-
1
-
-
65349083187
-
Negative regulators of T-cell activation: potential targets for therapeutic intervention in cancer, autoimmune disease, and persistent infections
-
Pentcheva-Hoang T, Corse E, Allison JP, (2009) Negative regulators of T-cell activation: potential targets for therapeutic intervention in cancer, autoimmune disease, and persistent infections. Immunol Rev 229: 67-87.
-
(2009)
Immunol Rev
, vol.229
, pp. 67-87
-
-
Pentcheva-Hoang, T.1
Corse, E.2
Allison, J.P.3
-
3
-
-
34548431024
-
A logical model provides insights into T cell receptor signaling
-
Saez-Rodriguez J, Simeoni L, Lindquist JA, Hemenway R, Bommhardt U, et al. (2007) A logical model provides insights into T cell receptor signaling. PLoS Comput Biol 3: e163.
-
(2007)
PLoS Comput Biol
, vol.3
-
-
Saez-Rodriguez, J.1
Simeoni, L.2
Lindquist, J.A.3
Hemenway, R.4
Bommhardt, U.5
-
4
-
-
0025736529
-
Comparison of the effects of FK-506, cyclosporin A and rapamycin on IL-2 production
-
Henderson DJ, Naya I, Bundick RV, Smith GM, Schmidt JA, (1991) Comparison of the effects of FK-506, cyclosporin A and rapamycin on IL-2 production. Immunol 73: 316-321.
-
(1991)
Immunol
, vol.73
, pp. 316-321
-
-
Henderson, D.J.1
Naya, I.2
Bundick, R.V.3
Smith, G.M.4
Schmidt, J.A.5
-
5
-
-
0033491981
-
Biology of the interleukin-2 receptor
-
Nelson BH, Willerford DM, (1998) Biology of the interleukin-2 receptor. Adv Immunol 70: 1-81.
-
(1998)
Adv Immunol
, vol.70
, pp. 1-81
-
-
Nelson, B.H.1
Willerford, D.M.2
-
6
-
-
67049134787
-
Logic Integer Programming Models for Signaling Networks
-
Haus U-U, Niermann K, Truemper K, Weismantel R, (2009) Logic Integer Programming Models for Signaling Networks. J Comp Biol 16: 725-743.
-
(2009)
J Comp Biol
, vol.16
, pp. 725-743
-
-
Haus, U.-U.1
Niermann, K.2
Truemper, K.3
Weismantel, R.4
-
8
-
-
77649242104
-
Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments
-
Busse D, de la Rosa M, Hobiger K, Thurley K, Flossdorf M, et al. (2010) Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments. Proc Natl Acad Sc USA 107: 3058-3063.
-
(2010)
Proc Natl Acad Sc USA
, vol.107
, pp. 3058-3063
-
-
Busse, D.1
de la Rosa, M.2
Hobiger, K.3
Thurley, K.4
Flossdorf, M.5
-
9
-
-
78649875958
-
Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response
-
Feinerman O, Jentsch G, Tkach KE, Coward JW, Hathorn MM, et al. (2010) Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response. Mol Syst Biol 6: 437.
-
(2010)
Mol Syst Biol
, vol.6
, pp. 437
-
-
Feinerman, O.1
Jentsch, G.2
Tkach, K.E.3
Coward, J.W.4
Hathorn, M.M.5
-
10
-
-
33744534672
-
Regulatory T cell adjustment of quorum growth thresholds and the control of local immune responses
-
Burroughs NJ, Miguel Paz Mendes de Oliveira B, Adrego Pinto A, (2006) Regulatory T cell adjustment of quorum growth thresholds and the control of local immune responses. J Theor Biol 241: 134-141.
