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Volumn 153, Issue 10, 2010, Pages 621-632

Long-term effects of dihydrotestosterone treatment on prostate growth in healthy, middle-aged men without prostate disease: A randomized, placebo-controlled trial

Author keywords

[No Author keywords available]

Indexed keywords

3BETA ANDROSTANEDIOL; ANDROGEN; ANDROSTANEDIOL; ANDROSTANOLONE; CREATININE; ESTRADIOL; FOLLITROPIN; HEMOGLOBIN; LUTEINIZING HORMONE; PLACEBO; PROCOLLAGEN C PROTEINASE; PROSTATE SPECIFIC ANTIGEN;

EID: 78751684940     PISSN: 00034819     EISSN: 15393704     Source Type: Journal    
DOI: 10.7326/0003-4819-153-10-201011160-00004     Document Type: Article
Times cited : (80)

References (62)
  • 1
    • 0021149603 scopus 로고
    • The development of human benign prostatic hyperplasia with age
    • PMID: 6206240
    • Berry SJ, Coffey DS, Walsh PC, Ewing LL. The development of human benign prostatic hyperplasia with age. J Urol. 1984;132:474-9. [PMID: 6206240]
    • (1984) J Urol , vol.132 , pp. 474-479
    • Berry, S.J.1    Coffey, D.S.2    Walsh, P.C.3    Ewing, L.L.4
  • 2
    • 0029684668 scopus 로고    scopus 로고
    • Benign prostatic hyperplasia: A review of its histogenesis and natural history
    • PMID: 8630233
    • Oesterling JE. Benign prostatic hyperplasia: a review of its histogenesis and natural history. Prostate Suppl. 1996;6:67-73. [PMID: 8630233]
    • (1996) Prostate Suppl , vol.6 , pp. 67-73
    • Oesterling, J.E.1
  • 3
    • 33645728233 scopus 로고    scopus 로고
    • An evaluation of the economic costs and patient-related consequences of treatments for benign prostatic hyperplasia
    • PMID: 16542339
    • DiSantostefano RL, Biddle AK, Lavelle JP. An evaluation of the economic costs and patient-related consequences of treatments for benign prostatic hyperplasia. BJU Int. 2006;97:1007-16. [PMID: 16542339]
    • (2006) BJU Int , vol.97 , pp. 1007-1016
    • DiSantostefano, R.L.1    Biddle, A.K.2    Lavelle, J.P.3
  • 4
    • 72949093736 scopus 로고    scopus 로고
    • Tamsulosin versus terazosin for benign prostatic hyperplasia: A systematic review
    • PMID: 19886768
    • Dong Z, Wang Z, Yang K, Liu Y, Gao W, Chen W. Tamsulosin versus terazosin for benign prostatic hyperplasia: a systematic review. Syst Biol Reprod Med. 2009;55:129-36. [PMID: 19886768]
    • (2009) Syst Biol Reprod Med , vol.55 , pp. 129-136
    • Dong, Z.1    Wang, Z.2    Yang, K.3    Liu, Y.4    Gao, W.5    Chen, W.6
  • 5
    • 0347882750 scopus 로고    scopus 로고
    • The long-term effect of doxazosin, finasteride, and combination therapy on the clinical progression of benign prostatic hyperplasia
    • Medical Therapy of Prostatic Symptoms (MTOPS) Research Group. PMID: 14681504
    • McConnell JD, Roehrborn CG, Bautista OM, Andriole GL Jr, Dixon CM, Kusek JW, et al; Medical Therapy of Prostatic Symptoms (MTOPS) Research Group. The long-term effect of doxazosin, finasteride, and combination therapy on the clinical progression of benign prostatic hyperplasia. N Engl J Med. 2003; 349:2387-98. [PMID: 14681504]
    • (2003) N Engl J Med , vol.349 , pp. 2387-2398
    • McConnell, J.D.1    Roehrborn, C.G.2    Bautista, O.M.3    Andriole Jr., G.L.4    Dixon, C.M.5    Kusek, J.W.6
  • 6
    • 52749099638 scopus 로고    scopus 로고
