-
1
-
-
0027535754
-
Acute bacterial meningitis in adults - A review of 493 episodes
-
DOI 10.1056/NEJM199301073280104
-
Durand M.L., Calderwood S.B., Weber D.J., et al. Acute bacterial meningitis in adults. A review of 493 episodes. N Engl J Med 1993; 328:21-8. (Pubitemid 23011467)
-
(1993)
New England Journal of Medicine
, vol.328
, Issue.1
, pp. 21-28
-
-
Durand, M.L.1
Calderwood, S.B.2
Weber, D.J.3
Miller, S.I.4
Southwick, F.S.5
Caviness Jr., V.S.6
Swartz, M.N.7
-
2
-
-
0036141405
-
2 mediate brain cell apoptosis during meningitis
-
DOI 10.1172/JCI200212035
-
Braun J.S., Sublett J.E., Freyer D., et al. Pneumococcal pneumolysin and H(2)O(2) mediate brain cell apoptosis during meningitis. J Clin Invest 2002; 109:19-27. (Pubitemid 34052538)
-
(2002)
Journal of Clinical Investigation
, vol.109
, Issue.1
, pp. 19-27
-
-
Braun, J.S.1
Sublett, J.E.2
Freyer, D.3
Mitchell, T.J.4
Cleveland, J.L.5
Tuomanen, E.I.6
Weber, J.R.7
-
3
-
-
58149291495
-
Rapid microtubule bundling and stabilization by the Streptococcus pneumoniae neurotoxin pneumolysin in a cholesterol-dependent, non-lytic and Src-kinase dependent manner inhibits intracellular trafficking
-
Iliev A.I., Djannatian J.R., Opazo F., et al. Rapid microtubule bundling and stabilization by the Streptococcus pneumoniae neurotoxin pneumolysin in a cholesterol-dependent, non-lytic and Src-kinase dependent manner inhibits intracellular trafficking. Mol Microbiol 2009;71:461-77.
-
(2009)
Mol Microbiol
, vol.71
, pp. 461-477
-
-
Iliev, A.I.1
Djannatian, J.R.2
Opazo, F.3
-
4
-
-
33847298089
-
Cholesterol-dependent actin remodeling via RhoA and Rac1 activation by the Streptococcus pneumoniae toxin pneumolysin
-
Iliev A.I., Djannatian J.R., Nau R., Mitchell T.J., Wouters F.S. Cholesterol-dependent actin remodeling via RhoA and Rac1 activation by the Streptococcus pneumoniae toxin pneumolysin. Proc Natl Acad Sci USA 2007; 104:2897-02.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 2897-2902
-
-
Iliev, A.I.1
Djannatian, J.R.2
Nau, R.3
Mitchell, T.J.4
Wouters, F.S.5
-
5
-
-
79751480235
-
Bacterial pore-forming cytolysins induce neuronal damage in a rat model of neonatal meningitis
-
Reiss A., Braun J.S., Jäger K., et al. Bacterial pore-forming cytolysins induce neuronal damage in a rat model of neonatal meningitis. J Infect Dis 2011; 203:393-400.
-
(2011)
J Infect Dis
, vol.203
, pp. 393-400
-
-
Reiss, A.1
Braun, J.S.2
Jäger, K.3
-
6
-
-
40549088892
-
Streptococcus pneumoniae deficient in pneumolysin or autolysin has reduced virulence in meningitis
-
DOI 10.1086/527322
-
Hirst R.A., Gosai B., Rutman A., et al. Streptococcus pneumoniae deficient in pneumolysin or autolysin has reduced virulence in meningitis. J Infect Dis 2008; 197:744-51. (Pubitemid 351364477)
-
(2008)
Journal of Infectious Diseases
, vol.197
, Issue.5
, pp. 744-751
-
-
Hirst, R.A.1
Gosai, B.2
Rutman, A.3
Guerin, C.J.4
Nicotera, P.5
Andrew, P.W.6
O'Callaghan, C.7
-
7
-
-
0036840362
-
Decreased virulence of a pneumolysin-deficient strain of Streptococcus pneumoniae in murine meningitis
-
Wellmer A., Zysk G., Gerber J., et al. Decreased virulence of a pneumolysin-deficient strain of Streptococcus pneumoniae in murine meningitis. Infect Immun 2002; 70:6504-8.
