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Volumn 89, Issue 9, 2011, Pages 869-875

Non-cell-autonomous tumor suppression: Oncogene-provoked apoptosis promotes tumor cell senescence via stromal crosstalk

Author keywords

DLBCL; Lymphomagenesis; Macrophages; Senescence; TGF ; Tumor stroma

Indexed keywords

CYTOKINE; TRANSFORMING GROWTH FACTOR BETA;

EID: 80052482250     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-011-0770-2     Document Type: Review
Times cited : (3)

References (54)
  • 1
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • D Hanahan RA Weinberg 2000 The hallmarks of cancer Cell 100 1 57 70 10647931 10.1016/S0092-8674(00)81683-9 1:CAS:528:DC%2BD3cXks1CktA%3D%3D (Pubitemid 30046295)
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 0038013875 scopus 로고    scopus 로고
    • Senescence, apoptosis and therapy - Cutting the lifelines of cancer
    • CA Schmitt 2003 Senescence, apoptosis and therapy-cutting the lifelines of cancer Nat Rev Cancer 3 286 295 12671667 10.1038/nrc1044 1:CAS:528: DC%2BD3sXisFajt7Y%3D (Pubitemid 37328864)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.4 , pp. 286-295
    • Schmitt, C.A.1
  • 3
    • 0026667219 scopus 로고
    • Role for c-myc in activation-induced apoptotic cell death in T cell hybridomas
    • 1378649 10.1126/science.1378649 1:CAS:528:DyaK38XltV2qtrc%3D
    • Y Shi JM Glynn LJ Guilbert TG Cotter RP Bissonnette DR Green 1992 Role for c-myc in activation-induced apoptotic cell death in T cell hybridomas Science 257 212 214 1378649 10.1126/science.1378649 1:CAS:528:DyaK38XltV2qtrc%3D
    • (1992) Science , vol.257 , pp. 212-214
    • Shi, Y.1    Glynn, J.M.2    Guilbert, L.J.3    Cotter, T.G.4    Bissonnette, R.P.5    Green, D.R.6
  • 5
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16(INK4a)
    • DOI 10.1016/S0092-8674(00)81902-9
    • INK4a Cell 88 593 602 9054499 10.1016/S0092-8674(00)81902-9 1:CAS:528:DyaK2sXhvVSit7k%3D (Pubitemid 27152402)
    • (1997) Cell , vol.88 , Issue.5 , pp. 593-602
    • Serrano, M.1    Lin, A.W.2    McCurrach, M.E.3    Beach, D.4    Lowe, S.W.5
  • 7
    • 84965092294 scopus 로고
    • Cancer: A biological approach. I. The processes of control
    • 13404306 10.1136/bmj.1.5022.779 1:STN:280:DyaG2s%2FltVGrug%3D%3D
    • M Burnet 1957 Cancer: a biological approach. I. The processes of control Br Med J 1 779 786 13404306 10.1136/bmj.1.5022.779 1:STN:280: DyaG2s%2FltVGrug%3D%3D
    • (1957) Br Med J , vol.1 , pp. 779-786
    • Burnet, M.1
  • 8
    • 33846935228 scopus 로고    scopus 로고
    • Unique human tumor antigens: Immunobiology and use in clinical trials
    • G Parmiani A De Filippo L Novellino C Castelli 2007 Unique human tumor antigens: immunobiology and use in clinical trials J Immunol 178 1975 1979 17277099 1:CAS:528:DC%2BD2sXht1CgtLc%3D (Pubitemid 46233392)
    • (2007) Journal of Immunology , vol.178 , Issue.4 , pp. 1975-1979
    • Parmiani, G.1    De Filippo, A.2    Novellino, L.3    Castelli, C.4
  • 9
    • 77949497729 scopus 로고    scopus 로고
    • Granzymes in cancer and immunity
    • 20075940 10.1038/cdd.2009.206 1:CAS:528:DC%2BC3cXjt1OgsLg%3D
    • SP Cullen M Brunet SJ Martin 2010 Granzymes in cancer and immunity Cell Death Differ 17 616 623 20075940 10.1038/cdd.2009.206 1:CAS:528: DC%2BC3cXjt1OgsLg%3D
    • (2010) Cell Death Differ , vol.17 , pp. 616-623
    • Cullen, S.P.1    Brunet, M.2    Martin, S.J.3
  • 10
    • 53549114206 scopus 로고    scopus 로고
    • NK cells and cancer immunosurveillance
    • 18836474 10.1038/onc.2008.267 1:CAS:528:DC%2BD1cXhtF2msbnE
    • I Waldhauer A Steinle 2008 NK cells and cancer immunosurveillance Oncogene 27 5932 5943 18836474 10.1038/onc.2008.267 1:CAS:528:DC%2BD1cXhtF2msbnE
    • (2008) Oncogene , vol.27 , pp. 5932-5943
    • Waldhauer, I.1    Steinle, A.2
  • 11
    • 33847650413 scopus 로고    scopus 로고
    • Cancer immunosurveillance, immunoediting and inflammation: Independent or interdependent processes?
