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Volumn 32, Issue 9, 2011, Pages 1340-1348

A prolonged and exaggerated wound response with elevated ODC activity mimics early tumor development

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CXCL1 CHEMOKINE; DEXAMETHASONE; EFLORNITHINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOPEROXIDASE; ORNITHINE DECARBOXYLASE; PROTEIN KINASE B; TUMOR NECROSIS FACTOR ALPHA;

EID: 80052413599     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgr129     Document Type: Article
Times cited : (16)

References (51)
  • 1
    • 0023881236 scopus 로고
    • Polyamine metabolism and its importance in neoplastic growth as a target for chemotherapy
    • Pegg,A.E. (1988) Polyamine metabolism and its importance in neoplastic growth as a target for chemotherapy. Cancer Res., 48, 759-774.
    • (1988) Cancer Res. , vol.48 , pp. 759-774
    • Pegg, A.E.1
  • 2
    • 0017072855 scopus 로고
    • The induction of ornithine decarboxylase as an early, possibly obligatory event in mouse skin carcinogenesis
    • O'Brien,T.G. (1976) The induction of ornithine decarboxylase as an early, possibly obligatory event in mouse skin carcinogenesis. Cancer Res., 36, 2644-2653.
    • (1976) Cancer Res. , vol.36 , pp. 2644-2653
    • O'Brien, T.G.1
  • 3
    • 0023096972 scopus 로고
    • Regulation of ornithine decarboxylase gene expression in mouse epidermis and epidermal tumors during two-stage tumorigenesis
    • Gilmour,S.K. et al. (1987) Regulation of ornithine decarboxylase gene expression in mouse epidermis and epidermal tumors during two-stage tumorigenesis. Cancer Res., 47, 1221-1225.
    • (1987) Cancer Res. , vol.47 , pp. 1221-1225
    • Gilmour, S.K.1
  • 4
    • 0018879135 scopus 로고
    • Levels of activity of the polyamine biosynthetic decarboxylases as indicators of degree of malignancy of human cutaneous epitheliomas
    • Scalabrino,G. et al. (1980) Levels of activity of the polyamine biosynthetic decarboxylases as indicators of degree of malignancy of human cutaneous epitheliomas. J. Invest. Dermatol., 74, 122-124.
    • (1980) J. Invest. Dermatol. , vol.74 , pp. 122-124
    • Scalabrino, G.1
  • 5
    • 0027240083 scopus 로고
    • The ornithine decarboxylase gene is a transcriptional target of c-Myc
    • Bello-Fernandez,C. et al. (1993) The ornithine decarboxylase gene is a transcriptional target of c-Myc. Proc. Natl Acad. Sci. USA, 90, 7804-7808.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 7804-7808
    • Bello-Fernandez, C.1
  • 6
    • 0032537763 scopus 로고    scopus 로고
    • Involvement of Myc targets in c-myc and N-myc induced human tumors
    • Ben-Yosef,T. et al. (1998) Involvement of Myc targets in c-myc and N-myc induced human tumors. Oncogene, 17, 165-171.
    • (1998) Oncogene , vol.17 , pp. 165-171
    • Ben-Yosef, T.1
  • 7
    • 0027202387 scopus 로고
    • Polyamines are essential for cell transformation by pp.60v-src delineation of molecular events relevant for the transformed phenotype
    • Höltta,E. et al. (1993) Polyamines are essential for cell transformation by pp.60v-src delineation of molecular events relevant for the transformed phenotype. J. Cell Biol., 122, 903-914.
    • (1993) J. Cell Biol. , vol.122 , pp. 903-914
    • Höltta, E.1
  • 8
    • 0032125577 scopus 로고    scopus 로고
    • Ornithine decarboxylase induction in transformation by H-Ras and RhoA
    • Shantz,L. et al. (1998) Ornithine decarboxylase induction in transformation by H-Ras and RhoA. Cancer Res., 58, 2748-2753.
    • (1998) Cancer Res. , vol.58 , pp. 2748-2753
    • Shantz, L.1
  • 9
    • 0030741841 scopus 로고    scopus 로고
    • Ornithine decarboxylase overexpression is a sufficient condition for tumor promotion in mouse skin
    • O'Brien,T.G. et al. (1997) Ornithine decarboxylase overexpression is a sufficient condition for tumor promotion in mouse skin. Cancer Res., 57, 2630-2637.
