Lysine N ζ-decarboxylation switch and activation of the β-lactam sensor domain of BlaR1 protein of methicillin-resistant Staphylococcus aureus

Journal of Biological Chemistry

Volumn 286, Issue 36, 2011, Pages 31466-31472

  Borbulevych, Oleg ^a   Kumarasiri, Malika ^a   Wilson, Brian ^a   Llarrull, Leticia I ^a   Lee, Mijoon ^a   Hesek, Dusan ^a   Shi, Qicun ^a   Peng, Jeffrey ^a   Baker, Brian M ^a   Mobashery, Shahriar ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC RESISTANCE; INTEGRAL MEMBRANE PROTEINS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; NMR DATA; RECEPTOR ACTIVATION; S. AUREUS; SENSOR DOMAINS; STRUCTURAL INFORMATION; X-RAY STRUCTURE;

AMINO ACIDS; ANTIBIOTICS; BACTERIA; BINDING SITES; BIOLOGICAL MEMBRANES; CYTOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEINS; SENSORS; SIGNAL TRANSDUCTION;

CARBOXYLATION;

BETA LACTAM ANTIBIOTIC; IMIPENEM; LYSINE; MEMBRANE PROTEIN; MEROPENEM; PENICILLIN G; PROTEIN BLAR1; SERINE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; BETA LACTAM;

ACYLATION; AMINO ACID SEQUENCE; ANTIBIOTIC RESISTANCE; ARTICLE; BINDING SITE; DECARBOXYLATION; DRUG BINDING; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; X RAY CRYSTALLOGRAPHY; CHEMISTRY; METABOLISM; PROTEIN CONFORMATION;

METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS AUREUS;

BACTERIAL PROTEINS; BETA-LACTAMS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DECARBOXYLATION; LYSINE; MAGNETIC RESONANCE SPECTROSCOPY; MEMBRANE PROTEINS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; PROTEIN CONFORMATION;

EID: 80052404275     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.252189     Document Type: Article

References (43)

