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Volumn 49, Issue 4, 2011, Pages 662-672

Bone vs. fat: Embryonic origin of progenitors determines response to androgen in adipocytes and osteoblasts

Author keywords

Androgen; Mesenchymal stem cell; Neural crest; Periosteum; Testosterone

Indexed keywords

ALKALINE PHOSPHATASE; ANDROGEN; ANDROGEN RECEPTOR; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 15; BONE MORPHOGENETIC PROTEIN 6; DICKKOPF 1 PROTEIN; EPHRIN B3; FIBROBLAST GROWTH FACTOR 4; HEPATOCYTE NUCLEAR FACTOR 1BETA; HERMES ANTIGEN; MESSENGER RNA; OSTEOCALCIN; SMAD2 PROTEIN; TRANSCRIPTION FACTOR PITX2; TRANSCRIPTION FACTOR SIX3; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN;

EID: 80052293939     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2011.06.010     Document Type: Article
Times cited : (18)

References (54)
  • 2
    • 79952109843 scopus 로고    scopus 로고
    • Male pubertal development: role of androgen therapy on bone mass and body composition
    • Vignozzi L., Morelli A., Filippi S., Maggi M., Forti G. Male pubertal development: role of androgen therapy on bone mass and body composition. J Endocrinol Invest 2011, 33:27-32.
    • (2011) J Endocrinol Invest , vol.33 , pp. 27-32
    • Vignozzi, L.1    Morelli, A.2    Filippi, S.3    Maggi, M.4    Forti, G.5
  • 4
    • 27744521675 scopus 로고    scopus 로고
    • Androgens and bone growth: it's location, location, location
    • Wiren K. Androgens and bone growth: it's location, location, location. Curr Opin Pharmacol 2005, 5:626-632.
    • (2005) Curr Opin Pharmacol , vol.5 , pp. 626-632
    • Wiren, K.1
  • 6
    • 78049380720 scopus 로고    scopus 로고
    • Skeletal sexual dimorphism: relative contribution of sex steroids, GH-IGF1, and mechanical loading
    • Callewaert F., Sinnesael M., Gielen E., Boonen S., Vanderschueren D. Skeletal sexual dimorphism: relative contribution of sex steroids, GH-IGF1, and mechanical loading. J Endocrinol 2010, 207:127-134.
    • (2010) J Endocrinol , vol.207 , pp. 127-134
    • Callewaert, F.1    Sinnesael, M.2    Gielen, E.3    Boonen, S.4    Vanderschueren, D.5
  • 7
    • 77953471006 scopus 로고    scopus 로고
    • Sexual dimorphism in cortical bone size and strength but not density is determined by independent and time-specific actions of sex steroids and IGF-1: evidence from pubertal mouse models
    • Callewaert F., Venken K., Kopchick J., Torcasio A., van Lenthe G., Boonen S., et al. Sexual dimorphism in cortical bone size and strength but not density is determined by independent and time-specific actions of sex steroids and IGF-1: evidence from pubertal mouse models. J Bone Miner Res 2010, 25:617-626.
    • (2010) J Bone Miner Res , vol.25 , pp. 617-626
    • Callewaert, F.1    Venken, K.2    Kopchick, J.3    Torcasio, A.4    van Lenthe, G.5    Boonen, S.6
  • 8
    • 3042541735 scopus 로고    scopus 로고
    • Targeted overexpression of androgen receptor in osteoblasts: unexpected complex bone phenotype in growing animals
    • Wiren K.M., Zhang X.W., Toombs A.R., Kasparcova V., Gentile M.A., Harada S., et al. Targeted overexpression of androgen receptor in osteoblasts: unexpected complex bone phenotype in growing animals. Endocrinology 2004, 145:3507-3522.