-
(2006)
J Theor Biol
, vol.241
, pp. 134-141
-
-
Burroughs, N.J.1
Miguel Paz Mendes de Oliveira, B.2
Adrego Pinto, A.3
-
11
-
-
58149186477
-
PID: The Pathway Interaction Database
-
Schaefer CF, Anthony K, Krupa S, Buchoff J, Day M, et al. (2009) PID: The Pathway Interaction Database. Nucleic Acids Res 37: D674-9.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 674-679
-
-
Schaefer, C.F.1
Anthony, K.2
Krupa, S.3
Buchoff, J.4
Day, M.5
-
12
-
-
0027218948
-
Evidence that protein tyrosine kinase p56-Lck regulates the activity of phosphatidylinositol-3′-kinase in interleukin-2-dependent T-cells
-
Taichman R, Merida I, Torigoe T, Gaulton GN, Reed JC, (1993) Evidence that protein tyrosine kinase p56-Lck regulates the activity of phosphatidylinositol-3′-kinase in interleukin-2-dependent T-cells. J Biol Chem 268: 20031-20036.
-
(1993)
J Biol Chem
, vol.268
, pp. 20031-20036
-
-
Taichman, R.1
Merida, I.2
Torigoe, T.3
Gaulton, G.N.4
Reed, J.C.5
-
13
-
-
0034088346
-
Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of Syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activation
-
Zhou YJ, Magnuson KS, Cheng TP, Gadina M, Frucht DM, et al. (2000) Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of Syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activation. Mol Cell Biol 20: 4371-4380.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 4371-4380
-
-
Zhou, Y.J.1
Magnuson, K.S.2
Cheng, T.P.3
Gadina, M.4
Frucht, D.M.5
-
14
-
-
0027393848
-
Association of p56lck with IL-2 receptor beta chain is critical for the IL-2-induced activation of p56lck
-
Minami Y, Kono T, Yamada K, Kobayashi N, Kawahara A, et al. (1993) Association of p56lck with IL-2 receptor beta chain is critical for the IL-2-induced activation of p56lck. EMBO J 12: 759-768.
-
(1993)
EMBO J
, vol.12
, pp. 759-768
-
-
Minami, Y.1
Kono, T.2
Yamada, K.3
Kobayashi, N.4
Kawahara, A.5
-
15
-
-
0029039957
-
Interleukin-2 triggers a novel phosphatidylinositol 3-kinase-dependent MEK activation pathway
-
Karnitz LM, Burns LA, Sutor SL, Blenis J, Abraham RT, (1995) Interleukin-2 triggers a novel phosphatidylinositol 3-kinase-dependent MEK activation pathway. Mol Cell Biol 15: 3049-3057.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 3049-3057
-
-
Karnitz, L.M.1
Burns, L.A.2
Sutor, S.L.3
Blenis, J.4
Abraham, R.T.5
-
16
-
-
0023189665
-
The protein kinase C inhibitor H-7, inhibits antigen and IL-2-induced proliferation of murine T cell lines
-
Clark RB, Love JT, Sgroi D, Lingenheld EG, Sha'afi RI, (1987) The protein kinase C inhibitor H-7, inhibits antigen and IL-2-induced proliferation of murine T cell lines. Biochem Biophys Res Commun 145: 666-672.
-
(1987)
Biochem Biophys Res Commun
, vol.145
, pp. 666-672
-
-
Clark, R.B.1
Love, J.T.2
Sgroi, D.3
Lingenheld, E.G.4
Sha'afi, R.I.5
-
17
-
-
0024498312
-
Preferential enhancement by 2-mercaptoethanol of IL-2 responsiveness of T blast cells from old over young mice is associated with potentiated protein kinase C translocation
-
Fong TC, Makinodan T, (1989) Preferential enhancement by 2-mercaptoethanol of IL-2 responsiveness of T blast cells from old over young mice is associated with potentiated protein kinase C translocation. Immunol Lett 20: 149-154.