    • DOI 10.1016/j.coi.2007.02.001, PII S095279150700009X, Lymphocyte development/Tumour immunology
    • JD Bui RD Schreiber 2007 Cancer immunosurveillance, immunoediting and inflammation: independent or interdependent processes? Curr Opin Immunol 19 203 208 17292599 10.1016/j.coi.2007.02.001 1:CAS:528:DC%2BD2sXisleiu7c%3D (Pubitemid 46356963)
    • (2007) Current Opinion in Immunology , vol.19 , Issue.2 , pp. 203-208
    • Bui, J.D.1    Schreiber, R.D.2
  • 13
    • 0037240850 scopus 로고    scopus 로고
    • Nature's TRAIL - On a path to cancer immunotherapy
    • DOI 10.1016/S1074-7613(02)00502-2
    • MJ Smyth K Takeda Y Hayakawa JJ Peschon MR van den Brink H Yagita 2003 Nature's TRAIL-on a path to cancer immunotherapy Immunity 18 1 6 12530970 10.1016/S1074-7613(02)00502-2 1:CAS:528:DC%2BD3sXnvVykuw%3D%3D (Pubitemid 36120682)
    • (2003) Immunity , vol.18 , Issue.1 , pp. 1-6
    • Smyth, M.J.1    Takeda, K.2    Hayakawa, Y.3    Peschon, J.J.4    Van Den Brink, M.R.M.5    Yagita, H.6
  • 14
    • 67650646082 scopus 로고    scopus 로고
    • CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells
    • 19632178 10.1016/j.cell.2009.05.046 1:CAS:528:DC%2BD1MXhtVSgtr3M
    • S Jaiswal CH Jamieson WW Pang CY Park MP Chao R Majeti D Traver N van Rooijen IL Weissman 2009 CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells Cell 138 271 285 19632178 10.1016/j.cell.2009.05.046 1:CAS:528:DC%2BD1MXhtVSgtr3M
    • (2009) Cell , vol.138 , pp. 271-285
    • Jaiswal, S.1    Jamieson, C.H.2    Pang, W.W.3    Park, C.Y.4    Chao, M.P.5    Majeti, R.6    Traver, D.7    Van Rooijen, N.8    Weissman, I.L.9
  • 15
    • 33750321707 scopus 로고    scopus 로고
    • Interferons, immunity and cancer immunoediting
    • DOI 10.1038/nri1961, PII NRI1961
    • GP Dunn CM Koebel RD Schreiber 2006 Interferons, immunity and cancer immunoediting Nat Rev Immunol 6 836 848 17063185 10.1038/nri1961 1:CAS:528:DC%2BD28XhtFWns7fK (Pubitemid 44631652)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.11 , pp. 836-848
    • Dunn, G.P.1    Koebel, C.M.2    Schreiber, R.D.3
  • 16
    • 0035953308 scopus 로고    scopus 로고
    • IFNγ, and lymphocytes prevent primary tumour development and shape tumour immunogenicity
    • DOI 10.1038/35074122
    • V Shankaran H Ikeda AT Bruce JM White PE Swanson LJ Old RD Schreiber 2001 IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity Nature 410 1107 1111 11323675 10.1038/35074122 1:CAS:528:DC%2BD3MXjsVCrtr4%3D (Pubitemid 32391043)
    • (2001) Nature , vol.410 , Issue.6832 , pp. 1107-1111
    • Shankaran, V.1    Ikeda, H.2    Bruce, A.T.3    White, J.M.4    Swanson, P.E.5    Old, L.J.6    Schreiber, R.D.7
  • 19
    • 13944260728 scopus 로고    scopus 로고
    • Stromal-epithelial interactions in aging and cancer: Senescent fibroblasts alter epithelial cell differentiation
    • DOI 10.1242/jcs.01635
