메뉴 건너뛰기




Volumn 46, Issue 8, 2011, Pages 1020-1030

Differential alteration of CD56bright and CD56dim natural killer cells in frequency, phenotype, and cytokine response in chronic hepatitis C virus infection

Author keywords

CD56bright; CD56dim; Chronic hepatitis; HCV; NK cells

Indexed keywords

CD56 ANTIGEN; CD94 ANTIGEN; NATURAL KILLER CELL RECEPTOR NKG2A; NATURAL KILLER CELL RECEPTOR NKG2D; STAT1 PROTEIN; STAT4 PROTEIN;

EID: 80052403740     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-011-0408-8     Document Type: Article
Times cited : (7)

References (44)
  • 1
    • 0033009888 scopus 로고    scopus 로고
    • Natural killer cells in antiviral defense: Function and regulation by innate cytokines
    • DOI 10.1146/annurev.immunol.17.1.189
    • CA Biron KB Nguyen GC Pien LP Cousens TP Salazar-Mather 1999 Natural killer cells in antiviral defense: function and regulation by innate cytokines Annu Rev Immunol 17 189 220 10358757 10.1146/annurev.immunol.17.1.189 1:CAS:528:DyaK1MXjtVSrtbo%3D (Pubitemid 29241123)
    • (1999) Annual Review of Immunology , vol.17 , pp. 189-220
    • Biron, C.A.1    Nguyen, K.B.2    Pien, G.C.3    Cousens, L.P.4    Salazar-Mather, T.P.5
  • 2
    • 0027411525 scopus 로고
    • The molecular cell biology of interferon-γ and its receptor
    • MA Farrar RD Schreiber 1993 The molecular cell biology of interferon-gamma and its receptor Annu Rev Immunol 11 571 611 8476573 10.1146/annurev.iy.11.040193.003035 1:CAS:528:DyaK3sXktVKlsrg%3D (Pubitemid 23115018)
    • (1993) Annual Review of Immunology , vol.11 , pp. 571-611
    • Farrar, M.A.1    Schreiber, R.D.2
  • 3
    • 34249310719 scopus 로고    scopus 로고
    • Keeping NK cells in highly regulated antiviral warfare
    • DOI 10.1016/j.it.2007.04.001, PII S1471490607000816
    • SH Lee T Miyagi CA Biron 2007 Keeping NK cells in highly regulated antiviral warfare Trends Immunol. 28 252 259 17466596 10.1016/j.it.2007.04.001 1:CAS:528:DC%2BD2sXmtVGgtL8%3D (Pubitemid 46810349)
    • (2007) Trends in Immunology , vol.28 , Issue.6 , pp. 252-259
    • Lee, S.-H.1    Miyagi, T.2    Biron, C.A.3
  • 4
    • 0035499063 scopus 로고    scopus 로고
    • The biology of human natural killer-cell subsets
    • DOI 10.1016/S1471-4906(01)02060-9, PII S1471490601020609
    • MA Cooper TA Fehniger MA Caligiuri 2001 The biology of human natural killer-cell subsets Trends Immunol. 22 633 640 11698225 10.1016/S1471-4906(01) 02060-9 1:CAS:528:DC%2BD3MXot1Siuro%3D (Pubitemid 33043908)
    • (2001) Trends in Immunology , vol.22 , Issue.11 , pp. 633-640
    • Cooper, M.A.1    Fehniger, T.A.2    Caligiuri, M.A.3
  • 5
    • 50949124847 scopus 로고    scopus 로고
    • Human natural killer cells
    • 18650461 10.1182/blood-2007-09-077438 1:CAS:528:DC%2BD1cXpsVajtb0%3D
    • MA Caligiuri 2008 Human natural killer cells Blood 112 461 469 18650461 10.1182/blood-2007-09-077438 1:CAS:528:DC%2BD1cXpsVajtb0%3D
    • (2008) Blood , vol.112 , pp. 461-469
    • Caligiuri, M.A.1
  • 6
    • 0034651580 scopus 로고    scopus 로고
    • Pathogenesis, natural history, treatment, and prevention of hepatitis C