-
(1989)
Immunol Lett
, vol.20
, pp. 149-154
-
-
Fong, T.C.1
Makinodan, T.2
-
18
-
-
0029062127
-
The zeta isoform of protein kinase C controls interleukin-2-mediated proliferation in a murine T cell line: evidence for an additional role of protein kinase C epsilon and beta
-
Gómez J, Pitton C, García A, Martinez de Aragón A, Silva A, et al. (1995) The zeta isoform of protein kinase C controls interleukin-2-mediated proliferation in a murine T cell line: evidence for an additional role of protein kinase C epsilon and beta. Exp Cell Res 218: 105-113.
-
(1995)
Exp Cell Res
, vol.218
, pp. 105-113
-
-
Gómez, J.1
Pitton, C.2
García, A.3
Martinez de Aragón, A.4
Silva, A.5
-
19
-
-
0031568656
-
IL-2 signaling controls actin organization through Rho-like protein family, phosphatidylinositol 3-kinase, and protein kinase C-zeta
-
Gómez J, García A, R-Borlado L, Bonay P, Martínez-A C, et al. (1997) IL-2 signaling controls actin organization through Rho-like protein family, phosphatidylinositol 3-kinase, and protein kinase C-zeta. J Immunol 158: 1516-1522.
-
(1997)
J Immunol
, vol.158
, pp. 1516-1522
-
-
Gómez, J.1
García, A.2
R-Borlado, L.3
Bonay, P.4
Martínez-A, C.5
-
20
-
-
0024244789
-
Comparison of interleukin 2 and 12-O-tetradecanoylphorbol 13-acetate as signals for protein kinase C activation in purified human T lymphocytes
-
Mahé Y, Piau JP, Wakasugi N, Tursz T, Gacon G, et al. (1988) Comparison of interleukin 2 and 12-O-tetradecanoylphorbol 13-acetate as signals for protein kinase C activation in purified human T lymphocytes. Eur J Immunol 18: 2029-2036.
-
(1988)
Eur J Immunol
, vol.18
, pp. 2029-2036
-
-
Mahé, Y.1
Piau, J.P.2
Wakasugi, N.3
Tursz, T.4
Gacon, G.5
-
21
-
-
0024270674
-
The role of protein kinase C in T lymphocyte proliferation. Existence of protein kinase C-dependent and -independent pathways
-
Redondo JM, López-Rivas A, Vila V, Cragoe EJ, Fresno M, (1988) The role of protein kinase C in T lymphocyte proliferation. Existence of protein kinase C-dependent and-independent pathways. J Biol Chem 263: 17467-17470.
-
(1988)
J Biol Chem
, vol.263
, pp. 17467-17470
-
-
Redondo, J.M.1
López-Rivas, A.2
Vila, V.3
Cragoe, E.J.4
Fresno, M.5
-
22
-
-
0023792779
-
Protein kinase C is required for responses to T cell receptor ligands but not to interleukin-2 in T cells
-
Valge VE, Wong JG, Datlof BM, Sinskey AJ, Rao A, (1988) Protein kinase C is required for responses to T cell receptor ligands but not to interleukin-2 in T cells. Cell 55: 101-112.
-
(1988)
Cell
, vol.55
, pp. 101-112
-
-
Valge, V.E.1
Wong, J.G.2
Datlof, B.M.3
Sinskey, A.J.4
Rao, A.5
-
23
-
-
0026605651
-
Signal transduction by interleukin 2 in human T cells: activation of tyrosine and ribosomal S6 kinases and cell-cycle regulatory genes
-
Sawami H, Terada N, Franklin RA, Okawa H, Uchiyama T, et al. (1992) Signal transduction by interleukin 2 in human T cells: activation of tyrosine and ribosomal S6 kinases and cell-cycle regulatory genes. J Cell Physiol 151: 367-377.