    • S Parrinello JP Coppe A Krtolica J Campisi 2005 Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation J Cell Sci 118 Pt 3 485 496 15657080 10.1242/jcs.01635 1:CAS:528:DC%2BD2MXhvFKntb0%3D (Pubitemid 40310116)
    • (2005) Journal of Cell Science , vol.118 , Issue.3 , pp. 485-496
    • Parrinello, S.1    Coppe, J.-P.2    Krtolica, A.3    Campisi, J.4
  • 20
    • 33749549246 scopus 로고    scopus 로고
    • Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence
    • DOI 10.1074/jbc.M603307200
    • JP Coppé K Kauser J Campisi CM Beauséjour 2006 Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence J Biol Chem 281 29568 29574 16880208 10.1074/jbc.M603307200 (Pubitemid 44536964)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.40 , pp. 29568-29574
    • Coppe, J.-P.1    Kauser, K.2    Campisi, J.3    Beausejour, C.M.4
  • 21
    • 77949881221 scopus 로고    scopus 로고
    • The senescence-associated secretory phenotype: The dark side of tumor suppression
    • 20078217 10.1146/annurev-pathol-121808-102144
    • JP Coppé PY Desprez A Krtolica J Campisi 2010 The senescence-associated secretory phenotype: the dark side of tumor suppression Annu Rev Pathol 5 99 118 20078217 10.1146/annurev-pathol-121808-102144
    • (2010) Annu Rev Pathol , vol.5 , pp. 99-118
    • Coppé, J.P.1    Desprez, P.Y.2    Krtolica, A.3    Campisi, J.4
  • 22
    • 33846937033 scopus 로고    scopus 로고
    • Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
    • DOI 10.1038/nature05529, PII NATURE05529
    • W Xue L Zender C Miething RA Dickins E Hernando V Krizhanovsky C Cordon-Cardo SW Lowe 2007 Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas Nature 445 656 660 17251933 10.1038/nature05529 1:CAS:528:DC%2BD2sXhtlOrtbo%3D (Pubitemid 46232886)
    • (2007) Nature , vol.445 , Issue.7128 , pp. 656-660
    • Xue, W.1    Zender, L.2    Miething, C.3    Dickins, R.A.4    Hernando, E.5    Krizhanovsky, V.6    Cordon-Cardo, C.7    Lowe, S.W.8
  • 24
    • 38849168162 scopus 로고    scopus 로고
    • Oncogenic BRAF Induces Senescence and Apoptosis through Pathways Mediated by the Secreted Protein IGFBP7
    • DOI 10.1016/j.cell.2007.12.032, PII S0092867408000536
    • N Wajapeyee RW Serra X Zhu M Mahalingam MR Green 2008 Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7 Cell 132 363 374 18267069 10.1016/j.cell.2007.12.032 1:CAS:528:DC%2BD1cXivVahtbc%3D (Pubitemid 351191995)
    • (2008) Cell , vol.132 , Issue.3 , pp. 363-374
    • Wajapeyee, N.1    Serra, R.W.2    Zhu, X.3    Mahalingam, M.4    Green, M.R.5
  • 25
    • 44649101304 scopus 로고    scopus 로고
    • Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network
    • DOI 10.1016/j.cell.2008.03.039, PII S009286740800620X
    • C Kuilman LC Michaloglou S Vredeveld R Douma CJ van Doorn LA Desmet WJ Aarden WJ Mooi DS Peeper 2008 Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network Cell 133 1019 1031 18555778 10.1016/j.cell.2008.03.039 1:CAS:528:DC%2BD1cXnsF2gtbs%3D (Pubitemid 351787746)
    • (2008) Cell , vol.133 , Issue.6 , pp. 1019-1031
