-
1
-
-
0034614490
-
Signaling-2000 and beyond
-
Hunter T (2000) Signaling-2000 and beyond. Cell 100:113-127
-
(2000)
Cell
, vol.100
, pp. 113-127
-
-
Hunter, T.1
-
2
-
-
0032543959
-
Enhanced Gαq signaling: A common pathway mediates cardiac hypertrophy and apoptotic heart failure
-
DOI 10.1073/pnas.95.17.10140
-
Adams JW, Sakata Y, Davis MG, Sah VP, Wang Y, Liggett SB, Chien KR, Brown JH, Dorn GW II (1998) Enhanced Gaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure. Proc Natl Acad Sci USA 95:10140-10145 (Pubitemid 28415308)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.17
, pp. 10140-10145
-
-
Adams, J.W.1
Sakata, Y.2
Davis, M.G.3
Sah, V.P.4
Wang, Y.5
Liggett, S.B.6
Chien, K.R.7
Brown, J.H.8
Dorn II, G.W.9
-
3
-
-
0035814747
-
Differential activation of signal transduction pathways in human hearts with hypertrophy versus advanced heart failure
-
Haq S, Choukroun G, Lim H, Tymitz KM, del Monte F, Gwathmey J, Grazette L, Michael A, Hajjar R, Force T, Molkentin JD (2001) Differential activation of signal transduction pathways in human hearts with hypertrophy versus advanced heart failure. Circulation 103:670-677 (Pubitemid 32144195)
-
(2001)
Circulation
, vol.103
, Issue.5
, pp. 670-677
-
-
Haq, S.1
Choukroun, G.2
Lim, H.3
Tymitz, K.M.4
Del Monte, F.5
Gwathmey, J.6
Grazette, L.7
Michael, A.8
Hajjar, R.9
Force, T.10
Molkentin, J.D.11
-
4
-
-
76749088358
-
Pathological roles of MAPK signaling pathways in human diseases
-
Kim EK, Choi EJ (2010) Pathological roles of MAPK signaling pathways in human diseases. Biochim Biophys Acta 1802: 396-405
-
(1802)
Biochim Biophys Acta
, vol.2010
, pp. 396-405
-
-
Kim, E.K.1
Choi, E.J.2
-
5
-
-
0033179153
-
Activation of c-Jun N-terminal kinases and p38-mitogen-activated protein kinases in human heart failure secondary to ischaemic heart disease
-
DOI 10.1006/jmcc.1999.0979
-
Cook SA, Sugden PH, Clerk A (1999) Activation of c-Jun N-terminal kinases and p38-mitogen-activated protein kinases in human heart failure secondary to ischaemic heart disease. J Mol Cell Cardiol 31:1429-1434 (Pubitemid 29361110)
-
(1999)
Journal of Molecular and Cellular Cardiology
, vol.31
, Issue.8
, pp. 1429-1434
-
-
Cook, S.A.1
Sugden, P.H.2
Clerk, A.3
-
6
-
-
13344275779
-
P38 MAP kinase as a therapeutic target in cardiovascular disease
-
DOI 10.1016/j.ddstr.2004.08.024, PII S1740677304000348
-
See F, Kompa A, Krum H (2004) p38 map kinase as a therapeutic target in cardiovascular disease. Drug Discov Today Ther Strateg 1:149-154 (Pubitemid 40197621)
-
(2004)
Drug Discovery Today: Therapeutic Strategies
, vol.1
, Issue.2
, pp. 149-154
-
-
See, F.1
Kompa, A.2
Krum, H.3
-
7
-
-
0032563677
-
'Stress-responsive' mitogen-activated protein kinases (c-Jun N-terminal kinases and p38 mitogen-activated protein kinases) in the myocardium
-
Sugden PH, Clerk A (1998) "Stress-responsive" mitogen-activated protein kinases (c-Jun N-terminal kinases and p38 mitogenactivated protein kinases) in the myocardium. Circ Res 83: 345-352 (Pubitemid 28389964)
-
(1998)
Circulation Research
, vol.83
, Issue.4
, pp. 345-352
-
-
Sugden, P.H.1