-
(1992)
J Cell Physiol
, vol.151
, pp. 367-377
-
-
Sawami, H.1
Terada, N.2
Franklin, R.A.3
Okawa, H.4
Uchiyama, T.5
-
24
-
-
0021879854
-
Interleukin-2 stimulates association of protein kinase C with plasma membrane
-
Farrar WL, Anderson WB, (1985) Interleukin-2 stimulates association of protein kinase C with plasma membrane. Nature 315: 233-235.
-
(1985)
Nature
, vol.315
, pp. 233-235
-
-
Farrar, W.L.1
Anderson, W.B.2
-
25
-
-
0033007110
-
Signalling events mediating the activation of protein kinase C by interleukin-2 in cytotoxic T cells
-
Lu Y, Morley P, Durkin JP, (1999) Signalling events mediating the activation of protein kinase C by interleukin-2 in cytotoxic T cells. Cell Signal 11: 275-285.
-
(1999)
Cell Signal
, vol.11
, pp. 275-285
-
-
Lu, Y.1
Morley, P.2
Durkin, J.P.3
-
26
-
-
33749239636
-
Gö6976 is a potent inhibitor of the JAK 2 and FLT3 tyrosine kinases with significant activity in primary acute myeloid leukaemia cells
-
Grandage VL, Everington T, Linch DC, Khwaja A, (2006) Gö6976 is a potent inhibitor of the JAK 2 and FLT3 tyrosine kinases with significant activity in primary acute myeloid leukaemia cells. Br J Haematol 135: 303-316.
-
(2006)
Br J Haematol
, vol.135
, pp. 303-316
-
-
Grandage, V.L.1
Everington, T.2
Linch, D.C.3
Khwaja, A.4
-
27
-
-
33645924074
-
A novel PKC regulates ERK activation and degranulation of cytotoxic T lymphocytes: Plasticity in PKC regulation of ERK
-
Puente LG, He J-S, Ostergaard HL, (2006) A novel PKC regulates ERK activation and degranulation of cytotoxic T lymphocytes: Plasticity in PKC regulation of ERK. Eur J Immunol 36: 1009-1018.
-
(2006)
Eur J Immunol
, vol.36
, pp. 1009-1018
-
-
Puente, L.G.1
He, J.-S.2
Ostergaard, H.L.3
-
28
-
-
0034671815
-
Evidence for protein kinase C-dependent and -independent activation of mitogen-activated protein kinase in T cells: potential role of additional diacylglycerol binding proteins
-
Puente LG, Stone JC, Ostergaard HL, (2000) Evidence for protein kinase C-dependent and-independent activation of mitogen-activated protein kinase in T cells: potential role of additional diacylglycerol binding proteins. J Immunol 165: 6865-6871.
-
(2000)
J Immunol
, vol.165
, pp. 6865-6871
-
-
Puente, L.G.1
Stone, J.C.2
Ostergaard, H.L.3
-
29
-
-
0027978816
-
The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf
-
Cross DA, Alessi DR, Vandenheede JR, McDowell HE, Hundal HS, et al. (1994) The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf. Biochem J 303: 21-26.
-
(1994)
Biochem J
, vol.303
, pp. 21-26
-
-
Cross, D.A.1
Alessi, D.R.2
Vandenheede, J.R.3
McDowell, H.E.4
Hundal, H.S.5
-
30
-
-
0030048490
-
Interleukin-8 regulation of the Ras/Raf/mitogen-activated protein kinase pathway in human neutrophils
-
Knall C, Young S, Nick JA, Buhl AM, Worthen GS, et al. (1996) Interleukin-8 regulation of the Ras/Raf/mitogen-activated protein kinase pathway in human neutrophils. J Biol Chem 271: 2832-2838.
-
(1996)
J Biol Chem
, vol.271
, pp. 2832-2838
-
-
Knall, C.1
Young, S.2
Nick, J.A.3
Buhl, A.M.4
Worthen, G.S.5
-
31
-
-
0037631323
-
Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein
-
Corbit KC, Trakul N, Eves EM, Diaz B, Marshall M, et al. (2003) Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein. J Biol Chem 278: 13061-13068.