    • TJ Liang B Rehermann LB Seeff JH Hoofnagle 2000 Pathogenesis, natural history, treatment, and prevention of hepatitis C Ann Intern Med 132 296 305 10681285 1:CAS:528:DC%2BD3cXhtlyku7g%3D (Pubitemid 30106261)
    • (2000) Annals of Internal Medicine , vol.132 , Issue.4 , pp. 296-305
    • Liang, T.J.1    Rehermann, B.2    Seeff, L.B.3    Hoofnagle, J.H.4
  • 8
    • 0035934568 scopus 로고    scopus 로고
    • Peginterferon alfa-2b plus ribavirin compared with interferonalfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial
    • DOI 10.1016/S0140-6736(01)06102-5
    • MP Manns JG McHutchison SC Gordon VK Rustgi M Shiffman R Reindollar, et al. 2001 Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial Lancet 358 958 965 11583749 10.1016/S0140-6736(01)06102-5 1:CAS:528: DC%2BD3MXntF2qtb8%3D (Pubitemid 32913521)
    • (2001) Lancet , vol.358 , Issue.9286 , pp. 958-965
    • Manns, M.P.1    McHutchison, J.G.2    Gordon, S.C.3    Rustgi, V.K.4    Shiffman, M.5    Reindollar, R.6    Goodman, Z.D.7    Koury, K.8    Ling, M.-H.9    Albrecht, J.K.10
  • 9
    • 0037179698 scopus 로고    scopus 로고
    • Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection
    • 12324553 10.1056/NEJMoa020047 1:CAS:528:DC%2BD38Xnt12rtb0%3D
    • MW Fried ML Shiffman KR Reddy C Smith G Marinos FL Gonçales Jr, et al. 2002 Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection N Engl J Med 347 975 982 12324553 10.1056/NEJMoa020047 1:CAS:528:DC%2BD38Xnt12rtb0%3D
    • (2002) N Engl J Med , vol.347 , pp. 975-982
    • Fried, M.W.1    Shiffman, M.L.2    Reddy, K.R.3    Smith, C.4    Marinos, G.5    Gonçales Jr., F.L.6
  • 10
    • 13844270879 scopus 로고    scopus 로고
    • Efficacy of a 24-week course of PEG-interferon α-2b monotherapy in patients with acute hepatitis C after failure of spontaneous clearance
    • DOI 10.1016/j.jhep.2004.11.021
    • T Santantonio M Fasano E Sinisi A Guastadisegni C Casalino M Mazzola, et al. 2005 Efficacy of a 24-week course of PEG-interferon alpha-2b monotherapy in patients with acute hepatitis C after failure of spontaneous clearance J Hepatol 42 329 333 15710214 10.1016/j.jhep.2004.11.021 1:CAS:528:DC%2BD2MXhtlensrs%3D (Pubitemid 40254246)
    • (2005) Journal of Hepatology , vol.42 , Issue.3 , pp. 329-333
    • Santantonio, T.1    Fasano, M.2    Sinisi, E.3    Guastadisegni, A.4    Casalino, C.5    Mazzola, M.6    Francavilla, R.7    Pastore, G.8
  • 12
    • 33645231470 scopus 로고    scopus 로고
    • Decreased NK cell frequency in chronic hepatitis C does not affect ex vivo cytolytic killing
    • 16496327 10.1002/hep.21073
    • C Morishima DM Paschal CC Wang CS Yoshihara BL Wood AE Yeo, et al. 2006 Decreased NK cell frequency in chronic hepatitis C does not affect ex vivo cytolytic killing Hepatology. 43 573 580 16496327 10.1002/hep.21073
    • (2006) Hepatology. , vol.43 , pp. 573-580
    • Morishima, C.1    Paschal, D.M.2    Wang, C.C.3    Yoshihara, C.S.4    Wood, B.L.5    Yeo, A.E.6
  • 13
    • 33646810822 scopus 로고    scopus 로고
    • Surface expression and cytolytic function of natural killer cell receptors is altered in chronic hepatitis C
    • DOI 10.1136/gut.2005.076463