    • (2004) Endocrinology , vol.145 , pp. 3507-3522
    • Wiren, K.M.1    Zhang, X.W.2    Toombs, A.R.3    Kasparcova, V.4    Gentile, M.A.5    Harada, S.6
  • 9
    • 49149119954 scopus 로고    scopus 로고
    • Targeting of androgen receptor in bone reveals a lack of androgen anabolic action and inhibition of osteogenesis. A model for compartment-specific androgen action in the skeleton
    • Wiren K.M., Semirale A.A., Zhang X.W., Woo A., Tommasini S.M., Price C., et al. Targeting of androgen receptor in bone reveals a lack of androgen anabolic action and inhibition of osteogenesis. A model for compartment-specific androgen action in the skeleton. Bone 2008, 43:440-451.
    • (2008) Bone , vol.43 , pp. 440-451
    • Wiren, K.M.1    Semirale, A.A.2    Zhang, X.W.3    Woo, A.4    Tommasini, S.M.5    Price, C.6
  • 10
    • 78751684940 scopus 로고    scopus 로고
    • Long-term effects of dihydrotestosterone treatment on prostate growth in healthy, middle-aged men without prostate disease: a randomized, placebo-controlled trial
    • Idan A., Griffiths K., Harwood D., Seibel M., Turner L., Conway A., et al. Long-term effects of dihydrotestosterone treatment on prostate growth in healthy, middle-aged men without prostate disease: a randomized, placebo-controlled trial. Ann Intern Med 2010, 153:621-632.
    • (2010) Ann Intern Med , vol.153 , pp. 621-632
    • Idan, A.1    Griffiths, K.2    Harwood, D.3    Seibel, M.4    Turner, L.5    Conway, A.6
  • 11
    • 77953100242 scopus 로고    scopus 로고
    • Effects of transdermal testosterone on bone and muscle in older men with low bioavailable testosterone levels, low bone mass, and physical frailty
    • Kenny A., Kleppinger A., Annis K., Rathier M., Browner B., Judge J., et al. Effects of transdermal testosterone on bone and muscle in older men with low bioavailable testosterone levels, low bone mass, and physical frailty. J Am Geriatr Soc 2010, 58:1134-1143.
    • (2010) J Am Geriatr Soc , vol.58 , pp. 1134-1143
    • Kenny, A.1    Kleppinger, A.2    Annis, K.3    Rathier, M.4    Browner, B.5    Judge, J.6
  • 12
    • 25444504798 scopus 로고    scopus 로고
    • Effect of testosterone replacement on trabecular architecture in hypogonadal men
    • Benito M., Vasilic B., Wehrli F.W., Bunker B., Wald M., Gomberg B., et al. Effect of testosterone replacement on trabecular architecture in hypogonadal men. J Bone Miner Res 2005, 20:1785-1791.
    • (2005) J Bone Miner Res , vol.20 , pp. 1785-1791
    • Benito, M.1    Vasilic, B.2    Wehrli, F.W.3    Bunker, B.4    Wald, M.5    Gomberg, B.6
  • 13
    • 2442543161 scopus 로고    scopus 로고
    • Long-term testosterone gel (AndroGel) treatment maintains beneficial effects on sexual function and mood, lean and fat mass, and bone mineral density in hypogonadal men
    • Wang C., Cunningham G., Dobs A., Iranmanesh A., Matsumoto A., Snyder P., et al. Long-term testosterone gel (AndroGel) treatment maintains beneficial effects on sexual function and mood, lean and fat mass, and bone mineral density in hypogonadal men. J Clin Endocrinol Metab 2004, 89:2085-2098.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 2085-2098
    • Wang, C.1    Cunningham, G.2    Dobs, A.3    Iranmanesh, A.4    Matsumoto, A.5    Snyder, P.6
  • 14
    • 77649181504 scopus 로고    scopus 로고
    • Signaling pathways implicated in androgen regulation of endocortical bone
    • Wiren K., Semirale A., Hashimoto J., Zhang X. Signaling pathways implicated in androgen regulation of endocortical bone. Bone 2010, 46:710-723.
