Keeping NK cells in highly regulated antiviral warfare

Trends in Immunology

Volumn 28, Issue 6, 2007, Pages 252-259

  Lee, Seung Hwan ^a   Miyagi, Takuya ^a   Biron, Christine A ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; LIGAND;

ANTIVIRAL ACTIVITY; ARTICLE; CELL FUNCTION; CYTOKINE PRODUCTION; CYTOTOXICITY; HUMAN; NATURAL KILLER CELL; NONHUMAN; STIMULUS; TARGET CELL; VIRUS INFECTION;

ANIMALS; CYTOKINES; HUMANS; IMMUNITY, NATURAL; KILLER CELLS, NATURAL; RECEPTORS, IMMUNOLOGIC; STAT TRANSCRIPTION FACTORS; TNF-RELATED APOPTOSIS-INDUCING LIGAND; VIRUS DISEASES;

EID: 34249310719     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.it.2007.04.001     Document Type: Article

References (60)

1. Biron C.A., et al. Natural killer cells in antiviral defense: function and regulation by innate cytokines. Annu. Rev. Immunol. 17 (1999) 189-220
2. Orange J.S. Human natural killer cell deficiencies and susceptibility to infection. Microbes Infect. 4 (2002) 1545-1558
3. Orange J.S. Human natural killer cell deficiencies. Curr. Opin. Allergy Clin. Immunol. 6 (2006) 399-409
4. Vidal S.M., and Lanier L.L. NK cell recognition of mouse cytomegalovirus-infected cells. Curr. Top. Microbiol. Immunol. 298 (2006) 183-206
5. Orange J.S., et al. Viral evasion of natural killer cells. Nat. Immunol. 3 (2002) 1006-1012
6. Nguyen K.B., et al. Coordinated and distinct roles for IFN-αβ, IL-12, and IL-15 regulation of NK cell responses to viral infection. J. Immunol. 169 (2002) 4279-4287
7. MacFarlane IV A.W., and Campbell K.S. Signal transduction in natural killer cells. Curr. Top. Microbiol. Immunol. 298 (2006) 23-57
8. Biron C.A., et al. Severe herpesvirus infections in an adolescent without natural killer cells. New Engl. J. Med. 320 (1989) 1731-1735
9. Warfield K.L., et al. Role of natural killer cells in innate protection against lethal ebola virus infection. J. Exp. Med. 200 (2004) 169-179
10. Loh J., et al. Natural killer cells utilize both perforin and gamma interferon to regulate murine cytomegalovirus infection in the spleen and liver. J. Virol. 79 (2005) 661-667
11. Orange J.S., et al. Requirement for natural killer cell-produced interferon γ in defense against murine cytomegalovirus infection and enhancement of this defense pathway by interleukin 12 administration. J. Exp. Med. 182 (1995) 1045-1056
12. Sato K., et al. Antiviral response by natural killer cells through TRAIL gene induction by IFN-α/β. Eur. J. Immunol. 31 (2001) 3138-3146
13. + T cells express both TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors but are resistant to TRAIL-mediated cytotoxicity. Blood 104 (2004) 2418-2424
14. MacMicking J., et al. Nitric oxide and macrophage function. Annu. Rev. Immunol. 15 (1997) 323-350
15. Garcia-Sastre A., and Biron C.A. Type 1 interferons and the virus-host relationship: a lesson in detente. Science 312 (2006) 879-882
16. Novelli F., and Casanova J.L. The role of IL-12, IL-23 and IFN-γ in immunity to viruses. Cytokine Growth Factor Rev. 15 (2004) 367-377
17. Lieberman J. The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal. Nat. Rev. Immunol. 3 (2003) 361-370
18. Voskoboinik I., et al. Perforin-mediated target-cell death and immune homeostasis. Nat. Rev. Immunol. 6 (2006) 940-952
19. Srivastava R.K. TRAIL/Apo-2L: mechanisms and clinical applications in cancer. Neoplasia 3 (2001) 535-546
20. Dunn C., et al. Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell-mediated liver damage. J. Exp. Med. 204 (2007) 667-680
21. Kaisho T., and Akira S. Regulation of dendritic cell function through Toll-like receptors. Curr. Mol. Med. 3 (2003) 373-385
22. Orange J.S., and Biron C.A. Characterization of early IL-12, IFN-αβ, and TNF effects on antiviral state and NK cell responses during murine cytomegalovirus infection. J. Immunol. 156 (1996) 4746-4756
23. Orange J.S., and Biron C.A. An absolute and restricted requirement for IL-12 in natural killer cell IFN-γ production and antiviral defense. Studies of natural killer and T cell responses in contrasting viral infections. J. Immunol. 156 (1996) 1138-1142
24. Louten J., et al. Type 1 IFN deficiency in the absence of normal splenic architecture during lymphocytic choriomeningitis virus infection. J. Immunol. 177 (2006) 3266-3272
25. Biron C.A., et al. Innate immunity and viral infection. In: Kaufmann A., Sher A., and Ahmed R. (Eds). Immunology of Infectious Diseases (2002), ASM Press 139-160
26. Platanias L.C. Mechanisms of type-I- and type-II-interferon-mediated signalling. Nat. Rev. Immunol. 5 (2005) 375-386
27. Nguyen K.B., et al. Interferon α/β -mediated inhibition and promotion of interferon γ: STAT1 resolves a paradox. Nat. Immunol. 1 (2000) 70-76