    • Progression of benign prostatic hyperplasia: Systematic review of the placebo arms of clinical trials
    • PMID: 18549433
    • Emberton M, Fitzpatrick JM, Garcia-Losa M, Qizilbash N, Djavan B. Progression of benign prostatic hyperplasia: systematic review of the placebo arms of clinical trials. BJU Int. 2008;102:981-6. [PMID: 18549433]
    • (2008) BJU Int , vol.102 , pp. 981-986
    • Emberton, M.1    Fitzpatrick, J.M.2    Garcia-Losa, M.3    Qizilbash, N.4    Djavan, B.5
  • 8
    • 33644824294 scopus 로고    scopus 로고
    • The natural history of benign prostatic hyperplasia
    • discussion 21-2. [PMID: 16507045]
    • Fitzpatrick JM. The natural history of benign prostatic hyperplasia. BJU Int. 2006;97 Suppl 2:3-6; discussion 21-2. [PMID: 16507045]
    • (2006) BJU Int , vol.97 , Issue.SUPPL. 2 , pp. 3-6
    • Fitzpatrick, J.M.1
  • 9
    • 33846413629 scopus 로고    scopus 로고
    • Essential role for estrogen receptor beta in stromal-epithelial regulation of prostatic hyperplasia
    • DOI 10.1210/en.2006-0906
    • McPherson SJ, Ellem SJ, Simpson ER, Patchev V, Fritzemeier KH, Risbridger GP. Essential role for estrogen receptor beta in stromal-epithelial regulation of prostatic hyperplasia. Endocrinology. 2007;148:566-74. [PMID: 17068134] (Pubitemid 46143161)
    • (2007) Endocrinology , vol.148 , Issue.2 , pp. 566-574
    • McPherson, S.J.1    Ellem, S.J.2    Simpson, E.R.3    Patchev, V.4    Fritzemeier, K.-H.5    Risbridger, G.P.6
  • 11
    • 0032454317 scopus 로고    scopus 로고
    • Dihydrotestosterone: A rationale for its use as a non-aromatizable androgen replacement therapeutic agent
    • Swerdloff RS, Wang C. Dihydrotestosterone: a rationale for its use as a non-aromatizable androgen replacement therapeutic agent. Baillieres Clin Endocrinol Metab. 1998;12:501-6. [PMID: 10332569] (Pubitemid 29121663)
    • (1998) Bailliere's Clinical Endocrinology and Metabolism , vol.12 , Issue.3 , pp. 501-506
    • Swerdloff, R.S.1    Wang, C.2
  • 12
    • 0034847204 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled, randomized clinical trial of transdermal dihydrotestosterone gel on muscular strength, mobility, and quality of life in older men with partial androgen deficiency
    • DOI 10.1210/jc.86.9.4078
    • Ly LP, Jimenez M, Zhuang TN, Celermajer DS, Conway AJ, Handelsman DJ. A double-blind, placebo-controlled, randomized clinical trial of transdermal dihydrotestosterone gel on muscular strength, mobility, and quality of life in older men with partial androgen deficiency. J Clin Endocrinol Metab. 2001;86: 4078-88. [PMID: 11549629] (Pubitemid 32848516)
    • (2001) Journal of Clinical Endocrinology and Metabolism , vol.86 , Issue.9 , pp. 4078-4088
    • Ly, L.P.1    Jimenez, M.2    Zhuang, T.N.3    Celermajer, D.S.4    Conway, A.J.5    Handelsman, D.J.6
  • 14
    • 65549087111 scopus 로고    scopus 로고
    • Selective androgen receptor modulators as function promoting therapies
    • PMID: 19357508
    • Bhasin S, Jasuja R. Selective androgen receptor modulators as function promoting therapies. Curr Opin Clin Nutr Metab Care. 2009;12:232-40. [PMID: 19357508]
    • (2009) Curr Opin Clin Nutr Metab Care , vol.12 , pp. 232-240
    • Bhasin, S.1    Jasuja, R.2
  • 15
    • 34548425622 scopus 로고    scopus 로고
    • Transperineal ultrasound for measurement of prostate volume: Validation against transrectal ultrasound