    • (1997) Cancer Res. , vol.57 , pp. 2630-2637
    • O'Brien, T.G.1
  • 10
    • 0031691298 scopus 로고    scopus 로고
    • Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin
    • Smith,M.K. et al. (1998) Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin. Carcinogenesis, 19, 1409-1415.
    • (1998) Carcinogenesis , vol.19 , pp. 1409-1415
    • Smith, M.K.1
  • 11
    • 15044345723 scopus 로고    scopus 로고
    • Suprabasal induction of ornithine decarboxylase in adult mouse skin is sufficient to activate keratinocytes
    • Lan,L. et al. (2005) Suprabasal induction of ornithine decarboxylase in adult mouse skin is sufficient to activate keratinocytes. J. Invest. Dermatol., 124, 602-614.
    • (2005) J. Invest. Dermatol. , vol.124 , pp. 602-614
    • Lan, L.1
  • 12
    • 0032522797 scopus 로고    scopus 로고
    • Polyamines regulate expression of the neoplastic phenotype in mouse skin
    • Peralta Soler,A. et al. (1998) Polyamines regulate expression of the neoplastic phenotype in mouse skin. Cancer Res., 58, 1654-1659.
    • (1998) Cancer Res. , vol.58 , pp. 1654-1659
    • Peralta Soler, A.1
  • 13
    • 0034667393 scopus 로고    scopus 로고
    • Inhibition of ornithine decarboxylase (ODC) decreases tumor vascularization and reverses spontaneous tumors in ODC/Ras transgenic mice
    • Lan,L. et al. (2000) Inhibition of ornithine decarboxylase (ODC) decreases tumor vascularization and reverses spontaneous tumors in ODC/Ras transgenic mice. Cancer Res., 60, 5696-5703.
    • (2000) Cancer Res. , vol.60 , pp. 5696-5703
    • Lan, L.1
  • 14
    • 0028963615 scopus 로고
    • Role of ornithine decarboxylase in epidermal tumorigenesis
    • Clifford,A. et al. (1995) Role of ornithine decarboxylase in epidermal tumorigenesis. Cancer Res., 55, 1680-1686.
    • (1995) Cancer Res. , vol.55 , pp. 1680-1686
    • Clifford, A.1
  • 15
    • 0018954858 scopus 로고
    • Tumor promotion by abrasion induced epidermal hyperplasia in the skin of mice
    • Argyris,T.S. (1980) Tumor promotion by abrasion induced epidermal hyperplasia in the skin of mice. J. Invest. Dermatol., 75, 360-362.
    • (1980) J. Invest. Dermatol. , vol.75 , pp. 360-362
    • Argyris, T.S.1
  • 16
    • 0022891340 scopus 로고
    • Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing
    • Dvorak,H.F. (1986) Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N. Engl. J. Med., 315, 1650-1659.
    • (1986) N. Engl. J. Med. , vol.315 , pp. 1650-1659
    • Dvorak, H.F.1
  • 17
    • 0025085930 scopus 로고
    • Marjolin's ulcer: a review and reevaluation of a difficult problem
    • Fleming,M.D. et al. (1990) Marjolin's ulcer: a review and reevaluation of a difficult problem. J. Burn Care Rehabil., 11, 460-469.
    • (1990) J. Burn Care Rehabil. , vol.11 , pp. 460-469
    • Fleming, M.D.1
  • 18
    • 47749139256 scopus 로고    scopus 로고
    • Cancer as an overhealing wound: an old hypothesis revisited
    • Schafer,M. et al. (2008) Cancer as an overhealing wound: an old hypothesis revisited. Nat. Rev. Mol. Cell Biol., 9, 628-638.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 628-638
    • Schafer, M.1
  • 19
    • 0033517356 scopus 로고    scopus 로고
    • Mechanisms of disease: cutaneous wound healing
    • Singer,A.J. et al. (1999) Mechanisms of disease: cutaneous wound healing. N. Engl. J. Med., 341, 738-746.
    • (1999) N. Engl. J. Med. , vol.341 , pp. 738-746
    • Singer, A.J.1
  • 20
    • 0019123627 scopus 로고
    • Inhibition of rat skin ornithine decarboxylase by nitrofurazone
    • Lesiewicz,J. et al. (1980) Inhibition of rat skin ornithine decarboxylase by nitrofurazone. Arch. Dermatol., 116, 1225-1226.