    • Kuilman, T.1    Michaloglou, C.2    Vredeveld, L.C.W.3    Douma, S.4    Van Doorn, R.5    Desmet, C.J.6    Aarden, L.A.7    Mooi, W.J.8    Peeper, D.S.9
  • 28
    • 34548188741 scopus 로고    scopus 로고
    • Self-eating and self-killing: Crosstalk between autophagy and apoptosis
    • DOI 10.1038/nrm2239, PII NRM2239
    • MC Maiuri E Zalckvar A Kimchi G Kroemer 2007 Self-eating and self-killing: crosstalk between autophagy and apoptosis Nat Rev Mol Cell Biol 8 741 752 17717517 10.1038/nrm2239 1:CAS:528:DC%2BD2sXpsVartb8%3D (Pubitemid 47312826)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.9 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 29
    • 33847404337 scopus 로고    scopus 로고
    • Autophagy Gene-Dependent Clearance of Apoptotic Cells during Embryonic Development
    • DOI 10.1016/j.cell.2006.12.044, PII S009286740700178X
    • X Qu Z Zou Q Sun K Luby-Phelps P Cheng RN Hogan C Gilpin B Levine 2007 Autophagy gene-dependent clearance of apoptotic cells during embryonic development Cell 128 931 946 17350577 10.1016/j.cell.2006.12.044 1:CAS:528:DC%2BD2sXjvVSgu7c%3D (Pubitemid 46341412)
    • (2007) Cell , vol.128 , Issue.5 , pp. 931-946
    • Qu, X.1    Zou, Z.2    Sun, Q.3    Luby-Phelps, K.4    Cheng, P.5    Hogan, R.N.6    Gilpin, C.7    Levine, B.8
  • 30
    • 77649295810 scopus 로고    scopus 로고
    • Tumor stroma-derived TGF-β limits myc-driven lymphomagenesis via Suv39h1-dependent senescence
    • 20227040 10.1016/j.ccr.2009.12.043 1:CAS:528:DC%2BC3cXlsVWqtLc%3D
    • M Reimann S Lee C Loddenkemper JR Dörr V Tabor P Aichele H Stein B Dörken T Jenuwein CA Schmitt 2010 Tumor stroma-derived TGF-β limits myc-driven lymphomagenesis via Suv39h1-dependent senescence Cancer Cell 17 262 272 20227040 10.1016/j.ccr.2009.12.043 1:CAS:528:DC%2BC3cXlsVWqtLc%3D
    • (2010) Cancer Cell , vol.17 , pp. 262-272
    • Reimann, M.1    Lee, S.2    Loddenkemper, C.3    Dörr, J.R.4    Tabor, V.5    Aichele, P.6    Stein, H.7    Dörken, B.8    Jenuwein, T.9    Schmitt, C.A.10
  • 31
    • 57149089307 scopus 로고    scopus 로고
    • Stromal gene signatures in large-B-cell lymphomas
    • Lymphoma/Leukemia Molecular Profiling Project et al. 19038878 10.1056/NEJMoa0802885 1:CAS:528:DC%2BD1cXhsVehtbvF
    • G Lenz G Wright SS Dave W Xiao J Powell H Zhao W Xu B Tan N Goldschmidt J Iqbal Lymphoma/Leukemia Molecular Profiling Project, et al. 2008 Stromal gene signatures in large-B-cell lymphomas N Engl J Med 359 2313 2323 19038878 10.1056/NEJMoa0802885 1:CAS:528:DC%2BD1cXhsVehtbvF
    • (2008) N Engl J Med , vol.359 , pp. 2313-2323
    • Lenz, G.1    Wright, G.2    Dave, S.S.3    Xiao, W.4    Powell, J.5    Zhao, H.6    Xu, W.7    Tan, B.8    Goldschmidt, N.9    Iqbal, J.10
  • 33
    • 27644457376 scopus 로고    scopus 로고
    • TGF-β directly targets cytotoxic T cell functions during tumor evasion of immune surveillance
    • DOI 10.1016/j.ccr.2005.10.012, PII S1535610805003314
