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Volumn 5, Issue 7, 2010, Pages

A subset of osteoblasts expressing high endogenous levels of pparγ switches fate to adipocytes in the rat calvaria cell culture model

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; COMPLEMENTARY RNA; MESSENGER RNA; MYOD PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; ROSIGLITAZONE; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SOX9;

EID: 77955606279     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011782     Document Type: Article
Times cited : (26)

References (51)
  • 1
    • 2142652189 scopus 로고    scopus 로고
    • PPARΓ insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors
    • Akune T, Ohba S, Kamekura S, Yamaguchi M, Chung UI, et al. (2004) PPARΓ insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors. J Clin Invest 113: 846-855.
    • (2004) J Clin Invest , vol.113 , pp. 846-855
    • Akune, T.1    Ohba, S.2    Kamekura, S.3    Yamaguchi, M.4    Chung, U.I.5
  • 2
    • 0036830491 scopus 로고    scopus 로고
    • The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6
    • Akiyama H, Chaboissier MC, Martin JF, Schedl A, de Crombrugghe B (2002) The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. Genes Dev 16: 2813-2828.
    • (2002) Genes Dev , vol.16 , pp. 2813-2828
    • Akiyama, H.1    Chaboissier, M.C.2    Martin, J.F.3    Schedl, A.4    de Crombrugghe, B.5
  • 3
    • 21644434750 scopus 로고    scopus 로고
    • The circuitry of a master switch: MyoD and the regulation of skeletal muscle gene transcription
    • Tapscott SJ (2005) The circuitry of a master switch: MyoD and the regulation of skeletal muscle gene transcription. Development 132: 2685-2695.
    • (2005) Development , vol.132 , pp. 2685-2695
    • Tapscott, S.J.1
  • 4
    • 0015137446 scopus 로고
    • Osteoporosis and the replacement of cell populations of the marrow by adipose tissue. A quantitative study of 84 iliac bone biopsies
    • Meunier P, Aaron J, Edouard C, Vignon G (1971) Osteoporosis and the replacement of cell populations of the marrow by adipose tissue. A quantitative study of 84 iliac bone biopsies. Clin Orthop Relat Res 80: 147-154.
    • (1971) Clin Orthop Relat Res , vol.80 , pp. 147-154
    • Meunier, P.1    Aaron, J.2    Edouard, C.3    Vignon, G.4
  • 5
    • 0034842784 scopus 로고    scopus 로고
    • Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis
    • Justesen J, Stenderup K, Ebbesen EN, Mosekilde L, Steiniche T, et al. (2001) Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis. Biogerontology 2: 165-171.
    • (2001) Biogerontology , vol.2 , pp. 165-171
    • Justesen, J.1    Stenderup, K.2    Ebbesen, E.N.3    Mosekilde, L.4    Steiniche, T.5
  • 6
    • 0031953736 scopus 로고    scopus 로고
    • Human trabecular bone cells are able to express both osteoblastic and adipocytic phenotype: Implications for osteopenic disorders
    • Nuttall ME, Patton AJ, Olivera DL, Nadeau DP, Gowen M (1998) Human trabecular bone cells are able to express both osteoblastic and adipocytic phenotype: implications for osteopenic disorders. J Bone Miner Res 13:371-382.
    • (1998) J Bone Miner Res , vol.13 , pp. 371-382
    • Nuttall, M.E.1    Patton, A.J.2    Olivera, D.L.3    Nadeau, D.P.4    Gowen, M.5
  • 7
    • 0031709480 scopus 로고    scopus 로고
    • Reduced expression of interleukin-11 in bone marrow stromal cells of senescence-accelerated mice (SAMP6): Relationship to osteopenia with enhanced adipogenesis
    • Kodama Y, Takeuchi Y, Suzawa M, Fukumoto S, Murayama H, et al. (1998) Reduced expression of interleukin-11 in bone marrow stromal cells of senescence-accelerated mice (SAMP6): relationship to osteopenia with enhanced adipogenesis. J Bone Miner Res 13: 1370-1377.
    • (1998) J Bone Miner Res , vol.13 , pp. 1370-1377
    • Kodama, Y.1    Takeuchi, Y.2    Suzawa, M.3    Fukumoto, S.4    Murayama, H.5
  • 8
    • 14244250617 scopus 로고    scopus 로고
    • Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation
    • Ali AA, Weinstein RS, Stewart SA, Parfitt AM, Manolagas SC, et al. (2005) Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation. Endocrinology 146: 1226-1235.
