Elevated transcription of the p53 gene in early S-phase leads to a rapid DNA-damage response during S-phase of the cell cycle

Apoptosis

Volumn 16, Issue 9, 2011, Pages 950-958

  Takahashi, Paula ^a,b   Polson, Amanda ^a   Reisman, David ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Apoptosis; Checkpoints; DNA damage; p53; S phase

Indexed keywords

CAMPTOTHECIN; CASPASE 3; CASPASE 7; MESSENGER RNA; PROTEIN BAX; PROTEIN P21; PROTEIN P53;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL CYCLE S PHASE; CELL STRAIN 3T3; DNA DAMAGE; DNA FRAGMENTATION; DNA RESPONSIVE ELEMENT; ENZYME ACTIVITY; GENETIC TRANSCRIPTION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CAMPTOTHECIN; CASPASE 3; CASPASE 7; CHROMATIN IMMUNOPRECIPITATION; DNA DAMAGE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, P53; MICE; RNA, MESSENGER; S PHASE; SWISS 3T3 CELLS; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 80052499395     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-011-0623-z     Document Type: Article

References (33)

1. HF Horn KH Vousden 2007 Coping with stress: multiple ways to activate p53 Oncogene 26 1306 1316 17322916 10.1038/sj.onc.1210263 1:CAS:528: DC%2BD2sXitVKhsLY%3D (Pubitemid 46328472)
2. KH Vousden C Prives 2009 Blinded by the light: the growing complexity of p53 Cell 137 413 431 19410540 10.1016/j.cell.2009.04.037 1:CAS:528: DC%2BD1MXlvFams74%3D
3. ML Agarwal A Agarwal WR Taylor O Chernova Y Sharma GR Stark 1998 A p53- dependent S-phase checkpoint helps to protect cells from DNA damage in response to starvation for pyrimidine nucleotides Proc Natl Acad Sci USA 95 14775 14780 9843965 10.1073/pnas.95.25.14775 1:CAS:528:DyaK1cXotVGmtb8%3D (Pubitemid 29003706)
4. DP Lane 1992 Cancer. p53, guardian of the genome Nature 358 15 16 1614522 10.1038/358015a0 1:STN:280:DyaK38zhtVGmtA%3D%3D
5. LD Attardi T Jacks 1999 The role of p53 in tumour suppression: lessons from mouse models Cell Mol Life Sci 55 48 63 10065151 10.1007/s000180050269 1:CAS:528:DyaK1MXhtV2lsLo%3D (Pubitemid 29077854)
6. NC Reich AJ Levine 1984 Growth regulation of a cellular tumour antigen, p53, in nontransformed cells Nature 308 199 201 6366574 10.1038/308199a0 1:CAS:528:DyaL2cXhsFCqtbo%3D (Pubitemid 14129563)
7. J Mosner T Mummenbrauer C Bauer G Sczakiel F Grosse W Deppert 1995 Negative feedback regulation of wild-type p53 biosynthesis EMBO J 14 4442 4449 7556087 1:CAS:528:DyaK2MXovVektrw%3D
8. M Oren V Rotter 1999 Introduction: p53-the first twenty years Cell Mol Life Sci 5 9 11 10.1007/s000180050265 (Pubitemid 29077850)
9. Y Barak T Juven R Haffner M Oren 1993 mdm2 expression is induced by wild type p53 activity EMBO J 12 461 468 8440237 1:CAS:528:DyaK3sXhtFyhsrk%3D (Pubitemid 23073692)
10. S Fang JP Jensen RL Ludwig KH Vousden AM Weissman 2000 Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53 J Biol Chem 275 8945 8951 10722742 10.1074/jbc.275.12.8945 1:CAS:528:DC%2BD3cXit1emtrs%3D (Pubitemid 30180252)
11. KS Yee KH Vousden 2005 Complicating the complexity of p53 Carcinogenesis 26 1317 1322 15888490 10.1093/carcin/bgi122 1:CAS:528:DC%2BD2MXmsV2itr0%3D (Pubitemid 41430092)
12. MB Kastan O Onyekwere D Sidransky B Vogelstein RW Craig 1991 Participation of p53 protein in the cellular response to DNA damage Cancer Res 51 6304 6311 1933891 1:CAS:528:DyaK38XhvFSltg%3D%3D
13. D Menendez A Inga MA Resnick 2009 The expanding universe of p53 targets Nat Rev Cancer 10 724 737 10.1038/nrc2730
14. KG Wolter YT Hsu CL Smith A Nechushtan XG Xi RJ Youle 1997 Movement of Bax from the cytosol to mitochondria during apoptosis J Cell Biol 139 1281 1292 9382873 10.1083/jcb.139.5.1281 1:CAS:528:DyaK2sXnvFeqsLg%3D (Pubitemid 27523214)
15. RJ Youle A Strasser 2008 The BCL-2 protein family: opposing activities that mediate cell death Nat Rev Mol Cell Biol 9 47 59 18097445 10.1038/nrm2308 1:CAS:528:DC%2BD2sXhsVKrsrrP
