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Volumn 52, Issue 10, 2011, Pages 7027-7037

Mitochondria-Targeted Peptide MTP-131 alleviates mitochondrial dysfunction and oxidative damage in human trabecular meshwork cells

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; CASPASE 3; CYTOCHROME C; HYDROGEN PEROXIDE; LACTATE DEHYDROGENASE; MTP 131; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

EID: 80052492687     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.11-7524     Document Type: Article
Times cited : (37)

References (42)
  • 1
    • 64249131959 scopus 로고    scopus 로고
    • The trabecular meshwork outflow pathways: Structural and functional aspects
    • Tamm ER. The trabecular meshwork outflow pathways: structural and functional aspects. Exp Eye Res. 2009;88:648-655.
    • (2009) Exp Eye Res , vol.88 , pp. 648-655
    • Tamm, E.R.1
  • 2
    • 20544468453 scopus 로고    scopus 로고
    • Morphological changes in glaucomatous eyes and the role of TGFbeta2 for the pathogenesis of the disease
    • Lutjen-Drecoll E. Morphological changes in glaucomatous eyes and the role of TGFbeta2 for the pathogenesis of the disease. Exp Eye Res. 2005;81:1-4.
    • (2005) Exp Eye Res , vol.81 , pp. 1-4
    • Lutjen-Drecoll, E.1
  • 4
    • 2442643730 scopus 로고    scopus 로고
    • Primary open-angle glaucoma
    • Weinreb RN, Khaw PT. Primary open-angle glaucoma. Lancet. 2004;363:1711-1720.
    • (2004) Lancet , vol.363 , pp. 1711-1720
    • Weinreb, R.N.1    Khaw, P.T.2
  • 6
    • 33846109820 scopus 로고    scopus 로고
    • Genetic etiologies of glaucoma
    • Wiggs JL. Genetic etiologies of glaucoma. Arch Ophthalmol. 2007; 125:30-37.
    • (2007) Arch Ophthalmol , vol.125 , pp. 30-37
    • Wiggs, J.L.1
  • 7
    • 16844379509 scopus 로고    scopus 로고
    • Oxidative DNA damage in the human trabecular meshwork: Clinical correlation in patients with primary open-angle glaucoma
    • Sacca SC, Pascotto A, Camicione P, Capris P, Izzotti A. Oxidative DNA damage in the human trabecular meshwork: clinical correlation in patients with primary open-angle glaucoma. Arch Ophthalmol. 2005;123:458-463.
    • (2005) Arch Ophthalmol , vol.123 , pp. 458-463
    • Sacca, S.C.1    Pascotto, A.2    Camicione, P.3    Capris, P.4    Izzotti, A.5
  • 8
    • 0042594473 scopus 로고    scopus 로고
    • Proteasome inhibition by chronic oxidative stress in human trabecular meshwork cells
    • Caballero M, Liton PB, Epstein DL, Gonzalez P. Proteasome inhibition by chronic oxidative stress in human trabecular meshwork cells. Biochem Biophys Res Commun. 2003;308:346-352.
    • (2003) Biochem Biophys Res Commun , vol.308 , pp. 346-352
    • Caballero, M.1    Liton, P.B.2    Epstein, D.L.3    Gonzalez, P.4
  • 9
    • 58149126021 scopus 로고    scopus 로고
    • Stress response of the trabecular meshwork
    • Liton PB, Gonzalez P. Stress response of the trabecular meshwork. J Glaucoma. 2008;17:378-385.
    • (2008) J Glaucoma , vol.17 , pp. 378-385
    • Liton, P.B.1    Gonzalez, P.2
  • 10
    • 0037938809 scopus 로고    scopus 로고
    • Oxidative deoxyribonucleic acid damage in the eyes of glaucoma patients
    • Izzotti A, Sacca SC, Cartiglia C, De Flora S. Oxidative deoxyribonucleic acid damage in the eyes of glaucoma patients. Am J Med. 2003;114:638-646.
    • (2003) Am J Med , vol.114 , pp. 638-646
    • Izzotti, A.1    Sacca, S.C.2    Cartiglia, C.3    de Flora, S.4
  • 13
    • 0032504657 scopus 로고    scopus 로고
    • Role of mitochondria in oxidative stress and ageing
    • Lenaz G. Role of mitochondria in oxidative stress and ageing. Biochim Biophys Acta. 1998;1366:53-67.
