Paired mutations abolish and restore the balanced annealing and melting activities of ORF1p that are required for LINE-1 retrotransposition

Nucleic Acids Research

Volumn 39, Issue 13, 2011, Pages 5611-5621

  Evans, James D ^a   Peddigari, Suresh ^a   Chaurasiya, Kathy R ^b   Williams, Mark C ^b,c   Martin, Sandra L ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b Department of Physics ^*  (United States)

^c NORTHEASTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CHAPERONE; DNA; LYSINE; PHENYLALANINE; RIBOSOMAL PROTEIN L1; RNA;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BIOCHEMISTRY; CONTROLLED STUDY; DNA DENATURATION; GENE AMPLIFICATION; GENE DOSAGE; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; LONG INTERSPERSED REPEAT; LOSS OF FUNCTION MUTATION; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; RETROPOSON; RNA BINDING; STEADY STATE;

AMINO ACID SUBSTITUTION; ANIMALS; DNA; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; MICE; MUTATION; NUCLEIC ACID DENATURATION; RETROELEMENTS; RNA;

MAMMALIA;

EID: 80052235999     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkr171     Document Type: Article

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