    • discussion 1379-80. [PMID: 17706715]
    • Griffiths KA, Ly LP, Jin B, Chan L, Handelsman DJ. Transperineal ultrasound for measurement of prostate volume: validation against transrectal ultrasound. J Urol. 2007;178:1375-9; discussion 1379-80. [PMID: 17706715]
    • (2007) J Urol , vol.178 , pp. 1375-1379
    • Griffiths, K.A.1    Ly, L.P.2    Jin, B.3    Chan, L.4    Handelsman, D.J.5
  • 16
    • 70349819876 scopus 로고    scopus 로고
    • Development and validation of a sensitive liquid chromatography-tandem mass spectrometry assay to simultaneously measure androgens and estrogens in serum without derivatization
    • PMID: 19747904
    • Harwood DT, Handelsman DJ. Development and validation of a sensitive liquid chromatography-tandem mass spectrometry assay to simultaneously measure androgens and estrogens in serum without derivatization. Clin Chim Acta. 2009;409:78-84. [PMID: 19747904]
    • (2009) Clin Chim Acta , vol.409 , pp. 78-84
    • Harwood, D.T.1    Handelsman, D.J.2
  • 17
    • 33747846300 scopus 로고    scopus 로고
    • Simultaneous determination of 12 steroids by isotope dilution liquid chromatography-photospray ionization tandem mass spectrometry
    • DOI 10.1016/j.cca.2006.03.034, PII S0009898106002099
    • Guo T, Taylor RL, Singh RJ, Soldin SJ. Simultaneous determination of 12 steroids by isotope dilution liquid chromatography-photospray ionization tandem mass spectrometry. Clin Chim Acta. 2006;372:76-82. [PMID: 16707118] (Pubitemid 44286760)
    • (2006) Clinica Chimica Acta , vol.372 , Issue.1-2 , pp. 76-82
    • Guo, T.1    Taylor, R.L.2    Singh, R.J.3    Soldin, S.J.4
  • 18
    • 43449100035 scopus 로고    scopus 로고
    • Rapid measurement of estrogens and their metabolites in human serum by liquid chromatographytandem mass spectrometry without derivatization
    • PMID: 18358240
    • Guo T, Gu J, Soldin OP, Singh RJ, Soldin SJ. Rapid measurement of estrogens and their metabolites in human serum by liquid chromatographytandem mass spectrometry without derivatization. Clin Biochem. 2008;41:736-41. [PMID: 18358240]
    • (2008) Clin Biochem , vol.41 , pp. 736-741
    • Guo, T.1    Gu, J.2    Soldin, O.P.3    Singh, R.J.4    Soldin, S.J.5
  • 20
    • 0023488498 scopus 로고
    • Methods for the assessment of human body composition: Traditional and new
    • PMID: 3310598
    • Lukaski HC. Methods for the assessment of human body composition: traditional and new. Am J Clin Nutr. 1987;46:537-56. [PMID: 3310598]
    • (1987) Am J Clin Nutr , vol.46 , pp. 537-556
    • Lukaski, H.C.1
  • 24
    • 0032974173 scopus 로고    scopus 로고
    • The Physical Activity Scale for the Elderly (PASE): Evidence for validity
    • DOI 10.1016/S0895-4356(99)00049-9, PII S0895435699000499
    • Washburn RA, McAuley E, Katula J, Mihalko SL, Boileau RA. The physical activity scale for the elderly (PASE): evidence for validity. J Clin Epidemiol. 1999;52:643-51. [PMID: 10391658] (Pubitemid 29281660)
    • (1999) Journal of Clinical Epidemiology , vol.52 , Issue.7 , pp. 643-651
    • Washburn, R.A.1    McAuley, E.2    Katula, J.3    Mihalko, S.L.4    Boileau, R.A.5
  • 25
    • 0642343055 scopus 로고    scopus 로고
    • A Simple Self-Report Diary for Assessing Psychosexual Function in Hypogonadal Men