    • (1998) Biochim Biophys Acta , vol.1366 , pp. 53-67
    • Lenaz, G.1
  • 14
    • 37349056711 scopus 로고    scopus 로고
    • Sustained stress response after oxidative stress in trabecular meshwork cells
    • Li G, Luna C, Liton PB, Navarro I, Epstein DL, Gonzalez P. Sustained stress response after oxidative stress in trabecular meshwork cells. Mol Vis. 2007;13:2282-2288.
    • (2007) Mol Vis , vol.13 , pp. 2282-2288
    • Li, G.1    Luna, C.2    Liton, P.B.3    Navarro, I.4    Epstein, D.L.5    Gonzalez, P.6
  • 15
    • 45549087104 scopus 로고    scopus 로고
    • Mitochondrial complex I defect induces ROS release and degeneration in trabecular meshwork cells of POAG patients: Protection by antioxidants
    • He Y, Leung KW, Zhang YH, et al. Mitochondrial complex I defect induces ROS release and degeneration in trabecular meshwork cells of POAG patients: protection by antioxidants. Invest Ophthalmol Vis Sci. 2008;49:1447-1458.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 1447-1458
    • He, Y.1    Leung, K.W.2    Zhang, Y.H.3
  • 16
    • 56149101802 scopus 로고    scopus 로고
    • Mitochondrial defects and dysfunction in calcium regulation in glaucomatous trabecular meshwork cells
    • He Y, Ge J, Tombran-Tink J. Mitochondrial defects and dysfunction in calcium regulation in glaucomatous trabecular meshwork cells. Invest Ophthalmol Vis Sci. 2008;49:4912-4922.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 4912-4922
    • He, Y.1    Ge, J.2    Tombran-Tink, J.3
  • 17
    • 77953645397 scopus 로고    scopus 로고
    • Mitochondrial damage in the trabecular meshwork of patients with glaucoma
    • Izzotti A, Sacca SC, Longobardi M, Cartiglia C. Mitochondrial damage in the trabecular meshwork of patients with glaucoma. Arch Ophthalmol. 2010;128:724-730.
    • (2010) Arch Ophthalmol , vol.128 , pp. 724-730
    • Izzotti, A.1    Sacca, S.C.2    Longobardi, M.3    Cartiglia, C.4
  • 18
    • 0038051345 scopus 로고    scopus 로고
    • Mitochondria, oxidative damage, and inflammation in Parkinson's disease
    • Beal MF. Mitochondria, oxidative damage, and inflammation in Parkinson's disease. Ann NY Acad Sci. 2003;991:120-131.
    • (2003) Ann NY Acad Sci , vol.991 , pp. 120-131
    • Beal, M.F.1
  • 19
    • 0034851553 scopus 로고    scopus 로고
    • Green tea polyphenol (_)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurodegeneration
    • Levites Y, Weinreb O, Maor G, Youdim MB, Mandel S. Green tea polyphenol (_)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurodegeneration. J Neurochem. 2001;78:1073-1082.
    • (2001) J Neurochem , vol.78 , pp. 1073-1082
    • Levites, Y.1    Weinreb, O.2    Maor, G.3    Youdim, M.B.4    Mandel, S.5
  • 20
    • 33748201552 scopus 로고    scopus 로고
    • Mitochondria-targeted peptide antioxidants: Novel neuroprotective agents
    • Szeto HH. Mitochondria-targeted peptide antioxidants: novel neuroprotective agents. AAPS J. 2006;8:E521-E531.
    • (2006) AAPS J , vol.8
    • Szeto, H.H.1
  • 21
    • 4544370680 scopus 로고    scopus 로고
    • Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury
    • Zhao K, Zhao GM, Wu D, et al. Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury. J Biol Chem. 2004;279:34682-34690.
    • (2004) J Biol Chem , vol.279 , pp. 34682-34690
    • Zhao, K.1    Zhao, G.M.2    Wu, D.3
  • 22
    • 0037215549 scopus 로고    scopus 로고
    • Transcellular transport of a highly polar 3 net charge opioid tetrapeptide
    • Zhao K, Luo G, Zhao GM, Schiller PW, Szeto HH. Transcellular transport of a highly polar 3 net charge opioid tetrapeptide. J Pharmacol Exp Ther. 2003;304:425-432.
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 425-432
    • Zhao, K.1    Luo, G.2    Zhao, G.M.3    Schiller, P.W.4    Szeto, H.H.5
  • 23
    • 38349010993 scopus 로고    scopus 로고
    • Mitochondria-targeted cytoprotective peptides for ischemia-reperfusion injury
    • Szeto HH. Mitochondria-targeted cytoprotective peptides for ischemia-reperfusion injury. Antioxid Redox Signal. 2008;10:601-619.
