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Volumn 43, Issue 10, 2011, Pages 807-813

Redistribution of regulatory T-cells across the evolving stages of chronic hepatitis C

Author keywords

Chronic HCV related liver disease; Decompensated cirrhosis; MELD score; Regulatory T cells

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; GAMMA INTERFERON; TRANSCRIPTION FACTOR FOXP3;

EID: 80052468549     PISSN: 15908658     EISSN: 18783562     Source Type: Journal    
DOI: 10.1016/j.dld.2011.04.020     Document Type: Article
Times cited : (9)

References (40)
  • 1
    • 59149083248 scopus 로고    scopus 로고
    • The history of the "natural history" of hepatitis C (1968-2009)
    • Seeff L.B. The history of the "natural history" of hepatitis C (1968-2009). Liver Int 2009, 29(Suppl. 1):89-99.
    • (2009) Liver Int , vol.29 , Issue.SUPPL. 1 , pp. 89-99
    • Seeff, L.B.1
  • 2
    • 76049097477 scopus 로고    scopus 로고
    • HCV-related hepatocellular carcinoma: from chronic inflammation to cancer
    • Castello G., Scala S., Palmieri G., et al. HCV-related hepatocellular carcinoma: from chronic inflammation to cancer. Clin Immunol 2010, 134:237-250.
    • (2010) Clin Immunol , vol.134 , pp. 237-250
    • Castello, G.1    Scala, S.2    Palmieri, G.3
  • 3
    • 65449136656 scopus 로고    scopus 로고
    • Diagnosis, management, and treatment of hepatitis C: an update
    • Ghany M.G., Strader D.B., Thomas D.L., et al. Diagnosis, management, and treatment of hepatitis C: an update. Hepatology 2009, 49:1335-1374.
    • (2009) Hepatology , vol.49 , pp. 1335-1374
    • Ghany, M.G.1    Strader, D.B.2    Thomas, D.L.3
  • 4
    • 64749091883 scopus 로고    scopus 로고
    • New insights into the immunopathogenesis of chronic hepatitis C
    • Diepolder H.M. New insights into the immunopathogenesis of chronic hepatitis C. Antiviral Res 2009, 82:103-109.
    • (2009) Antiviral Res , vol.82 , pp. 103-109
    • Diepolder, H.M.1
  • 5
    • 77956262321 scopus 로고    scopus 로고
    • Hepatitis C virus infection: a "liaison a trois" amongst the virus, the host, and chronic low-level inflammation for human survival
    • Barnaba V. Hepatitis C virus infection: a "liaison a trois" amongst the virus, the host, and chronic low-level inflammation for human survival. J Hepatol 2010, 53:752-761.
    • (2010) J Hepatol , vol.53 , pp. 752-761
    • Barnaba, V.1
  • 6
    • 33751523588 scopus 로고    scopus 로고
    • Functional dynamics of naturally occurring regulatory T cells in health and autoimmunity
    • Levings M.K., Allan S., d'Hennezel E., et al. Functional dynamics of naturally occurring regulatory T cells in health and autoimmunity. Adv Immunol 2006, 92:119-155.
    • (2006) Adv Immunol , vol.92 , pp. 119-155
    • Levings, M.K.1    Allan, S.2    d'Hennezel, E.3
  • 7
    • 33745832286 scopus 로고    scopus 로고
    • Regulation of trafficking receptor expression in human forkhead box P3+ regulatory T cells
    • Lim H.W., Broxmeyer H.E., Kim C.H. Regulation of trafficking receptor expression in human forkhead box P3+ regulatory T cells. J Immunol 2006, 177:840-851.
    • (2006) J Immunol , vol.177 , pp. 840-851
    • Lim, H.W.1    Broxmeyer, H.E.2    Kim, C.H.3
  • 8
    • 33746342994 scopus 로고    scopus 로고
    • Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease
    • Sakaguchi S., Ono M., Setoguchi R., et al. Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease. Immunol Rev 2006, 212:8-27.