-
(2002)
Infect Immun
, vol.70
, pp. 6504-6508
-
-
Wellmer, A.1
Zysk, G.2
Gerber, J.3
-
8
-
-
0041767440
-
Reduced release of pneumolysin by Streptococcus pneumoniae in vitro and in vivo after treatment with nonbacteriolytic antibiotics in comparison to ceftriaxone
-
Spreer A., Kerstan H., Bottcher T., et al. Reduced release of pneumolysin by Streptococcus pneumoniae in vitro and in vivo after treatment with nonbacteriolytic antibiotics in comparison to ceftriaxone. Antimicrob Agents Chemother 2003; 47:2649-54.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 2649-2654
-
-
Spreer, A.1
Kerstan, H.2
Bottcher, T.3
-
9
-
-
0037002443
-
Neurotoxicity of pneumolysin, a major pneumococcal virulence factor, involves calcium influx and depends on activation of p38 mitogen-activated protein kinase
-
DOI 10.1006/nbdi.2002.0561
-
Stringaris A.K., Geisenhainer J., Bergmann F., et al. Neurotoxicity of pneumolysin, a major pneumococcal virulence factor, involves calcium influx and depends on activation of p38 mitogen-activated protein kinase. Neurobiol Dis 2002; 11:355-68. (Pubitemid 36269122)
-
(2002)
Neurobiology of Disease
, vol.11
, Issue.3
, pp. 355-368
-
-
Stringaris, A.K.1
Geisenhainer, J.2
Bergmann, F.3
Balshusemann, C.4
Lee, U.5
Zysk, G.6
Mitchell, T.J.7
Keller, B.U.8
Kuhnt, U.9
Gerber, J.10
Spreer, A.11
Bahr, M.12
Michel, U.13
Nau, R.14
-
10
-
-
17444405610
-
Structural basis of pore formation by the bacterial toxin pneumolysin
-
DOI 10.1016/j.cell.2005.02.033
-
Tilley S.J., Orlova E.V., Gilbert R.J., Andrew P.W., Saibil H.R. Structural basis of pore formation by the bacterial toxin pneumolysin. Cell 2005; 121:247-56. (Pubitemid 40546392)
-
(2005)
Cell
, vol.121
, Issue.2
, pp. 247-256
-
-
Tilley, S.J.1
Orlova, E.V.2
Gilbert, R.J.C.3
Andrew, P.W.4
Saibil, H.R.5
-
11
-
-
0026695462
-
Differential sensitivity of pneumolysin-induced channels to gating by divalent cations
-
Korchev Y.E., Bashford C.L., Pasternak C.A. Differential sensitivity of pneumolysin-induced channels to gating by divalent cations. J Membr Biol 1992; 127:195-203.
-
(1992)
J Membr Biol
, vol.127
, pp. 195-203
-
-
Korchev, Y.E.1
Bashford, C.L.2
Pasternak, C.A.3
-
12
-
-
0032007852
-
A conserved tryptophan in pneumolysin is a determinant of the characteristics of channels formed by pneumolysin in cells and planar lipid bilayers
-
Korchev Y.E., Bashford C.L., Pederzolli C., et al. A conserved tryptophan in pneumolysin is a determinant of the characteristics of channels formed by pneumolysin in cells and planar lipid bilayers. Biochem J 1998; 329:571-7.