    • (2010) Bone , vol.46 , pp. 710-723
    • Wiren, K.1    Semirale, A.2    Hashimoto, J.3    Zhang, X.4
  • 15
    • 60549100308 scopus 로고    scopus 로고
    • The contribution of different cell lineages to bone repair: exploring a role for muscle stem cells
    • Schindeler A., Liu R., Little D. The contribution of different cell lineages to bone repair: exploring a role for muscle stem cells. Differentiation 2009, 77:12-18.
    • (2009) Differentiation , vol.77 , pp. 12-18
    • Schindeler, A.1    Liu, R.2    Little, D.3
  • 16
    • 53349096948 scopus 로고    scopus 로고
    • Embryonic origin and Hox status determine progenitor cell fate during adult bone regeneration
    • Leucht P., Kim J., Amasha R., James A., Girod S., Helms J. Embryonic origin and Hox status determine progenitor cell fate during adult bone regeneration. Development 2008, 135:2845-2854.
    • (2008) Development , vol.135 , pp. 2845-2854
    • Leucht, P.1    Kim, J.2    Amasha, R.3    James, A.4    Girod, S.5    Helms, J.6
  • 17
    • 0345737275 scopus 로고    scopus 로고
    • Regulation of body composition by androgens
    • Bhasin S. Regulation of body composition by androgens. J Endocrinol Invest 2003, 26:814-822.
    • (2003) J Endocrinol Invest , vol.26 , pp. 814-822
    • Bhasin, S.1
  • 18
    • 0036176556 scopus 로고    scopus 로고
    • Andropause: clinical implications of the decline in serum testosterone levels with aging in men
    • Matsumoto A. Andropause: clinical implications of the decline in serum testosterone levels with aging in men. J Gerontol A Biol Sci Med Sci 2002, 57:M76-M99.
    • (2002) J Gerontol A Biol Sci Med Sci , vol.57
    • Matsumoto, A.1
  • 19
    • 2942541820 scopus 로고    scopus 로고
    • Effects of androgenic-anabolic steroids in athletes
    • Hartgens F., Kuipers H. Effects of androgenic-anabolic steroids in athletes. Sports Med 2004, 34:513-554.
    • (2004) Sports Med , vol.34 , pp. 513-554
    • Hartgens, F.1    Kuipers, H.2
  • 20
    • 0025083282 scopus 로고
    • Visceral fat accumulation in men is positively associated with insulin, glucose, and C-peptide levels, but negatively with testosterone levels
    • Seidell J., Bjorntorp P., Sjostrom L., Kvist H., Sannerstedt R. Visceral fat accumulation in men is positively associated with insulin, glucose, and C-peptide levels, but negatively with testosterone levels. Metabolism 1990, 39:897-901.
    • (1990) Metabolism , vol.39 , pp. 897-901
    • Seidell, J.1    Bjorntorp, P.2    Sjostrom, L.3    Kvist, H.4    Sannerstedt, R.5
  • 21
    • 77949426910 scopus 로고    scopus 로고
    • The benefits and risks of testosterone replacement therapy: a review
    • Bassil N., Alkaade S., Morley J. The benefits and risks of testosterone replacement therapy: a review. Ther Clin Risk Manag 2009, 5:427-448.
