Biological activity of ectodysplasin A is conditioned by its collagen and heparan sulfate proteoglycan-binding domains

Journal of Biological Chemistry

Volumn 284, Issue 40, 2009, Pages 27567-27576

  Swee, Lee Kim ^a,d   Ingold Salamin, Karine ^a,e   Tardivel, Aubry ^a   Willen, Laure ^a   Gaide, Olivier ^a,f   Favre, Manuel ^c,g   Demotz, Stéphane ^c,h   Mikkola, Marja ^b   Schneider, Pascal ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c Apoxis SA   (Switzerland)

^d UNIVERSITY OF BASEL   (Switzerland)

^e LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^f UNIVERSITY OF GENEVA   (Switzerland)

^g Merck Serono   (Switzerland)

^h Edimer Biotech   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ABILITIES; BINDING DOMAIN; BIOLOGICAL ACTIVITIES; CELL LINES; ECTODYSPLASIN; HEPARAN SULFATES; HOMOLOGY DOMAIN; IN-VIVO; MULTIMERIZATION; PROTEOGLYCANS; PROTEOLYTIC PROCESSING; THERMAL STABILITY; WILD TYPES;

AMINES; AMINO ACIDS; CELL CULTURE; CELL MEMBRANES; ENZYME ACTIVITY; OLIGOMERIZATION; ORGANIC ACIDS; THERMODYNAMIC STABILITY;

COLLAGEN;

COLLAGEN; ECTODYSPLASIN A; EDAR RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEOHEPARAN SULFATE; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR 1; ANTIBODY; CROSS LINKING REAGENT; ECTODYSPLASIN RECEPTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; FRAMESHIFT MUTATION; GENE DELETION; GENE SEQUENCE; HUMAN; HUMAN CELL; MUTATIONAL ANALYSIS; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; THERMOSTABILITY; WILD TYPE; AMINO ACID SEQUENCE; ANIMAL; CELL DEATH; CELL LINE; CHEMISTRY; CYTOLOGY; EMBRYO DEVELOPMENT; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; GROWTH, DEVELOPMENT AND AGING; HAIR; KERATINOCYTE; METABOLISM; MOUSE; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; TAIL;

MUS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; CELL DEATH; CELL LINE; COLLAGEN; CROSS-LINKING REAGENTS; ECTODYSPLASINS; EMBRYONIC DEVELOPMENT; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; HAIR; HEPARAN SULFATE PROTEOGLYCANS; HUMANS; KERATINOCYTES; MICE; NF-KAPPA B; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ECTODYSPLASIN; TAIL;

EID: 70350446680     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.042259     Document Type: Article

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