Estrogen Sulfotransferase Inhibits Adipocyte Differentiation

Molecular Endocrinology

Volumn 25, Issue 9, 2011, Pages 1612-1623

  Wada, Taira ^a   Ihunnah, Chibueze A ^a   Gao, Jie ^a   Chai, Xiaojuan ^a,c   Zeng, Su ^c   Philips, Brian J ^b   Rubin, J Peter ^b   Marra, Kacey G ^b   Xie, Wen ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN SULFOTRANSFERASE; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3;

ADIPOCYTE; ADIPOGENESIS; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CELL ISOLATION; ENZYME ACTIVITY; FEMALE; GENE OVEREXPRESSION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROADIPOCYTE; SIGNAL TRANSDUCTION; WHITE ADIPOSE TISSUE;

3T3-L1 CELLS; ADIPOCYTES; ADIPOGENESIS; ADIPOSE TISSUE; ANIMALS; CELL DIFFERENTIATION; CELL SIZE; ENZYME ACTIVATION; ESTRADIOL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INSULIN; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PPAR GAMMA; RNA, MESSENGER; SIGNAL TRANSDUCTION; SULFOTRANSFERASES;

MUS; MUS MUSCULUS;

EID: 80052280840     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2011-1089     Document Type: Article

References (45)

1. Hu E, Kim JB, Sarraf P, Spiegelman BM 1996 Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPAR_. Science 274:2100-2103
2. MacDougald OA, Cornelius P, Liu R, Lane MD 1995 Insulin regulates transcription of the CCAAT/enhancer binding protein (C/ EBP) α, β, and δ genes in fully-differentiated 3T3-L1 adipocytes. J Biol Chem 270:647-654
3. Tontonoz P, Hu E, Spiegelman BM 1994 Stimulation of adipogenesis in fibroblasts by PPAR _ 2, a lipid-activated transcription factor. Cell 79:1147-1156
4. Wu Z, Rosen ED, Brun R, Hauser S, Adelmant G, Troy AE, McKeon C, Darlington GJ, Spiegelman BM 1999 Cross-regulation of C/EBP _ and PPAR γ controls the transcriptional pathway of adipogenesis and insulin sensitivity. Mol Cell 3:151-158
5. Rosen ED, Walkey CJ, Puigserver P, Spiegelman BM 2000 Transcriptional regulation of adipogenesis. Genes Dev 14:1293-1307
6. Gordon GB, Newitt JA, Shantz LM, Weng DE, Talalay P 1986 Inhibition of the conversion of 3T3 fibroblast clones to adipocytes by dehydroepiandrosterone and related anticarcinogenic steroids. Cancer Res 46:3389-3395
7. Heine PA, Taylor JA, Iwamoto GA, Lubahn DB, Cooke PS 2000 Increased adipose tissue in male and female estrogen receptor-α knockout mice. Proc Natl Acad Sci USA 97:12729-12734
8. Naaz A, Zakroczymski M, Heine P, Taylor J, Saunders P, Lubahn D, Cooke PS 2002 Effect of ovariectomy on adipose tissue of mice in the absence of estrogen receptor α (ER α): a potential role for estrogen receptor β (ER β). Horm Metab Res 34:758-763
9. Fisher CR, Graves KH, Parlow AF, Simpson ER 1998 Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene. Proc Natl Acad Sci USA 95:6965-6970
10. Takeda K, Toda K, Saibara T, Nakagawa M, Saika K, Onishi T, Sugiura T, Shizuta Y 2003 Progressive development of insulin resistance phenotype in male mice with complete aromatase (CYP19) deficiency. J Endocrinol 176:237-246
11. Palin SL, McTernan PG, Anderson LA, Sturdee DW, Barnett AH, Kumar S 2003 17β-Estradiol and anti-estrogen ICI:compound 182,780 regulate expression of lipoprotein lipase and hormonesensitive lipase in isolated subcutaneous abdominal adipocytes. Metabolism 52:383-388
12. Pedersen SB, Kristensen K, Hermann PA, Katzenellenbogen JA, Richelsen B 2004 Estrogen controls lipolysis by up-regulating α 2Aadrenergic receptors directly in human adipose tissue through the estrogen receptor α. Implications for the female fat distribution. J Clin Endocrinol Metab 89:1869-1878
