메뉴 건너뛰기




Volumn 85, Issue 17, 2011, Pages 8680-8688

Parasite-mediated upregulation of NK cell-derived gamma interferon protects against severe highly pathogenic H5N1 influenza virus infection

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 6; PARASITE ANTIGEN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 80052275302     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.05142-11     Document Type: Article
Times cited : (23)

References (52)
  • 1
    • 0029836716 scopus 로고    scopus 로고
    • Functionally distinct T cells in three compartments of the respiratory tract after influenza virus infection
    • Baumgarth, N., and A. Kelso. 1996. Functionally distinct T cells in three compartments of the respiratory tract after influenza virus infection. Eur. J. Immunol. 26:2189-2197.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2189-2197
    • Baumgarth, N.1    Kelso, A.2
  • 2
    • 77957347769 scopus 로고    scopus 로고
    • Inhibition of hepatitis B virus DNA replication by a thermostable interferon-gamma variant
    • Brunelle, M. N., et al. 2010. Inhibition of hepatitis B virus DNA replication by a thermostable interferon-gamma variant. Antivir. Ther. 15:861-869.
    • (2010) Antivir. Ther. , vol.15 , pp. 861-869
    • Brunelle, M.N.1
  • 3
    • 67949117178 scopus 로고    scopus 로고
    • Flu: vaccinate to cut risk of chimaeric virus emerging
    • Capua, I., and G. Cattoli. 2009. Flu: vaccinate to cut risk of chimaeric virus emerging. Nature 460:571.
    • (2009) Nature , vol.460 , pp. 571
    • Capua, I.1    Cattoli, G.2
  • 4
    • 78449246342 scopus 로고    scopus 로고
    • Transforming growth factor-beta: activation by neuraminidase and role in highly pathogenic H5N1 influenza pathogenesis
    • Carlson, C. M., et al. 2010. Transforming growth factor-beta: activation by neuraminidase and role in highly pathogenic H5N1 influenza pathogenesis. PLoS Pathog. 6:e1001136.
    • (2010) PLoS Pathog , vol.6
    • Carlson, C.M.1
  • 5
    • 71949097546 scopus 로고    scopus 로고
    • Isolation of Toxoplasma gondii development mutants identifies a potential proteophosphoglycan that enhances cyst wall formation
    • Craver, M. P., P. J. Rooney, and L. J. Knoll. 2010. Isolation of Toxoplasma gondii development mutants identifies a potential proteophosphoglycan that enhances cyst wall formation. Mol. Biochem. Parasitol. 169:120-123.
    • (2010) Mol. Biochem. Parasitol. , vol.169 , pp. 120-123
    • Craver, M.P.1    Rooney, P.J.2    Knoll, L.J.3
  • 6
    • 0345016346 scopus 로고    scopus 로고
    • From cells to signaling cascades: manipulation of innate immunity by Toxoplasma gondii
    • Denkers, E. Y. 2003. From cells to signaling cascades: manipulation of innate immunity by Toxoplasma gondii. FEMS Immunol. Med. Microbiol. 39:193-203.
    • (2003) FEMS Immunol. Med. Microbiol. , vol.39 , pp. 193-203
    • Denkers, E.Y.1
  • 7
    • 0027204623 scopus 로고
    • Bone marrow macrophages process exogenous Toxoplasma gondii polypeptides for recognition by parasite-specific cytolytic T lymphocytes
    • Denkers, E. Y., R. T. Gazzinelli, S. Hieny, P. Caspar, and A. Sher. 1993. Bone marrow macrophages process exogenous Toxoplasma gondii polypeptides for recognition by parasite-specific cytolytic T lymphocytes. J. Immunol. 150:517-526.
    • (1993) J. Immunol. , vol.150 , pp. 517-526
    • Denkers, E.Y.1    Gazzinelli, R.T.2    Hieny, S.3    Caspar, P.4    Sher, A.5
  • 8
    • 0027491644 scopus 로고
    • Emergence of NK1.1+ cells as effectors of IFN-gamma dependent immunity to Toxoplasma gondii in MHC class I-deficient mice
    • Denkers, E. Y., R. T. Gazzinelli, D. Martin, and A. Sher. 1993. Emergence of NK1.1+ cells as effectors of IFN-gamma dependent immunity to Toxoplasma gondii in MHC class I-deficient mice. J. Exp. Med. 178:1465-1472.
