Discrete steps in sensing of β-lactam antibiotics by the BlaR1 protein of the methicillin-resistant Staphylococcus aureus bacterium

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 28, 2006, Pages 10630-10635

  Thumanu, Kanjana ^a   Cha, Jooyoung ^b   Fisher, Jed F ^b   Perrins, Richard ^a   Mobashery, Shahriar ^b   Wharton, Christopher ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

Infrared spectroscopy; Receptor; Signal transduction

Indexed keywords

AMPICILLIN; BACTERIAL PROTEIN; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; CARBAMIC ACID; CARBON 13; CELL SURFACE RECEPTOR; LYSINE; PROTEIN BLAR1; SERINE; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; CONFORMATIONAL TRANSITION; DECARBOXYLATION; GENE EXPRESSION; HYDROLYSIS; INFRARED SPECTROSCOPY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ACYLATION; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BETA-LACTAMS; CARRIER PROTEINS; KINETICS; METHICILLIN RESISTANCE; PENICILLIN-BINDING PROTEINS; PROTEIN CONFORMATION; SPECTROPHOTOMETRY, INFRARED; STAPHYLOCOCCUS AUREUS; TEMPERATURE;

BACTERIA (MICROORGANISMS); METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS AUREUS;

EID: 33746039712     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0601971103     Document Type: Article

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