Activation of hiv transcription by the viral tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1)

PLoS Pathogens

Volumn 7, Issue 8, 2011, Pages

  Sakane, Naoki ^a,b   Kwon, Hye Sook ^a   Pagans, Sara ^a   Kaehlcke, Katrin ^a   Mizusawa, Yasuhiro ^b   Kamada, Masafumi ^b   Lassen, Kara G ^a   Chan, Jonathan ^a   Greene, Warner C ^a,c   Schnoelzer, Martina ^d   Ott, Melanie ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Pharmaceutical Frontier Research Laboratory   (Japan)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LYSINE SPECIFIC DEMETHYLASE 1; POSITIVE TRANSCRIPTION ELONGATION FACTOR B; RNA; SHORT HAIRPIN RNA; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG; VIRUS ENZYME; VIRUS RNA; HISTONE DEMETHYLASE; KDM1A PROTEIN, HUMAN; PHENELZINE;

ACETYLATION; ARTICLE; CONTROLLED STUDY; DEMETHYLATION; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOPRECIPITATION; IN VIVO STUDY; MASS SPECTROMETRY; MOLECULAR INTERACTION; MOLECULE; NONHUMAN; PROMOTER REGION; PROTEIN MODIFICATION; RNA BINDING; T LYMPHOCYTE; VIRUS ACTIVATION; VIRUS TRANSCRIPTION; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; GENETIC EPIGENESIS; GENETIC TRANSCRIPTION; IMMUNOLOGY; METABOLISM; METHYLATION; PHYSIOLOGY; RABBIT; VIRUS GENE;

ACETYLATION; ANIMALS; EPIGENESIS, GENETIC; GENES, VIRAL; HISTONE DEMETHYLASES; METHYLATION; PHENELZINE; POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B; RABBITS; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; TRANSCRIPTION, GENETIC;

EID: 80052305523     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002184     Document Type: Article

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