Clerk, A.2
-
8
-
-
0033998888
-
Inhibition of the cardiac p38-MAPK pathway by SB203580 delays ischemic cell death
-
DOI 10.1097/00005344-200003000-00019
-
Barancik M, Htun P, Strohm C, Kilian S, Schaper W (2000) Inhibition of the cardiac p38-MAPK pathway by SB203580 delays ischemic cell death. J Cardiovasc Pharmacol 35:474-483 (Pubitemid 30127197)
-
(2000)
Journal of Cardiovascular Pharmacology
, vol.35
, Issue.3
, pp. 474-483
-
-
Barancik, M.1
Htun, P.2
Strohm, C.3
Kilian, S.4
Schaper, W.5
-
9
-
-
0035718293
-
Activation of cardiac c-Jun NH(2)-terminal kinases and p38-mitogen-activated protein kinases with abrupt changes in hemodynamic load
-
Fischer TA, Ludwig S, Flory E, Gambaryan S, Singh K, Finn P, Pfeffer MA, Kelly RA, Pfeffer JM
-
Fischer TA, Ludwig S, Flory E, Gambaryan S, Singh K, Finn P, Pfeffer MA, Kelly RA, Pfeffer JM (2001) Activation of cardiac c-Jun NH(2)-terminal kinases and p38-mitogen-activated protein kinases with abrupt changes in hemodynamic load. Hypertension 37:1222-1228
-
(2001)
Hypertension
, vol.37
, pp. 1222-1228
-
-
-
10
-
-
0037230940
-
Acute and chronic endothelial dysfunction: Implications for the development of heart failure
-
DOI 10.1023/A:1022151106019
-
Linke A, Recchia F, Zhang X, Hintze TH (2003) Acute and chronic endothelial dysfunction: implications for the development of heart failure. Heart Fail Rev 8:87-97 (Pubitemid 36342292)
-
(2003)
Heart Failure Reviews
, vol.8
, Issue.1
, pp. 87-97
-
-
Linke, A.1
Recchia, F.2
Zhang, X.3
Hintze, T.H.4
-
11
-
-
0035065836
-
ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis
-
DOI 10.1093/embo-reports/kve046
-
Tobiume K, Matsuzawa A, Takahashi T, Nishitoh H, Morita K, Takeda K, Minowa O, Miyazono K, Noda T, Ichijo H (2001) Ask1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis. EMBO Rep 2:222-228 (Pubitemid 32273301)
-
(2001)
EMBO Reports
, vol.2
, Issue.3
, pp. 222-228
-
-
Tobiume, K.1
Matsuzawa, A.2
Takahashi, T.3
Nishitoh, H.4
Morita, K.-I.5
Takeda, K.6
Minowa, O.7
Miyazono, K.8
Noda, T.9
Ichijo, H.10
-
12
-
-
0038338315
-
C-Myc potentiates the mitochondrial pathway of apoptosis by acting upstream of apoptosis signal-regulating kinase 1 (Ask1) in the p38 signalling cascade
-
DOI 10.1042/BJ20021565
-
Desbiens KM, Deschesnes RG, Labrie MM, Desfossés Y, Lambert H, Landry J, Bellmann K (2003) C-Myc potentiates the mitochondrial pathway of apoptosis by acting upstream of apoptosis signal-regulating kinase 1 (Ask1) in the p38 signalling cascade. Biochem J 372:631-641 (Pubitemid 36723910)
-
(2003)
Biochemical Journal
, vol.372
, Issue.2
, pp. 631-641
-
-
Desbiens, K.M.1
Deschesnes, R.G.2
Labrie, M.M.3
Desfosses, Y.4
Lambert, H.5
Landry, J.6
Bellman, K.7
-
13
-
-
0030886770
-
Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats
-
Aikawa R, Komuro I, Yamazaki T, Zou Y, Kudoh S, Tanaka M, Shiojima I, Hiroi Y, Yazaki Y (1997) Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats. J Clin Invest 100:1813-1821 (Pubitemid 27431340)
-
(1997)
Journal of Clinical Investigation
, vol.100
, Issue.7
, pp. 1813-1821
-
-
Aikawa, R.1
Komuro, I.2
Yamazaki, T.3
Zou, Y.4