    • J Nattermann G Feldmann G Ahlenstiel B Langhans T Sauerbruch U Spengler 2006 Surface expression and cytolytic function of natural killer cell receptors is altered in chronic hepatitis C Gut. 55 869 877 16322112 10.1136/gut.2005. 076463 1:CAS:528:DC%2BD28XlvVOhtLw%3D (Pubitemid 43764560)
    • (2006) Gut , vol.55 , Issue.6 , pp. 869-877
    • Nattermann, J.1    Feldmann, G.2    Ahlenstiel, G.3    Langhans, B.4    Sauerbruch, T.5    Spengler, U.6
  • 14
    • 48249137638 scopus 로고    scopus 로고
    • Altered natural killer cell subset distributions in resolved and persistent hepatitis C virus infection following single source exposure
    • 18372499 10.1136/gut.2007.130963 1:STN:280:DC%2BD1cvltFWgtg%3D%3D
    • L Golden-Mason L Madrigal-Estebas E McGrath MJ Conroy EJ Ryan JE Hegarty, et al. 2008 Altered natural killer cell subset distributions in resolved and persistent hepatitis C virus infection following single source exposure Gut. 57 1121 1128 18372499 10.1136/gut.2007.130963 1:STN:280:DC%2BD1cvltFWgtg%3D%3D
    • (2008) Gut. , vol.57 , pp. 1121-1128
    • Golden-Mason, L.1    Madrigal-Estebas, L.2    McGrath, E.3    Conroy, M.J.4    Ryan, E.J.5    Hegarty, J.E.6
  • 15
    • 68049142973 scopus 로고    scopus 로고
    • Fine characterization of intrahepatic NK cells expressing natural killer receptors in chronic hepatitis B and C
    • 19596474 10.1016/j.jhep.2009.05.030 1:CAS:528:DC%2BD1MXpsFyhsrk%3D
    • P Bonorino M Ramzan X Camous T Dufeu-Duchesne MA Thélu N Sturm, et al. 2009 Fine characterization of intrahepatic NK cells expressing natural killer receptors in chronic hepatitis B and C J Hepatol 51 458 467 19596474 10.1016/j.jhep.2009.05.030 1:CAS:528:DC%2BD1MXpsFyhsrk%3D
    • (2009) J Hepatol , vol.51 , pp. 458-467
    • Bonorino, P.1    Ramzan, M.2    Camous, X.3    Dufeu-Duchesne, T.4    Thélu, M.A.5    Sturm, N.6
  • 16
    • 69249113887 scopus 로고    scopus 로고
    • Natural killer cell functional dichotomy in chronic hepatitis B and chronic hepatitis C virus infections
    • 1160.e1-7
    • Oliviero B, Varchetta S, Paudice E, Michelone G, Zaramella M, Mavilio D, et al. Natural killer cell functional dichotomy in chronic hepatitis B and chronic hepatitis C virus infections. Gastroenterology. 2009;137:1151-60, 1160.e1-7.
    • (2009) Gastroenterology , vol.137 , pp. 1151-1160
    • Oliviero, B.1    Varchetta, S.2    Paudice, E.3    Michelone, G.4    Zaramella, M.5    Mavilio, D.6
  • 17
    • 26444463119 scopus 로고    scopus 로고
    • Natural killer cells in hepatitis C virus infection: From innate immunity to adaptive immunity
    • DOI 10.1016/S1542-3565(05)00702-0, PII S1542356505007020
    • T Takehara N Hayashi 2005 Natural killer cells in hepatitis C virus infection: from innate immunity to adaptive immunity Clin Gastroenterol Hepatol. 3 S78 S81 16234066 10.1016/S1542-3565(05)00702-0 1:CAS:528:DC%2BD2MXhtF2ms7zP (Pubitemid 41427733)
    • (2005) Clinical Gastroenterology and Hepatology , vol.3 , Issue.SUPPL. 2
    • Takehara, T.1    Hayashi, N.2
  • 18
    • 33645297935 scopus 로고    scopus 로고
    • Natural killer cells: Primary target for hepatitis C virus immune evasion strategies?