    • (2005) Endocrinology , vol.146 , pp. 1226-1235
    • Ali, A.A.1    Weinstein, R.S.2    Stewart, S.A.3    Parfitt, A.M.4    Manolagas, S.C.5
  • 9
    • 0036090467 scopus 로고    scopus 로고
    • Divergent effects ofselective peroxisome proliferator-activated receptor-Γ 2 ligands on adipocyte versus osteoblast differentiation
    • Lecka-Czernik B, Moerman EJ, Grant DF, Lehmann JM, Manolagas SC, et al. (2002) Divergent effects ofselective peroxisome proliferator-activated receptor-Γ 2 ligands on adipocyte versus osteoblast differentiation. Endocrinology 143:2376-2384.
    • (2002) Endocrinology , vol.143 , pp. 2376-2384
    • Lecka-Czernik, B.1    Moerman, E.J.2    Grant, D.F.3    Lehmann, J.M.4    Manolagas, S.C.5
  • 10
    • 0033305164 scopus 로고    scopus 로고
    • Thiazolidi-nedione effects on glucocorticoid receptor-mediated gene transcription and differentiation in osteoblastic cells
    • Johnson TE, Vogel R, Rutledge SJ, Rodan G, Schmidt A (1999) Thiazolidi-nedione effects on glucocorticoid receptor-mediated gene transcription and differentiation in osteoblastic cells. Endocrinology 140: 3245-3254.
    • (1999) Endocrinology , vol.140 , pp. 3245-3254
    • Johnson, T.E.1    Vogel, R.2    Rutledge, S.J.3    Rodan, G.4    Schmidt, A.5
  • 12
    • 33845996557 scopus 로고    scopus 로고
    • Asymmetric cleavage of β-carotene yields a transcriptional repressor ofretinoid X receptor and peroxisome proliferator-activated receptor responses
    • Ziouzenkova O, Orasanu G, Sukhova G, Lau E, Berger JP, et al. (2007) Asymmetric cleavage of β-carotene yields a transcriptional repressor ofretinoid X receptor and peroxisome proliferator-activated receptor responses. Mol Endocrinol 21: 77-88.
    • (2007) Mol Endocrinol , vol.21 , pp. 77-88
    • Ziouzenkova, O.1    Orasanu, G.2    Sukhova, G.3    Lau, E.4    Berger, J.P.5
  • 15
    • 0842263981 scopus 로고    scopus 로고
    • The biology of peroxisome proliferator-activated receptors: Relationship with lipid metabolism and insulin sensitivity
    • Ferre P (2004) The biology of peroxisome proliferator-activated receptors: relationship with lipid metabolism and insulin sensitivity. Diabetes 53 Suppl 1:S43-50.
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 1
    • Ferre, P.1
  • 16
  • 17
    • 0036312788 scopus 로고    scopus 로고
    • Behavior of osteoblast, adipocyte, and myoblast markers in genome-wide expression analysis of mouse calvaria primary osteoblasts in vitro
    • Garcia T, Roman-Roman S, Jackson A, Theilhaber J, Connolly T, et al. (2002) Behavior of osteoblast, adipocyte, and myoblast markers in genome-wide expression analysis of mouse calvaria primary osteoblasts in vitro. Bone 31:205-211.
    • (2002) Bone , vol.31 , pp. 205-211
    • Garcia, T.1    Roman-Roman, S.2    Jackson, A.3    Theilhaber, J.4    Connolly, T.5
  • 18
    • 48349130853 scopus 로고    scopus 로고
    • The PPARΓ-selective ligand BRL-49653 differentially regulates the fate choices of rat calvaria versus rat bone marrow stromal cell populations
    • Hasegawa T, Oizumi K, Yoshiko Y, Tanne K, Maeda N, et al. (2008) The PPARΓ-selective ligand BRL-49653 differentially regulates the fate choices of rat calvaria versus rat bone marrow stromal cell populations. BMC Dev Biol 8: 71.