Kudoh, S.5
Tanaka, M.6
Shiojima, I.7
Hiroi, Y.8
Yazaki, Y.9
-
14
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
16
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
17
-
-
0035818512
-
Differential regulation of mitogen-activated protein kinases in the failing human heart in response to mechanical unloading
-
Flesch M, Margulies KB, Mochmann HC, Engel D, Sivasubramanian N, Mann DL (2001) Differential regulation of mitogenactivated protein kinases in the failing human heart in response to mechanical unloading. Circulation 104:2273-2276 (Pubitemid 33049507)
-
(2001)
Circulation
, vol.104
, Issue.19
, pp. 2273-2276
-
-
Flesch, M.1
Margulies, K.B.2
Mochmann, H.-C.3
Engel, D.4
Sivasubramanian, N.5
Mann, D.L.6
-
18
-
-
0033120590
-
Differential expression and activation of p38 mitogen-activated protein kinase α, β, γ, and δ in inflammatory cell lineages
-
Hale KK, Trollinger D, Rihanek M, Manthey CL (1999) Differential expression and activation of p38 mitogen-activated protein kinase alpha, beta, gamma, and delta in inflammatory cell lineages. J Immunol 162:4246-4252 (Pubitemid 29314814)
-
(1999)
Journal of Immunology
, vol.162
, Issue.7
, pp. 4246-4252
-
-
Hale, K.K.1
Trollinger, D.2
Rihanek, M.3
Manthey, C.L.4
-
19
-
-
0035066383
-
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
-
Kyriakis JM, Avruch J (2001) Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 81:807-869 (Pubitemid 32267078)
-
(2001)
Physiological Reviews
, vol.81
, Issue.2
, pp. 807-869
-
-
Kyriakis, J.M.1
Avruch, J.2
-
20
-
-
0038757610
-
Mitogen-activated protein kinase: A new therapeutic target in cardiac pathology
-
DOI 10.1023/A:1024119224033
-
Ravingerová T, Barančík M, Strnisková M (2003) Mitogenactivated protein kinases: a new therapeutic target in cardiac pathology. Mol Cell Biochem 247:127-138 (Pubitemid 36798517)
-
(2003)
Molecular and Cellular Biochemistry
, vol.247
, Issue.1-2
, pp. 127-138
-
-
Ravingerova, T.1
Barancik, M.2
Strniskova, M.3
-
21
-
-
16244406892
-
Role of p38α MAPK in cardiac apoptosis and remodeling after myocardial infarction
-
DOI 10.1016/j.yjmcc.2005.01.012
-
Ren J, Zhang S, Kovacs A, Wang Y, Muslin AJ (2005) Role of p38alpha MAPK in cardiac apoptosis and remodeling after myocardial infarction. J Mol Cell Cardiol 38:617-623 (Pubitemid 40461825)
-
(2005)
Journal of Molecular and Cellular Cardiology
, vol.38
, Issue.4
, pp. 617-623
-
-
Ren, J.1
Zhang, S.2
Kovacs, A.3
Wang, Y.4
Muslin, A.J.5
-
22
-
-
0034840877
-
Activation of mitogenactivated protein kinases in the non-ischemic myocardium of an acute myocardial infarction in rats
-
Yoshida K, Yoshiyama M, Omura T, Nakamura Y, Kim S, Takeuchi K, Iwao H, Yoshikawa J (2001) Activation of mitogenactivated protein kinases in the non-ischemic myocardium of an acute myocardial infarction in rats. Jpn Circ J 65:808-814
-
(2001)
Jpn Circ J
, vol.65
, pp. 808-814
-
-
Yoshida, K.1
Yoshiyama, M.2
Omura, T.3
Nakamura, Y.4
Kim, S.5
Takeuchi, K.6
Iwao, H.7
Yoshikawa, J.8
-
23
-
-
0032572534
-
Stimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine: A role in cardiac myocyte hypertrophy?