    • (2006) Immunol Rev , vol.212 , pp. 8-27
    • Sakaguchi, S.1    Ono, M.2    Setoguchi, R.3
  • 9
    • 33746365086 scopus 로고    scopus 로고
    • The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells
    • Shevach E.M., DiPaolo R.A., Andersson J., et al. The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells. Immunol Rev 2006, 212:60-73.
    • (2006) Immunol Rev , vol.212 , pp. 60-73
    • Shevach, E.M.1    DiPaolo, R.A.2    Andersson, J.3
  • 10
    • 36348988986 scopus 로고    scopus 로고
    • T-cell regulation by CD4 regulatory T cells during hepatitis B and C virus infections: facts and controversies
    • Manigold T., Racanelli V. T-cell regulation by CD4 regulatory T cells during hepatitis B and C virus infections: facts and controversies. Lancet Infect Dis 2007, 7:804-813.
    • (2007) Lancet Infect Dis , vol.7 , pp. 804-813
    • Manigold, T.1    Racanelli, V.2
  • 11
    • 51349168951 scopus 로고    scopus 로고
    • Regulatory T cells in health and disease
    • Piccirillo C.A. Regulatory T cells in health and disease. Cytokine 2008, 43:395-401.
    • (2008) Cytokine , vol.43 , pp. 395-401
    • Piccirillo, C.A.1
  • 12
    • 33747804003 scopus 로고    scopus 로고
    • Elevated CD4+/CD25+ T cell frequency and function during acute hepatitis C presage chronic evolution
    • Perrella A., Vitiello L., Atripaldi L., et al. Elevated CD4+/CD25+ T cell frequency and function during acute hepatitis C presage chronic evolution. Gut 2006, 55:1370-1371.
    • (2006) Gut , vol.55 , pp. 1370-1371
    • Perrella, A.1    Vitiello, L.2    Atripaldi, L.3
  • 13
    • 0345017746 scopus 로고    scopus 로고
    • Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection
    • Sugimoto K., Ikeda F., Stadanlick J., et al. Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection. Hepatology 2003, 38:1437-1448.
    • (2003) Hepatology , vol.38 , pp. 1437-1448
    • Sugimoto, K.1    Ikeda, F.2    Stadanlick, J.3
  • 14
    • 0038374730 scopus 로고    scopus 로고
    • Detection of functionally altered hepatitis C virus-specific CD4 T cells in acute and chronic hepatitis C
    • Ulsenheimer A., Gerlach J.T., Gruener N.H., et al. Detection of functionally altered hepatitis C virus-specific CD4 T cells in acute and chronic hepatitis C. Hepatology 2003, 37:1189-1198.
    • (2003) Hepatology , vol.37 , pp. 1189-1198
    • Ulsenheimer, A.1    Gerlach, J.T.2    Gruener, N.H.3
  • 15
    • 70349429634 scopus 로고    scopus 로고
    • FOXP3 expression in hepatitis C virus-specific CD4+ T cells during acute hepatitis C
    • 1280-8.e1-6
    • Heeg M.H., Ulsenheimer A., Gruner N.H., et al. FOXP3 expression in hepatitis C virus-specific CD4+ T cells during acute hepatitis C. Gastroenterology 2009, 137. 1280-8.e1-6.
    • (2009) Gastroenterology , vol.137
    • Heeg, M.H.1    Ulsenheimer, A.2    Gruner, N.H.3
  • 16
    • 19944370822 scopus 로고    scopus 로고
    • T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection
    • Boettler T., Spangenberg H.C., Neumann-Haefelin C., et al. T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection. J Virol 2005, 79:7860-7867.
    • (2005) J Virol , vol.79 , pp. 7860-7867
    • Boettler, T.1    Spangenberg, H.C.2    Neumann-Haefelin, C.3
  • 17
    • 33645857965 scopus 로고    scopus 로고
    • Increased hepatitis C virus (HCV)-specific CD4+CD25+ regulatory T lymphocytes and reduced HCV-specific CD4+ T cell response in HCV-infected patients with normal versus abnormal alanine aminotransferase levels
    • Bolacchi F., Sinistro A., Ciaprini C., et al. Increased hepatitis C virus (HCV)-specific CD4+CD25+ regulatory T lymphocytes and reduced HCV-specific CD4+ T cell response in HCV-infected patients with normal versus abnormal alanine aminotransferase levels. Clin Exp Immunol 2006, 144:188-196.