    • 16498647 10.1002/lt.20708
    • L Golden-Mason HR Rosen 2006 Natural killer cells: primary target for hepatitis C virus immune evasion strategies? Liver Transpl. 12 363 372 16498647 10.1002/lt.20708
    • (2006) Liver Transpl. , vol.12 , pp. 363-372
    • Golden-Mason, L.1    Rosen, H.R.2
  • 19
    • 36348973582 scopus 로고    scopus 로고
    • Altered innate immunity in chronic hepatitis C infection: Cause or effect?
    • DOI 10.1002/hep.21938
    • G Szabo S Chang A Dolganiuc 2007 Altered innate immunity in chronic hepatitis C infection: cause or effect? Hepatology. 46 1279 1290 17886338 10.1002/hep.21938 1:CAS:528:DC%2BD2sXht1aksrvL (Pubitemid 350144792)
    • (2007) Hepatology , vol.46 , Issue.4 , pp. 1279-1290
    • Szabo, G.1    Chang, S.2    Dolganiuc, A.3
  • 20
    • 0029778988 scopus 로고    scopus 로고
    • An algorithm for the grading of activity in chronic hepatitis C
    • DOI 10.1053/jhep.1996.v24.pm0008690394
    • P Bedossa T Poynard 1996 An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group Hepatology. 24 289 293 8690394 10.1002/hep.510240201 1:STN:280:DyaK28zhvFClug%3D%3D (Pubitemid 26260021)
    • (1996) Hepatology , vol.24 , Issue.2 , pp. 289-293
    • Bedossa, P.1    Poynard, T.2
  • 21
    • 8444242871 scopus 로고    scopus 로고
    • Negative regulation of NK cell activities by inhibitory receptor CD94/NKG2A leads to altered NK cell-induced modulation of dendritic cell functions in chronic hepatitis C virus infection
    • M Jinushi T Takehara T Tatsumi T Kanto T Miyagi T Suzuki, et al. 2004 Negative regulation of NK cell activities by inhibitory receptor CD94/NKG2A leads to altered NK cell-induced modulation of dendritic cell functions in chronic hepatitis C virus infection J Immunol 173 6072 6081 15528343 1:CAS:528:DC%2BD2cXpt1Olsrc%3D (Pubitemid 39487763)
    • (2004) Journal of Immunology , vol.173 , Issue.10 , pp. 6072-6081
    • Jinushi, M.1    Takehara, T.2    Tatsumi, T.3    Kanto, T.4    Miyagi, T.5    Suzuki, T.6    Kanazawa, Y.7    Hiramatsu, N.8    Hayashi, N.9
  • 22
    • 34948870247 scopus 로고    scopus 로고
    • High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells
    • DOI 10.1084/jem.20070401
    • T Miyagi MP Gil X Wang J Louten WM Chu CA Biron 2007 High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells J Exp Med 204 2383 2396 17846149 10.1084/jem.20070401 1:CAS:528:DC%2BD2sXhtFCntrbN (Pubitemid 47529324)
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.10 , pp. 2383-2396
    • Miyagi, T.1    Gil, M.P.2    Wang, X.3    Louten, J.4    Chu, W.-M.5    Biron, C.A.6
  • 23
    • 77449088635 scopus 로고    scopus 로고
    • Intracellular staining for analysis of the expression and phosphorylation of signal transducers and activators of transcription (STATs) in NK cells
    • 20033640 10.1007/978-1-60761-362-6-11 1:CAS:528:DC%2BC3cXovVKjtbc%3D
