Resolution of cutaneous inflammation after local elimination of macrophages

Nature Biotechnology

Volumn 18, Issue 1, 2000, Pages 48-51

  Thepen, Theo ^a   Van Vuuren, A J Hanneke ^a   Kiekens, Rebecca C M ^a   Damen, Cora A ^a   Vooijs, Wim C ^b   Van De Winkel, Jan G J ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

Fc RI; Immunotoxin; Inflammation; Macrophage; Transgenic

Indexed keywords

CD64 ANTIGEN; DODECYL SULFATE SODIUM; IMMUNOTOXIN; RICIN A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; IN VITRO STUDY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN INFLAMMATION; SKIN TEMPERATURE; TREATMENT OUTCOME; VASODILATATION;

ANIMALS; ANTIBODIES, MONOCLONAL; APOPTOSIS; BODY TEMPERATURE; CHRONIC DISEASE; DERMATITIS; DERMATITIS, ATOPIC; HUMANS; IMMUNOTOXINS; INJECTIONS, INTRADERMAL; INTERFERON TYPE II; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, TRANSGENIC; RECEPTORS, FC; RECEPTORS, IGG; RICIN; SKIN; SODIUM DODECYL SULFATE; TIME FACTORS; U937 CELLS; VASODILATION;

ANIMALIA; MUS MUSCULUS;

EID: 0033986656     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/71908     Document Type: Article

References (26)

1. Williams, I.R. & Kupper, T.S. Immunity at the surface: homeostatic mechanisms of the skin immune system. Life Sci. 58, 1485-1507 (1996).
2. Stingl, G. The skin: initiation and target site of immune responses. Recent Results Cancer Res. 128, 45-57 (1993).
3. Ganz, T. Macrophage function. New Horiz. 1, 23-27 (1993).
4. Gordon, S. The macrophage. Bioessays 17, 977-986 (1995).
5. Thepen, T., Kraal, G. & Holt, P.G. The role of alveolar macrophages in regulation of lung inflammation. Ann. N. Y. Acad. Sci. 725, 200-206 (1994).
6. Holt, P.G. et al. Downregulation of the antigen presenting cell function(s) of pulmonary dendritic cells in vivo by resident alveolar macrophages. J. Exp. Med. 177, 397-407 (1993).
7. Strickland, D., Kees, U.R. & Holt, P.G. Regulation of T-cell activation in the lung: alveolar macrophages induce reversible T-cell anergy in vitro associated with inhibition of interleukin-2 receptor signal transduction. Immunology 87, 250-258 (1996).
8. Thepen, T. et al. Biphasic response against aeroallergen in atopic dermatitis showing a switch from an initial TH2 response to a TH1 response in situ: an immunocytochemical study. J. Allergy Clin. Immunol. 97, 828-837 (1996).
9. Grewe, M. et al. A role for Th1 and Th2 cells in the immunopathogenesis of atopic dermatitis, Immunol. Today 19, 359-361 (1998).
10. Avice, M-N. et al. IL-15 promotes IL-12 production by human monocytes via T cell-dependent contact and may contribute to IL-12 mediated IFN-γ secretion by CD4+ T cells in the absence of TCR ligation. J. Immunol. 161, 3408-3415 (1998).
11. Laskin, D.L. & Pendino, K.J. Macrophages and inflammatory mediators in tissue injury. Annu. Rev. Pharmacol. Toxicol. 35, 655-677 (1995).
12. Gonzalez-Ramos, A., Cooper, K.D. & Hammerberg, C. Identification of a human dermal macrophage population responsible for constitutive restraint of primary dermal fibroblast proliferation. J. Invest. Dermatol. 106, 305-311 (1996).
13. Deo, Y.M., Graziano, R.F., Repp, R. & van de Winkel, J.G.J. Clinical significance of IgG Fc receptors and Fc gamma R-directed immunotherapies, Immunol. Today 18, 127-135 (1997).
14. Ravetch, J.V. Fc receptors. Curr. Opin. Immunol. 9, 121-125 (1997).
15. Davis, B.H., Bigelow, N.C., Curnutte, J.T. & Ornvold, K. Neutrophil CD64 expression: potential diagnostic indicator of acute inflammation and therapeutic monitor of interferon gamma therapy. Lab. Hematol. 1, 3-9 (1995).
16. Guyre, P.M., Morganelli, P.M. & Miller, R. Recombinant immune interferon increases immunoglobulin G Fc receptors on cultured human mononuclear phagocytes. J. Clin. Invest. 72, 393-397 (1983).
17. Heijnen, I.A. et al. Antigen targeting to myeloid-specific human Fc gamma RI/CD64 triggers enhanced antibody responses in transgenic mice. J. Clin. Invest. 97, 331-338 (1996).
18. Trush, G.R., Lark, LR., Clinchy, B.C. & Vitetta, E.S. Immunotoxins: an update. Ann. Rev. Immunol. 14, 49-71 (1996).
19. Guyre, P.M., Graziano, R.F., Vance, B.A., Morganelli, P.M. & Fanger, M.W. Monoclonal antibodies that bind to distinct epitopes on Fc gamma RI are able to trigger receptor function. J. Immunol. 143, 1650-1655 (1989).
20. Graziano, R.F. et al. Construction and characterization of a humanized anti-gamma-Ig receptor type I (Fc gamma RI) monoclonal antibody. J. Immunol. 155, 4996-5002 (1995).
21. van Vugt, M.J., van der Herik-Oudijk, I.E., & van de Winkel, J.G.J. Fc gamma RIa/gamma-chain complexes trigger antibody-dependent cell-mediated cytotoxicity (ADCC) in CD5+ B cell/macrophage IIA1.6 cells. Clin. Exp. Immunol. 113, 415-422 (1998).
22. Post, J., Vooys, W.C., de Gast, G.G. & Bast, B.J. Comparison of various in vitro assays for efficacy screening of immunotoxins. Leuk. Res. 19, 241-247 (1995).
23. Nicoletti, I., Migliorati, G., Pagliacci, M.C., Grignani, F. & Riccardi, C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods 139, 271-279 (1991).
24. Kraal, G., Rep, M. & Janse, M. Macrophages in T and B cell compartments and other tissue macrophages recognized by monoclonal antibody MOMA-2. An immunohistochemical study. Scand. J. Immunol. 26, 653-661 (1987).
25. Kraal, G., Breel, M., Janse, M. & Bruin, G. Langerhans' cells, veiled cells, and interdigitating cells in the mouse recognized by a monoclonal antibody. J. Exp. Med. 163, 981-997 (1986).
26. Tomonari, K. A rat antibody against a structure functionally related to the mouse T- cell receptor/T3 complex. Immunogenetics 28, 455-458 (1988).