    • (1993) J. Exp. Med. , vol.178 , pp. 1465-1472
    • Denkers, E.Y.1    Gazzinelli, R.T.2    Martin, D.3    Sher, A.4
  • 9
    • 0032128434 scopus 로고    scopus 로고
    • Advances in the life cycle of Toxoplasma gondii
    • Dubey, J. P. 1998. Advances in the life cycle of Toxoplasma gondii. Int. J. Parasitol. 28:1019-1024.
    • (1998) Int. J. Parasitol. , vol.28 , pp. 1019-1024
    • Dubey, J.P.1
  • 10
    • 65549130101 scopus 로고    scopus 로고
    • A new player in a deadly game: influenza viruses and the PI3K/Akt signalling pathway
    • Ehrhardt, C., and S. Ludwig. 2009. A new player in a deadly game: influenza viruses and the PI3K/Akt signalling pathway. Cell. Microbiol. 11:863-871.
    • (2009) Cell. Microbiol. , vol.11 , pp. 863-871
    • Ehrhardt, C.1    Ludwig, S.2
  • 11
    • 54049155727 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor (MIF) is critical for the host resistance against Toxoplasma gondii
    • Flores, M., et al. 2008. Macrophage migration inhibitory factor (MIF) is critical for the host resistance against Toxoplasma gondii. FASEB J. 22:3661-3671.
    • (2008) FASEB J , vol.22 , pp. 3661-3671
    • Flores, M.1
  • 12
    • 34547200189 scopus 로고    scopus 로고
    • Discovery of parasite virulence genes reveals a unique regulator of chromosome condensation 1 ortholog critical for efficient nuclear trafficking
    • Frankel, M. B., D. G. Mordue, and L. J. Knoll. 2007. Discovery of parasite virulence genes reveals a unique regulator of chromosome condensation 1 ortholog critical for efficient nuclear trafficking. Proc. Natl. Acad. Sci. U. S. A. 104:10181-10186.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 10181-10186
    • Frankel, M.B.1    Mordue, D.G.2    Knoll, L.J.3
  • 13
    • 0027382381 scopus 로고
    • Host resistance to Toxoplasma gondii: model for studying the selective induction of cell-mediated immunity by intracellular parasites
    • Gazzinelli, R. T., E. Y. Denkers, and A. Sher. 1993. Host resistance to Toxoplasma gondii: model for studying the selective induction of cell-mediated immunity by intracellular parasites. Infect. Agents Dis. 2:139-149.
    • (1993) Infect. Agents Dis. , vol.2 , pp. 139-149
    • Gazzinelli, R.T.1    Denkers, E.Y.2    Sher, A.3
  • 14
    • 0014986716 scopus 로고
    • Resistance against Cryptococcus conferred by intracellular bacteria and protozoa
    • Gentry, L. O., and J. S. Remington. 1971. Resistance against Cryptococcus conferred by intracellular bacteria and protozoa. J. Infect. Dis. 123:22-31.
    • (1971) J. Infect. Dis. , vol.123 , pp. 22-31
    • Gentry, L.O.1    Remington, J.S.2
  • 15
    • 69249214151 scopus 로고    scopus 로고
    • Mixed infection and the genesis of influenza virus diversity
    • Ghedin, E., et al. 2009. Mixed infection and the genesis of influenza virus diversity. J. Virol. 83:8832-8841.
    • (2009) J. Virol. , vol.83 , pp. 8832-8841
    • Ghedin, E.1
  • 16
    • 77954761323 scopus 로고    scopus 로고
    • The 2009 A (H1N1) influenza virus pandemic: a review
    • Girard, M. P., J. S. Tam, O. M. Assossou, and M. P. Kieny. 2010. The 2009 A (H1N1) influenza virus pandemic: a review. Vaccine 28:4895-4902.
