Separation of exenatide analogue mono-PEGylated with 40kDA polyethylene glycol by cation exchange chromatography

Journal of Chromatography A

Volumn 1218, Issue 39, 2011, Pages 6953-6960

  Cai, Yongqing ^a   Yue, Peng ^a  

^a Shanghai Huayi Bio Lab Co Ltd   (China)

Author keywords

Cation exchange chromatography; Exenatide analogue; Polyethylene glycol

Indexed keywords

CAPILLARY ISOELECTRIC FOCUSING; CATION EXCHANGE CHROMATOGRAPHY; EXENATIDE ANALOGUE; MOLECULAR SIZE; PEGYLATION; PHYSICOCHEMICAL PROPERTY; PRODUCT MIXTURE; RP-HPLC; SDS-PAGE; SEPARATION METHODS;

ELECTROPHORESIS; GLYCOLS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMERS; POLYETHYLENES; POSITIVE IONS; PROTEINS; SIZE EXCLUSION CHROMATOGRAPHY; THERMOPLASTICS;

POLYETHYLENE GLYCOLS;

EXENDIN 4; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 DERIVATIVE; HYBR 003; MACROGOL; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CAPILLARY ISOELECTRIC FOCUSING; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; GEL PERMEATION CHROMATOGRAPHY; HYDROPHOBICITY; IN VITRO STUDY; ION EXCHANGE CHROMATOGRAPHY; ISOMER; MOLECULAR SIZE; PHASE SEPARATION; PHYSICAL CHEMISTRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

AMINO ACID SEQUENCE; CATIONS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; CHROMATOGRAPHY, REVERSE-PHASE; GLUCAGON-LIKE PEPTIDE 1; HYPOGLYCEMIC AGENTS; MOLECULAR SEQUENCE DATA; PEPTIDE MAPPING; PEPTIDES; POLYETHYLENE GLYCOLS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; VENOMS;

EID: 80052326248     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2011.07.107     Document Type: Article

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