410140)
30. T.T. Rissanen, J.E. Markkanen, M. Gruchala, T. Heikura, A. Puranen, and M.I. Kettunen VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses Circ Res 30 2003 1098 1106 (Pubitemid 36665855)
31. M. Shimpoa, U. Ikedaa, Y. Maedaa, M. Takahashia, H. Miyashita, and H. Mizukami AAV-mediated VEGF gene transfer into skeletal muscle stimulates angiogenesis and improves blood flow in a rat hind limb ischemia model Cardiovasc Res 53 2002 993 1001 (Pubitemid 34261037)
32. D.S. Chang, Su Hua, G.L. Tang, L.S. Brevetti, R. Sarkar, and Rong Wang Adeno-associated viral vector-mediated gene transfer of VEGF normalizes skeletal muscle oxygen tension and induces arteriogenesis in ischemic rat hindlimb Mol Ther 7 2003 44 51 (Pubitemid 36312923)
33. F. Chen, Z. Tan, C.Y. Dong, X. Chen, and S.F. Guo Adeno-associated virus vectors simultaneously encoding VEGF and angiopoietin-1 enhances neovascularization in ischemic rabbit hind-limbs Acta Pharmacol Sin 28 2007 493 502 (Pubitemid 46496081)
34. R.J. Hajjar, K. Zsebo, L. Deckelbaum, C. Thompson, J. Rudy, and A. Yaroshinsky Design of a phase 1/2 trial of intracoronary administration of AAV1/SERCA2a in patients with heart failure J Card Fail 14 2008 355 367 (Pubitemid 351756538)
35. C. Mueller, and T.R. Flotte Clinical gene therapy using recombinant adeno-associated virus vectors Gene Ther 15 2008 858 863 (Pubitemid 351712619)
36. J. Oshikawa, N. Urao, H.W. Kim, N. Kaplan, and M. Razvi Extracellular SOD-derived H2O2 promotes VEGF signaling in caveolae/lipid rafts and post-ischemic angiogenesis in mice PLoS ONE 5 2010 e10189
37. B. Guérette, P.A. Moisset, C. Huard, F. Tardif, C. Gravel, and J.P. Tremblay Inflammatory damage following first-generation replication-defective adenovirus controlled by anti-LFA-1 J Leukoc Biol 61 1997 533 538 (Pubitemid 27219849)
38. M. Sahara, M. Sata, T. Morita, T. Nakajima, Y. Hirata, and R. Nagai A phosphodiesterase-5 inhibitor vardenafil enhances angiogenesis through a protein kinase G-dependent hypoxia-inducible factor-1/vascular endothelial growth factor pathway Arterioscler Thromb Vasc Biol 30 2010 1315 1324
39. 2 homeostasis by hypoxia-inducible factor 1 Annu Rev Cell Dev Biol 15 1999 551 578 (Pubitemid 32250386)