-
1
-
-
0035878771
-
A Phase II study of combined oral uracil and ftorafur with leucovorin for patients with squamous cell carcinoma of the head and neck
-
DOI 10.1002/1097-0142(20010715)92:2<326::AID-CNCR1326>3.0.CO;2-W
-
Colevas AD, Amrein PC, Gomolin H et al (2001) A phase II study of combined oral uracil and ftorafur with leucovorin for patients with squamous cell carcinoma of the head and neck. Cancer 92:326-331. (Pubitemid 32664438)
-
(2001)
Cancer
, vol.92
, Issue.2
, pp. 326-331
-
-
Dimitrios Colevas, A.1
Amrein, P.C.2
Gomolin, H.3
Barton, J.J.4
Read, R.R.5
Adak, S.6
Benner, S.7
Costello, R.8
Posner, M.R.9
-
2
-
-
49149083564
-
Phase II trial of neo adjuvant cisplatin, 5-fluorouracil and interferon-alpha in operable squamous cell carcinoma of the esophagus
-
Bazarbashi S, Abdelsalam M, Amin T et al (2008) Phase II trial of neo adjuvant cisplatin, 5-fluorouracil and interferon-alpha in operable squamous cell carcinoma of the esophagus. Chemotherapy 54:315-322.
-
(2008)
Chemotherapy
, vol.54
, pp. 315-322
-
-
Bazarbashi, S.1
Abdelsalam, M.2
Amin, T.3
-
3
-
-
0036057596
-
Clinical studies of three oral prodrugs of 5-fluorouracil (Capecitabine, UFT, S-1): A review
-
DOI 10.1634/theoncologist.7-4-288
-
Malet-Martino M, Martino R (2002) Clinical studies of three oral pro drugs of 5-fluorouracil (capecitabine, UFT, S-1): a review. Oncologist 7:288-323. (Pubitemid 34919955)
-
(2002)
Oncologist
, vol.7
, Issue.4
, pp. 288-323
-
-
Malet-Martino, M.1
Martino, R.2
-
4
-
-
0033770342
-
5-fluorouracil: Forty-plus and still ticking. A review of its preclinical and clinical development
-
Grem JL (2000) 5-fluorouracil: forty-plus and still ticking. A review of its preclinical and clinical development. Investig New Drugs 18:31-299.
-
(2000)
Investig New Drugs
, vol.18
, pp. 31-299
-
-
Grem, J.L.1
-
5
-
-
0032748608
-
Dihydropyrimidine dehydrogenase: Its role in 5-fluorouracil clinical toxicity and tumor resistance
-
Diasio RB, Johnson MR (1999) Dihydropyrimidine dehydrogenase: its role in 5-fluorouracil clinical toxicity and tumor resistance. Clin Cancer Res 5:2672-2673. (Pubitemid 29493937)
-
(1999)
Clinical Cancer Research
, vol.5
, Issue.10
, pp. 2672-2673
-
-
Diasio, R.B.1
Johnson, M.R.2
-
6
-
-
43449128842
-
Safety of irinotecan and infusional fluorouracil/leucovorin (FOLFIRI) in Japan: A retrospective review of 48 patients with metastatic colorectal cancer
-
DOI 10.1007/s10147-007-0737-z
-
Fuse N, Doi T, Ohtsu A et al (2008) Safety of irinotecan and infusional fluorouracil/leucovorin (FOLFIRI) in Japan: a retrospective review of 48 patients with metastatic colorectal cancer. Int J Clin Oncol 13:144-149. (Pubitemid 351668172)
-
(2008)
International Journal of Clinical Oncology
, vol.13
, Issue.2
, pp. 144-149
-
-
Fuse, N.1
Doi, T.2
Ohtsu, A.3
Yano, T.4
Hamamoto, Y.5
Minashi, K.6
Tahara, M.7
Muto, M.8
Asaka, M.9
Yoshida, S.10
-
7
-
-
0032127244
-
Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5 fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue
-
DOI 10.1016/S0959-8049(98)00058-6, PII S0959804998000586
-
Miwa M, Ura M, Nishida M et al (1998) Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5- fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue. Eur J Cancer 34:1274-1281. (Pubitemid 28342121)
-
(1998)
European Journal of Cancer
, vol.34
, Issue.8
, pp. 1274-1281
-
-
Miwa, M.1
Ura, M.2
Nishida, M.3
Sawada, N.4
Ishikawa, T.5
Mori, K.6
Shimma, N.7
Umeda, I.8
Ishitsuka, H.9
-
8
-
-
34547706002
-
A review of the role of capecitabine in the treatment of colorectal cancer
-
Comella P (2007) A review of the role of capecitabine in the treatment of colorectal cancer. Ther Clin Risk Manag 3:421-431. (Pubitemid 47214982)
-
(2007)
Therapeutics and Clinical Risk Management
, vol.3
, Issue.3
, pp. 421-431
-
-
Comella, P.1
-
9
-
-
45849103518
-
Anti-angiogenic effect of 5-fluorouracil-based drugs against human colon cancer xenograft
-
Ooyama A, Oka T, Zhao HY et al (2008) Anti-angiogenic effect of 5-fluorouracil-based drugs against human colon cancer xenograft. Cancer Lett 267:26-36.