-
DOI 10.1083/jcb.142.2.523
-
Clerk A, Michael A, Sugden PH (1998) Stimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine: a role in cardiac myocyte hypertrophy? J Cell Biol 142:523-535 (Pubitemid 28361557)
-
(1998)
Journal of Cell Biology
, vol.142
, Issue.2
, pp. 523-535
-
-
Clerk, A.1
Michael, A.2
Sugden, P.H.3
-
24
-
-
0031844392
-
Opposing effects of Jun kinase and p38 mitogen-activated protein kinases on cardiomyocyte hypertrophy
-
Nemoto S, Sheng Z, Lin A (1998) Opposing effects of Jun kinase and p38 mitogen-activated protein kinases on cardiomyocyte hypertrophy. Mol Cell Biol 18:3518-3526 (Pubitemid 28240524)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.6
, pp. 3518-3526
-
-
Nemoto, S.1
Sheng, Z.2
Lin, A.3
-
25
-
-
0031939753
-
Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family
-
DOI 10.1074/jbc.273.4.2161
-
Wang Y, Huang S, Sah VP, Ross J Jr, Brown JH, Han J, Chien KR (1998) Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family. J Biol Chem 273:2161-2168 (Pubitemid 28069266)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.4
, pp. 2161-2168
-
-
Wang, Y.1
Huang, S.2
Sah, V.P.3
Ross Jr., J.4
Brown, J.H.5
Han, J.6
Chien, K.R.7
-
26
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
Lee JC, Laydon JT, McDonnell PC, Gallagher TF, Kumar S, Green D, McNulty D, Blumenthal MJ, Keys JR, Landvatter SW, Strickler JE, McLaughlin MM, Siemens IR, Fisher SM, Livi GP, White JR, Adams JL, Young PR (1994) A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 372:739-746
-
(1994)
Nature
, vol.372
, pp. 739-746
-
-
Lee, J.C.1
Laydon, J.T.2
McDonnell, P.C.3
Gallagher, T.F.4
Kumar, S.5
Green, D.6
McNulty, D.7
Blumenthal, M.J.8
Keys, J.R.9
Landvatter, S.W.10
Strickler, J.E.11
McLaughlin, M.M.12
Siemens, I.R.13
Fisher, S.M.14
Livi, G.P.15
White, J.R.16
Adams, J.L.17
Young, P.R.18
-
27
-
-
0029982565
-
Characterization of the structure and function of a new mitogen- activated protein kinase (p38β)
-
DOI 10.1074/jbc.271.30.17920
-
Jiang Y, Chen C, Li Z, Guo W, Gegner JA, Lin S, Han J (1996) Characterization of the structure and function of a new mitogenactivated protein kinase (p38beta). J Biol Chem 271:17920-17926 (Pubitemid 26250772)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.30
, pp. 17920-17926
-
-
Jiang, Y.1
Chen, C.2
Li, Z.3
Guo, W.4
Gegner, J.A.5
Lin, S.6
Han, J.7
-
28
-
-
0030805915
-
P38-2, a novel mitogen-activated protein kinase with distinct properties
-
DOI 10.1074/jbc.272.31.19509
-
Stein B, Yang MX, Young DB, Janknecht R, Hunter T, Murray BW, Barbosa MS (1997) P38-2, a novel mitogen-activated protein kinase with distinct properties. J Biol Chem 272:19509-19517 (Pubitemid 27337751)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.31
, pp. 19509-19517
-
-
Stein, B.1
Yang, M.X.2
Young, D.B.3
Janknecht, R.4
Hunter, T.5
Murray, B.W.6
Barbosa, M.S.7
-
29
-
-
0029911710
-
ERK6, a mitogen-activated protein kinase involved in C2C12 myoblast differentiation
-
DOI 10.1073/pnas.93.9.4355
-
Lechner C, Zahalka MA, Giot JF, Møller NP, Ullrich A (1996) ERK6, a mitogen-activated protein kinase involved in C2C12 myoblast differentiation. Proc Natl Acad Sci USA 93:4355-4359 (Pubitemid 26144291)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.9
, pp. 4355-4359
-
-
Lechner, C.1
Zahalka, M.A.2
Giot, J.-F.3
Moller, N.P.H.4
Ullrich, A.5
-
30
-
-
0030581626
-
The primary structure of p38γ: A new member of p38 group of MAP kinases
-
DOI 10.1006/bbrc.1996.1662
-
Li Z, Jiang Y, Ulevitch RJ, Han J (1996) The primary structure of p38 gamma: a new member of p38 group of map kinases. Biochem Biophys Res Commun 228:334-340 (Pubitemid 26396075)
-
(1996)
Biochemical and Biophysical Research Communications
, vol.228
, Issue.2
, pp. 334-340
-
-
Li, Z.1
Jiang, Y.2
Ulevitch, R.J.3
Han, J.4
-
31
-
-
0030756286
-