    • Lee KK, Berman N, Alexander GM, Hull L, Swerdloff RS, Wang C. A simple self-report diary for assessing psychosexual function in hypogonadal men. J Androl. 2003;24:688-98. [PMID: 12954659] (Pubitemid 38133070)
    • (2003) Journal of Andrology , vol.24 , Issue.5 , pp. 688-698
    • Lee, K.K.1    Berman, N.2    Alexander, G.M.3    Hull, L.4    Swerdloff, R.S.5    Wang, C.6
  • 27
    • 0032534724 scopus 로고    scopus 로고
    • Selection models for repeated measurements with nonrandom dropout: An illustration of sensitivity
    • PMID: 9881418
    • Kenward MG. Selection models for repeated measurements with nonrandom dropout: an illustration of sensitivity. Stat Med. 1998;17:2723-32. [PMID: 9881418]
    • (1998) Stat Med , vol.17 , pp. 2723-2732
    • Kenward, M.G.1
  • 28
    • 0026782628 scopus 로고
    • Testosterone and 5 alpha-dihydrotestosterone interact differently with the androgen receptor to enhance transcription of the MMTV-CAT reporter gene
    • PMID: 1334007
    • Deslypere JP, Young M, Wilson JD, McPhaul MJ. Testosterone and 5 alpha-dihydrotestosterone interact differently with the androgen receptor to enhance transcription of the MMTV-CAT reporter gene. Mol Cell Endocrinol. 1992;88:15-22. [PMID: 1334007]
    • (1992) Mol Cell Endocrinol , vol.88 , pp. 15-22
    • Deslypere, J.P.1    Young, M.2    Wilson, J.D.3    McPhaul, M.J.4
  • 29
    • 0028809317 scopus 로고
    • Specificity of ligand-dependent androgen receptor stabilization: Receptor domain interactions influence ligand dissociation and receptor stability
    • PMID: 7776971
    • Zhou ZX, Lane MV, Kemppainen JA, French FS, Wilson EM. Specificity of ligand-dependent androgen receptor stabilization: receptor domain interactions influence ligand dissociation and receptor stability. Mol Endocrinol. 1995;9:208-18. [PMID: 7776971]
    • (1995) Mol Endocrinol , vol.9 , pp. 208-218
    • Zhou, Z.X.1    Lane, M.V.2    Kemppainen, J.A.3    French, F.S.4    Wilson, E.M.5
  • 30
    • 0033233311 scopus 로고    scopus 로고
    • 7alpha-methyl-19-nortestosterone, a synthetic androgen with high potency: Structure-activity comparisons with other androgens
    • DOI 10.1016/S0960-0760(99)00143-0, PII S0960076099001430
    • Kumar N, Crozat A, Li F, Catterall JF, Bardin CW, Sundaram K. 7alphamethyl-19-nortestosterone, a synthetic androgen with high potency: structureactivity comparisons with other androgens. J Steroid Biochem Mol Biol. 1999; 71:213-22. [PMID: 10704910] (Pubitemid 30125684)
    • (1999) Journal of Steroid Biochemistry and Molecular Biology , vol.71 , Issue.5-6 , pp. 213-222
    • Kumar, N.1    Crozat, A.2    Li, F.3    Catterall, J.F.4    Bardin, C.W.5    Sundaram, K.6
  • 31
    • 1642458222 scopus 로고    scopus 로고
    • Risks of Testosterone-Replacement Therapy and Recommendations for Monitoring
    • DOI 10.1056/NEJMra022251
    • Rhoden EL, Morgentaler A. Risks of testosterone-replacement therapy and recommendations for monitoring. N Engl J Med. 2004;350:482-92. [PMID: 14749457] (Pubitemid 38133769)
    • (2004) New England Journal of Medicine , vol.350 , Issue.5 , pp. 482-492
    • Rhoden, E.L.1    Morgentaler, A.2
  • 32
    • 0242390083 scopus 로고    scopus 로고
    • Managing the risks of prostate disease during testosterone replacement therapy in older men: Recommendations for a standardized monitoring plan