    • (2010) Vaccine , vol.28 , pp. 4895-4902
    • Girard, M.P.1    Tam, J.S.2    Assossou, O.M.3    Kieny, M.P.4
  • 17
    • 0142214635 scopus 로고    scopus 로고
    • Inhibition of HIV-1 infection by a CCR5-binding cyclophilin from Toxoplasma gondii
    • Golding, H., et al. 2003. Inhibition of HIV-1 infection by a CCR5-binding cyclophilin from Toxoplasma gondii. Blood 102:3280-3286.
    • (2003) Blood , vol.102 , pp. 3280-3286
    • Golding, H.1
  • 18
    • 0027485028 scopus 로고
    • Response to influenza infection in mice with a targeted disruption in the interferon gamma gene
    • Graham, M. B., et al. 1993. Response to influenza infection in mice with a targeted disruption in the interferon gamma gene. J. Exp. Med. 178:1725-1732.
    • (1993) J. Exp. Med. , vol.178 , pp. 1725-1732
    • Graham, M.B.1
  • 19
    • 57749187455 scopus 로고    scopus 로고
    • Developing new antiviral agents for influenza treatment: what does the future hold? Clin
    • Hayden, F. 2009. Developing new antiviral agents for influenza treatment: what does the future hold? Clin. Infect. Dis. 48(Suppl. 1):S3-S13.
    • (2009) Infect. Dis. , vol.48 , Issue.SUPPL. 1
    • Hayden, F.1
  • 20
    • 0027464928 scopus 로고
    • Immune response in mice that lack the interferongamma receptor
    • Huang, S., et al. 1993. Immune response in mice that lack the interferongamma receptor. Science 259:1742-1745.
    • (1993) Science , vol.259 , pp. 1742-1745
    • Huang, S.1
  • 21
    • 57449097438 scopus 로고    scopus 로고
    • Development of a vaccine against pandemic influenza viruses: current status and perspectives
    • Ilyinskii, P. O., G. Thoidis, and A. M. Shneider. 2008. Development of a vaccine against pandemic influenza viruses: current status and perspectives. Int. Rev. Immunol. 27:392-426.
    • (2008) Int. Rev. Immunol. , vol.27 , pp. 392-426
    • Ilyinskii, P.O.1    Thoidis, G.2    Shneider, A.M.3
  • 22
    • 33845405207 scopus 로고    scopus 로고
    • Inhibition of influenza virus infection by a novel antiviral peptide that targets viral attachment to cells
    • Jones, J. C., E. A. Turpin, H. Bultmann, C. R. Brandt, and S. Schultz-Cherry. 2006. Inhibition of influenza virus infection by a novel antiviral peptide that targets viral attachment to cells. J. Virol. 80:11960-11967.
    • (2006) J. Virol. , vol.80 , pp. 11960-11967
    • Jones, J.C.1    Turpin, E.A.2    Bultmann, H.3    Brandt, C.R.4    Schultz-Cherry, S.5
  • 23
    • 67649198507 scopus 로고    scopus 로고
    • Protective role for protease-activated receptor-2 against influenza virus pathogenesis via an IFN-γ-dependent pathway
    • Khoufache, K., et al. 2009. Protective role for protease-activated receptor-2 against influenza virus pathogenesis via an IFN-γ-dependent pathway. J. Immunol. 182:7795-7802.
    • (2009) J. Immunol. , vol.182 , pp. 7795-7802
    • Khoufache, K.1
  • 24
    • 54049111798 scopus 로고    scopus 로고
    • Influenza viruses and the NF-kappaB signaling pathway-towards a novel concept of antiviral therapy
    • Ludwig, S., and O. Planz. 2008. Influenza viruses and the NF-kappaB signaling pathway-towards a novel concept of antiviral therapy. Biol. Chem. 389:1307-1312.
    • (2008) Biol. Chem. , vol.389 , pp. 1307-1312
    • Ludwig, S.1    Planz, O.2
  • 25
    • 0017296746 scopus 로고
    • Acquired resistance to infection with Schistosoma mansoni induced by Toxoplasma gondii
    • Mahmoud, A. A., K. S. Warren, and G. T. Strickland. 1976. Acquired resistance to infection with Schistosoma mansoni induced by Toxoplasma gondii. Nature 263:56-57.