    • (1980) Arch. Dermatol. , vol.116 , pp. 1225-1226
    • Lesiewicz, J.1
  • 21
    • 0025309346 scopus 로고
    • A study on the vital reaction in wounded skin: simultaneous determination of histamine and polyamines in injured rat skin by high-performance liquid chromatography
    • Maeno,Y. et al. (1990) A study on the vital reaction in wounded skin: simultaneous determination of histamine and polyamines in injured rat skin by high-performance liquid chromatography. Forensic Sci. Int., 46, 255-268.
    • (1990) Forensic Sci. Int. , vol.46 , pp. 255-268
    • Maeno, Y.1
  • 22
    • 0028299650 scopus 로고
    • Tumor-derived components were responsible for suppression of ornithine decarboxylase activity in the rat wounded skin
    • Abe,Y. et al. (1994) Tumor-derived components were responsible for suppression of ornithine decarboxylase activity in the rat wounded skin. J. Surg. Oncol., 55, 135-142.
    • (1994) J. Surg. Oncol. , vol.55 , pp. 135-142
    • Abe, Y.1
  • 23
    • 0034084960 scopus 로고    scopus 로고
    • Ornithine decarboxylase transgenic mice as a model for human atrichia with papular lesions
    • Panteleyev,A.A. et al. (2000) Ornithine decarboxylase transgenic mice as a model for human atrichia with papular lesions. Exp. Dermatol., 9, 146-151.
    • (2000) Exp. Dermatol. , vol.9 , pp. 146-151
    • Panteleyev, A.A.1
  • 24
    • 0020595245 scopus 로고
    • Epidermal cell cycle and transit times during hyperplastic growth induced by abrasion or treatment with 12-O-tetradecanoylphorbol-13-acetate
    • Morris,R. et al. (1983) Epidermal cell cycle and transit times during hyperplastic growth induced by abrasion or treatment with 12-O-tetradecanoylphorbol-13-acetate. Cancer Res., 43, 4935-4942.
    • (1983) Cancer Res. , vol.43 , pp. 4935-4942
    • Morris, R.1
  • 25
    • 0017659701 scopus 로고
    • Kinetics of regression of epidermal hyperplasia in the the skin of mice following abrasion
    • Argyris,T.S. (1977) Kinetics of regression of epidermal hyperplasia in the the skin of mice following abrasion. Am. J. Pathol., 88, 575-582.
    • (1977) Am. J. Pathol. , vol.88 , pp. 575-582
    • Argyris, T.S.1
  • 26
    • 0032716227 scopus 로고    scopus 로고
    • Effect of elevated levels of ornithine decarboxylase on cell cycle progression in skin
    • Gilmour,S.K. et al. (1999) Effect of elevated levels of ornithine decarboxylase on cell cycle progression in skin. Cell Growth Differ., 10, 739-748.
    • (1999) Cell Growth Differ. , vol.10 , pp. 739-748
    • Gilmour, S.K.1
  • 27
    • 0030934532 scopus 로고    scopus 로고
    • Wound-healing - aiming for perfect skin regeneration
    • Martin,P. (1997) Wound-healing - aiming for perfect skin regeneration. Science, 276, 75-81.
    • (1997) Science , vol.276 , pp. 75-81
    • Martin, P.1
  • 28
    • 0030037999 scopus 로고    scopus 로고
    • Tenascin expression during wound healing in human skin
    • Latijnhouwers,M.A. et al. (1996) Tenascin expression during wound healing in human skin. J. Pathol., 178, 30-35.
    • (1996) J. Pathol. , vol.178 , pp. 30-35
    • Latijnhouwers, M.A.1
  • 29
    • 0345256408 scopus 로고    scopus 로고
    • Tenascin-C regulates angiogenesis in tumor through the regulation of vascular endothelial growth factor expression
    • Tanaka,K. et al. (2004) Tenascin-C regulates angiogenesis in tumor through the regulation of vascular endothelial growth factor expression. Int. J. Cancer, 108, 31-40.
    • (2004) Int. J. Cancer , vol.108 , pp. 31-40
    • Tanaka, K.1
  • 30
    • 9444234506 scopus 로고    scopus 로고
    • Tissue repair and the dynamics of the extracellular matrix
    • Midwood,K.S. et al. (2004) Tissue repair and the dynamics of the extracellular matrix. Int. J. Biochem. Cell Biol., 36, 1031-1037.