-
(1998)
Biochem J
, vol.329
, pp. 571-577
-
-
Korchev, Y.E.1
Bashford, C.L.2
Pederzolli, C.3
-
13
-
-
17644428099
-
Pneumolysin-mediated activation of NFkappaB in human neutrophils is antagonized by docosahexaenoic acid
-
DOI 10.1111/j.1365-2249.2005.02757.x
-
Fickl H., Cockeran R., Steel H.C., et al. Pneumolysin-mediated activation of NFkappaB in human neutrophils is antagonized by docosahexaenoic acid. Clin Exp Immunol 2005; 140:274-81. (Pubitemid 40559153)
-
(2005)
Clinical and Experimental Immunology
, vol.140
, Issue.2
, pp. 274-281
-
-
Fickl, H.1
Cockeran, R.2
Steel, H.C.3
Feldman, C.4
Cowan, G.5
Mitchell, T.J.6
Anderson, R.7
-
14
-
-
37249064163
-
Zinc protection against pneumolysin toxicity on rat cochlear hair cells
-
DOI 10.1159/000108763
-
Franco-Vidal V., Beurg M., Darrouzet V., Bebear J.P., Skinner L.J., Dulon D. Zinc protection against pneumolysin toxicity on rat cochlear hair cells. Audiol Neuro-otol 2008; 13:65-70. (Pubitemid 350275264)
-
(2008)
Audiology and Neurotology
, vol.13
, Issue.1
, pp. 65-70
-
-
Franco-Vidal, V.1
Beurg, M.2
Darrouzet, V.3
Bebear, J.-P.4
Skinner, L.J.5
Dulon, D.6
-
15
-
-
0022566935
-
Interstitial ion concentrations and paroxysmal discharges in hippocampal formation and spinal cord
-
Somjen G.G., Aitken P.G., Giacchino J.L., McNamara J.O. Interstitial ion concentrations and paroxysmal discharges in hippocampal formation and spinal cord. Adv Neurol 1986; 44:663-80.
-
(1986)
Adv Neurol
, vol.44
, pp. 663-680
-
-
Somjen, G.G.1
Aitken, P.G.2
Giacchino, J.L.3
McNamara, J.O.4
-
16
-
-
77949657612
-
Novel mucosal vaccines generated by genetic conjugation of heterologous proteins to pneumolysin (PLY) from Streptococcus pneumoniae
-
Douce G., Ross K., Cowan G., Ma J., Mitchell T.J. Novel mucosal vaccines generated by genetic conjugation of heterologous proteins to pneumolysin (PLY) from Streptococcus pneumoniae. Vaccine 2010; 28: 3231-7.
-
(2010)
Vaccine
, vol.28
, pp. 3231-3237
-
-
Douce, G.1
Ross, K.2
Cowan, G.3
Ma, J.4
Mitchell, T.J.5
-
17
-
-
1442314700
-
Neuronal injury mediated via stimulation of microglial toll-like receptor-9 (TLR9)
-
Iliev A.I., Stringaris A.K., Nau R., Neumann H. Neuronal injury mediated via stimulation of microglial toll-like receptor-9 (TLR9). Faseb J 2004; 18:412-4.
-
(2004)
Faseb J
, vol.18
, pp. 412-414
-
-
Iliev, A.I.1
Stringaris, A.K.2
Nau, R.3
Neumann, H.4
-
18
-
-
0018139740
-
Formation of large, ion-permeable membrane channels by the matrix protein (porin) of Escherichia coli
-
Benz R., Janko K., Boos W., Lauger P. Formation of large, ion-permeable membrane channels by the matrix protein (porin) of Escherichia coli. Biochim Biophys Acta 1978; 511:305-19. (Pubitemid 8404294)
-
(1978)
Biochimica et Biophysica Acta
, vol.511
, Issue.3
, pp. 305-319
-
-
Benz, R.1
Janko, K.2
Boos, W.3
Laeuger, P.4
-
19
-
-
0019214630
-
Determination of ion permeability through the channels made of porins from the outer membrane of Salmonella typhimurium in lipid bilayer membranes
-
Benz R., Ishii J., Nakae T. Determination of ion permeability through the channels made of porins from the outer membrane of Salmonella typhimurium in lipid bilayer membranes. J Membr Biol 1980; 56: 19-29. (Pubitemid 11250333)
-
(1980)
Journal of Membrane Biology
, vol.56
, Issue.1
, pp. 19-29
-
-
Benz, R.1
Ishii, J.2
Nakae, T.3
-
20
-
-
79952169974
-
Changes in astrocyte shape induced by sublytic concentrations of the cholesterol-dependent cytolysin pneumolysin still require pore-forming capacity
-
Förtsch C., Hupp S., Ma J., et al. Changes in astrocyte shape induced by sublytic concentrations of the cholesterol-dependent cytolysin pneumolysin still require pore-forming capacity. Toxins 2011; 3:43-62.