-
(2008)
Cancer Lett
, vol.267
, pp. 26-36
-
-
Ooyama, A.1
Oka, T.2
Zhao, H.Y.3
-
10
-
-
14844303761
-
Capecitabine: A review
-
DOI 10.1016/j.clinthera.2005.01.005
-
Walko CM, Lindley C (2005) Capecitabine: a review. Clin Ther 27:23-44. (Pubitemid 40347299)
-
(2005)
Clinical Therapeutics
, vol.27
, Issue.1
, pp. 23-44
-
-
Walko, C.M.1
Lindley, C.2
-
11
-
-
0031671094
-
Phase I and pharmacologic study of intermittent twice-daily oral therapy with capecitabine in patients with advanced and/or metastatic cancer
-
Mackean M, Planting A, Twelves C et al (1998) Phase I and pharmacologic study of intermittent twice-daily oral therapy with capecitabine in patients with advanced and/or metastatic cancer. J Clin Oncol 16:2977-2985. (Pubitemid 28417417)
-
(1998)
Journal of Clinical Oncology
, vol.16
, Issue.9
, pp. 2977-2985
-
-
Mackean, M.1
Planting, A.2
Twelves, C.3
Schellens, J.4
Allman, D.5
Osterwalder, B.6
Reigner, B.7
Griffin, T.8
Kaye, S.9
Verweij, J.10
-
12
-
-
10744232035
-
Phase I and pharmacokinetic study of the association of capecitabine-cisplatin in head and neck cancer patients
-
DOI 10.1093/annonc/mdg410
-
Pivot X, Chamorey E, Guardiola E et al (2003) Phase I and pharmacokinetic study of the association of capecitabine-cisplatin in head and neck cancer patients. Ann Oncol 14:1578-1586. (Pubitemid 37304616)
-
(2003)
Annals of Oncology
, vol.14
, Issue.10
, pp. 1578-1586
-
-
Pivot, X.1
Chamorey, E.2
Guardiola, E.3
Magne, N.4
Thyss, A.5
Otto, J.6
Giroux, B.7
Mouri, Z.8
Schneider, M.9
Milano, G.10
-
13
-
-
0035987216
-
Capecitabine (Xeloda ™) in combination with oxaliplatin: A phase I, dose-escalation study in patients with advanced or metastatic solid tumors
-
DOI 10.1093/annonc/mdf065
-
Diaz-Rubio E, Evans TR, Tabernero J et al (2002) Capecitabine (Xeloda) in combination with oxaliplatin: a phase I dose-escalation study in patients with advanced or metastatic solid tumors. Ann Oncol 13:558-565. (Pubitemid 34461139)
-
(2002)
Annals of Oncology
, vol.13
, Issue.4
, pp. 558-565
-
-
Diaz-Rubio, E.1
Evans, T.R.J.2
Tabernero, J.3
Cassidy, J.4
Sastre, J.5
Eatock, M.6
Bisset, D.7
Regueiro, P.8
Baselga, J.9
-
14
-
-
50249111676
-
Phase I study of vorinostat (VOR) in combination with capecitabine (CAP) in patients (pts) with advanced solid tumors
-
Tang p, Oza A, Townsley C et al (2007) Phase I study of vorinostat (VOR) in combination with capecitabine (CAP) in patients (pts) with advanced solid tumors. J Clin Oncol 25:3576.