    • (2008) Antioxid Redox Signal , vol.10 , pp. 601-619
    • Szeto, H.H.1
  • 24
    • 27744516094 scopus 로고    scopus 로고
    • Mitochondria-targeted peptide prevents mitochondrial depolarization and apoptosis induced by tert-butyl hydroperoxide in neuronal cell lines
    • Zhao K, Luo G, Giannelli S, Szeto HH. Mitochondria-targeted peptide prevents mitochondrial depolarization and apoptosis induced by tert-butyl hydroperoxide in neuronal cell lines. Biochem Pharmacol. 2005;70:1796-1806.
    • (2005) Biochem Pharmacol , vol.70 , pp. 1796-1806
    • Zhao, K.1    Luo, G.2    Giannelli, S.3    Szeto, H.H.4
  • 25
    • 38349002464 scopus 로고    scopus 로고
    • Do mitochondriotropic antioxidants prevent chlorinative stress-induced mitochondrial and cellular injury?
    • Whiteman M, Spencer JP, Szeto HH, Armstrong JS. Do mitochondriotropic antioxidants prevent chlorinative stress-induced mitochondrial and cellular injury? Antioxid Redox Signal. 2008;10: 641-650.
    • (2008) Antioxid Redox Signal , vol.10 , pp. 641-650
    • Whiteman, M.1    Spencer, J.P.2    Szeto, H.H.3    Armstrong, J.S.4
  • 26
    • 63849133179 scopus 로고    scopus 로고
    • Mitochondria-derived reactive oxygen species mediate heme oxygenase-1 expression in sheared endothelial cells
    • Han Z, Varadharaj S, Giedt RJ, Zweier JL, Szeto HH, Alevriadou BR. Mitochondria-derived reactive oxygen species mediate heme oxygenase-1 expression in sheared endothelial cells. J Pharmacol Exp Ther. 2009;329:94-101.
    • (2009) J Pharmacol Exp Ther , vol.329 , pp. 94-101
    • Han, Z.1    Varadharaj, S.2    Giedt, R.J.3    Zweier, J.L.4    Szeto, H.H.5    Alevriadou, B.R.6
  • 27
    • 1942500141 scopus 로고    scopus 로고
    • 2002 global update of available data on visual impairment: A compilation of populationbased prevalence studies
    • Pascolini D, Mariotti SP, Pokharel GP, et al. 2002 global update of available data on visual impairment: a compilation of populationbased prevalence studies. Ophthalmic Epidemiol. 2004;11:67-115.
    • (2004) Ophthalmic Epidemiol , vol.11 , pp. 67-115
    • Pascolini, D.1    Mariotti, S.P.2    Pokharel, G.P.3
  • 28
    • 30444443459 scopus 로고    scopus 로고
    • Hydrogen peroxide induces apoptotic-like cell death in coelomocytes of Themiste petricola (Sipuncula)
    • Blanco GA, Bustamante J, Garcia M, Hajos SE. Hydrogen peroxide induces apoptotic-like cell death in coelomocytes of Themiste petricola (Sipuncula). Biol Bull. 2005;209:168-183.
    • (2005) Biol Bull , vol.209 , pp. 168-183
    • Blanco, G.A.1    Bustamante, J.2    Garcia, M.3    Hajos, S.E.4
  • 29
    • 64249121678 scopus 로고    scopus 로고
    • Biological properties of trabecular meshwork cells
    • Gasiorowski JZ, Russell P. Biological properties of trabecular meshwork cells. Exp Eye Res. 2009;88:671-675.
    • (2009) Exp Eye Res , vol.88 , pp. 671-675
    • Gasiorowski, J.Z.1    Russell, P.2
  • 31
    • 0019843761 scopus 로고
    • Hydrogen peroxide and human cataract
    • Spector A, Garner WH. Hydrogen peroxide and human cataract. Exp Eye Res. 1981;33:673-681.
    • (1981) Exp Eye Res , vol.33 , pp. 673-681
    • Spector, A.1    Garner, W.H.2
  • 32
    • 0028123512 scopus 로고
    • Preliminary characterization of a transformed cell strain derived from human trabecular meshwork
    • Pang IH, Shade DL, Clark AF, Steely HT, DeSantis L. Preliminary characterization of a transformed cell strain derived from human trabecular meshwork. Curr Eye Res. 1994;13:51-63.