-
(2003)
J Biol Chem
, vol.278
, pp. 13061-13068
-
-
Corbit, K.C.1
Trakul, N.2
Eves, E.M.3
Diaz, B.4
Marshall, M.5
-
32
-
-
0027326410
-
Protein kinase C alpha activates RAF-1 by direct phosphorylation
-
Kolch W, Heidecker G, Kochs G, Hummel R, Vahidi H, et al. (1993) Protein kinase C alpha activates RAF-1 by direct phosphorylation. Nature 364: 249-252.
-
(1993)
Nature
, vol.364
, pp. 249-252
-
-
Kolch, W.1
Heidecker, G.2
Kochs, G.3
Hummel, R.4
Vahidi, H.5
-
33
-
-
0036558287
-
Leukotriene D(4) activates MAPK through a Ras-independent but PKCepsilon-dependent pathway in intestinal epithelial cells
-
Paruchuri S, Hallberg B, Juhas M, Larsson C, Sjölander A, (2002) Leukotriene D(4) activates MAPK through a Ras-independent but PKCepsilon-dependent pathway in intestinal epithelial cells. J Cell Sci 115: 1883-1893.
-
(2002)
J Cell Sci
, vol.115
, pp. 1883-1893
-
-
Paruchuri, S.1
Hallberg, B.2
Juhas, M.3
Larsson, C.4
Sjölander, A.5
-
34
-
-
16544383331
-
Distinct T cell dynamics in lymph nodes during the induction of tolerance and immunity
-
Hugues S, Fetler L, Bonifaz L, Helft J, Amblard F, et al. (2004) Distinct T cell dynamics in lymph nodes during the induction of tolerance and immunity. Nat Immunol 5: 1235-1242.
-
(2004)
Nat Immunol
, vol.5
, pp. 1235-1242
-
-
Hugues, S.1
Fetler, L.2
Bonifaz, L.3
Helft, J.4
Amblard, F.5
-
35
-
-
0345654347
-
Kinetics of the response of naive and memory CD8 T cells to antigen: similarities and differences
-
Zimmermann C, Prévost-Blondel A, Blaser C, Pircher H, (1999) Kinetics of the response of naive and memory CD8 T cells to antigen: similarities and differences. Eur J Immunol 29: 284-290.
-
(1999)
Eur J Immunol
, vol.29
, pp. 284-290
-
-
Zimmermann, C.1
Prévost-Blondel, A.2
Blaser, C.3
Pircher, H.4
-
36
-
-
2442496266
-
IL-2 secretion by CD4+ T cells in vivo is rapid, transient, and influenced by TCR-specific competition
-
Sojka DK, Bruniquel D, Schwartz RH, Singh NJ, (2004) IL-2 secretion by CD4+ T cells in vivo is rapid, transient, and influenced by TCR-specific competition. J Immunol 172: 6136-6143.
-
(2004)
J Immunol
, vol.172
, pp. 6136-6143
-
-
Sojka, D.K.1
Bruniquel, D.2
Schwartz, R.H.3
Singh, N.J.4
-
37
-
-
0037616179
-
Activation of C-terminal Src kinase (Csk) by phosphorylation at serine-364 depends on the Csk-Src homology 3 domain
-
Yaqub S, Abrahamsen H, Zimmerman B, Kholod N, Torgersen KM, et al. (2003) Activation of C-terminal Src kinase (Csk) by phosphorylation at serine-364 depends on the Csk-Src homology 3 domain. Biochem J 372: 271-278.