-
(2007)
J Clin Oncol
, vol.25
, pp. 3576
-
-
Tang, P.1
Oza, A.2
Townsley, C.3
-
15
-
-
0034079455
-
A phase I and pharmacokinetic study of the combination of capecitabine and docetaxel in patients with advanced solid tumours
-
Pronk LC, Vasey P, Sparreboom A et al (2000) A phase I and pharmacokinetic study of the combination of capecitabine and docetaxel in patients with advanced solid tumours. Br J Cancer 83:22-29. (Pubitemid 30352712)
-
(2000)
British Journal of Cancer
, vol.83
, Issue.1
, pp. 22-29
-
-
Pronk, L.C.1
Vasey, P.2
Sparreboom, A.3
Reigner, B.4
Planting, A.S.Th.5
Gordon, R.J.6
Osterwalder, B.7
Verweij, J.8
Twelves, C.9
-
16
-
-
0033040540
-
Phase I and pharmacokinetic study of the oral fluoropyrimidine capecitabine in combination with paclitaxel in patients with advanced solid malignancies
-
Villalona-Calero MA, Weiss GR, Burris HA et al (1999) Phase I and pharmacokinetic study of the oral fluoropyrimidine capecitabine in combination with paclitaxel in patients with advanced solid malignancies. J Clin Oncol 17:1915-1925. (Pubitemid 29269265)
-
(1999)
Journal of Clinical Oncology
, vol.17
, Issue.6
, pp. 1915-1925
-
-
Villalona-Calero, M.A.1
Weiss, G.R.2
Burris, H.A.3
Kraynak, M.4
Rodrigues, G.5
Drengler, R.L.6
Eckhardt, S.G.7
Reigner, B.8
Moczygemba, J.9
Burger, H.U.10
Griffin, T.11
Von Hoff, D.D.12
Rowinsky, E.K.13
-
17
-
-
42549151234
-
Capecitabine monotherapy for recurrent and metastatic nasopharyngeal cancer
-
DOI 10.1093/jjco/hyn022
-
Chua D, Wei WI, Sham JS et al (2008) Capecitabine monotherapy for recurrent and metastatic nasopharyngeal cancer. Jpn J Clin Oncol 38:244-249. (Pubitemid 351583987)
-
(2008)
Japanese Journal of Clinical Oncology
, vol.38
, Issue.4
, pp. 244-249
-
-
Chua, D.1
Wei, W.I.2
Sham, J.S.T.3
Au, G.K.H.4
-
18
-
-
34547658177
-
A phase I and pharmacokinetic study of irofulven and capecitabine administered every 2 weeks in patients with advanced solid tumors
-
DOI 10.1007/s10637-007-9071-6
-
Alexandre J, Kahatt C, Bertheault-Cvitkovic F et al (2007) A phase I and pharmacokinetic study of irofulven and capecitabine administered every 2 weeks in patients with advanced solid tumors. Invest New Drugs 25:453-462. (Pubitemid 47222915)
-
(2007)
Investigational New Drugs
, vol.25
, Issue.5
, pp. 453-462
-
-
Alexandre, J.1
Kahatt, C.2
Bertheault-Cvitkovic, F.3
Faivre, S.4
Shibata, S.5
Hilgers, W.6
Goldwasser, F.7
Lokiec, F.8
Raymond, E.9
Weems, G.10
Shah, A.11
MacDonald, J.R.12
Cvitkovic, E.13
-
19
-
-
44949136484
-
Phase I dose escalation study with irinotecan, capecitabine, epirubicin, and granulocyte colony-stimulating factor support for patients with solid malignancies
-
Becerra BC, Verma UN, Tran HT et al (2008) Phase I dose escalation study with irinotecan, capecitabine, epirubicin, and granulocyte colony-stimulating factor support for patients with solid malignancies. Am J Clin Oncol 31:219-225.
-
(2008)
Am J Clin Oncol
, vol.31
, pp. 219-225
-
-
Becerra, B.C.1
Verma, U.N.2
Tran, H.T.3
-
20
-
-
44649136894
-
Oxidative DNA damage following photoexcitation of daunomycin: Direct role of oxygen
-
Kainthla R, Zewail-Foote M (2008) Oxidative DNA damage following photoexcitation of daunomycin: direct role of oxygen. J Photochem Photobiol A 198:200-204.
-
(2008)
J Photochem Photobiol A
, vol.198
, pp. 200-204
-
-
Kainthla, R.1
Zewail-Foote, M.2
-
21
-
-
0023919963
-
A simple technique for quantification of low levels of DNA damage in individual cells
-
Singh NP, McCoy T, Tice RR et al (1998) A simple technique for quantification of low levels of DNA damage in individual cells. Exp Cell Res 175:184-192.
