Reactive oxygen species-mitochondria pathway involved in FV-429-induced apoptosis in human hepatocellular carcinoma HepG2 cells

Anti-Cancer Drugs

Volumn 22, Issue 9, 2011, Pages 886-895

  Yang, Zhen ^a   Qiang, Lei ^a   Wu, Tian ^a   Chen, Fei Hong ^a   Yang, Hui Ying ^a   Zhao, Qing ^a   Zou, Mei Juan ^a   Sun, Ya Jing ^a   Li, Zhi Yu ^a   Guo, Qing Long ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

apoptosis; flavonoid; mitochondria; reactive oxygen species

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 9; CLOMIFENE CITRATE; CYCLOPHOSPHAMIDE; CYTOCHROME C; FLAVONOID; FV 429; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROPIDIUM IODIDE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL STRAIN HEPG2; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; STAINING; WEIGHT;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASES; FLAVONOIDS; HEP G2 CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIVER NEOPLASMS; MALE; MICE; MITOCHONDRIA; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; RANDOM ALLOCATION; REACTIVE OXYGEN SPECIES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 80052487929     PISSN: 09594973     EISSN: 14735741     Source Type: Journal    
DOI: 10.1097/CAD.0b013e3283483d65     Document Type: Article

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