Positional isomers of monopegylated interferon α-2a: Isolation, characterization, and biological activity

Analytical Biochemistry

Volumn 247, Issue 2, 1997, Pages 434-440

  Monkarsh, Seth P ^a   Ma, Yuemei ^a   Aglione, Anthony ^a   Bailon, Pascal ^a   Ciolek, Doreen ^a   DeBarbieri, Barabara ^a   Graves, Mary C ^b   Hollfelder, Kurt ^a   Michel, Hanspeter ^a   Palleroni, Alicia ^a   Porter, Jill E ^a   Russoman, Emil ^a   Roy, Swapan ^a   Pan, Yu Ching E ^a  

^a HOFFMANN LA ROCHE INC   (United States)

^b ROCHE PRODUCTS LTD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANTIBIOTICS; BIOACTIVITY; CONJUGATED POLYMERS; GLYCOPROTEINS; MASS SPECTROMETRY; PLANTS (BOTANY); RECOMBINANT PROTEINS;

ANTI-PROLIFERATIVE ACTIVITIES; CATION EXCHANGES; INTERFERON ALPHAS; MASS SPECTROMETRIC ANALYSIS; PEPTIDE MAPPING; POSITIONAL ISOMERS; RECOMBINANT INTERFERON ALPHA; SINGLE POLYMER MOLECULES;

ISOMERS;

ALPHA2A INTERFERON; MACROGOL;

ANALYTIC METHOD; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL ISOLATION; COVALENT BOND; DEAMINATION; DRUG RECEPTOR BINDING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOGENICITY; ISOELECTRIC FOCUSING; MASS SPECTROMETRY; NONHUMAN; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN ANALYSIS; STRUCTURE ANALYSIS;

EID: 0031149095     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1006/abio.1997.2128     Document Type: Article

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