    • T Miyagi SH Lee CA Biron 2010 Intracellular staining for analysis of the expression and phosphorylation of signal transducers and activators of transcription (STATs) in NK cells Methods Mol Biol 612 159 175 20033640 10.1007/978-1-60761-362-6-11 1:CAS:528:DC%2BC3cXovVKjtbc%3D
    • (2010) Methods Mol Biol , vol.612 , pp. 159-175
    • Miyagi, T.1    Lee, S.H.2    Biron, C.A.3
  • 24
    • 77955848019 scopus 로고    scopus 로고
    • Altered interferon-alpha-signaling in natural killer cells from patients with chronic hepatitis C virus infection
    • 20554341 10.1016/j.jhep.2010.03.018 1:CAS:528:DC%2BC3cXhtVelurzN
    • T Miyagi T Takehara K Nishio S Shimizu K Kohga W Li, et al. 2010 Altered interferon-alpha-signaling in natural killer cells from patients with chronic hepatitis C virus infection J Hepatol 53 424 430 20554341 10.1016/j.jhep.2010. 03.018 1:CAS:528:DC%2BC3cXhtVelurzN
    • (2010) J Hepatol , vol.53 , pp. 424-430
    • Miyagi, T.1    Takehara, T.2    Nishio, K.3    Shimizu, S.4    Kohga, K.5    Li, W.6
  • 25
    • 0034874691 scopus 로고    scopus 로고
    • Detection of intracellular phosphorylated STAT-4 by flow cytometry
    • DOI 10.1006/clim.2001.5078
    • G Uzel DM Frucht TA Fleisher SM Holland 2001 Detection of intracellular phosphorylated STAT-4 by flow cytometry Clin Immunol. 100 270 276 11513540 10.1006/clim.2001.5078 1:CAS:528:DC%2BD3MXnsFSgsLc%3D (Pubitemid 32808377)
    • (2001) Clinical Immunology , vol.100 , Issue.3 , pp. 270-276
    • Uzel, G.1    Frucht, D.M.2    Fleisher, T.A.3    Holland, S.M.4
  • 26
    • 23444446774 scopus 로고    scopus 로고
    • Coordinate analysis of murine immune cell surface markers and intracellular phosphoproteins by flow cytometry
    • PO Krutzik MR Clutter GP Nolan 2005 Coordinate analysis of murine immune cell surface markers and intracellular phosphoproteins by flow cytometry J Immunol 175 2357 2365 16081806 1:CAS:528:DC%2BD2MXntVSru7w%3D (Pubitemid 41113845)
    • (2005) Journal of Immunology , vol.175 , Issue.4 , pp. 2357-2365
    • Krutzik, P.O.1    Clutter, M.R.2    Nolan, G.P.3
  • 28
    • 0037369731 scopus 로고    scopus 로고
    • Interferon alfa regulated gene expression in patients initiating interferon treatment for chronic hepatitis C
    • DOI 10.1053/jhep.2003.50105
    • X Ji R Cheung S Cooper Q Li HB Greenberg XS He 2003 Interferon alfa regulated gene expression in patients initiating interferon treatment for chronic hepatitis C Hepatology. 37 610 621 12601359 10.1053/jhep.2003.50105 1:CAS:528:DC%2BD3sXit1yltrc%3D (Pubitemid 36258783)
    • (2003) Hepatology , vol.37 , Issue.3 , pp. 610-621
    • Ji, X.1    Cheung, R.2    Cooper, S.3    Li, Q.4    Greenberg, H.B.5    He, X.-S.6
  • 29
    • 66749118387 scopus 로고    scopus 로고
    • The induction of type i interferon production in hepatitis C-infected patients
    • 19232000 10.1089/jir.2008.0092 1:CAS:528:DC%2BD1MXlsValu7w%3D
    • LM Pfeffer MA Madey CA Riely JF Fleckenstein 2009 The induction of type I interferon production in hepatitis C-infected patients J Interferon Cytokine Res. 29 299 306 19232000 10.1089/jir.2008.0092 1:CAS:528:DC%2BD1MXlsValu7w%3D