    • (2004) Int. J. Biochem. Cell Biol. , vol.36 , pp. 1031-1037
    • Midwood, K.S.1
  • 31
    • 2342559981 scopus 로고    scopus 로고
    • The TOR pathway: a target for cancer therapy
    • Bjornsti,M.A. et al. (2004) The TOR pathway: a target for cancer therapy. Nat. Rev. Cancer, 4, 335-348.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 335-348
    • Bjornsti, M.A.1
  • 32
    • 33644833717 scopus 로고    scopus 로고
    • Elevated levels of ornithine decarboxylase cooperate with Raf/ERK activation to convert normal keratinocytes into invasive malignant cells
    • Hayes,C.S. et al. (2006) Elevated levels of ornithine decarboxylase cooperate with Raf/ERK activation to convert normal keratinocytes into invasive malignant cells. Oncogene, 25, 1543-1553.
    • (2006) Oncogene , vol.25 , pp. 1543-1553
    • Hayes, C.S.1
  • 33
    • 33644757915 scopus 로고    scopus 로고
    • The post-translational synthesis of a polyamine-derived amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF5A)
    • Park,M.H. (2006) The post-translational synthesis of a polyamine-derived amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF5A). J. Biochem., 139, 161-169.
    • (2006) J. Biochem. , vol.139 , pp. 161-169
    • Park, M.H.1
  • 34
    • 65549167195 scopus 로고    scopus 로고
    • Hypusine-containing protein eIF5A promotes translation elongation
    • Saini,P. et al. (2009) Hypusine-containing protein eIF5A promotes translation elongation. Nature, 459, 118-121.
    • (2009) Nature , vol.459 , pp. 118-121
    • Saini, P.1
  • 35
    • 0025400674 scopus 로고
    • Cytokine production in a model of wound healing: the appearance of MIP-1, MIP-2, cachectin/TNF and IL-1
    • Fahey,T.J.3rd et al. (1990) Cytokine production in a model of wound healing: the appearance of MIP-1, MIP-2, cachectin/TNF and IL-1. Cytokine, 2, 92-99.
    • (1990) Cytokine , vol.2 , pp. 92-99
    • Fahey 3rd., T.J.1
  • 36
    • 33847020833 scopus 로고    scopus 로고
    • Inflammation in wound repair: molecular and cellular mechanisms
    • Eming,S.A. et al. (2007) Inflammation in wound repair: molecular and cellular mechanisms. J. Invest. Dermatol., 127, 514-525.
    • (2007) J. Invest. Dermatol. , vol.127 , pp. 514-525
    • Eming, S.A.1
  • 37
    • 28644451449 scopus 로고    scopus 로고
    • Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis
    • Ito,M. et al. (2005) Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Nat. Med., 11, 1351-1354.
    • (2005) Nat. Med. , vol.11 , pp. 1351-1354
    • Ito, M.1
  • 38
    • 0022179539 scopus 로고
    • Induction of papillomas with a high probability of conversion to malignancy
    • Hennings,H. et al. (1985) Induction of papillomas with a high probability of conversion to malignancy. Carcinogenesis, 6, 1607-1610.
    • (1985) Carcinogenesis , vol.6 , pp. 1607-1610
    • Hennings, H.1
  • 39
    • 0034685624 scopus 로고    scopus 로고
    • Polyamines: mysterious modulators of cellular functions
    • Igarashi,K. et al. (2000) Polyamines: mysterious modulators of cellular functions. Biochem. Biophys. Res. Commun., 271, 559-564.
    • (2000) Biochem. Biophys. Res. Commun. , vol.271 , pp. 559-564
    • Igarashi, K.1
  • 40
    • 0031047822 scopus 로고    scopus 로고
    • Molecular mechanism of polyamine stimulation of the synthesis of oligopeptide-binding protein
    • Igarashi,K. et al. (1997) Molecular mechanism of polyamine stimulation of the synthesis of oligopeptide-binding protein. J. Biol. Chem., 272, 4058-4064.
    • (1997) J. Biol. Chem. , vol.272 , pp. 4058-4064
    • Igarashi, K.1
  • 41
    • 0035844218 scopus 로고    scopus 로고
    • Polyamine enhancement of the synthesis of adenylate cyclase at the translational level and the consequential stimulation of the synthesis of the RNA polymerase sigma 28 subunit
    • Yoshida,M. et al. (2001) Polyamine enhancement of the synthesis of adenylate cyclase at the translational level and the consequential stimulation of the synthesis of the RNA polymerase sigma 28 subunit. J. Biol. Chem., 276, 16289-16295.
