Anti-inflammatory effects of garenoxacin on IL-8 production and ERK1/2 activation induced by lipopolysaccharides in A549 and THP-1 cells

European Journal of Pharmacology

Volumn 668, Issue 1-2, 2011, Pages 264-270

  Hara, Shintaro ^a   Ishimatsu, Yuji ^a   Mukae, Hiroshi ^b   Sakamoto, Noriho ^a   Kakugawa, Tomoyuki ^a   Fujita, Hanako ^a   Hara, Atsuko ^a   Kohno, Shigeru ^a  

^a NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

Fluoroquinolone; Immunomodulatory effect; Inflammatory cytokine; Macrolide; MAPK phosphorylation

Indexed keywords

AMPICILLIN; CLARITHROMYCIN; GARENOXACIN; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; TELITHROMYCIN;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL LINE; CELL STIMULATION; CELL STRAIN A549; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG EXPOSURE; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOMODULATION; MONOCYTE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT INFECTION; THP 1 CELL;

AMPICILLIN; ANTI-INFLAMMATORY AGENTS; CELL LINE; CLARITHROMYCIN; ENZYME ACTIVATION; FLUOROQUINOLONES; HUMANS; IMMUNOLOGIC FACTORS; INTERLEUKIN-8; KETOLIDES; LIPOPOLYSACCHARIDES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; RNA, MESSENGER;

EID: 80052056279     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.06.046     Document Type: Article

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