-
(2011)
Toxins
, vol.3
, pp. 43-62
-
-
Förtsch, C.1
Hupp, S.2
Ma, J.3
-
21
-
-
26844580088
-
The mechanism of pneumolysin-induced cochlear hair cell death in the rat
-
DOI 10.1113/jphysiol.2005.092478
-
Beurg M., Hafidi A., Skinner L., et al. The mechanism of pneumolysin-induced cochlear hair cell death in the rat. J Physiol 2005; 568:211-27. (Pubitemid 41448632)
-
(2005)
Journal of Physiology
, vol.568
, Issue.1
, pp. 211-227
-
-
Beurg, M.1
Hafidi, A.2
Skinner, L.3
Cowan, G.4
Hondarrague, Y.5
Mitchell, T.J.6
Dulon, D.7
-
22
-
-
0028157360
-
Metal ions affect neuronal membrane fluidity of rat cerebral cortex
-
Ohba S., Hiramatsu M., Edamatsu R., Mori I., Mori A. Metal ions affect neuronal membrane fluidity of rat cerebral cortex. Neurochem Res 1994; 19:237-41. (Pubitemid 24054792)
-
(1994)
Neurochemical Research
, vol.19
, Issue.3
, pp. 237-241
-
-
Ohba, S.1
Hiramatsu, M.2
Edamatsu, R.3
Mori, I.4
Mori, A.5
-
23
-
-
0018707385
-
Reversible electrical breakdown of lipid bilayer membranes: A charge-pulse relaxation study
-
DOI 10.1007/BF01872858
-
Benz R., Beckers F., Zimmermann U. Reversible electrical breakdown of lipid bilayer membranes: a charge-pulse relaxation study. J Membr Biol 1979; 48:181-204. (Pubitemid 10236612)
-
(1979)
Journal of Membrane Biology
, vol.48
, Issue.2
, pp. 181-204
-
-
Benz, R.1
Beckers, F.2
Zimmermann, U.3
-
24
-
-
0029019589
-
Cholesterol oxidation reduces Ca(2+)+MG (2+)-ATPase activity, interdigitation, and increases fluidity of brain synaptic plasma membranes
-
Wood W.G., Igbavboa U., Rao A.M., Schroeder F., Avdulov N.A. Cholesterol oxidation reduces Ca(2+)+MG (2+)-ATPase activity, interdigitation, and increases fluidity of brain synaptic plasma membranes. Brain Res 1995; 683:36-42.
-
(1995)
Brain Res
, vol.683
, pp. 36-42
-
-
Wood, W.G.1
Igbavboa, U.2
Rao, A.M.3
Schroeder, F.4
Avdulov, N.A.5
-
25
-
-
34047134164
-
The role of extracellular calcium in exo- and endocytosis of synaptic vesicles at the frog motor nerve terminals
-
DOI 10.1016/j.neuroscience.2006.08.025, PII S0306452206011092
-
Zefirov A.L., Abdrakhmanov M.M., Mukhamedyarov M.A., Grigoryev P.N. The role of extracellular calcium in exo- and endocytosis of synaptic vesicles at the frog motor nerve terminals. Neuroscience 2006; 143: 905-10. (Pubitemid 44827515)
-
(2006)
Neuroscience
, vol.143
, Issue.4
, pp. 905-910
-
-
Zefirov, A.L.1
Abdrakhmanov, M.M.2
Mukhamedyarov, M.A.3
Grigoryev, P.N.4
-
26
-
-
21344436393
-
Extracellular calcium is required for the maintenance of plasma membrane integrity in nucleated cells
-
DOI 10.1016/j.ceca.2005.03.006, PII S0143416005000709
-
Orlov S.N., Aksentsev S.L., Kotelevtsev S.V. Extracellular calcium is required for the maintenance of plasma membrane integrity in nucleated cells. Cell Calcium 2005; 38:53-7. (Pubitemid 40903760)
-
(2005)
Cell Calcium
, vol.38
, Issue.1
, pp. 53-57
-
-
Orlov, S.N.1
Aksentsev, S.L.2
Kotelevtsev, S.V.3
-
27
-
-
0034523349
-
Cations of cisternal cerebrospinal fluid in humans and the effect of different doses of nimodipine on CSF calcium after stroke
-
DOI 10.1097/00002826-200011000-00004
-
Bereczki D., Fekete I., Loof I., et al. Cations of cisternal cerebrospinal fluid in humans and the effect of different doses of nimodipine on CSF calcium after stroke. Clin Neuropharmacol 2000; 23:318-23. (Pubitemid 32047013)
-
(2000)
Clinical Neuropharmacology
, vol.23
, Issue.6
, pp. 318-323
-
-
Bereczki, D.1
Fekete, I.2
Loof, I.3
Kobberling, W.4
Valikovics, A.5
Nemeth, G.6
Fulesdi, B.7
Csiba, L.8
-
28
-
-
0023728908
-
Brain fluid calcium concentration and response to acute hypercalcaemia during development in the rat
-
Jones H.C., Keep R.F. Brain fluid calcium concentration and response to acute hypercalcaemia during development in the rat. J Physiol 1988; 402:579-93.