    • (2009) Ther Clin Risk Manag , vol.5 , pp. 427-448
    • Bassil, N.1    Alkaade, S.2    Morley, J.3
  • 22
    • 0031733473 scopus 로고    scopus 로고
    • Testosterone deficiency in young men: marked alterations in whole body protein kinetics, strength, and adiposity
    • Mauras N., Hayes V., Welch S., Rini A., Helgeson K., Dokler M., et al. Testosterone deficiency in young men: marked alterations in whole body protein kinetics, strength, and adiposity. J Clin Endocrinol Metab 1998, 83:1886-1892.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1886-1892
    • Mauras, N.1    Hayes, V.2    Welch, S.3    Rini, A.4    Helgeson, K.5    Dokler, M.6
  • 23
    • 1442327764 scopus 로고    scopus 로고
    • Dose-dependent effects of testosterone on regional adipose tissue distribution in healthy young men
    • Woodhouse L.J., Gupta N., Bhasin M., Singh A.B., Ross R., Phillips J., et al. Dose-dependent effects of testosterone on regional adipose tissue distribution in healthy young men. J Clin Endocrinol Metab 2004, 89:718-726.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 718-726
    • Woodhouse, L.J.1    Gupta, N.2    Bhasin, M.3    Singh, A.B.4    Ross, R.5    Phillips, J.6
  • 24
    • 68749100675 scopus 로고    scopus 로고
    • Sexual dimorphism in body fat distribution and risk for cardiovascular diseases
    • Nedungadi T., Clegg D. Sexual dimorphism in body fat distribution and risk for cardiovascular diseases. J Cardiovasc Transl Res 2009, 2:321-327.
    • (2009) J Cardiovasc Transl Res , vol.2 , pp. 321-327
    • Nedungadi, T.1    Clegg, D.2
  • 25
    • 80051492645 scopus 로고    scopus 로고
    • Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation
    • Semirale A., Zhang X., Wiren K. Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation. J Cell Biochem 2011, 112:1773-1786.
    • (2011) J Cell Biochem , vol.112 , pp. 1773-1786
    • Semirale, A.1    Zhang, X.2    Wiren, K.3
  • 26
    • 41449116604 scopus 로고    scopus 로고
    • Ontogeny and multipotency of neural crest-derived stem cells in mouse bone marrow, dorsal root ganglia, and whisker pad
    • Nagoshi N., Shibata S., Kubota Y., Nakamura M., Nagai Y., Satoh E., et al. Ontogeny and multipotency of neural crest-derived stem cells in mouse bone marrow, dorsal root ganglia, and whisker pad. Cell Stem Cell 2008, 2:392-403.
    • (2008) Cell Stem Cell , vol.2 , pp. 392-403
    • Nagoshi, N.1    Shibata, S.2    Kubota, Y.3    Nakamura, M.4    Nagai, Y.5    Satoh, E.6
  • 27
    • 53349160483 scopus 로고    scopus 로고
    • Developmental origin of adipocytes: new insights into a pending question
    • Billon N., Monteiro M., Dani C. Developmental origin of adipocytes: new insights into a pending question. Biol Cell 2008, 100:563-575.
    • (2008) Biol Cell , vol.100 , pp. 563-575
    • Billon, N.1    Monteiro, M.2    Dani, C.3
  • 28
    • 0346655258 scopus 로고    scopus 로고
    • Comparison of RiboGreen and 18S rRNA quantitation for normalizing real-time RT-PCR expression analysis
    • Hashimoto J.G., Beadles-Bohling A.S., Wiren K.M. Comparison of RiboGreen and 18S rRNA quantitation for normalizing real-time RT-PCR expression analysis. Biotechniques 2004, 36(54-6):58-60.
    • (2004) Biotechniques , vol.36 , Issue.54 , pp. 58-60
    • Hashimoto, J.G.1    Beadles-Bohling, A.S.2    Wiren, K.M.3
  • 29
    • 43049111765 scopus 로고    scopus 로고
    • Review of fate-mapping studies of osteogenic cranial neural crest in vertebrates
    • Gross J., Hanken J. Review of fate-mapping studies of osteogenic cranial neural crest in vertebrates. Dev Biol 2008, 317:389-400.