    • Bhasin S, Singh AB, Mac RP, Carter B, Lee MI, Cunningham GR. Managing the risks of prostate disease during testosterone replacement therapy in older men: recommendations for a standardized monitoring plan. J Androl. 2003;24: 299-311. [PMID: 12721204] (Pubitemid 39571784)
    • (2003) Journal of Andrology , vol.24 , Issue.3 , pp. 299-311
    • Bhasin, S.1    Singh, A.B.2    Mac, R.P.3    Carter, B.4    Lee, M.I.5    Cunningham, G.R.6
  • 33
    • 3042866315 scopus 로고    scopus 로고
    • Prostate-sparing effects in primates of the potent androgen 7alpha-methyl- 19-nortestosterone: A potential alternative to testosterone for androgen replacement and male contraception
    • Cummings DE, Kumar N, Bardin CW, Sundaram K, Bremner WJ. Prostate-sparing effects in primates of the potent androgen 7alpha-methyl-19- nortestosterone: a potential alternative to testosterone for androgen replacement and male contraception. J Clin Endocrinol Metab. 1998;83:4212-9. [PMID: 9851754] (Pubitemid 29100112)
    • (1998) Journal of Clinical Endocrinology and Metabolism , vol.83 , Issue.12 , pp. 4212-4219
    • Cummings, D.E.1    Kumar, N.2    Bardin, C.W.3    Sundaram, K.4    Bremner, W.J.5
  • 34
    • 0026772942 scopus 로고
    • The biological activity of 7 alpha-methyl-19-nortestosterone is not amplified in male reproductive tract as is that of testosterone
    • PMID: 1597164
    • Kumar N, Didolkar AK, Monder C, Bardin CW, Sundaram K. The biological activity of 7 alpha-methyl-19-nortestosterone is not amplified in male reproductive tract as is that of testosterone. Endocrinology. 1992;130:3677-83. [PMID: 1597164]
    • (1992) Endocrinology , vol.130 , pp. 3677-3683
    • Kumar, N.1    Didolkar, A.K.2    Monder, C.3    Bardin, C.W.4    Sundaram, K.5
  • 35
    • 44849091208 scopus 로고    scopus 로고
    • Dimethandrolone (7alpha,11beta-dimethyl-19-nortestosterone) and 11beta-methyl-19-nortestosterone are not converted to aromatic A-ring products in the presence of recombinant human aromatase
    • DOI 10.1016/j.jsbmb.2007.11.009, PII S0960076008000915
    • Attardi BJ, Pham TC, Radler LC, Burgenson J, Hild SA, Reel JR. Dimethandrolone (7alpha,11beta-dimethyl-19-nortestosterone) and 11beta-methyl-19-nortestosterone are not converted to aromatic A-ring products in the presence of recombinant human aromatase. J Steroid Biochem Mol Biol. 2008;110:214-22. [PMID: 18555683] (Pubitemid 351799973)
    • (2008) Journal of Steroid Biochemistry and Molecular Biology , vol.110 , Issue.3-5 , pp. 214-222
    • Attardi, B.J.1    Pham, T.C.2    Radler, L.M.3    Burgenson, J.4    Hild, S.A.5    Reel, J.R.6
  • 36
    • 74449091655 scopus 로고    scopus 로고
    • Mechanism of action of bolandiol (19-nortestosterone-3beta,17beta-diol), a unique anabolic steroid with androgenic, estrogenic, and progestational activities
    • PMID: 19941958
    • Attardi BJ, Page ST, Hild SA, Coss CC, Matsumoto AM. Mechanism of action of bolandiol (19-nortestosterone-3beta,17beta-diol), a unique anabolic steroid with androgenic, estrogenic, and progestational activities. J Steroid Biochem Mol Biol. 2010;118:151-61. [PMID: 19941958]
    • (2010) J Steroid Biochem Mol Biol , vol.118 , pp. 151-161
    • Attardi, B.J.1    Page, S.T.2    Hild, S.A.3    Coss, C.C.4    Matsumoto, A.M.5
  • 38
    • 38049005469 scopus 로고    scopus 로고