    • (2008) BMC Dev Biol , vol.8 , pp. 71
    • Hasegawa, T.1    Oizumi, K.2    Yoshiko, Y.3    Tanne, K.4    Maeda, N.5
  • 19
    • 0035236997 scopus 로고    scopus 로고
    • Regulation of osteoblast formation and function
    • Aubin JE (2001) Regulation of osteoblast formation and function. Rev Endocr Metab Disord 2: 81-94.
    • (2001) Rev Endocr Metab Disord , vol.2 , pp. 81-94
    • Aubin, J.E.1
  • 20
    • 0035027677 scopus 로고    scopus 로고
    • Individual osteoblasts in the developing calvaria express different gene repertoires
    • Candeliere GA, Liu F, Aubin JE (2001) Individual osteoblasts in the developing calvaria express different gene repertoires. Bone 28: 351-361.
    • (2001) Bone , vol.28 , pp. 351-361
    • Candeliere, G.A.1    Liu, F.2    Aubin, J.E.3
  • 21
    • 0035138914 scopus 로고    scopus 로고
    • Activated parathyroid hormone/parathyroid hormone-related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone
    • Calvi LM, Sims NA, Hunzelman JL, Knight MC, Giovannetti A, et al. (2001) Activated parathyroid hormone/parathyroid hormone-related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone. J Clin Invest 107: 277-286.
    • (2001) J Clin Invest , vol.107 , pp. 277-286
    • Calvi, L.M.1    Sims, N.A.2    Hunzelman, J.L.3    Knight, M.C.4    Giovannetti, A.5
  • 22
    • 33746471310 scopus 로고    scopus 로고
    • Side population (SP) cells isolated from fetal rat calvaria are enriched for bone, cartilage, adipose tissue and neural progenitors
    • Zhang S, Uchida S, Inoue T, Chan M, Mockler E, et al. (2006) Side population (SP) cells isolated from fetal rat calvaria are enriched for bone, cartilage, adipose tissue and neural progenitors. Bone 38: 662-670.
    • (2006) Bone , vol.38 , pp. 662-670
    • Zhang, S.1    Uchida, S.2    Inoue, T.3    Chan, M.4    Mockler, E.5
  • 23
    • 0025773462 scopus 로고
    • Positive and negative immunoselection for enrichment of two classes of osteoprogenitor cells
    • Turksen K, Aubin JE (1991) Positive and negative immunoselection for enrichment of two classes of osteoprogenitor cells. J Cell Biol 114: 373-384.
    • (1991) J Cell Biol , vol.114 , pp. 373-384
    • Turksen, K.1    Aubin, J.E.2
  • 24
    • 0034782842 scopus 로고    scopus 로고
    • The frequency of common progenitors for adipocytes and osteoblasts and of committed and restricted adipocyte and osteoblast progenitors in fetal rat calvaria cell populations
    • Bellows CG, Heersche JN (2001) The frequency of common progenitors for adipocytes and osteoblasts and of committed and restricted adipocyte and osteoblast progenitors in fetal rat calvaria cell populations. J Bone Miner Res 16:1983-1993.
    • (2001) J Bone Miner Res , vol.16 , pp. 1983-1993
    • Bellows, C.G.1    Heersche, J.N.2
  • 25
    • 0037650080 scopus 로고    scopus 로고
    • Global amplification polymerase chain reaction reveals novel transitional stages during osteoprogenitor differentiation
    • Liu F, Malaval L, Aubin JE (2003) Global amplification polymerase chain reaction reveals novel transitional stages during osteoprogenitor differentiation. J Cell Sci 116: 1787-1796.
    • (2003) J Cell Sci , vol.116 , pp. 1787-1796
    • Liu, F.1    Malaval, L.2    Aubin, J.E.3
  • 26
    • 2642674421 scopus 로고    scopus 로고
    • High fatty acid content in rabbit serum is responsible for the differentiation of osteoblasts into adipocyte-like cells
    • Diascro DD Jr, Vogel RL, Johnson TE, Witherup KM, Pitzenberger SM, et al. (1998) High fatty acid content in rabbit serum is responsible for the differentiation of osteoblasts into adipocyte-like cells. J Bone Miner Res 13: 96-106.
    • (1998) J Bone Miner Res , vol.13 , pp. 96-106
    • Diascro Jr., D.D.1    Vogel, R.L.2    Johnson, T.E.3    Witherup, K.M.4    Pitzenberger, S.M.5
  • 27
    • 33646508121 scopus 로고    scopus 로고
    • PPARα agonist fenofibrate improves diabetic nephropathy in db/db mice
    • Park CW, Zhang Y, Zhang X, Wu J, Chen L, et al. (2006) PPARα agonist fenofibrate improves diabetic nephropathy in db/db mice. Kidney Int 69: 1511-1517.