    • (1994) Curr Eye Res , vol.13 , pp. 51-63
    • Pang, I.H.1    Shade, D.L.2    Clark, A.F.3    Steely, H.T.4    Desantis, L.5
  • 33
    • 66849113326 scopus 로고    scopus 로고
    • Nipradilol and timolol induce Foxo3a and peroxiredoxin 2 expression and protect trabecular meshwork cells from oxidative stress
    • Miyamoto N, Izumi H, Miyamoto R, et al. Nipradilol and timolol induce Foxo3a and peroxiredoxin 2 expression and protect trabecular meshwork cells from oxidative stress. Invest Ophthalmol Vis Sci. 2009;50:2777-2784.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 2777-2784
    • Miyamoto, N.1    Izumi, H.2    Miyamoto, R.3
  • 34
    • 0242594636 scopus 로고    scopus 로고
    • Donor corneoscleral buttons: A new source of trabecular meshwork for research
    • Rhee DJ, Tamm ER, Russell P. Donor corneoscleral buttons: a new source of trabecular meshwork for research. Exp Eye Res. 2003; 77:749-756.
    • (2003) Exp Eye Res , vol.77 , pp. 749-756
    • Rhee, D.J.1    Tamm, E.R.2    Russell, P.3
  • 35
    • 0033867013 scopus 로고    scopus 로고
    • Isolation of primary open-angle glaucomatous trabecular meshwork cells from whole eye tissue
    • Stamer DW, Roberts BC, Epstein DL, Allingham RR. Isolation of primary open-angle glaucomatous trabecular meshwork cells from whole eye tissue. Curr Eye Res. 2000;20:347-350.
    • (2000) Curr Eye Res , vol.20 , pp. 347-350
    • Stamer, D.W.1    Roberts, B.C.2    Epstein, D.L.3    Allingham, R.R.4
  • 37
    • 0021043113 scopus 로고
    • Human trabecular meshwork in primary culture: A morphological and autoradiographic study
    • Grierson I, Marshall J, Robins E. Human trabecular meshwork in primary culture: a morphological and autoradiographic study. Exp Eye Res. 1983;37:349-365.
    • (1983) Exp Eye Res , vol.37 , pp. 349-365
    • Grierson, I.1    Marshall, J.2    Robins, E.3
  • 38
    • 0018889974 scopus 로고
    • Preliminary observations on human trabecular meshwork cells in vitro
    • Grierson I, Robins E, Howes RC. Preliminary observations on human trabecular meshwork cells in vitro. Graefes Arch Clin Exp Ophthalmol. 1980;212:173-186.
    • (1980) Graefes Arch Clin Exp Ophthalmol , vol.212 , pp. 173-186
    • Grierson, I.1    Robins, E.2    Howes, R.C.3
  • 39
    • 67650432133 scopus 로고    scopus 로고
    • Neuroprotection: Extrapolating from neurologic diseases to the eye
    • Danesh-Meyer HV, Levin LA. Neuroprotection: extrapolating from neurologic diseases to the eye. Am J Ophthalmol. 2009;148:186-191.e182.
    • (2009) Am J Ophthalmol , vol.148
    • Danesh-Meyer, H.V.1    Levin, L.A.2
  • 40
    • 58149185105 scopus 로고    scopus 로고
    • Resveratrol prevents the expression of glaucoma markers induced by chronic oxidative stress in trabecular meshwork cells
    • Luna C, Li G, Liton PB, et al. Resveratrol prevents the expression of glaucoma markers induced by chronic oxidative stress in trabecular meshwork cells. Food Chem Toxicol. 2009;47:198-204.
    • (2009) Food Chem Toxicol , vol.47 , pp. 198-204
    • Luna, C.1    Li, G.2    Liton, P.B.3
  • 41
    • 33847071146 scopus 로고    scopus 로고
    • Targeting antioxidants to mitochondria by conjugation to lipophilic cations
    • Murphy MP, Smith RA. Targeting antioxidants to mitochondria by conjugation to lipophilic cations. Annu Rev Pharmacol Toxicol. 2007;47:629-656.
    • (2007) Annu Rev Pharmacol Toxicol , vol.47 , pp. 629-656
    • Murphy, M.P.1    Smith, R.A.2
  • 42
    • 46349110018 scopus 로고    scopus 로고
    • Targeting lipophilic cations to mitochondria
    • Murphy MP. Targeting lipophilic cations to mitochondria. Biochim Biophys Acta. 2008;1777:1028-1031.
    • (2008) Biochim Biophys Acta , vol.1777 , pp. 1028-1031
    • Murphy, M.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.