    • Effect of testosterone supplementation on functional mobility, cognition, and other parameters in older men: A randomized controlled trial
    • PMID: 18167405
    • Emmelot-Vonk MH, Verhaar HJ, Nakhai Pour HR, Aleman A, Lock TM, Bosch JL, et al. Effect of testosterone supplementation on functional mobility, cognition, and other parameters in older men: a randomized controlled trial. JAMA. 2008;299:39-52. [PMID: 18167405]
    • (2008) JAMA , vol.299 , pp. 39-52
    • Emmelot-Vonk, M.H.1    Verhaar, H.J.2    Nakhai Pour, H.R.3    Aleman, A.4    Lock, T.M.5    Bosch, J.L.6
  • 39
    • 0032100690 scopus 로고    scopus 로고
    • Intra- and inter-observer variability and reliability of prostate volume measurement via two-dimensional and three-dimensional ultrasound imaging
    • DOI 10.1016/S0301-5629(98)00039-8, PII S0301562998000398
    • Tong S, Cardinal HN, McLoughlin RF, Downey DB, Fenster A. Intra- and inter-observer variability and reliability of prostate volume measurement via two-dimensional and three-dimensional ultrasound imaging. Ultrasound Med Biol. 1998;24:673-81. [PMID: 9695270] (Pubitemid 28285203)
    • (1998) Ultrasound in Medicine and Biology , vol.24 , Issue.5 , pp. 673-681
    • Tong, S.1    Cardinal, H.N.2    McLoughlin, R.F.3    Downey, D.B.4    Fenster, A.5
  • 40
    • 0344393459 scopus 로고    scopus 로고
    • Limitations of direct estradiol and testosterone immunoassay kits
    • DOI 10.1016/j.steroids.2003.08.012
    • Stanczyk FZ, Cho MM, Endres DB, Morrison JL, Patel S, Paulson RJ. Limitations of direct estradiol and testosterone immunoassay kits. Steroids. 2003;68:1173-8. [PMID: 14643879] (Pubitemid 37476355)
    • (2003) Steroids , vol.68 , Issue.14 , pp. 1173-1178
    • Stanczyk, F.Z.1    Cho, M.M.2    Endres, D.B.3    Morrison, J.L.4    Patel, S.5    Paulson, R.J.6
  • 41
    • 0042868816 scopus 로고    scopus 로고
    • Testosterone measured by 10 immunoassays and by isotope-dilution gas chromatography-mass spectrometry in sera from 116 men, women, and children
    • DOI 10.1373/49.8.1381
    • Taieb J, Mathian B, Millot F, Patricot MC, Mathieu E, Queyrel N, et al. Testosterone measured by 10 immunoassays and by isotope-dilution gas chromatography-mass spectrometry in sera from 116 men, women, and children. Clin Chem. 2003;49:1381-95. [PMID: 12881456] (Pubitemid 36900626)
    • (2003) Clinical Chemistry , vol.49 , Issue.8 , pp. 1381-1395
    • Taieb, J.1    Mathian, B.2    Millot, F.3    Patricot, M.-C.4    Mathieu, E.5    Queyrel, N.6    Lacroix, I.7    Somma-Delpero, C.8    Boudou, P.9
  • 42
    • 1442327856 scopus 로고    scopus 로고
    • Measurement of Total Serum Testosterone in Adult Men: Comparison of Current Laboratory Methods Versus Liquid Chromatography-Tandem Mass Spectrometry
    • DOI 10.1210/jc.2003-031287
    • Wang C, Catlin DH, Demers LM, Starcevic B, Swerdloff RS. Measurement of total serum testosterone in adult men: comparison of current laboratory methods versus liquid chromatography-tandem mass spectrometry. J Clin Endocrinol Metab. 2004;89:534-43. [PMID: 14764758] (Pubitemid 38269854)
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , Issue.2 , pp. 534-543
    • Wang, C.1    Catlin, D.H.2    Demers, L.M.3    Starcevic, B.4    Swerdloff, R.S.5
  • 45
    • 0035652433 scopus 로고    scopus 로고
    • Natural history of benign prostatic hyperplasia
    • PMID: 11750242