    • DA Thomas J Massagué 2005 TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance J Cancer Cell 8 369 380 10.1016/j.ccr.2005.10.012 1:CAS:528:DC%2BD2MXht12gsbvK (Pubitemid 41579832)
    • (2005) Cancer Cell , vol.8 , Issue.5 , pp. 369-380
    • Thomas, D.A.1    Massague, J.2
  • 34
    • 0033521118 scopus 로고    scopus 로고
    • INK4B induction and growth inhibition in astrocytes Is SMAD3-dependent and a pathway prominently altered in human glioma cell lines
    • JN Rich M Zhang MB Datto DD Bigner XF Wang 1999 Transforming growth factor-beta-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines J Biol Chem 274 35053 35058 10574984 10.1074/jbc.274.49.35053 1:CAS:528: DyaK1MXnvFyrtL0%3D (Pubitemid 129509557)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.49 , pp. 35053-35058
    • Rich, J.N.1    Zhang, M.2    Datto, M.B.3    Bigner, D.D.4    Wang, X.-F.5
  • 36
    • 1642332084 scopus 로고    scopus 로고
    • Integration of smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation
    • DOI 10.1016/S0092-8674(04)00298-3, PII S0092867404002983
    • J Seoane HV Le L Shen SA Anderson J Massagué 2004 Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation Cell 117 211 223 15084259 10.1016/S0092-8674(04)00298-3 1:CAS:528:DC%2BD2cXjsFyrurc%3D (Pubitemid 38496241)
    • (2004) Cell , vol.117 , Issue.2 , pp. 211-223
    • Seoane, J.1    Le, H.-V.2    Shen, L.3    Anderson, S.A.4    Massague, J.5
  • 37
    • 47549090432 scopus 로고    scopus 로고
    • TGFβ in Cancer
    • DOI 10.1016/j.cell.2008.07.001, PII S0092867408008787
    • J Massagué 2008 TGFbeta in cancer Cell 134 215 230 18662538 10.1016/j.cell.2008.07.001 (Pubitemid 352010335)
    • (2008) Cell , vol.134 , Issue.2 , pp. 215-230
    • Massague, J.1
  • 38
    • 77953917870 scopus 로고    scopus 로고
    • The interaction between Myc and Miz1 is required to antagonize TGF β-dependent autocrine signaling during lymphoma formation and maintenance
    • 20551174 10.1101/gad.585710
    • J van Riggelen J Müller T Otto V Beuger A Yetil PS Choi C Kosan T Möröy DW Felsher M Eilers 2010 The interaction between Myc and Miz1 is required to antagonize TGF β-dependent autocrine signaling during lymphoma formation and maintenance Genes Dev 24 12 1281 1294 20551174 10.1101/gad.585710
    • (2010) Genes Dev , vol.24 , Issue.12 , pp. 1281-1294
    • Van Riggelen, J.1    Müller, J.2    Otto, T.3    Beuger, V.4    Yetil, A.5    Choi, P.S.6    Kosan, C.7    Möröy, T.8    Felsher, D.W.9    Eilers, M.10
  • 39
    • 17644394616 scopus 로고    scopus 로고
    • Smoldering and polarized inflammation in the initiation and promotion of malignant disease
    • DOI 10.1016/j.ccr.2005.02.013
    • F Balkwill KA Charles A Mantovani 2005 Smoldering and polarized inflammation in the initiation and promotion of malignant disease Cancer Cell 7 211 217 15766659 10.1016/j.ccr.2005.02.013 1:CAS:528:DC%2BD2MXivFCqurk%3D (Pubitemid 40568680)
    • (2005) Cancer Cell , vol.7 , Issue.3 , pp. 211-217