    • (2009) J Interferon Cytokine Res. , vol.29 , pp. 299-306
    • Pfeffer, L.M.1    Madey, M.A.2    Riely, C.A.3    Fleckenstein, J.F.4
  • 30
    • 35649007401 scopus 로고    scopus 로고
    • Viral and Host Factors Induce Macrophage Activation and Loss of Toll-Like Receptor Tolerance in Chronic HCV Infection
    • DOI 10.1053/j.gastro.2007.08.003, PII S0016508507014497
    • A Dolganiuc O Norkina K Kodys D Catalano G Bakis C Marshall, et al. 2007 Viral and host factors induce macrophage activation and loss of toll-like receptor tolerance in chronic HCV infection Gastroenterology 133 1627 1636 17916356 10.1053/j.gastro.2007.08.003 1:CAS:528:DC%2BD2sXhsVGqtrvJ (Pubitemid 350029734)
    • (2007) Gastroenterology , vol.133 , Issue.5 , pp. 1627-1636
    • Dolganiuc, A.1    Norkina, O.2    Kodys, K.3    Catalano, D.4    Bakis, G.5    Marshall, C.6    Mandrekar, P.7    Szabo, G.8
  • 31
    • 77249169773 scopus 로고    scopus 로고
    • Cell-type specific gene expression signature in liver underlies response to interferon therapy in chronic hepatitis C infection
    • 19900446 10.1053/j.gastro.2009.10.046 1:CAS:528:DC%2BC3cXksVCrtb8%3D
    • L Chen I Borozan J Sun M Guindi S Fischer J Feld, et al. 2010 Cell-type specific gene expression signature in liver underlies response to interferon therapy in chronic hepatitis C infection Gastroenterology 138 1123 1133 19900446 10.1053/j.gastro.2009.10.046 1:CAS:528:DC%2BC3cXksVCrtb8%3D
    • (2010) Gastroenterology , vol.138 , pp. 1123-1133
    • Chen, L.1    Borozan, I.2    Sun, J.3    Guindi, M.4    Fischer, S.5    Feld, J.6
  • 33
    • 33846144749 scopus 로고    scopus 로고
    • Expression profiling of peripheral-blood mononuclear cells from patients with chronic hepatitis C undergoing interferon therapy
    • DOI 10.1086/509893
    • M Tateno M Honda T Kawamura H Honda S Kaneko 2007 Expression profiling of peripheral-blood mononuclear cells from patients with chronic hepatitis C undergoing interferon therapy J Infect Dis 195 255 267 17191171 10.1086/509893 1:CAS:528:DC%2BD2sXhs1amtrY%3D (Pubitemid 46080058)
    • (2007) Journal of Infectious Diseases , vol.195 , Issue.2 , pp. 255-267
    • Tateno, M.1    Honda, M.2    Kawamura, T.3    Honda, H.4    Kaneko, S.5
  • 34
    • 33751001342 scopus 로고    scopus 로고
    • Different signaling pathways in the livers of patients with chronic hepatitis B or chronic hepatitis C
    • DOI 10.1002/hep.21383
    • M Honda T Yamashita T Ueda H Takatori R Nishino S Kaneko 2006 Different signaling pathways in the livers of patients with chronic hepatitis B or chronic hepatitis C Hepatology. 44 1122 1138 17058214 10.1002/hep.21383 1:CAS:528:DC%2BD28Xht1aktL7L (Pubitemid 44748364)
    • (2006) Hepatology , vol.44 , Issue.5 , pp. 1122-1138
    • Honda, M.1    Yamashita, T.2    Ueda, T.3    Takatori, H.4    Nishino, R.5    Kaneko, S.6
  • 35
    • 77949816250 scopus 로고    scopus 로고