Molecular cloning and characterization of a novel p38 mitogen-activated protein kinase
-
DOI 10.1074/jbc.272.38.23668
-
Wang XS, Diener K, Manthey CL, Wang S, Rosenzweig B, Bray J, Delaney J, Cole CN, Chan-Hui PY, Mantlo N, Lichenstein HS, Zukowski M, Yao Z (1997) Molecular cloning and characterization of a novel p38 mitogen-activated protein kinase. J Biol Chem 272:23668-23674 (Pubitemid 27410940)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.38
, pp. 23668-23674
-
-
Wang, X.S.1
Diener, K.2
Manthey, C.L.3
Wang, S.-W.4
Rosenzweig, B.5
Bray, J.6
Delaney, J.7
Cole, C.N.8
Chan-Hui, P.-Y.9
Mantlo, N.10
Lichenstein, H.S.11
Zukowski, M.12
Yao, Z.13
-
32
-
-
0030828701
-
Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38δ
-
DOI 10.1074/jbc.272.48.30122
-
Jiang Y, Gram H, Zhao M, New L, Gu J, Feng L, Di Padova F, Ulevitch RJ, Han J (1997) Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38 delta. J Biol Chem 272:30122-30128 (Pubitemid 27512210)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.48
, pp. 30122-30128
-
-
Jiang, Y.1
Gram, H.2
Zhao, M.3
New, L.4
Gu, J.5
Feng, L.6
Di Padova, F.7
Ulevitch, R.J.8
Han, J.9
-
33
-
-
0030755466
-
Tissue-specific pattern of stress kinase activation in ischemic/reperfused heart and kidney
-
DOI 10.1074/jbc.272.32.19943
-
Yin T, Sandhu G, Wolfgang CD, Burrier A, Webb RL, Rigel DF, Hai T, Whelan J (1997) Tissue-specific pattern of stress kinase activation in ischemic/reperfused heart and kidney. J Biol Chem 272:19943-19950 (Pubitemid 27340095)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.32
, pp. 19943-19950
-
-
Yin, T.1
Sandhu, G.2
Wolfgang, C.D.3
Burrier, A.4
Webb, R.L.5
Rigel, D.F.6
Hai, T.7
Whelan, J.8
-
34
-
-
33646758917
-
Pretreatment with adult progenitor cells improves recovery and decreases native myocardial proinflammatory signaling after ischemia
-
Wang M, Tsai BM, Crisostomo PR, Meldrum DR (2006) Pretreatment with adult progenitor cells improves recovery and decreases native myocardial proinflammatory signaling after ischemia. Shock 25:454-459
-
(2006)
Shock
, vol.25
, pp. 454-459
-
-
Wang, M.1
Tsai, B.M.2
Crisostomo, P.R.3
Meldrum, D.R.4
-
35
-
-
2442575047
-
Targeted Activation of c-Jun N-terminal Kinase in Vivo Induces Restrictive Cardiomyopathy and Conduction Defects
-
DOI 10.1074/jbc.M314142200
-
Petrich BG, Eloff BC, Lerner DL, Kovacs A, Saffitz JE, Rosenbaum DS, Wang Y (2004) Targeted activation of c-Jun N-terminal kinase in vivo induces restrictive cardiomyopathy and conduction defects. J Biol Chem 279:15330-15338 (Pubitemid 38618931)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.15
, pp. 15330-15338
-
-
Petrich, B.G.1
Eloff, B.C.2
Lerner, D.L.3
Kovacs, A.4
Saffitz, J.E.5
Rosenbaum, D.S.6
Wang, Y.7
-
36
-
-
0036074371
-
The MEKK1-JNK pathway plays a protective role in pressure overload but does not mediate cardiac hypertrophy
-
DOI 10.1172/JCI200214938
-
Sadoshima J, Montagne O, Wang Q, Yang G, Warden J, Liu J, Takagi G, Karoor V, Hong C, Johnson GL, Vatner DE, Vatner SF (2002) The MEKK1-JNK pathway plays a protective role in pressure overload but does not mediate cardiac hypertrophy. J Clin Invest 110:271-279 (Pubitemid 34787364)
-
(2002)
Journal of Clinical Investigation
, vol.110
, Issue.2
, pp. 271-279
-
-
Sadoshima, J.1
Montagne, O.2
Wang, Q.3
Yang, G.4
Warden, J.5
Liu, J.6
Takagi, G.7
Karoor, V.8
Hong, C.9
Johnson, G.L.10
Vatner, D.E.11
Vatner, S.F.12
-
37
-
-
0030762936
-
Cell stress-induced phosphorylation of ATF2 and c-Jun transcription factors in rat ventricular myocytes
-
Clerk A, Sugden PH (1997) Cell stress-induced phosphorylation of ATF2 and c-Jun transcription factors in rat ventricular myocytes. Biochem J 325:801-810 (Pubitemid 27367773)
-
(1997)
Biochemical Journal
, vol.325
, Issue.3
, pp. 801-810
-
-
Clerk, A.1
Sugden, P.H.2
|