    • (2006) Clin Exp Immunol , vol.144 , pp. 188-196
    • Bolacchi, F.1    Sinistro, A.2    Ciaprini, C.3
  • 18
    • 7044247947 scopus 로고    scopus 로고
    • An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection
    • Cabrera R., Tu Z., Xu Y., et al. An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection. Hepatology 2004, 40:1062-1071.
    • (2004) Hepatology , vol.40 , pp. 1062-1071
    • Cabrera, R.1    Tu, Z.2    Xu, Y.3
  • 19
    • 43249107955 scopus 로고    scopus 로고
    • Identification and in vitro expansion of functional antigen-specific CD25+ FoxP3+ regulatory T cells in hepatitis C virus infection
    • Ebinuma H., Nakamoto N., Li Y., et al. Identification and in vitro expansion of functional antigen-specific CD25+ FoxP3+ regulatory T cells in hepatitis C virus infection. J Virol 2008, 82:5043-5053.
    • (2008) J Virol , vol.82 , pp. 5043-5053
    • Ebinuma, H.1    Nakamoto, N.2    Li, Y.3
  • 20
    • 77953230741 scopus 로고    scopus 로고
    • Characterization and role of intra-hepatic regulatory T cells in chronic hepatitis C pathogenesis
    • Sturm N., Thelu M.A., Camous X., et al. Characterization and role of intra-hepatic regulatory T cells in chronic hepatitis C pathogenesis. J Hepatol 2010, 53:25-35.
    • (2010) J Hepatol , vol.53 , pp. 25-35
    • Sturm, N.1    Thelu, M.A.2    Camous, X.3
  • 21
    • 34547604820 scopus 로고    scopus 로고
    • Quantification and localisation of FOXP3+ T lymphocytes and relation to hepatic inflammation during chronic HCV infection
    • Ward S.M., Fox B.C., Brown P.J., et al. Quantification and localisation of FOXP3+ T lymphocytes and relation to hepatic inflammation during chronic HCV infection. J Hepatol 2007, 47:316-324.
    • (2007) J Hepatol , vol.47 , pp. 316-324
    • Ward, S.M.1    Fox, B.C.2    Brown, P.J.3
  • 22
    • 34250005419 scopus 로고    scopus 로고
    • Increased regulatory T cells correlate with CD8 T-cell impairment and poor survival in hepatocellular carcinoma patients
    • Fu J., Xu D., Liu Z., et al. Increased regulatory T cells correlate with CD8 T-cell impairment and poor survival in hepatocellular carcinoma patients. Gastroenterology 2007, 132:2328-2339.
    • (2007) Gastroenterology , vol.132 , pp. 2328-2339
    • Fu, J.1    Xu, D.2    Liu, Z.3
  • 23
    • 34447277894 scopus 로고    scopus 로고
    • Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection
    • Gao Q., Qiu S.J., Fan J., et al. Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection. J Clin Oncol 2007, 25:2586-2593.
    • (2007) J Clin Oncol , vol.25 , pp. 2586-2593
    • Gao, Q.1    Qiu, S.J.2    Fan, J.3
  • 24
    • 33847384529 scopus 로고    scopus 로고
    • FOXP3+ regulatory T cells affect the development and progression of hepatocarcinogenesis
    • Kobayashi N., Hiraoka N., Yamagami W., et al. FOXP3+ regulatory T cells affect the development and progression of hepatocarcinogenesis. Clin Cancer Res 2007, 13:902-911.
    • (2007) Clin Cancer Res , vol.13 , pp. 902-911
    • Kobayashi, N.1    Hiraoka, N.2    Yamagami, W.3
  • 25
    • 16844378685 scopus 로고    scopus 로고
    • Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma
    • Ormandy L.A., Hillemann T., Wedemeyer H., et al. Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma. Cancer Res 2005, 65:2457-2464.