    • (1976) Nature , vol.263 , pp. 56-57
    • Mahmoud, A.A.1    Warren, K.S.2    Strickland, G.T.3
  • 26
    • 1542619262 scopus 로고    scopus 로고
    • T cell-intrinsic expression of c-Rel regulates Th1 cell responses essential for resistance to Toxoplasma gondii
    • Mason, N. J., H. C. Liou, and C. A. Hunter. 2004. T cell-intrinsic expression of c-Rel regulates Th1 cell responses essential for resistance to Toxoplasma gondii. J. Immunol. 172:3704-3711.
    • (2004) J. Immunol. , vol.172 , pp. 3704-3711
    • Mason, N.J.1    Liou, H.C.2    Hunter, C.A.3
  • 27
    • 33846043591 scopus 로고    scopus 로고
    • A patatin-like protein protects Toxoplasma gondii from degradation in activated macrophages
    • Mordue, D. G., C. F. Scott-Weathers, C. M. Tobin, and L. J. Knoll. 2007. A patatin-like protein protects Toxoplasma gondii from degradation in activated macrophages. Mol. Microbiol. 63:482-496.
    • (2007) Mol. Microbiol. , vol.63 , pp. 482-496
    • Mordue, D.G.1    Scott-Weathers, C.F.2    Tobin, C.M.3    Knoll, L.J.4
  • 28
    • 79251542671 scopus 로고    scopus 로고
    • A novel role for IFN-stimulated gene factor 3II in IFN-γ signaling and induction of antiviral activity in human cells
    • Morrow, A. N., H. Schmeisser, T. Tsuno, and K. C. Zoon. 2011. A novel role for IFN-stimulated gene factor 3II in IFN-γ signaling and induction of antiviral activity in human cells. J. Immunol. 186:1685-1693.
    • (2011) J. Immunol. , vol.186 , pp. 1685-1693
    • Morrow, A.N.1    Schmeisser, H.2    Tsuno, T.3    Zoon, K.C.4
  • 29
    • 0034570587 scopus 로고    scopus 로고
    • A systematic approach for establishing humane end-points
    • Morton, D. B. 2000. A systematic approach for establishing humane end-points. ILAR J. 41:80-86.
    • (2000) ILAR J , vol.41 , pp. 80-86
    • Morton, D.B.1
  • 30
    • 0029827404 scopus 로고    scopus 로고
    • Current and future clinical applications of interferongamma in host antimicrobial defense
    • Murray, H. W. 1996. Current and future clinical applications of interferongamma in host antimicrobial defense. Intensive Care Med. 22(Suppl. 4): S456-S461.
    • (1996) Intensive Care Med , vol.22 , Issue.SUPPL. 4
    • Murray, H.W.1
  • 31
    • 54049131196 scopus 로고    scopus 로고
    • RNA viruses and the mitogenic Raf/MEK/ERK signal transduction cascade
    • Pleschka, S. 2008. RNA viruses and the mitogenic Raf/MEK/ERK signal transduction cascade. Biol. Chem. 389:1273-1282.
    • (2008) Biol. Chem. , vol.389 , pp. 1273-1282
    • Pleschka, S.1
  • 32
    • 65549113423 scopus 로고    scopus 로고
    • Influenza virus resistance to antiviral agents: a plea for rational use
    • Poland, G. A., R. M. Jacobson, and I. G. Ovsyannikova. 2009. Influenza virus resistance to antiviral agents: a plea for rational use. Clin. Infect. Dis. 48:1254-1256.
    • (2009) Clin. Infect. Dis. , vol.48 , pp. 1254-1256
    • Poland, G.A.1    Jacobson, R.M.2    Ovsyannikova, I.G.3
  • 33
    • 0034003375 scopus 로고    scopus 로고
    • The role of alpha/beta and gamma interferons in development of immunity to influenza A virus in mice
    • Price, G. E., A. Gaszewska-Mastarlarz, and D. Moskophidis. 2000. The role of alpha/beta and gamma interferons in development of immunity to influenza A virus in mice. J. Virol. 74:3996-4003.