16. V Gottifredi K McKinney MV Poyurovsky C Prives 2004 Decreased p21 levels are required for efficient restart of DNA synthesis after S phase block J Biol Chem 279 5802 5810 14597617 10.1074/jbc.M310373200 1:CAS:528: DC%2BD2cXhtFCjsrc%3D (Pubitemid 38220611)
17. F Janus N Albrechtsen I Dornreiter L Wiesmüller F Grosse W Deppert 1999 The dual role model for p53 in maintaining genomic integrity Cell Mol Life Sci 55 12 27 10065148 10.1007/s000180050266 1:CAS:528:DyaK1MXhtV2lsL8%3D (Pubitemid 29077851)
18. WR Taylor GR Stark 2001 Regulation of the G2/M transition by p53 Oncogene 20 1803 1815 11313928 10.1038/sj.onc.1204252 1:CAS:528:DC%2BD3MXivFKhtr4%3D (Pubitemid 32458690)
19. JC Reed JD Alpers PC Nowell RG Hoover 1986 Sequential expression of protooncogenes during lectin-stimulated mitogenesis of normal human lymphocytes Proc Natl Acad Sci USA 83 3982 3986 3012540 10.1073/pnas.83.11.3982 1:CAS:528:DyaL28XktlKksr0%3D (Pubitemid 16062406)
20. D Ginsberg M Oren M Yaniv J Piette 1990 Protein-binding elements in the promoter region of the mouse p53 gene Oncogene 5 1285 1290 2216454 1:CAS:528:DyaK3MXls1Kiug%3D%3D
21. K Boggs D Reisman 2006 Increased p53 transcription prior to DNA synthesis is regulated through a novel regulatory element within the p53 promoter Oncogene 25 555 565 16158047 1:CAS:528:DC%2BD28XnsV2quw%3D%3D (Pubitemid 43164466)
22. SB Horwitz CK Chang AP Grollman 1971 Studies on camptothecin: I. Effects on nucleic acid and protein synthesis Mol Pharmacol 7 632 644 4948241 1:CAS:528:DyaE38XotFSjtA%3D%3D
23. YH Hsiang R Hertzberg S Hecht LF Liu 1985 Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I J Biol Chem 260 14873 14878 2997227 1:CAS:528:DyaL2MXlsFemt7c%3D (Pubitemid 16211028)
24. Y Mei C Xie W Xie X Tian M Li M Wu 2007 Noxa/Mcl-1 balance regulates susceptibility of cells to camptothecin-induced apoptosis Neoplasia 9 871 881 17971907 10.1593/neo.07589 1:CAS:528:DC%2BD2sXhtl2rtr3I (Pubitemid 47623427)
25. R Fink K Fink 1962 Utilization of radiocarbon from thymidine and other precursors of ribonucleic acid in Neurospora crassa J Biol Chem 237 2289 2290 13892978 1:CAS:528:DyaF38XktlyntLg%3D
26. S Strano E Munarriz M Rossi L Castagnoli Y Shaul A Sacchi, et al. 2001 Physical interaction with Yes-associated protein enhances p73 transcriptional activity J Biol Chem 276 15164 15173 11278685 10.1074/jbc.M010484200 1:CAS:528:DC%2BD3MXjs1Orsbc%3D
27. K Boggs D Reisman 2007 The transcription factor C/EBP is essential for cell cycle regulation of the p53 gene J. Biol. Chem. 282 7982 7990 17244625 10.1074/jbc.M611675200 1:CAS:528:DC%2BD2sXis1Kgtrs%3D (Pubitemid 47093547)
28. A Polson P Takahashi D Reisman 2010 Chromatin Immunoprecipitation (ChIP) Analysis Demonstrates Coordinated Binding of Two Transcription Factors to the Promoter of the p53 Tumor Suppressor Gene Cell Biol Int 34 883 891 20446924 10.1042/CBI20090401 1:CAS:528:DC%2BC3cXhtVWqtbbI
29. H Offer, et al. 2001 p53 modulates base excision repair activity in a cell cycle-specific manner after genotoxic stress Cancer Res 61 88 96 11196204 1:CAS:528:DC%2BD3MXlsl2muw%3D%3D (Pubitemid 32095705)
30. S Jin AJ Levine 2001 The p53 functional circuit J Cell Sci 114 4139 4140 11739646 1:CAS:528:DC%2BD3MXptlKrt7o%3D (Pubitemid 33138651)
31. V Firlej B Bocquet X Desbiens Y de Launoit A Chotteau-Lelièvre 2005 Pea3 transcription factor cooperates with USF-1 in regulation of the murine bax transcription without binding to an Ets-binding site J Biol Chem 280 887 898 15466854 10.1074/jbc.M408017200 1:CAS:528:DC%2BD2MXitFGjuw%3D%3D
32. V Gottifredi S Shieh Y Taya C Prives 2001 p53 accumulates but is functionally impaired when DNA synthesis is blocked Proc Natl Acad Sci USA 98 1036 1041 11158590 10.1073/pnas.021282898 1:CAS:528:DC%2BD3MXht1SmsLs%3D (Pubitemid 32121182)
33. XP Zhang F Lui W Wang 2010 Coordination between cell cycle progression and cell fate decision by the p53 and E2F1 pathways in response to DNA damage J Biol Chem 285 31571 31580 20685653 10.1074/jbc.M110.134650 1:CAS:528: DC%2BC3cXht1aqt77J