    • Jacobsen SJ, Girman CJ, Lieber MM. Natural history of benign prostatic hyperplasia. Urology. 2001;58:5-16. [PMID: 11750242]
    • (2001) Urology , vol.58 , pp. 5-16
    • Jacobsen, S.J.1    Girman, C.J.2    Lieber, M.M.3
  • 46
    • 0028358995 scopus 로고
    • Prostate volume in testosterone-treated and untreated hypogonadal men in comparison to age-matched normal controls
    • Behre HM, Bohmeyer J, Nieschlag E. Prostate volume in testosterone-treated and untreated hypogonadal men in comparison to age-matched normal controls. Clin Endocrinol (Oxf). 1994;40:341-9. [PMID: 7514512] (Pubitemid 24194627)
    • (1994) Clinical Endocrinology , vol.40 , Issue.3 , pp. 341-349
    • Behre, H.M.1    Bohmeyer, J.2    Nieschlag, E.3
  • 47
    • 0031015948 scopus 로고    scopus 로고
    • Effects of age and sex hormones on transition and peripheral zone volumes of prostate and benign prostatic hyperplasia in twins
    • PMID: 9024256
    • Meikle AW, Stephenson RA, Lewis CM, Middleton RG. Effects of age and sex hormones on transition and peripheral zone volumes of prostate and benign prostatic hyperplasia in twins. J Clin Endocrinol Metab. 1997;82:571-5. [PMID: 9024256]
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 571-575
    • Meikle, A.W.1    Stephenson, R.A.2    Lewis, C.M.3    Middleton, R.G.4
  • 48
    • 0035724074 scopus 로고    scopus 로고
    • Effects of androgen deficiency and replacement on prostate zonal volumes
    • DOI 10.1046/j.1365-2265.2001.01240.x
    • Jin B, Conway AJ, Handelsman DJ. Effects of androgen deficiency and replacement on prostate zonal volumes. Clin Endocrinol (Oxf). 2001;54:437-45. [PMID: 11318778] (Pubitemid 34204179)
    • (2001) Clinical Endocrinology , vol.54 , Issue.4 , pp. 437-445
    • Jin, B.1    Conway, A.J.2    Handelsman, D.J.3
  • 49
    • 0038707532 scopus 로고    scopus 로고
    • Prostate volume and growth in testosterone-substituted hypogonadal men are dependent on the CAG repeat polymorphism of the androgen receptor gene: A longitudinal pharmacogenetic study
    • DOI 10.1210/jc.2002-021947
    • Zitzmann M, Depenbusch M, Gromoll J, Nieschlag E. Prostate volume and growth in testosterone-substituted hypogonadal men are dependent on the CAG repeat polymorphism of the androgen receptor gene: a longitudinal pharmacogenetic study. J Clin Endocrinol Metab. 2003;88: 2049-54. [PMID: 12727953] (Pubitemid 36549876)
    • (2003) Journal of Clinical Endocrinology and Metabolism , vol.88 , Issue.5 , pp. 2049-2054
    • Zitzmann, M.1    Depenbusch, M.2    Gromoll, J.3    Nieschlag, E.4
  • 50
    • 77954563168 scopus 로고    scopus 로고
    • Bone mineral density reference ranges for Australian men: Geelong Osteoporosis Study
    • PMID: 19707703
    • Henry MJ, Pasco JA, Korn S, Gibson JE, Kotowicz MA, Nicholson GC. Bone mineral density reference ranges for Australian men: Geelong Osteoporosis Study. Osteoporos Int. 2010;21:909-17. [PMID: 19707703]
    • (2010) Osteoporos Int , vol.21 , pp. 909-917
    • Henry, M.J.1    Pasco, J.A.2    Korn, S.3    Gibson, J.E.4    Kotowicz, M.A.5    Nicholson, G.C.6
  • 53
    • 0034521393 scopus 로고    scopus 로고
    • Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men
    • Falahati-Nini A, Riggs BL, Atkinson EJ, O'Fallon WM, Eastell R, Khosla S. Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men. J Clin Invest. 2000;106:1553-60. [PMID: 11120762] (Pubitemid 32038592)