    • (2000) J. Virol. , vol.74 , pp. 3996-4003
    • Price, G.E.1    Gaszewska-Mastarlarz, A.2    Moskophidis, D.3
  • 34
    • 3042521047 scopus 로고    scopus 로고
    • Modulating TH1/TH2 responses with microbes, dendritic cells, and pathogen recognition receptors
    • Pulendran, B. 2004. Modulating TH1/TH2 responses with microbes, dendritic cells, and pathogen recognition receptors. Immunol. Res. 29:187-196.
    • (2004) Immunol. Res. , vol.29 , pp. 187-196
    • Pulendran, B.1
  • 35
    • 0014578637 scopus 로고
    • Resistance to virus challenge in mice infected with protozoa or bacteria
    • Remington, J. S., and T. C. Merigan. 1969. Resistance to virus challenge in mice infected with protozoa or bacteria. Proc. Soc. Exp. Biol. Med. 131:1184-1188.
    • (1969) Proc. Soc. Exp. Biol. Med. , vol.131 , pp. 1184-1188
    • Remington, J.S.1    Merigan, T.C.2
  • 37
    • 67650233633 scopus 로고    scopus 로고
    • Reducing the burden of influenza-associated complications with antiviral therapy
    • Ruf, B. R., and T. Szucs. 2009. Reducing the burden of influenza-associated complications with antiviral therapy. Infection 37:186-196.
    • (2009) Infection , vol.37 , pp. 186-196
    • Ruf, B.R.1    Szucs, T.2
  • 38
    • 0014403458 scopus 로고
    • Immunity and intracellular infection: resistance to bacteria in mice infected with a protozoan
    • Ruskin, J., and J. S. Remington. 1968. Immunity and intracellular infection: resistance to bacteria in mice infected with a protozoan. Science 160:72-74.
    • (1968) Science , vol.160 , pp. 72-74
    • Ruskin, J.1    Remington, J.S.2
  • 39
    • 71649113049 scopus 로고    scopus 로고
    • Toxoplasma gondii inhibits R5 HIV-1 replication in human lymphoid tissues ex vivo
    • Sassi, A., et al. 2009. Toxoplasma gondii inhibits R5 HIV-1 replication in human lymphoid tissues ex vivo. Microbes Infect. 11:1106-1113.
    • (2009) Microbes Infect , vol.11 , pp. 1106-1113
    • Sassi, A.1
  • 40
    • 0030294163 scopus 로고    scopus 로고
    • In the absence of endogenous IFN-gamma, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection
    • Scharton-Kersten, T. M., et al. 1996. In the absence of endogenous IFN-gamma, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection. J. Immunol. 157:4045-4054.
    • (1996) J. Immunol. , vol.157 , pp. 4045-4054
    • Scharton-Kersten, T.M.1
  • 41
    • 84954358205 scopus 로고    scopus 로고
    • Two ways to survive infection: what resistance and tolerance can teach us about treating infectious diseases
    • Schneider, D. S., and J. S. Ayres. 2008. Two ways to survive infection: what resistance and tolerance can teach us about treating infectious diseases. Nat. Rev. Immunol. 8:889-895.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 889-895
    • Schneider, D.S.1    Ayres, J.S.2
  • 42
    • 70350337437 scopus 로고    scopus 로고
    • An update on swine-origin influenza virus A/H1N1: a review
    • Schnitzler, S. U., and P. Schnitzler. 2009. An update on swine-origin influenza virus A/H1N1: a review. Virus Genes 39:279-292.
    • (2009) Virus Genes , vol.39 , pp. 279-292
    • Schnitzler, S.U.1    Schnitzler, P.2
  • 43
    • 26244445001 scopus 로고    scopus 로고
    • Interferon-gamma, the functional plasticity of the ubiquitin-proteasome system, and MHC class I antigen processing
    • Strehl, B., et al. 2005. Interferon-gamma, the functional plasticity of the ubiquitin-proteasome system, and MHC class I antigen processing. Immunol. Rev. 207:19-30.
    • (2005) Immunol. Rev. , vol.207 , pp. 19-30
    • Strehl, B.1
  • 44
    • 0023895411 scopus 로고
    • Interferon-gamma: the major mediator of resistance against Toxoplasma gondii
    • Suzuki, Y., M. A. Orellana, R. D. Schreiber, and J. S. Remington. 1988. Interferon-gamma: the major mediator of resistance against Toxoplasma gondii. Science 240:516-518.