    • (2008) Dev Biol , vol.317 , pp. 389-400
    • Gross, J.1    Hanken, J.2
  • 30
    • 77955606279 scopus 로고    scopus 로고
    • A subset of osteoblasts expressing high endogenous levels of PPARgamma switches fate to adipocytes in the rat calvaria cell culture model
    • Yoshiko Y., Oizumi K., Hasegawa T., Minamizaki T., Tanne K., Maeda N., et al. A subset of osteoblasts expressing high endogenous levels of PPARgamma switches fate to adipocytes in the rat calvaria cell culture model. PLoS One 2010, 5:e11782.
    • (2010) PLoS One , vol.5
    • Yoshiko, Y.1    Oizumi, K.2    Hasegawa, T.3    Minamizaki, T.4    Tanne, K.5    Maeda, N.6
  • 32
    • 8444238558 scopus 로고    scopus 로고
    • Periosteum: biology, regulation, and response to osteoporosis therapies
    • Allen M., Hock J., Burr D. Periosteum: biology, regulation, and response to osteoporosis therapies. Bone 2004, 35:1003-1012.
    • (2004) Bone , vol.35 , pp. 1003-1012
    • Allen, M.1    Hock, J.2    Burr, D.3
  • 33
    • 0037778765 scopus 로고    scopus 로고
    • Periosteal bone formation-a neglected determinant of bone strength
    • Seeman E. Periosteal bone formation-a neglected determinant of bone strength. N Engl J Med 2003, 349:320-323.
    • (2003) N Engl J Med , vol.349 , pp. 320-323
    • Seeman, E.1
  • 34
    • 37349043960 scopus 로고    scopus 로고
    • Structural and cellular differences between metaphyseal and diaphyseal periosteum in different aged rats
    • Fan W., Crawford R., Xiao Y. Structural and cellular differences between metaphyseal and diaphyseal periosteum in different aged rats. Bone 2008, 42:81-89.
    • (2008) Bone , vol.42 , pp. 81-89
    • Fan, W.1    Crawford, R.2    Xiao, Y.3
  • 35
    • 79954449018 scopus 로고    scopus 로고
    • Net change in periosteal strain during stance shift loading after surgery correlates to rapid de novo bone generation in critically sized defects
    • McBride S., Dolejs S., Brianza S., Knothe U., Knothe Tate M. Net change in periosteal strain during stance shift loading after surgery correlates to rapid de novo bone generation in critically sized defects. Ann Biomed Eng 2011, 39:1570-1581.
    • (2011) Ann Biomed Eng , vol.39 , pp. 1570-1581
    • McBride, S.1    Dolejs, S.2    Brianza, S.3    Knothe, U.4    Knothe Tate, M.5
  • 36
    • 77953383151 scopus 로고    scopus 로고
    • Androgen receptor disruption increases the osteogenic response to mechanical loading in male mice
    • Callewaert F., Bakker A., Schrooten J., Van Meerbeek B., Verhoeven G., Boonen S., et al. Androgen receptor disruption increases the osteogenic response to mechanical loading in male mice. J Bone Miner Res 2010, 25:124-131.
    • (2010) J Bone Miner Res , vol.25 , pp. 124-131
    • Callewaert, F.1    Bakker, A.2    Schrooten, J.3    Van Meerbeek, B.4    Verhoeven, G.5    Boonen, S.6
  • 37
    • 34247495109 scopus 로고    scopus 로고
    • Mechanosensation and transduction in osteocytes
    • Bonewald L. Mechanosensation and transduction in osteocytes. Bonekey Osteovision 2006, 3:7-15.
    • (2006) Bonekey Osteovision , vol.3 , pp. 7-15
    • Bonewald, L.1
  • 38
    • 67349109815 scopus 로고    scopus 로고
    • The role of osteocytes in bone mechanotransduction
    • Santos A., Bakker A., Klein-Nulend J. The role of osteocytes in bone mechanotransduction. Osteoporos Int 2009, 20:1027-1031.