    • (2005) Cancer Res , vol.65 , pp. 2457-2464
    • Ormandy, L.A.1    Hillemann, T.2    Wedemeyer, H.3
  • 26
    • 33745699342 scopus 로고    scopus 로고
    • Increase of CD4+ CD25+ regulatory T-cells in the liver of patients with hepatocellular carcinoma
    • Yang X.H., Yamagiwa S., Ichida T., et al. Increase of CD4+ CD25+ regulatory T-cells in the liver of patients with hepatocellular carcinoma. J Hepatol 2006, 45:254-262.
    • (2006) J Hepatol , vol.45 , pp. 254-262
    • Yang, X.H.1    Yamagiwa, S.2    Ichida, T.3
  • 27
    • 77954354546 scopus 로고    scopus 로고
    • Expansion of CD4(+)CD25(+)FoxP3(+) regulatory T cells in hepatitis C virus-related chronic hepatitis, cirrhosis and hepatocellular carcinoma
    • Yoshizawa K., Abe H., Kubo Y., et al. Expansion of CD4(+)CD25(+)FoxP3(+) regulatory T cells in hepatitis C virus-related chronic hepatitis, cirrhosis and hepatocellular carcinoma. Hepatol Res 2010, 40:179-187.
    • (2010) Hepatol Res , vol.40 , pp. 179-187
    • Yoshizawa, K.1    Abe, H.2    Kubo, Y.3
  • 28
    • 77449095704 scopus 로고    scopus 로고
    • Expression of master regulators of helper T-cell differentiation in peripheral T-cell lymphoma, not otherwise specified, by immunohistochemical analysis
    • Matsumoto Y., Horiike S., Ohshiro M., et al. Expression of master regulators of helper T-cell differentiation in peripheral T-cell lymphoma, not otherwise specified, by immunohistochemical analysis. Am J Clin Pathol 2010, 133:281-290.
    • (2010) Am J Clin Pathol , vol.133 , pp. 281-290
    • Matsumoto, Y.1    Horiike, S.2    Ohshiro, M.3
  • 29
    • 70449411040 scopus 로고    scopus 로고
    • Enhanced ability of regulatory T cells in chronic hepatitis C patients with persistently normal alanine aminotransferase levels than those with active hepatitis
    • Itose I., Kanto T., Kakita N., et al. Enhanced ability of regulatory T cells in chronic hepatitis C patients with persistently normal alanine aminotransferase levels than those with active hepatitis. J Viral Hepat 2009, 16:844-852.
    • (2009) J Viral Hepat , vol.16 , pp. 844-852
    • Itose, I.1    Kanto, T.2    Kakita, N.3
  • 30
    • 33745323050 scopus 로고    scopus 로고
    • Circulating and liver resident CD4+CD25+ regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B
    • Xu D., Fu J., Jin L., et al. Circulating and liver resident CD4+CD25+ regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B. J Immunol 2006, 177:739-747.
    • (2006) J Immunol , vol.177 , pp. 739-747
    • Xu, D.1    Fu, J.2    Jin, L.3
  • 31
    • 69949109982 scopus 로고    scopus 로고
    • Abnormal hematological indices in cirrhosis
    • Qamar A.A., Grace N.D. Abnormal hematological indices in cirrhosis. Can J Gastroenterol 2009, 23:441-445.
    • (2009) Can J Gastroenterol , vol.23 , pp. 441-445
    • Qamar, A.A.1    Grace, N.D.2
  • 32
    • 33846985915 scopus 로고    scopus 로고
    • Immunopathogenesis in hepatitis C virus cirrhosis
    • Spengler U., Nattermann J. Immunopathogenesis in hepatitis C virus cirrhosis. Clin Sci (Lond) 2007, 112:141-155.