1. Jevons, M. P. (1961) Br. Med. J. 1, 124-125
2. Rolinson, G. N. (1961) Br. Med. J. 1, 125-126
3. Fisher, J. F., Meroueh, S. O., and Mobashery, S. (2005) Chem. Rev. 105, 395-424
4. Llarrull, L. I., Fisher, J. F., and Mobashery, S. (2009) Antimicrob. Agents Chemother. 53, 4051-4063
5. Llarrull, L. I., Testero, S. A., Fisher, J. F., and Mobashery, S. (2010) Curr. Opin. Microbiol. 13, 551-557
6. Zhang, H. Z., Hackbarth, C. J., Chansky, K. M., and Chambers, H. F. (2001) Science 291, 1962-1965
7. Llarrull, L. I., Prorok, M., and Mobashery, S. (2010) Biochemistry 49, 7975-7977
8. Thumanu, K., Cha, J., Fisher, J. F., Perrins, R., Mobashery, S., and Wharton, C. (2006) Proc. Natl. Acad. Sci. U.S.A. 103, 10630-10635
9. Golemi-Kotra, D., Cha, J. Y., Meroueh, S. O., Vakulenko, S. B., and Mobashery, S. (2003) J. Biol. Chem. 278, 18419-18425
10. Birck, C., Cha, J. Y., Cross, J., Schulze-Briese, C., Meroueh, S. O., Schlegel, H. B., Mobashery, S., and Samama, J. P. (2004) J. Am. Chem. Soc. 126, 13945-13947
11. Wilke, M. S., Hills, T. L., Zhang, H. Z., Chambers, H. F., and Strynadka, N. C. (2004) J. Biol. Chem. 279, 47278-47287
12. Kerff, F., Charlier, P., Colombo, M. L., Sauvage, E., Brans, A., Frere, J. M., Joris, B., and Fonzé, E. (2003) Biochemistry 42, 12835-12843
13. Otwinowski, Z., and Minor, W. (1997) Methods Enzymol. 276, 307-326
14. Vagin, A., and Teplyakov, A. (1997) J. Appl. Crystallogr. 30, 1022-1025
15. Murshudov, G. N., Vagin, A. A., and Dodson, E. J. (1997) Acta Crystallogr. D Biol. Crystallogr. 53, 240-255
16. Perrakis, A., Sixma, T. K., Wilson, K. S., and Lamzin, V. S. (1997) Acta Crystallogr. D Biol. Crystallogr. 53, 448-455
17. Emsley, P., and Cowtan, K. (2004) Acta Crystallogr. D Biol. Crystallogr. 60, 2126-2132
18. McRee, D. E. (1999) J. Struct. Biol. 125, 156-165
19. Laskowski, R. A., Macarthur, M. W., Moss, D. S., and Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291
20. Vriend, G. (1990) J. Mol. Graph. 8, 52-56
21. Word, J. M., Lovell, S. C., Richardson, J. S., and Richardson, D. C. (1999) J. Mol. Biol. 285, 1735-1747
22. Marley, J., Lu, M., and Bracken, C. (2001) J. Biomol. NMR 20, 71-75
23. Salzmann, M., Pervushin, K., Wider, G., Senn, H., andWüthrich, K. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 13585-13590
24. Pervushin, K., Riek, R., Wider, G., and Wüthrich, K. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 12366-12371
25. Dayie, K. T., and Wagner, G. (1994) J. Magn. Reson. Series A. 111, 121-126
26. Kay, L. E., Torchia, D. A., and Bax, A. (1989) Biochemistry 28, 8972-8979
27. Palmer, A. G., Rance, M., and Wright, P. E. (1991) J. Am. Chem. Soc. 113, 4371-4380
28. Palmer, A. G., Skelton, N. J., Chazin, W. J., Wright, P. E., and Rance, M. (1992) Mol. Phys. 75, 699-711
29. Kay, L. E., Nicholson, L. K., Delaglio, F., Bax, A., and Torchia, D. A. (1992) J. Magn. Reson. 97, 359-375
30. Peng, J. W., and Wagner, G. (1992) Biochemistry 31, 8571-8586
31. Cooper, D. R., Boczek, T., Grelewska, K., Pinkowska, M., Sikorska, M., Zawadzki, M., and Derewenda, Z. (2007) Acta Crystallogr. D Biol. Crystallogr. 63, 636-645
32. Lipari, G., and Szabo, A. (1982) J. Am. Chem. Soc. 104, 4546-4559
33. Lipari, G., and Szabo, A. (1982) J. Am. Chem. Soc. 104, 4559-4570
34. Johnson, J. W., Gretes, M., Goodfellow, V. J., Marrone, L., Heynen, M. L., Strynadka, N. C., and Dmitrienko, G. I. (2010) J. Am. Chem. Soc. 132, 2558-2560
35. Sun, T., Nukaga, M., Mayama, K., Braswell, E. H., and Knox, J. R. (2003) Protein Sci. 12, 82-91
36. Schneider, K. D., Karpen, M. E., Bonomo, R. A., Leonard, D. A., and Powers, R. A. (2009) Biochemistry 48, 11840-11847
37. Docquier, J. D., Benvenuti, M., Calderone, V., Giuliani, F., Kapetis, D., De Luca, F., Rossolini, G. M., and Mangani, S. (2010) Antimicrob. Agents Chemother. 54, 2167-2174
38. Bou, G., Santillana, E., Sheri, A., Beceiro, A., Sampson, J. M., Kalp, M., Bethel, C. R., Distler, A. M., Drawz, S. M., Pagadala, S. R., Van den Akker, F., Bonomo, R. A., Romero, A., and Buynak, J. D. (2010) J. Am. Chem. Soc. 132, 13320-13331
39. Golemi, D., Maveyraud, L., Vakulenko, S., Samama, J. P., and Mobashery, S. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 14280-14285
40. Maveyraud, L., Golemi, D., Kotra, L. P., Tranier, S., Vakulenko, S., Mobashery, S., and Samama, J. P. (2000) Structure 8, 1289-1298
41. Docquier, J. D., Calderone, V., De Luca, F., Benvenuti, M., Giuliani, F., Bellucci, L., Tafi, A., Nordmann, P., Botta, M., Rossolini, G. M., and Mangani, S. (2009) Chem. Biol. 16, 540-547
42. Golemi, D., Maveyraud, L., Vakulenko, S., Tranier, S., Ishiwata, A., Kotra, L. P., Samama, J.-P., and Mobashery, S. (2000) J. Am. Chem. Soc. 122, 6132-6133
43. Liu, X., Fan, K., and Wang, W. (2004) Proteins 54, 491-499