    • (2009) Osteoporos Int , vol.20 , pp. 1027-1031
    • Santos, A.1    Bakker, A.2    Klein-Nulend, J.3
  • 39
    • 33646084390 scopus 로고    scopus 로고
    • Osteoblast and osteocyte apoptosis associated with androgen action in bone: requirement of increased Bax/Bcl-2 ratio
    • Wiren K.M., Toombs A.R., Semirale A.A., Zhang X. Osteoblast and osteocyte apoptosis associated with androgen action in bone: requirement of increased Bax/Bcl-2 ratio. Bone 2006, 38:637-651.
    • (2006) Bone , vol.38 , pp. 637-651
    • Wiren, K.M.1    Toombs, A.R.2    Semirale, A.A.3    Zhang, X.4
  • 40
    • 0018651824 scopus 로고
    • In vitro studies on skeletogenic potential of membrane bone periosteal cells
    • Thorogood P. In vitro studies on skeletogenic potential of membrane bone periosteal cells. J Embryol Exp Morphol 1979, 54:185-207.
    • (1979) J Embryol Exp Morphol , vol.54 , pp. 185-207
    • Thorogood, P.1
  • 41
    • 0021793932 scopus 로고
    • Induction of deer antlers by transplanted periosteum. I. Graft size and shape
    • Goss R., Powel R. Induction of deer antlers by transplanted periosteum. I. Graft size and shape. J Exp Zool 1985, 235:359-373.
    • (1985) J Exp Zool , vol.235 , pp. 359-373
    • Goss, R.1    Powel, R.2
  • 42
    • 33947163465 scopus 로고    scopus 로고
    • Identification of key tissue type for antler regeneration through pedicle periosteum deletion
    • Li C., Mackintosh C., Martin S., Clark D. Identification of key tissue type for antler regeneration through pedicle periosteum deletion. Cell Tissue Res 2007, 328:65-75.
    • (2007) Cell Tissue Res , vol.328 , pp. 65-75
    • Li, C.1    Mackintosh, C.2    Martin, S.3    Clark, D.4
  • 43
    • 0037335275 scopus 로고    scopus 로고
    • Effects of testosterone on pedicle formation and its transformation to antler in castrated male, freemartin and normal female red deer (Cervus elaphus)
    • Li C., Littlejohn R., Corson I., Suttie J. Effects of testosterone on pedicle formation and its transformation to antler in castrated male, freemartin and normal female red deer (Cervus elaphus). Gen Comp Endocrinol 2003, 131:21-31.
    • (2003) Gen Comp Endocrinol , vol.131 , pp. 21-31
    • Li, C.1    Littlejohn, R.2    Corson, I.3    Suttie, J.4
  • 44
    • 61749092077 scopus 로고    scopus 로고
    • Testosterone, but not IGF-1, LH, prolactin or cortisol, may serve as antler-stimulating hormone in red deer stags (Cervus elaphus)
    • Bartos L., Schams D., Bubenik G. Testosterone, but not IGF-1, LH, prolactin or cortisol, may serve as antler-stimulating hormone in red deer stags (Cervus elaphus). Bone 2009, 44:691-698.
    • (2009) Bone , vol.44 , pp. 691-698
    • Bartos, L.1    Schams, D.2    Bubenik, G.3
  • 45
    • 79953150956 scopus 로고    scopus 로고
    • Effect of different factors on proliferation of antler cells, cultured in vitro
    • Kuzmova E., Bartos L., Kotrba R., Bubenik G. Effect of different factors on proliferation of antler cells, cultured in vitro. PLoS One 2011, 6:e18053.
    • (2011) PLoS One , vol.6
    • Kuzmova, E.1    Bartos, L.2    Kotrba, R.3    Bubenik, G.4
  • 46
    • 68649119298 scopus 로고    scopus 로고
    • Differential FGF ligands and FGF receptors expression pattern in frontal and parietal calvarial bones
    • Quarto N., Behr B., Li S., Longaker M. Differential FGF ligands and FGF receptors expression pattern in frontal and parietal calvarial bones. Cells Tissues Organs 2009, 190:158-169.