    • (2006) Kidney Int , vol.69 , pp. 1511-1517
    • Park, C.W.1    Zhang, Y.2    Zhang, X.3    Wu, J.4    Chen, L.5
  • 28
    • 0038607705 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor-Γ inhibits the Runx2-mediated transcription of osteocalcin in osteoblasts
    • Jeon MJ, Kim JA, Kwon SH, Kim SW, Park KS, et al. (2003) Activation of peroxisome proliferator-activated receptor-Γ inhibits the Runx2-mediated transcription of osteocalcin in osteoblasts. JBiol Chem 278: 23270-23277.
    • (2003) J Biol Chem , vol.278 , pp. 23270-23277
    • Jeon, M.J.1    Kim, J.A.2    Kwon, S.H.3    Kim, S.W.4    Park, K.S.5
  • 30
    • 11844291416 scopus 로고    scopus 로고
    • Ectopic overexpression of adipogenic transcription factors induces transdifferentiation of MC3T3-E1 osteoblasts
    • Kim SW, Her SJ, Kim SY, Shin CS (2005) Ectopic overexpression of adipogenic transcription factors induces transdifferentiation of MC3T3-E1 osteoblasts. Biochem Biophys Res Commun 327: 811-819.
    • (2005) Biochem Biophys Res Commun , vol.327 , pp. 811-819
    • Kim, S.W.1    Her, S.J.2    Kim, S.Y.3    Shin, C.S.4
  • 31
    • 0033567835 scopus 로고    scopus 로고
    • Kinetics of osteoprogenitor proliferation and osteoblast differentiation in vitro
    • Malaval L, Liu F, Roche P, Aubin JE (1999) Kinetics of osteoprogenitor proliferation and osteoblast differentiation in vitro. JCell Biochem 74: 616-627.
    • (1999) J Cell Biochem , vol.74 , pp. 616-627
    • Malaval, L.1    Liu, F.2    Roche, P.3    Aubin, J.E.4
  • 32
    • 0034616069 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor activators modulate the osteoblastic maturation of MC3T3-E1 preosteoblasts
    • Jackson SM, Demer LL (2000) Peroxisome proliferator-activated receptor activators modulate the osteoblastic maturation of MC3T3-E1 preosteoblasts. FEBS Lett 471: 119-124.
    • (2000) FEBS Lett , vol.471 , pp. 119-124
    • Jackson, S.M.1    Demer, L.L.2
  • 33
    • 33744497272 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor N-terminal domain controls isotype-selective gene expression and adipogenesis
    • Hummasti S, Tontonoz P (2006) The peroxisome proliferator-activated receptor N-terminal domain controls isotype-selective gene expression and adipogenesis. Mol Endocrinol 20: 1261-1275.
    • (2006) Mol Endocrinol , vol.20 , pp. 1261-1275
    • Hummasti, S.1    Tontonoz, P.2
  • 34
    • 0034915161 scopus 로고    scopus 로고
    • Troglitazone treatment increases bone marrow adipose tissue volume but does not affect trabecular bone volume in mice
    • Tornvig L, Mosekilde LI, Justesen J, Falk E, Kassem M (2001) Troglitazone treatment increases bone marrow adipose tissue volume but does not affect trabecular bone volume in mice. Calcif Tissue Int 69: 46-50.
    • (2001) Calcif Tissue Int , vol.69 , pp. 46-50
    • Tornvig, L.1    Mosekilde, L.I.2    Justesen, J.3    Falk, E.4    Kassem, M.5
  • 35
    • 29344470714 scopus 로고    scopus 로고
    • Netoglitazone is a PPAR-Γ ligand with selective effects on bone and fat
    • Lazarenko OP, Rzonca SO, Suva LJ, Lecka-Czernik B (2006) Netoglitazone is a PPAR-Γ ligand with selective effects on bone and fat. Bone 38: 74-84.