-
(2003)
Biochem J
, vol.372
, pp. 271-278
-
-
Yaqub, S.1
Abrahamsen, H.2
Zimmerman, B.3
Kholod, N.4
Torgersen, K.M.5
-
38
-
-
47949083433
-
T-cell receptor/CD28-mediated activation of human T lymphocytes induces expression of functional mu-opioid receptors
-
Börner C, Kraus J, Bedini A, Schraven B, Höllt V, (2008) T-cell receptor/CD28-mediated activation of human T lymphocytes induces expression of functional mu-opioid receptors. Mol Pharmacol 74: 496-504.
-
(2008)
Mol Pharmacol
, vol.74
, pp. 496-504
-
-
Börner, C.1
Kraus, J.2
Bedini, A.3
Schraven, B.4
Höllt, V.5
-
39
-
-
0035910759
-
Activation of the COOH-terminal Src kinase (Csk) by cAMP-dependent protein kinase inhibits signaling through the T cell receptor
-
Vang T, Torgersen KM, Sundvold V, Saxena M, Levy FO, et al. (2001) Activation of the COOH-terminal Src kinase (Csk) by cAMP-dependent protein kinase inhibits signaling through the T cell receptor. J Exp Med 193: 497-507.
-
(2001)
J Exp Med
, vol.193
, pp. 497-507
-
-
Vang, T.1
Torgersen, K.M.2
Sundvold, V.3
Saxena, M.4
Levy, F.O.5
-
40
-
-
0032102323
-
Diacylglycerols and phosphatidates: which molecular species are intracellular messengers?
-
Hodgkin MN, Pettitt TR, Martin A, Michell RH, Pemberton AJ, et al. (1998) Diacylglycerols and phosphatidates: which molecular species are intracellular messengers? Trends Biochem Sci 23: 200-204.
-
(1998)
Trends Biochem Sci
, vol.23
, pp. 200-204
-
-
Hodgkin, M.N.1
Pettitt, T.R.2
Martin, A.3
Michell, R.H.4
Pemberton, A.J.5
-
41
-
-
0037092038
-
Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C
-
Villalba M, Bi K, Hu J, Altman Y, Bushway P, et al. (2002) Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C. J Cell Biol 157: 253-263.
-
(2002)
J Cell Biol
, vol.157
, pp. 253-263
-
-
Villalba, M.1
Bi, K.2
Hu, J.3
Altman, Y.4
Bushway, P.5
-
42
-
-
76249117734
-
RasGRP1 regulates antigen-induced developmental programming by naive CD8 T cells
-
Priatel JJ, Chen X, Huang Y-H, Chow MT, Zenewicz LA, et al. (2010) RasGRP1 regulates antigen-induced developmental programming by naive CD8 T cells. J Immunol 184: 666-676.
-
(2010)
J Immunol
, vol.184
, pp. 666-676
-
-
Priatel, J.J.1
Chen, X.2
Huang, Y.-H.3
Chow, M.T.4
Zenewicz, L.A.5
-
43
-
-
41349111083
-
Oncogenic association of the Cbp/PAG adaptor protein with the Lyn tyrosine kinase in human B-NHL rafts
-
Tauzin S, Ding H, Khatib K, Ahmad I, Burdevet D, et al. (2008) Oncogenic association of the Cbp/PAG adaptor protein with the Lyn tyrosine kinase in human B-NHL rafts. Blood 111: 2310-2320.
-
(2008)
Blood
, vol.111
, pp. 2310-2320
-
-
Tauzin, S.1
Ding, H.2
Khatib, K.3
Ahmad, I.4
Burdevet, D.5
-
44
-
-
0028029813
-
Activation of JAK kinases and STAT proteins by interleukin-2 and interferon alpha, but not the T cell antigen receptor, in human T lymphocytes
-
Beadling C, Guschin D, Witthuhn BA, Ziemiecki A, Ihle JN, et al. (1994) Activation of JAK kinases and STAT proteins by interleukin-2 and interferon alpha, but not the T cell antigen receptor, in human T lymphocytes. EMBO J 13: 5605-5615.