    • Activation of natural killer cells during acute infection with hepatitis C virus
    • 20080094 10.1053/j.gastro.2010.01.006 1:CAS:528:DC%2BC3cXlt1Sisb4%3D
    • B Amadei S Urbani A Cazaly P Fisicaro A Zerbini P Ahmed, et al. 2010 Activation of natural killer cells during acute infection with hepatitis C virus Gastroenterology 138 1536 1545 20080094 10.1053/j.gastro.2010.01.006 1:CAS:528:DC%2BC3cXlt1Sisb4%3D
    • (2010) Gastroenterology , vol.138 , pp. 1536-1545
    • Amadei, B.1    Urbani, S.2    Cazaly, A.3    Fisicaro, P.4    Zerbini, A.5    Ahmed, P.6
  • 37
    • 11844285731 scopus 로고    scopus 로고
    • Cutting edge: Role of STAT1, STAT3, and STAT5 in IFN-αβ responses in T lymphocytes
    • Y Tanabe T Nishibori L Su RM Arduini DP Baker M David 2005 Cutting edge: role of STAT1, STAT3, and STAT5 in IFN-alpha beta responses in T lymphocytes J Immunol 174 609 613 15634877 1:CAS:528:DC%2BD2MXotV2q (Pubitemid 40094251)
    • (2005) Journal of Immunology , vol.174 , Issue.2 , pp. 609-613
    • Tanabe, Y.1    Nishibori, T.2    Su, L.3    Arduini, R.M.4    Baker, D.P.5    David, M.6
  • 38
    • 33646555810 scopus 로고    scopus 로고
    • Type 1 interferons and the virus-host relationship: A lesson in détente
    • DOI 10.1126/science.1125676
    • A García-Sastre CA Biron 2006 Type 1 interferons and the virus-host relationship: a lesson in détente Science. 312 879 882 16690858 10.1126/science.1125676 (Pubitemid 43727313)
    • (2006) Science , vol.312 , Issue.5775 , pp. 879-882
    • Garcia-Sastre, A.1    Biron, C.A.2
  • 39
    • 0030469719 scopus 로고    scopus 로고
    • Activation of STAT4 by IL-12 and IFN-α: Evidence for the Involvement of Ligand-Induced Tyrosine and Serine Phosphorylation
    • SS Cho CM Bacon C Sudarshan RC Rees D Finbloom R Pine, et al. 1996 Activation of STAT4 by IL-12 and IFN-alpha: evidence for the involvement of ligand-induced tyrosine and serine phosphorylation J Immunol 157 4781 4789 8943379 1:CAS:528:DyaK28Xnt1Gnsrk%3D (Pubitemid 126449551)
    • (1996) Journal of Immunology , vol.157 , Issue.11 , pp. 4781-4789
    • Cho, S.S.1    Bacon, C.M.2    Sudarshan, C.3    Rees, R.C.4    Finbloom, D.5    Pine, R.6    O'Shea, J.J.7
  • 40
    • 0034939227 scopus 로고    scopus 로고
    • IFN-α and IL-18 synergistically enhance IFN-γ production in human NK cells: Differential regulation of Stat4 activation and IFN-γ gene expression by IFN-α and IL-12
    • DOI 10.1002/1521-4141(200107)31:7<2236::AID-IMMU2236>3.0.CO;2-G
    • S Matikainen A Paananen M Miettinen M Kurimoto T Timonen I Julkunen, et al. 2001 IFN-alpha and IL-18 synergistically enhance IFN-gamma production in human NK cells: differential regulation of Stat4 activation and IFN-gamma gene expression by IFN-alpha and IL-12 Eur J Immunol 31 2236 2245 11449378 10.1002/1521-4141(200107)31:7<2236::AID-IMMU2236>3.0.CO;2-G 1:CAS:528:DC%2BD3MXlsVCltLk%3D (Pubitemid 32640741)
    • (2001) European Journal of Immunology , vol.31 , Issue.7 , pp. 2236-2245