    • (2006) Bone , vol.38 , pp. 74-84
    • Lazarenko, O.P.1    Rzonca, S.O.2    Suva, L.J.3    Lecka-Czernik, B.4
  • 36
    • 0028871780 scopus 로고
    • Transdifferentiation of myoblasts by the adipogenic transcription factors PPARΓ and C/EBPα
    • Hu E, Tontonoz P, Spiegelman BM (1995) Transdifferentiation of myoblasts by the adipogenic transcription factors PPARΓ and C/EBPα. Proc Natl Acad Sci U S A 92: 9856-9860.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 9856-9860
    • Hu, E.1    Tontonoz, P.2    Spiegelman, B.M.3
  • 37
    • 14844334826 scopus 로고    scopus 로고
    • Dual-regulated expression of C/EBP-a and BMP-2 enables differential differentiation of C2C12 cells into adipocytes and osteoblasts
    • Fux C, Mitta B, Kramer BP, Fussenegger M (2004) Dual-regulated expression of C/EBP-a and BMP-2 enables differential differentiation of C2C12 cells into adipocytes and osteoblasts. Nucleic Acids Res 32: e1.
    • (2004) Nucleic Acids Res , vol.32
    • Fux, C.1    Mitta, B.2    Kramer, B.P.3    Fussenegger, M.4
  • 38
    • 0037059765 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding proteins (C/EBP)β and δ activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression
    • Gutierrez S, Javed A, Tennant DK, van Rees M, Montecino M, et al. (2002) CCAAT/enhancer-binding proteins (C/EBP)β and δ activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression. J Biol Chem 277: 1316-1323.
    • (2002) J Biol Chem , vol.277 , pp. 1316-1323
    • Gutierrez, S.1    Javed, A.2    Tennant, D.K.3    van Rees, M.4    Montecino, M.5
  • 39
    • 29244474912 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor Γ and the regulation of adipocyte function: Lessons from human genetic studies
    • Gurnell M (2005) Peroxisome proliferator-activated receptor Γ and the regulation of adipocyte function: lessons from human genetic studies. Best Pract Res Clin Endocrinol Metab 19: 501-523.
    • (2005) Best Pract Res Clin Endocrinol Metab , vol.19 , pp. 501-523
    • Gurnell, M.1
  • 40
    • 0041766341 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor-Γ inhibits differentiation of preosteoblasts
    • Khan E, Abu-Amer Y (2003) Activation of peroxisome proliferator-activated receptor-Γ inhibits differentiation of preosteoblasts. J Lab Clin Med 142: 29-34.
    • (2003) J Lab Clin Med , vol.142 , pp. 29-34
    • Khan, E.1    Abu-Amer, Y.2
  • 41
  • 42
    • 18644384149 scopus 로고    scopus 로고
    • Genetic analysis of adipogenesis through peroxisome proliferator-activated receptor Γ isoforms
    • Mueller E, Drori S, Aiyer A, Yie J, Sarraf P, et al. (2002) Genetic analysis of adipogenesis through peroxisome proliferator-activated receptor Γ isoforms. J Biol Chem 277: 41925-41930.
    • (2002) J Biol Chem , vol.277 , pp. 41925-41930
    • Mueller, E.1    Drori, S.2    Aiyer, A.3    Yie, J.4    Sarraf, P.5
  • 43
    • 23944469952 scopus 로고    scopus 로고
    • Expression of PPARΓ and β/δ in human primary osteoblastic cells: Influence of polyunsaturated fatty acids
    • Maurin AC, Chavassieux PM, Meunier PJ (2005) Expression of PPARΓ and β/δ in human primary osteoblastic cells: influence of polyunsaturated fatty acids. Calcif Tissue Int 76: 385-392.
    • (2005) Calcif Tissue Int , vol.76 , pp. 385-392
    • Maurin, A.C.1    Chavassieux, P.M.2    Meunier, P.J.3
  • 44
    • 42749083244 scopus 로고    scopus 로고
    • Evidence for multiple peroxisome proliferator-activated receptor Γ transcripts in bone: Fine-tuning by hormonal regulation and mRNA stability
    • Bruedigam C, Koedam M, Chiba H, Eijken M, van Leeuwen JP (2008) Evidence for multiple peroxisome proliferator-activated receptor Γ transcripts in bone: fine-tuning by hormonal regulation and mRNA stability. FEBS Lett 582:1618-1624.
