Sustained Release of Erythropoietin Using Biodegradable Gelatin Hydrogel Microspheres Persistently Improves Lower Leg Ischemia

Journal of the American College of Cardiology

Volumn 53, Issue 25, 2009, Pages 2378-2388

  Li, Longhu ^a   Okada, Hideshi ^a   Takemura, Genzou ^a   Esaki, Masayasu ^a   Kobayashi, Hiroyuki ^a   Kanamori, Hiromitsu ^a   Kawamura, Itta ^a   Maruyama, Rumi ^a   Fujiwara, Takako ^b   Fujiwara, Hisayoshi ^a   Tabata, Yasuhiko ^c   Minatoguchi, Shinya ^a  

^a GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYOTO WOMEN'S UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

angiogenesis; erythropoietin; ischemia; vascular disease

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; ERYTHROPOIETIN RECEPTOR; GELATIN; GELATINASE A; HEMOGLOBIN; INTERLEUKIN 1BETA; MICROSPHERE; PROTEIN KINASE; RECOMBINANT ERYTHROPOIETIN; SODIUM CHLORIDE; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOLE; ARTICLE; BIODEGRADABILITY; BLOOD FLOW; CAPILLARY DENSITY; CONTROLLED STUDY; DENSITY; ENDOTHELIUM; ENZYME ACTIVATION; FEMORAL ARTERY; HEMOGLOBIN BLOOD LEVEL; HINDLIMB; HYDROGEL; LEG ISCHEMIA; LEG MUSCLE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; STEM CELL; SUSTAINED DRUG RELEASE;

ADULT STEM CELLS; ANGIOGENESIS INDUCING AGENTS; ANIMALS; CELLS, CULTURED; DELAYED-ACTION PREPARATIONS; ENDOTHELIAL CELLS; ERYTHROPOIETIN, RECOMBINANT; HYDROGELS; ISCHEMIA; LOWER EXTREMITY; MALE; MICE; MICE, INBRED BALB C; MICROSPHERES; MYOCYTES, SMOOTH MUSCLE; NEOVASCULARIZATION, PHYSIOLOGIC; PERIPHERAL VASCULAR DISEASES; RECEPTORS, ERYTHROPOIETIN; REGIONAL BLOOD FLOW;

EID: 66949176881     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2009.02.056     Document Type: Article

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