-
(1988)
J Physiol
, vol.402
, pp. 579-593
-
-
Jones, H.C.1
Keep, R.F.2
-
29
-
-
0020211569
-
Altered sensorium in neurological infections and the homeostasis of Mg, Zn, Cu and Ca
-
DOI 10.1016/0048-9697(82)90020-1
-
Pandey V.K., Parmeswaran M., Soman S.D., Dacosta H.J. Altered sensorium in neurological infections and the homeostasis of Mg, Zn, Cu and Ca. Sci Total Environ 1982; 25:277-85. (Pubitemid 13196790)
-
(1982)
Science of the Total Environment
, vol.25
, Issue.3
, pp. 277-285
-
-
Pandey, V.K.1
Parmeswaran, M.2
Soman, S.D.3
Dacosta, H.J.4
-
30
-
-
0036212840
-
Invasive group A streptococcal infections in a large tertiary center: Epidemiology, characteristics and outcome
-
DOI 10.1007/s15010-002-1182-6
-
Ben-Abraham R., Keller N., Vered R., Harel R., Barzilay Z., Paret G. Invasive group A streptococcal infections in a large tertiary center: Epidemiology, characteristics and outcome. Infection 2002; 30:81-5. (Pubitemid 34293371)
-
(2002)
Infection
, vol.30
, Issue.2
, pp. 81-85
-
-
Ben-Abraham, R.1
Keller, N.2
Vered, R.3
Harel, R.4
Barzilay, Z.5
Paret, G.6
-
31
-
-
0032160842
-
Group B streptococcal bacteremia in adults at Hartford Hospital 1991-1996
-
Cooper B.W., Morganelli E. Group B streptococcal bacteremia in adults at Hartford Hospital 1991-1996. Conn Med 1998; 62:515-7.
-
(1998)
Conn Med
, vol.62
, pp. 515-517
-
-
Cooper, B.W.1
Morganelli, E.2
-
32
-
-
0018917907
-
Binding of cholesterol by sulfhydryl-activated cytolysins
-
Johnson M.K., Geoffroy C., Alouf J.E. Binding of cholesterol by sulfhydryl-activated cytolysins. Infect Immun 1980; 27:97-101. (Pubitemid 10211942)
-
(1980)
Infection and Immunity
, vol.27
, Issue.1
, pp. 97-101
-
-
Johnson, M.K.1
Geoffroy, C.2
Alouf, J.E.3
-
33
-
-
0023245747
-
The multifactorial basis for hypocalcemia during sepsis. Studies on the parathyroid hormone-vitamin D axis
-
Zaloga G.P., Chernow B. The multifactorial basis for hypocalcemia during sepsis. Studies of the parathyroid hormone-vitamin D axis. Ann Intern Med 1987; 107:36-41. (Pubitemid 17098634)
-
(1987)
Annals of Internal Medicine
, vol.107
, Issue.1
, pp. 36-41
-
-
Zaloga, G.P.1
Chernow, B.2
|