    • (2000) Journal of Clinical Investigation , vol.106 , Issue.12 , pp. 1553-1560
    • Falahati-Nini, A.1    Riggs, B.L.2    Atkinson, E.J.3    O'Fallon, W.M.4    Eastell, R.5    Khosla, S.6
  • 54
    • 67449136137 scopus 로고    scopus 로고
    • History of aromatase: Saga of an important biological mediator and therapeutic target
    • PMID: 19389994
    • Santen RJ, Brodie H, Simpson ER, Siiteri PK, Brodie A. History of aromatase: saga of an important biological mediator and therapeutic target. Endocr Rev. 2009;30:343-75. [PMID: 19389994]
    • (2009) Endocr Rev , vol.30 , pp. 343-375
    • Santen, R.J.1    Brodie, H.2    Simpson, E.R.3    Siiteri, P.K.4    Brodie, A.5
  • 55
    • 0035716561 scopus 로고    scopus 로고
    • Cytochrome P450 aromatase (CYP19) in the nonhuman primate brain: Distribution, regulation, and functional significance
    • PMID: 11850231
    • Roselli CE, Resko JA. Cytochrome P450 aromatase (CYP19) in the nonhuman primate brain: distribution, regulation, and functional significance. J Steroid Biochem Mol Biol. 2001;79:247-53. [PMID: 11850231]
    • (2001) J Steroid Biochem Mol Biol , vol.79 , pp. 247-253
    • Roselli, C.E.1    Resko, J.A.2
  • 56
    • 0027161429 scopus 로고
    • Urinary hydroxypyridinium crosslinks of collagen as markers of bone resorption and estrogen efficacy in postmenopausal osteoporosis
    • Seibel MJ, Cosman F, Shen V, Gordon S, Dempster DW, Ratcliffe A, et al. Urinary hydroxypyridinium crosslinks of collagen as markers of bone resorption and estrogen efficacy in postmenopausal osteoporosis. J Bone Miner Res. 1993; 8:881-9. [PMID: 8352070] (Pubitemid 23191642)
    • (1993) Journal of Bone and Mineral Research , vol.8 , Issue.7 , pp. 881-889
    • Seibel, M.J.1    Cosman, F.2    Shen, V.3    Gordon, S.4    Dempster, D.W.5    Ratcliffe, A.6    Lindsay, R.7
  • 57
    • 58849164046 scopus 로고    scopus 로고
    • Molecular mechanisms in coupling of bone formation to resorption
    • PMID: 19191758
    • Martin T, Gooi JH, Sims NA. Molecular mechanisms in coupling of bone formation to resorption. Crit Rev Eukaryot Gene Expr. 2009;19:73-88. [PMID: 19191758]
    • (2009) Crit Rev Eukaryot Gene Expr , vol.19 , pp. 73-88
    • Martin, T.1    Gooi, J.H.2    Sims, N.A.3
  • 60
    • 55349088602 scopus 로고    scopus 로고
    • Changes in muscle mass, muscle strength, and power but not physical function are related to testosterone dose in healthy older men
    • PMID: 18795988
    • Storer TW, Woodhouse L, Magliano L, Singh AB, Dzekov C, Dzekov J, et al. Changes in muscle mass, muscle strength, and power but not physical function are related to testosterone dose in healthy older men. J Am Geriatr Soc. 2008;56:1991-9. [PMID: 18795988]
    • (2008) J Am Geriatr Soc , vol.56 , pp. 1991-1999
    • Storer, T.W.1    Woodhouse, L.2    Magliano, L.3    Singh, A.B.4    Dzekov, C.5    Dzekov, J.6
  • 62
    • 13944266300 scopus 로고    scopus 로고
    • Andropause: Invention, prevention, rejuvenation
    • PMID: 15734143
    • Handelsman DJ, Liu PY. Andropause: invention, prevention, rejuvenation. Trends Endocrinol Metab. 2005;16:39-45. [PMID: 15734143]
    • (2005) Trends Endocrinol Metab , vol.16 , pp. 39-45
    • Handelsman, D.J.1    Liu, P.Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.