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Angewandte Chemie - International Edition

Volumn 50, Issue 37, 2011, Pages 8714-8717

Introducing lasso peptides as molecular scaffolds for drug design: Engineering of an integrin antagonist

(8) Knappe, Thomas A a Manzenrieder, Florian b Mas Moruno, Carlos b Linne, Uwe a Sasse, Florenz d Kessler, Horst b,c Xie, Xiulan a Marahiel, Mohamed A a

a PHILIPPS UNIVERSITY MARBURG (Germany)

b TECHNICAL UNIVERSITY OF MUNICH (Germany)

c KING ABDULAZIZ UNIVERSITY (Saudi Arabia)

d HELMHOLTZ CENTRE FOR INFECTION RESEARCH (Germany)

Author keywords

drug design; epitope grafting; integrin inhibitors; lasso peptides; molecular scaffolds

Indexed keywords

DRUG DESIGN; EPITOPE GRAFTING; INTEGRINS; LASSO PEPTIDES; MOLECULAR SCAFFOLDS;

ANTIGENS; DESIGN; GRAFTING (CHEMICAL); SCAFFOLDS;

PEPTIDES;

INTEGRIN; PEPTIDE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; HUMAN; PROTEIN ENGINEERING; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

DRUG DESIGN; HUMANS; INTEGRINS; MODELS, MOLECULAR; PEPTIDES; PROTEIN ENGINEERING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 80052438940 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201102190 Document Type: Article

Times cited : (100)

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