    • Balkwill, F.1    Charles, K.A.2    Mantovani, A.3
  • 40
    • 7644231561 scopus 로고    scopus 로고
    • The chemokine system in diverse forms of macrophage activation and polarization
    • DOI 10.1016/j.it.2004.09.015, PII S1471490604002959
    • A Mantovani A Sica S Sozzani P Allavena A Vecchi M Locati 2004 The chemokine system in diverse forms of macrophage activation and polarization Trends Immunol 25 677 686 15530839 10.1016/j.it.2004.09.015 1:CAS:528: DC%2BD2cXptl2ktbs%3D (Pubitemid 39457982)
    • (2004) Trends in Immunology , vol.25 , Issue.12 , pp. 677-686
    • Mantovani, A.1    Sica, A.2    Sozzani, S.3    Allavena, P.4    Vecchi, A.5    Locati, M.6
  • 41
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • DOI 10.1038/nri978
    • S Gordon 2003 Alternative activation of macrophages Nat Rev Immunol 3 23 35 12511873 10.1038/nri978 1:CAS:528:DC%2BD3sXovVw%3D (Pubitemid 37328697)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.1 , pp. 23-35
    • Gordon, S.1
  • 42
    • 33645991795 scopus 로고    scopus 로고
    • Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy
    • 16520032 10.1016/j.ejca.2006.01.003 1:CAS:528:DC%2BD28Xjs1Grt78%3D
    • A Sica T Schioppa A Mantovani P Allavena 2006 Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy Eur J Cancer 42 717 727 16520032 10.1016/j.ejca.2006.01.003 1:CAS:528:DC%2BD28Xjs1Grt78%3D
    • (2006) Eur J Cancer , vol.42 , pp. 717-727
    • Sica, A.1    Schioppa, T.2    Mantovani, A.3    Allavena, P.4
  • 43
    • 33746926292 scopus 로고    scopus 로고
    • Clodronate-liposome-mediated depletion of tumour-associated macrophages: A new and highly effective antiangiogenic therapy approach
    • DOI 10.1038/sj.bjc.6603240, PII 6603240
    • SM Zeisberger B Odermatt C Marty AH Zehnder-Fjällman K Ballmer-Hofer RA Schwendener 2006 Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach Br J Cancer 95 272 281 16832418 10.1038/sj.bjc.6603240 1:CAS:528:DC%2BD28Xnsl2iu7o%3D (Pubitemid 44187587)
    • (2006) British Journal of Cancer , vol.95 , Issue.3 , pp. 272-281
    • Zeisberger, S.M.1    Odermatt, B.2    Marty, C.3    Zehnder-Fjallman, A.H.M.4    Ballmer-Hofer, K.5    Schwendener, R.A.6
  • 44
    • 46749133932 scopus 로고    scopus 로고
    • Expression of CD68+ tumor-associated macrophages in patients with diffuse large B-cell lymphoma and its relation to prognosis
    • DOI 10.1111/j.1440-1827.2008.02268.x
    • S Hasselblom U Hansson M Sigurdardottir H Nilsson-Ehle B Ridell PO Andersson 2008 Expression of CD68+ tumor-associated macrophages in patients with diffuse large B-cell lymphoma and its relation to prognosis Pathol Int 58 8 529 532 18705775 10.1111/j.1440-1827.2008.02268.x (Pubitemid 351952031)
    • (2008) Pathology International , vol.58 , Issue.8 , pp. 529-532
    • Hasselblom, S.1    Hansson, U.2    Sigurdardottir, M.3    Nilsson-Ehle, H.4    Ridell, B.5    Andersson, P.-O.6
  • 45