28. Nguyen K.B., et al. Critical role for STAT4 activation by type 1 interferons in the interferon-γ response to viral infection. Science 297 (2002) 2063-2066
29. Dupuis S., et al. Impaired response to interferon-α/β and lethal viral disease in human STAT1 deficiency. Nat. Genet. 33 (2003) 388-391
30. Shuai K., and Liu B. Regulation of JAK-STAT signalling in the immune system. Nat. Rev. Immunol. 3 (2003) 900-911
31. Liu B., et al. PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity. Nat. Immunol. 5 (2004) 891-898
32. Tanaka T., et al. SLIM is a nuclear ubiquitin E3 ligase that negatively regulates STAT signaling. Immunity 22 (2005) 729-736
33. Alexander W.S., and Hilton D.J. The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response. Annu. Rev. Immunol. 22 (2004) 503-529
34. Lanier L.L. NK cell receptors. Annu. Rev. Immunol. 16 (1998) 359-393
35. Ortaldo J.R., and Young H.A. Expression of IFN-γ upon triggering of activating Ly49D NK receptors in vitro and in vivo: costimulation with IL-12 or IL-18 overrides inhibitory receptors. J. Immunol. 170 (2003) 1763-1769
36. Andre P., et al. Comparative analysis of human NK cell activation induced by NKG2D and natural cytotoxicity receptors. Eur. J. Immunol. 34 (2004) 961-971
37. French A.R., et al. DAP12 signaling directly augments proproliferative cytokine stimulation of NK cells during viral infections. J. Immunol. 177 (2006) 4981-4990
38. Gazit R., et al. Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1. Nat. Immunol. 7 (2006) 517-523
39. Mandelboim O., et al. Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cells. Nature 409 (2001) 1055-1060
40. Smith H.R., et al. Recognition of a virus-encoded ligand by a natural killer cell activation receptor. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 8826-8831
41. Arase H., et al. Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors. Science 296 (2002) 1323-1326
42. Lee S.H., et al. Transgenic expression of the activating natural killer receptor Ly49H confers resistance to cytomegalovirus in genetically susceptible mice. J. Exp. Med. 197 (2003) 515-526
43. Voigt V., et al. Murine cytomegalovirus m157 mutation and variation leads to immune evasion of natural killer cells. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 13483-13488
44. French A.R., et al. Escape of mutant double-stranded DNA virus from innate immune control. Immunity 20 (2004) 747-756
45. Desrosiers M.P., et al. Epistasis between mouse Klra and major histocompatibility complex class I loci is associated with a new mechanism of natural killer cell-mediated innate resistance to cytomegalovirus infection. Nat. Genet. 37 (2005) 593-599
46. Stewart C.A., et al. Recognition of peptide-MHC class I complexes by activating killer immunoglobulin-like receptors. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 13224-13229
47. Khakoo S.I., and Carrington M. KIR and disease: a model system or system of models?. Immunol. Rev. 214 (2006) 186-201
48. Guma M., et al. NK cell receptors involved in the response to human cytomegalovirus infection. Curr. Top. Microbiol. Immunol. 298 (2006) 207-223
49. Lopez-Botet M., et al. Natural killer cell receptors for major histocompatibility complex class I and related molecules in cytomegalovirus infection. Tissue Antigens 63 (2004) 195-203
50. Takaki R., et al. DAP12: an adapter protein with dual functionality. Immunol. Rev. 214 (2006) 118-129
51. Sjolin H., et al. Pivotal role of KARAP/DAP12 adaptor molecule in the natural killer cell-mediated resistance to murine cytomegalovirus infection. J. Exp. Med. 195 (2002) 825-834
52. Caraux A., et al. Phospholipase C-γ2 is essential for NK cell cytotoxicity and innate immunity to malignant and virally infected cells. Blood 107 (2006) 994-1002
53. Tassi I., et al. Phospholipase C-γ2 is a critical signaling mediator for murine NK cell activating receptors. J. Immunol. 175 (2005) 749-754
54. Korbel D.S., et al. Natural killer cells and innate immunity to protozoan pathogens. Int. J. Parasitol. 34 (2004) 1517-1528
55. Leonard W.J., and O'Shea J.J. Jaks and STATs: biological implications. Annu. Rev. Immunol. 16 (1998) 293-322
56. Snyder M.R., et al. The double life of NK receptors: stimulation or co-stimulation?. Trends Immunol. 25 (2004) 25-32
57. Humphrey M.B., et al. Role of ITAM-containing adapter proteins and their receptors in the immune system and bone. Immunol. Rev. 208 (2005) 50-65
58. Spritz R.A. Genetic defects in Chediak-Higashi syndrome and the beige mouse. J. Clin. Immunol. 18 (1998) 97-105
59. Levy D.E., and Garcia-Sastre A. The virus battles: IFN induction of the antiviral state and mechanisms of viral evasion. Cytokine Growth Factor Rev. 12 (2001) 143-156
60. + NK cells in response to human cytomegalovirus-infected fibroblasts. Blood 107 (2006) 3624-3631