Role of shear stress and stretch in vascular mechanobiology

Journal of the Royal Society Interface

Volumn 8, Issue 63, 2011, Pages 1379-1385

  Lu, Deshun ^a   Kassab, Ghassan S ^a  

^a Indiana University Purdue University Indianapolis   (United States)

Author keywords

Circumferential stretch; Endothelial cells; Laminar shear stress; Mechanical transduction; Oxidative stress; Smooth muscle cells

Indexed keywords

BLOOD; BLOOD PRESSURE; BLOOD VESSELS; ELASTICITY; ENDOTHELIAL CELLS; NITRIC OXIDE; PHYSIOLOGY; SHEAR FLOW; SHEAR STRESS; STRUCTURAL DESIGN; TISSUE;

BIOCHEMICAL PATHWAY; BLOOD VESSEL WALLS; CIRCUMFERENTIAL STRETCH; CIRCUMFERENTIAL WALL STRESS; LAMINAR SHEAR STRESS; MECHANICAL FORCE; MECHANICAL LOADING; MECHANICAL TRANSDUCTION; MECHANO-BIOLOGY; MOLECULAR PATHWAYS; MORPHOLOGICAL CHANGES; SMOOTH MUSCLE CELLS; STRESS AND STRETCH; TISSUE STRESS; VASOPROTECTIVE; VASORELAXATION;

STRESS ANALYSIS;

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN II; CD31 ANTIGEN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC GMP DEPENDENT PROTEIN KINASE; CYCLOOXYGENASE 2; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FOCAL ADHESION KINASE; INTEGRIN; MESSENGER RNA; MYELOPEROXIDASE; NITRIC OXIDE; PAXILLIN; PEROXYNITRITE; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTACYCLIN; PROSTAGLANDIN SYNTHASE; PROTEIN P47; RAC PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RHO KINASE; SUPEROXIDE; TISSUE PLASMINOGEN ACTIVATOR; VASCULAR ENDOTHELIAL CADHERIN; VASCULOTROPIN RECEPTOR 2; XANTHINE OXIDASE;

ACTIN POLYMERIZATION; BIOAVAILABILITY; BLOOD PRESSURE; BLOOD VESSEL COMPLIANCE; BLOOD VESSEL DIAMETER; BLOOD VESSEL WALL; ENDOTHELIAL DYSFUNCTION; ENDOTHELIAL SHEAR STRESS; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; EXTRACELLULAR MATRIX; HOMEOSTASIS; HUMAN; MECHANICAL STRESS; MOLECULAR INTERACTION; NONHUMAN; OXIDATIVE STRESS; PHYSICAL STRESS; PHYSIOLOGICAL STRESS; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REVIEW; SHEAR STRESS; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; UPREGULATION; VASCULAR BIOLOGY; VASCULAR MECHANOBIOLOGY; VASCULAR RESISTANCE; VASODILATATION;

EID: 80052211302     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2011.0177     Document Type: Review

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