    • (2007) Clin Sci (Lond) , vol.112 , pp. 141-155
    • Spengler, U.1    Nattermann, J.2
  • 33
    • 0031024392 scopus 로고    scopus 로고
    • Semiquantitative analysis of intrahepatic cytokine mRNAs in chronic hepatitis C
    • Dumoulin F.L., Bach A., Leifeld L., et al. Semiquantitative analysis of intrahepatic cytokine mRNAs in chronic hepatitis C. J Infect Dis 1997, 175:681-685.
    • (1997) J Infect Dis , vol.175 , pp. 681-685
    • Dumoulin, F.L.1    Bach, A.2    Leifeld, L.3
  • 34
    • 0029810790 scopus 로고    scopus 로고
    • Progressive liver injury in chronic hepatitis C infection correlates with increased intrahepatic expression of Th1-associated cytokines
    • Napoli J., Bishop G.A., McGuinness P.H., et al. Progressive liver injury in chronic hepatitis C infection correlates with increased intrahepatic expression of Th1-associated cytokines. Hepatology 1996, 24:759-765.
    • (1996) Hepatology , vol.24 , pp. 759-765
    • Napoli, J.1    Bishop, G.A.2    McGuinness, P.H.3
  • 35
    • 77957926607 scopus 로고    scopus 로고
    • HCV+ hepatocytes induce human regulatory CD4+ T cells through the production of TGF-beta
    • Hall C.H., Kassel R., Tacke R.S., et al. HCV+ hepatocytes induce human regulatory CD4+ T cells through the production of TGF-beta. PLoS One 2010, 5:e12154.
    • (2010) PLoS One , vol.5
    • Hall, C.H.1    Kassel, R.2    Tacke, R.S.3
  • 36
    • 75149139029 scopus 로고    scopus 로고
    • Virus blocks interferon effector function by inducing protein kinase R phosphorylation
    • Garaigorta U., Chisari F.V., Hepatitis C virus blocks interferon effector function by inducing protein kinase R phosphorylation. Cell Host Microbe 2009, 6:513-522.
    • (2009) Cell Host Microbe , vol.6 , pp. 513-522
    • Garaigorta, U.1    Chisari, F.V.2    Hepatitis, C.3
  • 37
    • 17644444485 scopus 로고    scopus 로고
    • Analysis of successful immune responses in persons infected with hepatitis C virus
    • Lechner F., Wong D.K., Dunbar P.R., et al. Analysis of successful immune responses in persons infected with hepatitis C virus. J Exp Med 2000, 191:1499-1512.
    • (2000) J Exp Med , vol.191 , pp. 1499-1512
    • Lechner, F.1    Wong, D.K.2    Dunbar, P.R.3
  • 38
    • 0037105567 scopus 로고    scopus 로고
    • Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection
    • Wedemeyer H., He X.S., Nascimbeni M., et al. Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection. J Immunol 2002, 169:3447-3458.
    • (2002) J Immunol , vol.169 , pp. 3447-3458
    • Wedemeyer, H.1    He, X.S.2    Nascimbeni, M.3
  • 39
    • 0035138173 scopus 로고    scopus 로고
    • Enhanced expression of interferon-regulated genes in the liver of patients with chronic hepatitis C virus infection: detection by suppression-subtractive hybridization
    • Patzwahl R., Meier V., Ramadori G., et al. Enhanced expression of interferon-regulated genes in the liver of patients with chronic hepatitis C virus infection: detection by suppression-subtractive hybridization. J Virol 2001, 75:1332-1338.
    • (2001) J Virol , vol.75 , pp. 1332-1338
    • Patzwahl, R.1    Meier, V.2    Ramadori, G.3
  • 40
    • 0033127626 scopus 로고    scopus 로고
    • The mouse interferon-gamma transgene chronic hepatitis model (review)
    • Okamoto T., Yamamura K., Hino O. The mouse interferon-gamma transgene chronic hepatitis model (review). Int J Mol Med 1999, 3:517-520.
    • (1999) Int J Mol Med , vol.3 , pp. 517-520
    • Okamoto, T.1    Yamamura, K.2    Hino, O.3


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