13. Muraki K, Okuya S, Tanizawa Y 2006 Estrogen receptor α regulates insulin sensitivity through IRS-1 tyrosine phosphorylation in mature 3T3-L1 adipocytes. Endocr J 53:841-851
14. Dieudonne MN, Pecquery R, Leneveu MC, Giudicelli Y 2000 Opposite effects of androgens and estrogens on adipogenesis in rat preadipocytes: evidence for sex and site-related specificities and possible involvement of insulin-like growth factor 1 receptor and peroxisome proliferator-activated receptor γ2. Endocrinology 141: 649-656
15. Song WC, Moore R, McLachlan JA, Negishi M 1995 Molecular characterization of a testis-specific estrogen sulfotransferase and aberrant liver expression in obese and diabetogenic C57BL/KsJdb/ db mice. Endocrinology 136:2477-2484
16. Gong H, Jarzynka MJ, Cole TJ, Lee JH, Wada T, Zhang B, Gao J, Song WC, DeFranco DB, Cheng SY, Xie W 2008 Glucocorticoids antagonize estrogens by glucocorticoid receptor-mediated activation of estrogen sulfotransferase. Cancer Res 68:7386-7393
17. Gong H, Guo P, Zhai Y, Zhou J, Uppal H, Jarzynka MJ, Song WC, Cheng SY, Xie W 2007 Estrogen deprivation and inhibition of breast cancer growth in vivo through activation of the orphan nuclear receptor liver X receptor. Mol Endocrinol 21:1781-1790
18. Kang HS, Angers M, Beak JY, Wu X, Gimble JM, Wada T, Xie W, Collins JB, Grissom SF, Jetten AM 2007 Gene expression profiling reveals a regulatory role for RORα andRORγ in phase I and phase II metabolism. Physiol Genomics 31:281-294
19. Wada T, Kang HS, Angers M, Gong H, Bhatia S, Khadem S, Ren S, Ellis E, Strom SC, Jetten AM, Xie W 2008 Identification of oxysterol 7α-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor α (RORα) (NR1F1) target gene and a functional cross-talk between RORα and liver X receptor (NR1H3). Mol Pharmacol 73:891-899
20. Tong MH, Christenson LK, Song WC 2004 Aberrant cholesterol transport and impaired steroidogenesis in Leydig cells lacking estrogen sulfotransferase. Endocrinology 145:2487-2497
21. Tong MH, Jiang H, Liu P, Lawson JA, Brass LF, Song WC 2005 Spontaneous fetal loss caused by placental thrombosis in estrogen sulfotransferase-deficient mice. Nat Med 11:153-159
22. Tong MH, Song WC 2002 Estrogen sulfotransferase: discrete and androgen-dependent expression in the male reproductive tract and demonstration of an in vivo function in the mouse epididymis. Endocrinology 143:3144-3151
23. Khor VK, Tong MH, Qian Y, Song WC 2008 Gender-specific expression and mechanism of regulation of estrogen sulfotransferase in adipose tissues of the mouse. Endocrinology 149:5440-5448
24. Font de Mora J, Porras A, Ahn N, Santos E 1997 Mitogenactivated protein kinase activation is not necessary for, but antagonizes, 3T3-L1 adipocytic differentiation. Mol Cell Biol 17: 6068-6075
25. Sale EM, Atkinson PG, Sale GJ 1995 Requirement of MAP kinase for differentiation of fibroblasts to adipocytes, for insulin activation of p90 S6 kinase and for insulin or serum stimulation of DNA synthesis. EMBO J 14:674-684
26. Sekimoto H, Boney CM 2003 C-terminal Src kinase (CSK) modulates insulin-like growth factor-I signaling through Src in 3T3-L1 differentiation. Endocrinology 144:2546-2552
27. Magun R, Burgering BM, Coffer PJ, Pardasani D, Lin Y, Chabot J, Sorisky A 1996 Expression of a constitutively activated form of protein kinase B (c-Akt) in 3T3-L1 preadipose cells causes spontaneous differentiation. Endocrinology 137:3590-3593
28. Gagnon A, Chen CS, Sorisky A 1999 Activation of protein kinase B and induction of adipogenesis by insulin in 3T3-L1 preadipocytes: contribution of phosphoinositide-3,4,5-trisphosphate versus phosphoinositide-3,4-bisphosphate. Diabetes 48:691-698