    • (1988) Science , vol.240 , pp. 516-518
    • Suzuki, Y.1    Orellana, M.A.2    Schreiber, R.D.3    Remington, J.S.4
  • 45
    • 33750743068 scopus 로고    scopus 로고
    • Dissecting natural killer cell activation pathways through analysis of genetic mutations in human and mouse
    • Tassi, I., J. Klesney-Tait, and M. Colonna. 2006. Dissecting natural killer cell activation pathways through analysis of genetic mutations in human and mouse. Immunol. Rev. 214:92-105.
    • (2006) Immunol. Rev. , vol.214 , pp. 92-105
    • Tassi, I.1    Klesney-Tait, J.2    Colonna, M.3
  • 46
    • 0034051290 scopus 로고    scopus 로고
    • Depletion of lymphocytes and diminished cytokine production in mice infected with a highly virulent influenza A (H5N1) virus isolated from humans
    • Tumpey, T. M., X. Lu, T. Morken, S. R. Zaki, and J. M. Katz. 2000. Depletion of lymphocytes and diminished cytokine production in mice infected with a highly virulent influenza A (H5N1) virus isolated from humans. J. Virol. 74:6105-6116.
    • (2000) J. Virol. , vol.74 , pp. 6105-6116
    • Tumpey, T.M.1    Lu, X.2    Morken, T.3    Zaki, S.R.4    Katz, J.M.5
  • 47
    • 33847625418 scopus 로고    scopus 로고
    • Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46
    • Walzer, T., et al. 2007. Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46. Proc. Natl. Acad. Sci. U. S. A. 104:3384-3389.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 3384-3389
    • Walzer, T.1
  • 48
    • 77953546692 scopus 로고    scopus 로고
    • IFN-gamma treatment at early stages of influenza virus infection protects mice from death in a NK cell-dependent manner
    • Weiss, I. D., et al. 2010. IFN-gamma treatment at early stages of influenza virus infection protects mice from death in a NK cell-dependent manner. J. Interferon Cytokine Res. 30:439-449.
    • (2010) J. Interferon Cytokine Res. , vol.30 , pp. 439-449
    • Weiss, I.D.1
  • 49
    • 0035139418 scopus 로고    scopus 로고
    • Production of interferon-gamma by influenza hemagglutinin-specific CD8 effector T cells influences the development of pulmonary immunopathology
    • Wiley, J. A., A. Cerwenka, J. R. Harkema, R. W. Dutton, and A. G. Harmsen. 2001. Production of interferon-gamma by influenza hemagglutinin-specific CD8 effector T cells influences the development of pulmonary immunopathology. Am. J. Pathol. 158:119-130.
    • (2001) Am. J. Pathol. , vol.158 , pp. 119-130
    • Wiley, J.A.1    Cerwenka, A.2    Harkema, J.R.3    Dutton, R.W.4    Harmsen, A.G.5
  • 50
    • 4544236624 scopus 로고    scopus 로고
    • The absence of IFN-gamma leads to increased Th2 responses after influenza A virus infection characterized by an increase in CD4+ but not CD8+ T cells producing IL-4 or IL-5 in the lung
    • Wohlleben, G., and K. J. Erb. 2004. The absence of IFN-gamma leads to increased Th2 responses after influenza A virus infection characterized by an increase in CD4+ but not CD8+ T cells producing IL-4 or IL-5 in the lung. Immunol. Lett. 95:161-166.
    • (2004) Immunol. Lett. , vol.95 , pp. 161-166
    • Wohlleben, G.1    Erb, K.J.2
  • 51
    • 77951788536 scopus 로고    scopus 로고
    • Clinical aspects of pandemic 2009 influenza A (H1N1) virus infection
    • Writing Committee of the WHO Consultation on Clinical Aspects of Pandemic (H1N1) 2009 Influenza. 2010
    • Writing Committee of the WHO Consultation on Clinical Aspects of Pandemic (H1N1) 2009 Influenza. 2010. Clinical aspects of pandemic 2009 influenza A (H1N1) virus infection. N. Engl. J. Med. 362:1708-1719.
    • (2010) N. Engl. J. Med. , vol.362 , pp. 1708-1719


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.