    • (2008) FEBS Lett , vol.582 , pp. 1618-1624
    • Bruedigam, C.1    Koedam, M.2    Chiba, H.3    Eijken, M.4    van Leeuwen, J.P.5
  • 45
    • 61449123058 scopus 로고    scopus 로고
    • PPARΓ2 nuclear receptor controls multiple regulatory pathways of osteoblast differentiation from marrow mesenchymal stem cells
    • Shockley KR, Lazarenko OP, Czernik PJ, Rosen CJ, Churchill GA, et al. (2009) PPARΓ2 nuclear receptor controls multiple regulatory pathways of osteoblast differentiation from marrow mesenchymal stem cells. J Cell Biochem 106:232-246.
    • (2009) J Cell Biochem , vol.106 , pp. 232-246
    • Shockley, K.R.1    Lazarenko, O.P.2    Czernik, P.J.3    Rosen, C.J.4    Churchill, G.A.5
  • 46
    • 0022569874 scopus 로고
    • Mineralized bone nodules formed in vitro from enzymatically released rat calvaria cell populations
    • Bellows CG, Aubin JE, Heersche JN, Antosz ME (1986) Mineralized bone nodules formed in vitro from enzymatically released rat calvaria cell populations. Calcif Tissue Int 38: 143-154.
    • (1986) Calcif Tissue Int , vol.38 , pp. 143-154
    • Bellows, C.G.1    Aubin, J.E.2    Heersche, J.N.3    Antosz, M.E.4
  • 47
    • 0041920579 scopus 로고    scopus 로고
    • Stanniocalcin 1 stimulates osteoblast differentiation in rat calvaria cell cultures
    • Yoshiko Y, Maeda N, Aubin JE (2003) Stanniocalcin 1 stimulates osteoblast differentiation in rat calvaria cell cultures. Endocrinology 144: 4134-4143.
    • (2003) Endocrinology , vol.144 , pp. 4134-4143
    • Yoshiko, Y.1    Maeda, N.2    Aubin, J.E.3
  • 48
    • 33745514431 scopus 로고    scopus 로고
    • Activation of Sirt1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells
    • Backesjo CM, Li Y, Lindgren U, Haldosen LA (2006) Activation of Sirt1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells. JBone Miner Res 21: 993-1002.
    • (2006) J Bone Miner Res , vol.21 , pp. 993-1002
    • Backesjo, C.M.1    Li, Y.2    Lindgren, U.3    Haldosen, L.A.4
  • 49
    • 0032500752 scopus 로고    scopus 로고
    • Changes in leptin expression are not associated with corresponding changes in CCAAT/enhancer binding protein-α
    • Sloop KW, Surface PL, Heiman ML, Slieker LJ (1998) Changes in leptin expression are not associated with corresponding changes in CCAAT/enhancer binding protein-α. Biochem Biophys Res Commun 251: 142-147.
    • (1998) Biochem Biophys Res Commun , vol.251 , pp. 142-147
    • Sloop, K.W.1    Surface, P.L.2    Heiman, M.L.3    Slieker, L.J.4
  • 50
    • 0031438080 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding protein 8 activates insulin-like growth factor-I gene transcription in osteoblasts. Identification of a novel cyclic AMP signaling pathway in bone
    • Umayahara Y, Ji C, Centrella M, Rotwein P, McCarthy TL (1997) CCAAT/enhancer-binding protein 8 activates insulin-like growth factor-I gene transcription in osteoblasts. Identification of a novel cyclic AMP signaling pathway in bone. J Biol Chem 272: 31793-31800.
    • (1997) J Biol Chem , vol.272 , pp. 31793-31800
    • Umayahara, Y.1    Ji, C.2    Centrella, M.3    Rotwein, P.4    McCarthy, T.L.5
  • 51
    • 0037462931 scopus 로고    scopus 로고
    • A faithful method for PCR-mediated global mRNA amplification and its integration into microarray analysis on laser-captured cells
    • Aoyagi K, Tatsuta T, Nishigaki M, Akimoto S, Tanabe C, et al. (2003) A faithful method for PCR-mediated global mRNA amplification and its integration into microarray analysis on laser-captured cells. Biochem Biophys Res Commun 300:915-920.
    • (2003) Biochem Biophys Res Commun , vol.300 , pp. 915-920
    • Aoyagi, K.1    Tatsuta, T.2    Nishigaki, M.3    Akimoto, S.4    Tanabe, C.5


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