29. Okamoto M, Hayashi T, Kono S, Inoue G, Kubota M, Okamoto M, Kuzuya H, Imura H 1993 Specific activity of phosphatidylinositol 3-kinase is increased by insulin stimulation. Biochem J 290: 327-333
30. Shimizu S, Maegawa H, Egawa K, Shi K, Bryer-Ash M, Kashiwagi A 2002 Mechanism for differential effect of protein-tyrosine phosphatase 1B on Akt versus mitogen-activated protein kinase in 3T3-L1 adipocytes. Endocrinology 143:4563-4569
31. Wellen KE, Fucho R, Gregor MF, Furuhashi M, Morgan C, Lindstad T, Vaillancourt E, Gorgun CZ, Saatcioglu F, Hotamisligil GS 2007 Coordinated regulation of nutrient and inflammatory responses by STAMP2 is essential for metabolic homeostasis. Cell 129:537-548
32. Komatsu K, Driscoll WJ, Koh YC, Strott CA 1994 A P-loop related motif (GxxGxxK) highly conserved in sulfotransferases is required for binding the activated sulfate donor. Biochem Biophys Res Commun 204:1178-1185
33. Phrakonkham P, Viengchareun S, Belloir C, Lombès M, Artur Y, Canivenc-Lavier MC 2008 Dietary xenoestrogens differentially impair 3T3-L1 preadipocyte differentiation and persistently affect leptin synthesis. J Steroid Biochem Mol Biol 110:95-103
34. Chan SS, Schedlich LJ, Twigg SM, Baxter RC 2009 Inhibition of adipocyte differentiation by insulin-like growth factor-binding protein-3. Am J Physiol Endocrinol Metab 296:E654-E663
35. Falany JL, Macrina N, Falany CN 2002 Regulation of MCF-7 breast cancer cell growth by β-estradiol sulfation. Breast Cancer Res Treat 74:167-176
36. Homma H, Kurachi H, Nishio Y, Takeda T, Yamamoto T, Adachi K, Morishige K, Ohmichi M, Matsuzawa Y, Murata Y 2000 Estrogen suppresses transcription of lipoprotein lipase gene. Existence of a unique estrogen response element on the lipoprotein lipase promoter. J Biol Chem 275:11404-11411
37. Lea-Currie YR, Wen P, McIntosh MK 1998 Dehydroepiandrosterone reduces proliferation and differentiation of 3T3-L1 preadipocytes. Biochem Biophys Res Commun 248:497-504
38. Ying H, Araki O, Furuya F, Kato Y, Cheng SY 2007 Impaired adipogenesis caused by a mutated thyroid hormone α1 receptor. Mol Cell Biol 27:2359-2371
39. Singh R, Artaza JN, Taylor WE, Braga M, Yuan X, Gonzalez-Cadavid NF, Bhasin S 2006 Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: nuclear translocation of androgen receptor complex with β-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors. Endocrinology 147:141-154
40. Smas CM, Chen L, Zhao L, Latasa MJ, Sul HS 1999 Transcriptional repression of pref-1 by glucocorticoids promotes 3T3-L1 adipocyte differentiation. J Biol Chem 274:12632-12641
41. Khor V, Dhir R, Yin X, Ahima RS, Song WC 2010 Estrogen sulfotransferase regulates body fat and glucose homeostasis in female mice. Am J Physiol Endocrinol Metab 299:E657-E664
42. D'Eon TM, Souza SC, Aronovitz M, Obin MS, Fried SK, Greenberg AS 2005 Estrogen regulation of adiposity and fuel partitioning. Evidence of genomic and non-genomic regulation of lipogenic and oxidative pathways. J Biol Chem 280:35983-35991
43. Qian YM, Sun XJ, Tong MH, Li XP, Richa J, Song WC 2001 Targeted disruption of the mouse estrogen sulfotransferase gene reveals a role of estrogen metabolism in intracrine and paracrine estrogen regulation. Endocrinology 142:5342-5350
44. Ruan H, Zarnowski MJ, Cushman SW, Lodish HF 2003 Standard isolation of primary adipose cells from mouse epididymal fat pads induces inflammatory mediators and down-regulates adipocyte genes. J Biol Chem 278:47585-47593
45. Sewter CP, Blows F, Vidal-Puig A, O'Rahilly S 2002 Regional differences in the response of human pre-adipocytes to PPARγ and RXRα agonists. Diabetes 51:718-723