-
(1994)
EMBO J
, vol.13
, pp. 5605-5615
-
-
Beadling, C.1
Guschin, D.2
Witthuhn, B.A.3
Ziemiecki, A.4
Ihle, J.N.5
-
45
-
-
0033534384
-
STAT5 interaction with the T cell receptor complex and stimulation of T cell proliferation
-
Welte T, Leitenberg D, Dittel BN, al-Ramadi BK, Xie B, et al. (1999) STAT5 interaction with the T cell receptor complex and stimulation of T cell proliferation. Science 283: 222-225.
-
(1999)
Science
, vol.283
, pp. 222-225
-
-
Welte, T.1
Leitenberg, D.2
Dittel, B.N.3
al-Ramadi, B.K.4
Xie, B.5
-
46
-
-
0033567048
-
Cutting edge: TCR stimulation by antibody and bacterial superantigen induces Stat3 activation in human T cells
-
Gerwien J, Nielsen M, Labuda T, Nissen MH, Svejgaard A, et al. (1999) Cutting edge: TCR stimulation by antibody and bacterial superantigen induces Stat3 activation in human T cells. J Immunol 163: 1742-1745.
-
(1999)
J Immunol
, vol.163
, pp. 1742-1745
-
-
Gerwien, J.1
Nielsen, M.2
Labuda, T.3
Nissen, M.H.4
Svejgaard, A.5
-
47
-
-
0033570054
-
CIS associates with the interleukin-2 receptor beta chain and inhibits interleukin-2-dependent signaling
-
Aman MJ, Migone TS, Sasaki A, Ascherman DP, Zhu M, et al. (1999) CIS associates with the interleukin-2 receptor beta chain and inhibits interleukin-2-dependent signaling. J Biol Chem 274: 30266-30272.
-
(1999)
J Biol Chem
, vol.274
, pp. 30266-30272
-
-
Aman, M.J.1
Migone, T.S.2
Sasaki, A.3
Ascherman, D.P.4
Zhu, M.5
-
48
-
-
22144431929
-
Genome-wide analysis of STAT target genes: elucidating the mechanism of STAT-mediated oncogenesis
-
Alvarez JV, Frank DA, (2004) Genome-wide analysis of STAT target genes: elucidating the mechanism of STAT-mediated oncogenesis. Cancer Biol Ther 3: 1045-1050.
-
(2004)
Cancer Biol Ther
, vol.3
, pp. 1045-1050
-
-
Alvarez, J.V.1
Frank, D.A.2
-
49
-
-
0035976905
-
Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytes
-
Sauer K, Liou J, Singh SB, Yablonski D, Weiss A, et al. (2001) Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytes. J Biol Chem 276: 45207-45216.
-
(2001)
J Biol Chem
, vol.276
, pp. 45207-45216
-
-
Sauer, K.1
Liou, J.2
Singh, S.B.3
Yablonski, D.4
Weiss, A.5
-
50
-
-
0033711185
-
HPK1 is activated by lymphocyte antigen receptors and negatively regulates AP-1
-
Liou J, Kiefer F, Dang A, Hashimoto A, Cobb MH, et al. (2000) HPK1 is activated by lymphocyte antigen receptors and negatively regulates AP-1. Immunity 12: 399-408.
-
(2000)
Immunity
, vol.12
, pp. 399-408
-
-
Liou, J.1
Kiefer, F.2
Dang, A.3
Hashimoto, A.4
Cobb, M.H.5
-
51
-
-
76949102246
-
T cell receptor-dependent regulation of lipid rafts controls naive CD8+ T cell homeostasis
-
Cho J-H, Kim H-O, Surh CD, Sprent J, (2010) T cell receptor-dependent regulation of lipid rafts controls naive CD8+ T cell homeostasis. Immunity 32: 214-226.