-
(1998)
Exp Cell Res
, vol.175
, pp. 184-192
-
-
Singh, N.P.1
McCoy, T.2
Tice, R.R.3
-
23
-
-
0037419721
-
Free radical scavengers can differentially modulate the genotoxicity of amsacrine in normal and cancer cells
-
DOI 10.1016/S1383-5718(02)00289-9, PII S1383571802002899
-
Blasiak J, Gloc E, Drzewoski J et al (2003) Free radicals scavengers can differentially modulate the genotoxicity of amsacrine in normal and cancer cells. Mutat Res 535:25-34. (Pubitemid 36120758)
-
(2003)
Mutation Research - Genetic Toxicology and Environmental Mutagenesis
, vol.535
, Issue.1
, pp. 25-34
-
-
Blasiak, J.1
Gloc, E.2
Drzewoski, J.3
Wozniak, K.4
Zadrozny, M.5
Skorski, T.6
Pertynski, T.7
-
24
-
-
0030968310
-
Microgel electrophoresis: Sensitivity, mechanisms and DNA electro stretching
-
Singh NP, Stephens RE (1997) Microgel electrophoresis: sensitivity, mechanisms and DNA electro stretching. Mutat Res 383:167-175.
-
(1997)
Mutat Res
, vol.383
, pp. 167-175
-
-
Singh, N.P.1
Stephens, R.E.2
-
25
-
-
0034037611
-
Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing
-
DOI 10.1002/(SICI)1098-2280(2000)35:3<206::AID-EM8>3.0.CO;2-J
-
Tice RR, Agurell E, Anderson D et al (2000) Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing. Environ Mol Mutagen 35:206-221. (Pubitemid 30196665)
-
(2000)
Environmental and Molecular Mutagenesis
, vol.35
, Issue.3
, pp. 206-221
-
-
Tice, R.R.1
Agurell, E.2
Anderson, D.3
Burlinson, B.4
Hartmann, A.5
Kobayashi, H.6
Miyamae, Y.7
Rojas, E.8
Ryu, J.-C.9
Sasaki, Y.F.10
-
26
-
-
0033777253
-
Investigation of the substrate spectrum of the human mismatch-specific DNA N-glycosylase MED1 (MBD4): Fundamental role of the catalytic domain
-
Petronzelli F, Riccio A, Markham GD et al (2000) Investigation of the substrate spectrum of the human mismatch-specific DNA N-glycosylase MED1 (MBD4): fundamental role of the catalytic domain. J Cell Physiol 185:473-480.
-
(2000)
J Cell Physiol
, vol.185
, pp. 473-480
-
-
Petronzelli, F.1
Riccio, A.2
Markham, G.D.3
-
27
-
-
37549072672
-
Uracil incorporation into genomic DNA does not predict toxicity caused by chemotherapeutic inhibition of thymidylate synthase
-
Luo Y, Walla M, Wyatt MD (2008) Uracil incorporation into genomic DNA does not predict toxicity caused by chemotherapeutic inhibition of thymidylate synthase. DNA Repair 7:162-169.
-
(2008)
DNA Repair
, vol.7
, pp. 162-169
-
-
Luo, Y.1
Walla, M.2
Wyatt, M.D.3
-
28
-
-
0037304541
-
Expression of uracil DNA glycosylase (UDG) does not affect cellular sensitivity to thymidylate synthase (TS) inhibition
-
DOI 10.1016/S0959-8049(02)00610-X, PII S095980490200610X
-
Welsh SJ, Hobbs S, Aherne GW (2003) Expression of uracil DNA glycosylase (UDG) does not affect cellular sensitivity to thymidylate synthase (TS) inhibition. Eur J Cancer 39:378-387. (Pubitemid 36140057)
-
(2003)
European Journal of Cancer
, vol.39
, Issue.3
, pp. 378-387
-
-
Welsh, S.J.1
Hobbs, S.2
Aherne, G.W.3
-
29
-
-
23244464739
-
Thymidylate synthase: A critical target in cancer therapy?
-
Rustum YM (2004) Thymidylate synthase: a critical target in cancer therapy? Front Biosci 9:2467-2473.
-
(2004)
Front Biosci
, vol.9
, pp. 2467-2473
-
-
Rustum, Y.M.1
|