    • (2001) J. Biol. Chem. , vol.276 , pp. 16289-16295
    • Yoshida, M.1
  • 42
    • 0026091913 scopus 로고
    • On the translational control of ornithine decarboxylase expression by polyamines
    • Stjernborg,L. et al. (1991) On the translational control of ornithine decarboxylase expression by polyamines. Biochim. Biophys. Acta., 8, 188-194.
    • (1991) Biochim. Biophys. Acta. , vol.8 , pp. 188-194
    • Stjernborg, L.1
  • 43
    • 0035065711 scopus 로고    scopus 로고
    • Modulation of macrophage recruitment into wounds by monocyte chemoattractant protein-1
    • Dipietro,L.A. et al. (2001) Modulation of macrophage recruitment into wounds by monocyte chemoattractant protein-1. Wound Repair Regen., 9, 28-33.
    • (2001) Wound Repair Regen. , vol.9 , pp. 28-33
    • Dipietro, L.A.1
  • 44
    • 0034888877 scopus 로고    scopus 로고
    • Wound healing in MIP-1alpha(-/-) and MCP-1(-/-) mice
    • Low,Q.E. et al. (2001) Wound healing in MIP-1alpha(-/-) and MCP-1(-/-) mice. Am. J. Pathol., 159, 457-463.
    • (2001) Am. J. Pathol. , vol.159 , pp. 457-463
    • Low, Q.E.1
  • 45
    • 65049084189 scopus 로고    scopus 로고
    • Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation
    • Mantovani,A. et al. (2009) Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation. Hum. Immunol., 70, 325-330.
    • (2009) Hum. Immunol. , vol.70 , pp. 325-330
    • Mantovani, A.1
  • 46
    • 33748808680 scopus 로고    scopus 로고
    • Reactive oxygen species and their detoxification in healing skin wounds
    • auf dem Keller,U. et al. (2006) Reactive oxygen species and their detoxification in healing skin wounds. J. Investig. Dermatol. Symp. Proc., 11, 106-111.
    • (2006) J. Investig. Dermatol. Symp. Proc. , vol.11 , pp. 106-111
    • auf dem Keller, U.1
  • 47
    • 42049084165 scopus 로고    scopus 로고
    • Elevated ornithine decarboxylase levels activate ataxia telangiectasia mutated-DNA damage signaling in normal keratinocytes
    • Wei,G. et al. (2008) Elevated ornithine decarboxylase levels activate ataxia telangiectasia mutated-DNA damage signaling in normal keratinocytes. Cancer Res., 68, 2214-2222.
    • (2008) Cancer Res. , vol.68 , pp. 2214-2222
    • Wei, G.1
  • 48
    • 33745263216 scopus 로고    scopus 로고
    • Antioxidant N-acetyl cysteine reduces incidence and multiplicity of lymphoma in Atm deficient mice
    • Reliene,R. et al. (2006) Antioxidant N-acetyl cysteine reduces incidence and multiplicity of lymphoma in Atm deficient mice. DNA Repair (Amst.), 5, 852-859.
    • (2006) DNA Repair (Amst.) , vol.5 , pp. 852-859
    • Reliene, R.1
  • 49
    • 0037449190 scopus 로고    scopus 로고
    • Properties of purified recombinant human polyamine oxidase, PAOh1/SMO
    • Wang,Y. et al. (2003) Properties of purified recombinant human polyamine oxidase, PAOh1/SMO. Biochem. Biophys. Res. Commun., 304, 605-611.
    • (2003) Biochem. Biophys. Res. Commun. , vol.304 , pp. 605-611
    • Wang, Y.1
  • 50
    • 0036389837 scopus 로고    scopus 로고
    • The polyamine oxidase inactivator MDL 72527
    • Seiler,N. et al. (2002) The polyamine oxidase inactivator MDL 72527. Prog. Drug Res., 59, 1-40.
    • (2002) Prog. Drug Res. , vol.59 , pp. 1-40
    • Seiler, N.1
  • 51
    • 78650573907 scopus 로고    scopus 로고
    • Tumor formation initiated by nondividing epidermal cells via an inflammatory infiltrate
    • Arwert,E.N. et al. (2010) Tumor formation initiated by nondividing epidermal cells via an inflammatory infiltrate. Proc. Natl Acad. Sci. USA, 107, 19903-19908.
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 19903-19908
    • Arwert, E.N.1


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