-
(2010)
Immunity
, vol.32
, pp. 214-226
-
-
Cho, J.-H.1
Kim, H.-O.2
Surh, C.D.3
Sprent, J.4
-
52
-
-
0037306143
-
Transmembrane adapters: attractants for cytoplasmic effectors
-
Lindquist JA, Simeoni L, Schraven B, (2003) Transmembrane adapters: attractants for cytoplasmic effectors. Immunol Rev 191: 165-182.
-
(2003)
Immunol Rev
, vol.191
, pp. 165-182
-
-
Lindquist, J.A.1
Simeoni, L.2
Schraven, B.3
-
53
-
-
45549102527
-
Dynamics of proximal signaling events after TCR/CD8-mediated induction of proliferation or apoptosis in mature CD8+ T cells
-
Wang X, Simeoni L, Lindquist JA, Saez-Rodriguez J, Ambach A, et al. (2008) Dynamics of proximal signaling events after TCR/CD8-mediated induction of proliferation or apoptosis in mature CD8+ T cells. J Immunol 180: 6703-6712.
-
(2008)
J Immunol
, vol.180
, pp. 6703-6712
-
-
Wang, X.1
Simeoni, L.2
Lindquist, J.A.3
Saez-Rodriguez, J.4
Ambach, A.5
-
54
-
-
33749038866
-
Reversal of the TCR stop signal by CTLA-4
-
Schneider H, Downey J, Smith A, Zinselmeyer BH, Rush C, et al. (2006) Reversal of the TCR stop signal by CTLA-4. Science 313: 1972-1975.
-
(2006)
Science
, vol.313
, pp. 1972-1975
-
-
Schneider, H.1
Downey, J.2
Smith, A.3
Zinselmeyer, B.H.4
Rush, C.5
-
55
-
-
78049424847
-
Diversity and plasticity of Th cell types predicted from regulatory network modelling
-
Naldi A, Carneiro J, Chaouiya C, Thieffry D, (2010) Diversity and plasticity of Th cell types predicted from regulatory network modelling. PLoS Comput Biol 6: e1000912.
-
(2010)
PLoS Comput Biol
, vol.6
-
-
Naldi, A.1
Carneiro, J.2
Chaouiya, C.3
Thieffry, D.4
-
56
-
-
70449481350
-
Transforming Boolean models to continuous models: methodology and application to T-cell receptor signaling
-
Wittmann DM, Krumsiek J, Saez-Rodriguez J, Lauffenburger DA, Klamt S, et al. (2009) Transforming Boolean models to continuous models: methodology and application to T-cell receptor signaling. BMC Syst Biol 3: 98.
-
(2009)
BMC Syst Biol
, vol.3
, pp. 98
-
-
Wittmann, D.M.1
Krumsiek, J.2
Saez-Rodriguez, J.3
Lauffenburger, D.A.4
Klamt, S.5
-
57
-
-
0037651066
-
Stochastic model of T cell proliferation: a calculus revealing IL-2 regulation of precursor frequencies, cell cycle time, and survival
-
Deenick EK, Gett AV, Hodgkin PD, (2003) Stochastic model of T cell proliferation: a calculus revealing IL-2 regulation of precursor frequencies, cell cycle time, and survival. J Immunol 170: 4963-4972.
-
(2003)
J Immunol
, vol.170
, pp. 4963-4972
-
-
Deenick, E.K.1
Gett, A.V.2
Hodgkin, P.D.3
-
58
-
-
77949495698
-
In vivo dynamical interactions between CD4 Tregs, CD8 Tregs and CD4+ CD25- cells in mice
-
Arazi A, Sharabi A, Zinger H, Mozes E, Neumann AU, (2009) In vivo dynamical interactions between CD4 Tregs, CD8 Tregs and CD4+ CD25- cells in mice. PLoS ONE 4: e8447.
-
(2009)
PLoS ONE
, vol.4
-
-
Arazi, A.1
Sharabi, A.2
Zinger, H.3
Mozes, E.4
Neumann, A.U.5
|