    • Matikainen, S.1    Paananen, A.2    Miettinen, M.3    Kurimoto, M.4    Timonen, T.5    Julkunen, I.6    Sareneva, T.7
  • 41
    • 1542614139 scopus 로고    scopus 로고
    • IFNα regulates NK cell cytotoxicity through STAT1 pathway
    • DOI 10.1016/S1043-4666(03)00226-6, PII S1043466603002266
    • S Liang H Wei R Sun Z Tian 2003 IFN alpha regulates NK cell cytotoxicity through STAT1 pathway Cytokine. 23 190 199 12967644 10.1016/S1043-4666(03)00226- 6 1:CAS:528:DC%2BD3sXntVGlsrw%3D (Pubitemid 38340386)
    • (2003) Cytokine , vol.23 , Issue.6 , pp. 190-199
    • Liang, S.1    Wei, H.2    Sun, R.3    Tian, Z.4
  • 42
    • 72549104093 scopus 로고    scopus 로고
    • Natural killer cells are polarized toward cytotoxicity in chronic hepatitis C in an interferon-alfa-dependent manner
    • 19747917 10.1053/j.gastro.2009.08.066 1:CAS:528:DC%2BC3cXht1ajt78%3D
    • G Ahlenstiel RH Titerence C Koh B Edlich JJ Feld Y Rotman, et al. 2010 Natural killer cells are polarized toward cytotoxicity in chronic hepatitis C in an interferon-alfa-dependent manner Gastroenterology 138 325 335 19747917 10.1053/j.gastro.2009.08.066 1:CAS:528:DC%2BC3cXht1ajt78%3D
    • (2010) Gastroenterology , vol.138 , pp. 325-335
    • Ahlenstiel, G.1    Titerence, R.H.2    Koh, C.3    Edlich, B.4    Feld, J.J.5    Rotman, Y.6
  • 43
    • 36348960622 scopus 로고    scopus 로고
    • Hepatic gene expression during treatment with peginterferon and ribavirin: Identifying molecular pathways for treatment response
    • DOI 10.1002/hep.21853
    • JJ Feld S Nanda Y Huang W Chen M Cam SN Pusek, et al. 2007 Hepatic gene expression during treatment with peginterferon and ribavirin: identifying molecular pathways for treatment response Hepatology. 46 1548 1563 17929300 10.1002/hep.21853 1:CAS:528:DC%2BD2sXhtlOiu7fL (Pubitemid 350155537)
    • (2007) Hepatology , vol.46 , Issue.5 , pp. 1548-1563
    • Feld, J.J.1    Nanda, S.2    Huang, Y.3    Chen, W.4    Cam, M.5    Pusek, S.N.6    Schweigler, L.M.7    Theodore, D.8    Zacks, S.L.9    Liang, T.J.10    Fried, M.W.11
  • 44
    • 49749111514 scopus 로고    scopus 로고
    • Serum levels of soluble major histocompatibility complex (MHC) class I-related chain A in patients with chronic liver diseases and changes during transcatheter arterial embolization for hepatocellular carcinoma
    • 18754878 10.1111/j.1349-7006.2008.00859.x 1:CAS:528:DC%2BD1cXhtFKnur%2FM
    • K Kohga T Takehara T Tatsumi K Ohkawa T Miyagi N Hiramatsu, et al. 2008 Serum levels of soluble major histocompatibility complex (MHC) class I-related chain A in patients with chronic liver diseases and changes during transcatheter arterial embolization for hepatocellular carcinoma Cancer Sci. 99 1643 1649 18754878 10.1111/j.1349-7006.2008.00859.x 1:CAS:528:DC%2BD1cXhtFKnur%2FM
    • (2008) Cancer Sci. , vol.99 , pp. 1643-1649
    • Kohga, K.1    Takehara, T.2    Tatsumi, T.3    Ohkawa, K.4    Miyagi, T.5    Hiramatsu, N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.