    • (2009) Cells Tissues Organs , vol.190 , pp. 158-169
    • Quarto, N.1    Behr, B.2    Li, S.3    Longaker, M.4
  • 47
    • 77954699773 scopus 로고    scopus 로고
    • Origin matters: differences in embryonic tissue origin and Wnt signaling determine the osteogenic potential and healing capacity of frontal and parietal calvarial bones
    • Quarto N., Wan D., Kwan M., Panetta N., Li S., Longaker M. Origin matters: differences in embryonic tissue origin and Wnt signaling determine the osteogenic potential and healing capacity of frontal and parietal calvarial bones. J Bone Miner Res 2010, 25:1680-1694.
    • (2010) J Bone Miner Res , vol.25 , pp. 1680-1694
    • Quarto, N.1    Wan, D.2    Kwan, M.3    Panetta, N.4    Li, S.5    Longaker, M.6
  • 48
    • 34548536383 scopus 로고    scopus 로고
    • Bone voyage: an expedition into the molecular and cellular parameters affecting bone graft fate
    • Helms J., Amasha R., Leucht P. Bone voyage: an expedition into the molecular and cellular parameters affecting bone graft fate. Bone 2007, 41:479-485.
    • (2007) Bone , vol.41 , pp. 479-485
    • Helms, J.1    Amasha, R.2    Leucht, P.3
  • 50
    • 79551525437 scopus 로고    scopus 로고
    • Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells
    • Garza L., Yang C., Zhao T., Blatt H., Lee M., He H., et al. Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells. J Clin Invest 2011, 121:613-622.
    • (2011) J Clin Invest , vol.121 , pp. 613-622
    • Garza, L.1    Yang, C.2    Zhao, T.3    Blatt, H.4    Lee, M.5    He, H.6
  • 51
    • 77951051774 scopus 로고    scopus 로고
    • Stem cells with neural crest characteristics derived from the bulge region of cultured human hair follicles
    • Yu H., Kumar S., Kossenkov A., Showe L., Xu X. Stem cells with neural crest characteristics derived from the bulge region of cultured human hair follicles. J Invest Dermatol 2010, 130:1227-1236.
    • (2010) J Invest Dermatol , vol.130 , pp. 1227-1236
    • Yu, H.1    Kumar, S.2    Kossenkov, A.3    Showe, L.4    Xu, X.5
  • 52
    • 13844275666 scopus 로고    scopus 로고
    • A novel surgical procedure for bridging of massive bone defects
    • Knothe U., Springfield D. A novel surgical procedure for bridging of massive bone defects. World J Surg Oncol 2005, 3:7.
    • (2005) World J Surg Oncol , vol.3 , pp. 7
    • Knothe, U.1    Springfield, D.2
  • 53
    • 18844419177 scopus 로고    scopus 로고
    • Free vascularized corticoperiosteal bone graft for the treatment of persistent nonunion of the clavicle
    • Fuchs B., Steinmann S., Bishop A. Free vascularized corticoperiosteal bone graft for the treatment of persistent nonunion of the clavicle. J Shoulder Elbow Surg 2005, 14:264-268.
    • (2005) J Shoulder Elbow Surg , vol.14 , pp. 264-268
    • Fuchs, B.1    Steinmann, S.2    Bishop, A.3
  • 54
    • 77952966866 scopus 로고    scopus 로고
    • RBMP represses Wnt signaling and influences skeletal progenitor cell fate specification during bone repair
    • Minear S., Leucht P., Miller S., Helms J. rBMP represses Wnt signaling and influences skeletal progenitor cell fate specification during bone repair. J Bone Miner Res 2010, 25:1196-1207.
    • (2010) J Bone Miner Res , vol.25 , pp. 1196-1207
    • Minear, S.1    Leucht, P.2    Miller, S.3    Helms, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.