A single amino acid substitution in ORF1 dramatically decreases L1 retrotransposition and provides insight into nucleic acid chaperone activity

Nucleic Acids Research

Volumn 36, Issue 18, 2008, Pages 5845-5854

  Martin, Sandra L ^a   Bushman, Diane ^a   Wang, Fei ^b   Li, Patrick Wai Lun ^a   Walker, Ann ^a   Cummiskey, Jessica ^a   Branciforte, Dan ^a   Williams, Mark C ^b  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b NORTHEASTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; GENE PRODUCT; PROTEIN ORF1; PROTEIN ORF2; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; ENZYME ACTIVITY; GENE FREQUENCY; GENE INSERTION; GENE INTERACTION; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN PURIFICATION; PROTEIN RNA BINDING; RETROPOSON;

AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; DNA; DNA-BINDING PROTEINS; KINETICS; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; MICE; MOLECULAR CHAPERONES; NUCLEIC ACID DENATURATION; RIBONUCLEOPROTEINS; RNA; RNA-BINDING PROTEINS;

MAMMALIA;

EID: 54549107984     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkn554     Document Type: Article

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