    • 78249257291 scopus 로고    scopus 로고
    • CD4(+) T cells contribute to the remodeling of the microenvironment required for sustained tumor regression upon oncogene inactivation
    • 21035406 10.1016/j.ccr.2010.10.002 1:CAS:528:DC%2BC3cXhsValtLrI
    • K Rakhra P Bachireddy T Zabuawala R Zeiser L Xu A Kopelman AC Fan Q Yang L Braunstein E Crosby S Ryeom DW Felsher 2010 CD4(+) T cells contribute to the remodeling of the microenvironment required for sustained tumor regression upon oncogene inactivation Cancer Cell 18 5 485 498 21035406 10.1016/j.ccr.2010.10. 002 1:CAS:528:DC%2BC3cXhsValtLrI
    • (2010) Cancer Cell , vol.18 , Issue.5 , pp. 485-498
    • Rakhra, K.1    Bachireddy, P.2    Zabuawala, T.3    Zeiser, R.4    Xu, L.5    Kopelman, A.6    Fan, A.C.7    Yang, Q.8    Braunstein, L.9    Crosby, E.10    Ryeom, S.11    Felsher, D.W.12
  • 47
    • 35548956063 scopus 로고    scopus 로고
    • The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo
    • DOI 10.1182/blood-2007-02-075614
    • M Reimann C Loddenkemper C Rudolph I Schildhauer B Teichmann H Stein B Schlegelberger B Dörken CA Schmitt 2007 The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo Blood 110 2996 3004 17562874 10.1182/blood-2007-02-075614 1:CAS:528:DC%2BD2sXht1Smu7%2FI (Pubitemid 350006954)
    • (2007) Blood , vol.110 , Issue.8 , pp. 2996-3004
    • Reimann, M.1    Loddenkemper, C.2    Rudolph, C.3    Schildhauer, I.4    Teichmann, B.5    Stein, H.6    Schlegelberger, B.7    Dorken, B.8    Schmitt, C.A.9
  • 50
    • 0036744016 scopus 로고    scopus 로고
    • Macrophages in gene therapy: Cellular delivery vehicles and in vivo targets
    • 12223508 1:CAS:528:DC%2BD38XntlOnurg%3D
    • B Burke S Sumner N Maitland CE Lewis 2002 Macrophages in gene therapy: cellular delivery vehicles and in vivo targets J Leukoc Biol 72 417 428 12223508 1:CAS:528:DC%2BD38XntlOnurg%3D
    • (2002) J Leukoc Biol , vol.72 , pp. 417-428
    • Burke, B.1    Sumner, S.2    Maitland, N.3    Lewis, C.E.4
  • 51
    • 17144398046 scopus 로고    scopus 로고
    • Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection
    • C Guiducci AP Vicari S Sangaletti G Trinchieri MP Colombo 2005 Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection Cancer Res 65 3437 3446 15833879 1:CAS:528: DC%2BD2MXjt1yrtr8%3D (Pubitemid 40524630)
    • (2005) Cancer Research , vol.65 , Issue.8 , pp. 3437-3446
    • Guiducci, C.1    Vicari, A.P.2    Sangaletti, S.3    Trinchieri, G.4    Colombo, M.P.5
  • 53
    • 11844277698 scopus 로고    scopus 로고
    • Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease
    • P Sinha VK Clements S Ostrand-Rosenberg 2005 Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease J Immunol 174 636 645 15634881 1:CAS:528:DC%2BD2MXotFSg (Pubitemid 40094255)
    • (2005) Journal of Immunology , vol.174 , Issue.2 , pp. 636-645
    • Sinha, P.1    Clements, V.K.2    Ostrand-Rosenberg, S.3


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