Molecular and therapeutic characterization of anti-ectodysplasin A receptor (EDAR) agonist monoclonal antibodies

Journal of Biological Chemistry

Volumn 286, Issue 35, 2011, Pages 30769-30779

  Kowalczyk, Christine ^a   Dunkel, Nathalie ^a,i   Willen, Laure ^a   Casal, Margret L ^b   Mauldin, Elizabeth A ^b   Gaide, Olivier ^c   Tardivel, Aubry ^a   Badic, Giovanna ^a,j   Etter, Anne Lise ^d,k   Favre, Manuel ^d,l   Jefferson, Douglas M ^e,f   Headon, Denis J ^g   Demotz, Stéphane ^d,h,m   Schneider, Pascal ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF GENEVA   (Switzerland)

^d Apoxis SA   (Switzerland)

^e Cell Essential   (United States)

^f TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF EDINBURGH   (United Kingdom)

^h Edimer Biotech   (Switzerland)

ⁱ GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^j Instrumat AG   (Switzerland)

^k Celgene International   (Switzerland)

^l Merck Serono   (Switzerland)

^m Philip Morris Products SA   (Switzerland)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVITY ASSAYS; ADULT MICE; APOPTOTIC; DISSOCIATION CONSTANT; ECTODYSPLASIN; EXTRACELLULAR DOMAINS; IN-VITRO; THERAPEUTIC ACTIVITY; VERTEBRATE SPECIES;

DISSOCIATION; GENES; MONOCLONAL ANTIBODIES; SURFACE PLASMON RESONANCE;

MAMMALS;

ECTODYSPLASIN A; EDAR RECEPTOR; MONOCLONAL ANTIBODY;

APOPTOSIS; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CROSS REACTION; DISSOCIATION CONSTANT; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYPOHIDROTIC ECTODERMAL DYSPLASIA; IN VITRO STUDY; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PURIFICATION; SIGNAL TRANSDUCTION;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL SEPARATION; CHICKENS; DOGS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; FLOW CYTOMETRY; HUMANS; LIGANDS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PHENOTYPE; PLASMIDS; RATS; RECEPTORS, ECTODYSPLASIN; SURFACE PLASMON RESONANCE; TOOTH; TUMOR NECROSIS FACTOR-ALPHA;

CANIS FAMILIARIS; MUS; RATTUS; VERTEBRATA;

EID: 80052256976     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.267997     Document Type: Article

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