Semiquantitative analysis of intrahepatic cytokine mRNAs in chronic hepatitis C

Journal of Infectious Diseases

Volumn 175, Issue 3, 1997, Pages 681-685

  Dumoulin, F L ^a   Bach, A ^a   Leifeld, L ^a   El Bakri, M ^a   Fischer, H P ^a   Sauerbruch, T ^a   Spengler, U ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; MESSENGER RNA;

ANTIVIRAL ACTIVITY; ARTICLE; BILIARY CIRRHOSIS; CLINICAL ARTICLE; CONTROLLED STUDY; HEPATITIS B; HEPATITIS C; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS;

EID: 0031024392     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/175.3.681     Document Type: Article

References (15)

1. Alter HJ. To C or not to C: these are the questions. Blood 1995;85:1681-5.
2. Cerny A, Chisari FV. Immunological aspects of HCV infection. Intervirology 1994;37:119-25.
3. Sher A, Gazzinelli RT, Oswald IP, et al. Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection. Immunol Rev 1992;127:183-204.
4. Mosmann TR, Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol Today 1996;17:138-46.
5. + T cells specific for the protein NS4 of hepatitis C virus in patients with chronic hepatitis C. J Exp Med 1993;178:17-25.
6. + surface phenotype and a T helper type 1 profile of cytokine secretion in the liver of patients chronically infected with hepatitis B virus. J Immunol 1994;152:3074-87.
7. Romagnani S. Lymphokine production by human T cells in disease states. Annu Rev Immunol 1994;12:227-57.
8. Knodell RG, Ishak KG, Black WC, et al. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1991;1:432-5.
9. Platzer C, Ode-Hakim S, Reinke P, Döcke WD, Ewert R, Volk HD. Quantitative PCR analysis of cytokine transcription patterns in peripheral mononuclear cells after anti-CD3 rejection therapy using two novel multispecific competitor fragments. Transplantation 1994;58:264-8.
10. Price T, Aitken J, Simpson ER. Relative expression of aromatase cytochrome p450 in human fetal tissues as determined by competitive polymerase chain reaction amplification. J Clin Endocrinol Metab 1992;74:879-83.
11. Bouaboula M, Legoux P, Pességué B, et al. Standardization of messenger RNA titration using a polymerase chain reaction method involving coamplification with a multispecific internal control. J Biol Chem 1992;267:21830-8.
12. Missale G, Rochford R, Hobbs M, et al. Cytokine messenger RNA within the liver in chronic hepatitis B virus and C virus infections [abstract]. J Hepatol 1994;20(suppl 1):S54.
13. Dumoulin FL, Düx F, Leifeld L, Herbst H, Sauerbruch T, Spengler U. Intrahepatic IL-10 mRNA in chronic liver disease [abstract]. Gastroenterology 1995;108(suppl):A1059.
14. Bertoletti A, Del Prete G, D'Elios M, et al. Different cytokine profiles of liver derived T-cell clones in chronic hepatitis B and hepatitis C virus infections [abstract D36], IX Triennial International Symposium on Viral Hepatitis, Rome, 1996.
15. Giudotti LG, Ishikawa T, Hobbs MV, Matzke B, Schreiber R, Chisari FV. Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes. Immunity 1996;4:25-6.