Resistance to β-lactam antibiotics and its mediation by the sensor domain of the transmembrane BlaR signaling pathway in Staphylococcus aureus

Journal of Biological Chemistry

Volumn 278, Issue 20, 2003, Pages 18419-18425

  Golemi Kotra, Dasantila ^a   Cha, Joo Young ^a   Meroueh, Samy O ^a   Vakulenko, Sergei B ^a   Mobashery, Shahriar ^a  

^a WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLATION; BINDING ENERGY; BIOCHEMISTRY; CELL MEMBRANES; CONFORMATIONS; ENZYME INHIBITION; GENETIC ENGINEERING; RATE CONSTANTS;

INFECTIONS;

ANTIBIOTICS;

AMPICILLIN; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; BOCILLIN FL; CEFEPIME; CEFTAZIDIME; DRUG; IMIPENEM; MEMBRANE PROTEIN; NITROCEFIN; OXACILLIN; PENICILLIN BINDING PROTEIN; PENICILLIN BINDING PROTEIN 2A; PENICILLIN DERIVATIVE; PROTEIN BLAR; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; BETA LACTAM; BLAR SENSORY TRANSDUCER PROTEIN, BACTERIA; BLAR SENSORY-TRANSDUCER PROTEIN, BACTERIA; CARBON; CARBON DIOXIDE; CARBOXYPEPTIDASE TRANSPEPTIDASE; CARRIER PROTEIN; GLYCOSYLTRANSFERASE; LYSINE; PEPTIDYLTRANSFERASE; SERINE;

ANTIBIOTIC RESISTANCE; ARTICLE; BINDING KINETICS; CARBOXYLATION; CONFORMATIONAL TRANSITION; COVALENT BOND; CYTOPLASM; DEACYLATION; DRUG MECHANISM; ENZYME ACTIVE SITE; GENE EXPRESSION REGULATION; HYDROLYSIS; INFECTION RISK; MICROSCOPIC ANATOMY; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROCESS MONITORING; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN MODIFICATION; PROTEIN PURIFICATION; SIGNAL TRANSDUCTION; STAPHYLOCOCCUS AUREUS; BINDING SITE; BIOLOGICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; CIRCULAR DICHROISM; ESCHERICHIA COLI; KINETICS; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; PH; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE;

NEGIBACTERIA; STAPHYLOCOCCI; STAPHYLOCOCCUS AUREUS;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BETA-LACTAMS; BINDING SITES; CARBON; CARBON DIOXIDE; CARRIER PROTEINS; CIRCULAR DICHROISM; CLONING, MOLECULAR; CYTOPLASM; DNA MUTATIONAL ANALYSIS; DRUG RESISTANCE, MICROBIAL; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; HEXOSYLTRANSFERASES; HYDROGEN-ION CONCENTRATION; KINETICS; LYSINE; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MURAMOYLPENTAPEPTIDE CARBOXYPEPTIDASE; PENICILLIN-BINDING PROTEINS; PEPTIDYL TRANSFERASES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SERINE; SIGNAL TRANSDUCTION; STAPHYLOCOCCUS AUREUS;

EID: 0038381513     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M300611200     Document Type: Article

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