The 4C5 cell-impermeable anti-HSP90 antibody with anti-cancer activity, is composed of a single light chain dimer

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Sidera, Katerina ^a   El Hamidieh, Avraam ^a   Mamalaki, Avgi ^a   Patsavoudi, Evangelia ^a,b  

^a HELLENIC PASTEUR INSTITUTE   (Greece)

^b UNIVERSITY OF WEST ATTICA   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMETASTATIC AGENT; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 4C5; UNCLASSIFIED DRUG; 4C5 MONOCLONAL ANTIBODY; ANTINEOPLASTIC AGENT; HEAT SHOCK PROTEIN 90; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER CELL; CELL INVASION; CHIMERA; CONTROLLED STUDY; DRUG EFFICACY; DRUG SPECIFICITY; DRUG STRUCTURE; FEMALE; HEAVY CHAIN; IN VITRO STUDY; IN VIVO STUDY; LIGHT CHAIN; LUNG METASTASIS; METASTASIS INHIBITION; MOLECULAR CLONING; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION; ANIMAL; ANTIBODY SPECIFICITY; CANCER INVASION; CHEMISTRY; CYTOLOGY; DNA SEQUENCE; DRUG EFFECT; GENETICS; HUMAN; HYBRIDOMA; IMMUNOLOGY; LUNG; METABOLISM; METASTASIS; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PATHOLOGY; PERMEABILITY; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE; TUMOR CELL LINE;

MURINAE; MUS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; ANTINEOPLASTIC AGENTS; BASE SEQUENCE; CELL LINE, TUMOR; CLONING, MOLECULAR; FEMALE; HSP90 HEAT-SHOCK PROTEINS; HUMANS; HYBRIDOMAS; IMMUNOGLOBULIN KAPPA-CHAINS; LUNG; MICE; MOLECULAR SEQUENCE DATA; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PERMEABILITY; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; SEQUENCE ANALYSIS, DNA; SINGLE-CHAIN ANTIBODIES;

EID: 80052347245     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023906     Document Type: Article

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